Evaluation of the retinal ganglion cell layer thickness in healthy Turkish children.

Abstract:

PURPOSE:To identify the distribution, variation, and determinants of ganglion cell-inner plexiform layer (GC-IPL) thickness in healthy Turkish children measured by high-definition optical coherence tomography (HD-OCT). PATIENTS AND METHODS:This institutional study involved 296 eyes from 296 healthy children aged between 3 and 17 years. Each child underwent a dilated eye examination, cycloplegic refraction, and axial length measurement using Nidek AL-Scan optical biometer. Macular scan was used to measure the GC-IPL thickness, and peripapillary retinal nerve fiber layer (RNFL) thickness was measured using the HD-OCT (Cirrus HD-OCT). Right eye of each subject was selected for analysis. RESULTS:A total of 296 children (125 boys, 171 girls) were included in this study. The mean age of the children was 9.62±4.10 years (range, 3 to 17 y). The mean spherical equivalent was -0.09±1.49 D. The mean AL was 23.03±1.03 mm. The mean overall GC-IPL thickness was 83.44±5.52 μm and RNFL thickness was 96.91±10.21 μm. They were thicker than has been reported in adults. According to age-adjusted multiple regression analyses significant predictors of mean GC-IPL thickness were peripapillary RNFL thickness and AL (P<0.001). CONCLUSIONS:This study ensures a pediatric normative database of GC-IPL using spectral-domain OCT. This information may provide to diagnosis and monitoring of optic nerve diseases and glaucoma in children.

journal_name

J Glaucoma

journal_title

Journal of glaucoma

authors

Totan Y,Gürağaç FB,Güler E

doi

10.1097/IJG.0000000000000168

subject

Has Abstract

pub_date

2015-06-01 00:00:00

pages

e103-8

issue

5

eissn

1057-0829

issn

1536-481X

journal_volume

24

pub_type

杂志文章
  • Even-number Measurement Bias With Goldmann Applanation Tonometry.

    abstract::While working with a large data set of Goldmann applanation tonometry (GAT) intraocular pressure (IOP) measurements for a separate investigation, we observed that the IOP distribution favored even-numbered values. Study of this phenomenon has been limited, and this larger data set enabled inquiry that showed new insig...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001412

    authors: Rozwat A,Roberts DK

    更新日期:2020-02-01 00:00:00

  • Reproducibility of retinal nerve fiber thickness measurements using the test-retest function of spectral OCT/SLO in normal and glaucomatous eyes.

    abstract:PURPOSE:To evaluate the reproducibility of retinal nerve fiber layer (RNFL) thickness measurements in normal and glaucoma patients using the spectral optical coherence tomography (OCT)/scanning laser ophthalmosope (SLO). METHODS:One experienced operator measured peripapillary RNFL thickness 3 times in succession in 98...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3181ca7cbe

    authors: Lee SH,Kim SH,Kim TW,Park KH,Kim DM

    更新日期:2010-12-01 00:00:00

  • CO2 laser-assisted sclerectomy surgery, part II: multicenter clinical preliminary study.

    abstract:PURPOSE:To evaluate the efficacy of CO2 laser-assisted sclerectomy surgery (CLASS) in primary and pseudoexfoliative open-angle glaucoma. MATERIALS AND METHODS:Patients for primary filtration surgery underwent CLASS with a CO2 laser system (OT-134-IOPtiMate, IOPtima Ltd., Ramat Gan, Israel). This self-controlled system...

    journal_title:Journal of glaucoma

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1097/IJG.0b013e3181f7b14f

    authors: Geffen N,Ton Y,Degani J,Assia EI

    更新日期:2012-03-01 00:00:00

  • Mask-induced Artifact Impacts Intraocular Pressure Measurement Using Goldmann Applanation Tonometry.

    abstract:PURPOSE:The coronavirus (COVID-19) pandemic has impacted ophthalmology practices significantly. American Academy of Ophthalmology and Center for Disease Control guidelines suggest mandatory masking of patients and physicians during outpatient visits. We have recently become aware of a mask-induced phenomenon, whereby t...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001746

    authors: Davanian AM,Donahue SP,Mogil RS,Groth SL

    更新日期:2020-12-02 00:00:00

  • Glycerin-preserved Human-donor Corneoscleral Patch Grafts for Glaucoma Drainage Devices.

    abstract:PRECIS:Glycerin-preserved, human-donor, corneoscleral patch grafts are effective and safe for glaucoma drainage device (GDD) implantation, and they are comparable to previously reported materials. It can be preserved with the sterile technique for up to 12 months. PURPOSE:To evaluate the efficacy and safety of glyceri...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001610

    authors: Kitnarong N,Srikulsasitorn B,Aurboonsong T

    更新日期:2020-11-01 00:00:00

  • Static and Dynamic Pupillary Characteristics in Clinically Unilateral Pseudoexfoliation Syndrome.

    abstract:PURPOSE:The purpose of this study was to perform a comparison of static and dynamic pupillometry measurements in patients with clinically unilateral pseudoexfoliation syndrome (PES) and age-matched controls. METHODS:This prospective cross-sectional study consisted of 38 patients with unilateral PES and 40 control part...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000000953

    authors: Tekin K,Sekeroglu MA,Kiziltoprak H,Yetkin E,Doguizi S,Yilmazbas P

    更新日期:2018-06-01 00:00:00

  • Characteristics of peripapillary retinal nerve fiber layer thickness in eyes with myopic optic disc tilt and rotation.

    abstract:PURPOSE:The purpose of the study was to investigate the effects of myopic optic disc tilt and rotation on peripapillary retinal nerve fiber layer (RNFL) thickness characteristics measured by Cirrus HD spectral-domain optical coherence tomography (Cirrus HD OCT). METHODS:A total of 93 right eyes from 93 healthy young m...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3182182567

    authors: Hwang YH,Yoo C,Kim YY

    更新日期:2012-08-01 00:00:00

  • Frequency and risk factors for intraocular pressure elevation after posterior sub-Tenon capsule triamcinolone acetonide injection.

    abstract:PURPOSE:This study investigated the effects of posterior sub-Tenon capsule (PST) injection of triamcinolone acetonide (TA) on intraocular pressure (IOP) in the human eye. METHODS:The study included 115 patients who received PST injections of 40-mg TA to treat macular edema with diabetic retinopathy (n=57), branch reti...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e31802d696f

    authors: Iwao K,Inatani M,Kawaji T,Koga T,Mawatari Y,Tanihara H

    更新日期:2007-03-01 00:00:00

  • Influence of total energy delivery on success rate after contact diode laser transscleral cyclophotocoagulation: a retrospective case review and meta-analysis.

    abstract:PURPOSE:To evaluate the effect of a single treatment of contact diode laser transscleral cyclophotocoagulation (TSCP) on intraocular pressure (IOP) in patients with refractory glaucoma and perform a historical meta-analysis of the relationship between successful IOP control and various laser parameters. METHODS:Clinic...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,meta分析

    doi:10.1097/00061198-200208000-00009

    authors: Hauber FA,Scherer WJ

    更新日期:2002-08-01 00:00:00

  • Rate of response to latanoprost or timolol in patients with ocular hypertension or glaucoma.

    abstract:PURPOSE:This study determined the rate of response to latanoprost compared with timolol in patients with glaucoma or ocular hypertension, whether some patients convert from non-responders to responders after more prolonged therapy, and whether this conversion represents a delayed response or random fluctuation. METHOD...

    journal_title:Journal of glaucoma

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00061198-200312000-00004

    authors: Camras CB,Hedman K,US Latanoprost Study Group.

    更新日期:2003-12-01 00:00:00

  • Rasagiline-induced delay of retinal ganglion cell death in experimental glaucoma in rats.

    abstract:PURPOSE:To evaluate the neuroprotective effect of rasagiline (N-propargyl-1 (R)-aminoindan), a selective monoamine oxidase inhibitor, on the survival of retinal ganglion cells (RGCs) in glaucomatous rat eyes. Rasagiline is an FDA approved anti-Parkinson disease drug with neuroprotective capabilities that were shown in ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3181e3d101

    authors: Levkovitch-Verbin H,Vander S,Melamed S

    更新日期:2011-06-01 00:00:00

  • Association of Intraocular Pressure Changes With Right Ventricular Diameter and Brain Natriuretic Peptide in a Case of Pulmonary Arterial Hypertension.

    abstract:PURPOSE:To report a case of secondary pulmonary arterial hypertension (PAH) and the relationship of intraocular pressure (IOP) change with right ventricular diameter (RVD) and brain natriuretic peptide (BNP). METHODS:Case report. PATIENT:A 22-year-old woman with dilated and congested conjunctival and episcleral veins...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000000371

    authors: Sato C,Kaneko H,Kondo T,Takayama K,Yasuda S,Terasaki H

    更新日期:2016-03-01 00:00:00

  • Sterile single use cover for the G-probe Transscleral Cyclodiode.

    abstract:PURPOSE:Multiuse of the G-probe transscleral cyclophotocoagulation (TSCPC) device can lead to contamination. We evaluated the mechanical stability and clinical efficacy of a disposable sterile barrier for the G-probe footplate. METHODS:We measured diode laser output with and without the G-probe barrier both before and...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3181e08109

    authors: Rootman DB,Howarth D,Kerr JQ,Flanagan JG,Trope GE,Buys YM

    更新日期:2011-04-01 00:00:00

  • Systemic high-sensitivity C-reactive protein level in pseudoexfoliation syndrome and pseudoexfoliation glaucoma.

    abstract:PURPOSE:To evaluate the systemic high sensitivity C-reactive protein (hsCRP) levels in patients with pseudoexfoliation syndrome (XFS) and pseudoexfoliation glaucoma (XFG). MATERIALS AND METHODS:We prospectively examined 31 patients with XFS, 26 with XFG, and 25 controls. To the study patients with the exclusion of ser...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3181bdb570

    authors: Yüksel N,Pirhan D,Altintaş O,Cağlar Y

    更新日期:2010-08-01 00:00:00

  • The Association Between Macula and ONH Optical Coherence Tomography Angiography (OCT-A) Vessel Densities in Glaucoma, Glaucoma Suspect, and Healthy Eyes.

    abstract:PURPOSE:To evaluate strength of associations between optical coherence tomography (OCT)-angiography vessel density (VD) measurements in the macula and peripapillary region of the optic nerve head (ONH) with standard structural OCT thickness measures. MATERIALS AND METHODS:This cross-sectional study included 333 eyes o...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000000862

    authors: Manalastas PIC,Zangwill LM,Daga FB,Christopher MA,Saunders LJ,Shoji T,Akagi T,Penteado RC,Yarmohammadi A,Suh MH,Medeiros FA,Weinreb RN

    更新日期:2018-03-01 00:00:00

  • Optic Nerve Head Drusen: Imaging Using Optical Coherence Tomography Angiography.

    abstract:PURPOSE:To describe findings and utility of optical coherence tomography angiography (OCTA) in optic nerve head drusen (ONHD). OBSERVATIONS:A 57-year-old white man presented with a decrease in contrast sensitivity of the inferior visual field in both eyes. Clinical examination, visual fields, optical coherence tomogra...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000000730

    authors: Flores-Reyes E,Hoskens K,Mansouri K

    更新日期:2017-09-01 00:00:00

  • Juvenile Open Angle Glaucoma With Nonbullous Congenital Ichthyosiform Erythroderma.

    abstract:INTRODUCTION:Glaucoma in patients with nonbullous congenital ichthyosiform erythroderma (NBCIE) is a rare entity that has not been described in a histologically confirmed case. We present a unique case of coexisting glaucoma, ichthyosis, and dwarfism that has not been previously described. METHODS:We present a case of...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001016

    authors: Ichhpujani P,Thakur S,Kumar S,Singh RB

    更新日期:2018-11-01 00:00:00

  • Measurement of superficial optic nerve head capillary blood velocities by scanning laser fluorescein angiography.

    abstract::Scanning laser ophthalmoscopy is capable of producing video fluorescein angiograms with high spatial and temporal resolution. Digital image analysis of these angiograms has been used to produce measures of capillary flow velocities in perimacular capillaries. We have recently utilized the same technique to measure flo...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:

    authors: Cantor LB,Harris A,Wolf S,Sponsel WE,Arend O

    更新日期:1994-07-01 00:00:00

  • Outcomes of bleb excision with free autologous conjunctival patch grafting for bleb leak and hypotony after glaucoma filtering surgery.

    abstract:PURPOSE:To determine the outcomes of bleb excision with free autologous conjunctival patch grafting for bleb leak and hypotony after glaucoma filtering surgery. PATIENTS AND METHODS:Retrospective, consecutive, noncomparative case series. Outcome measures were closure of bleb leak, intraocular pressure (IOP), and best ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3181e87efc

    authors: Panday M,Shantha B,George R,Boda S,Vijaya L

    更新日期:2011-08-01 00:00:00

  • Relationship between pattern electroretinogram, standard automated perimetry, and optic nerve structural assessments.

    abstract:PURPOSE:To examine the relationship between retinal ganglion cell function measured using pattern electroretinogram optimized for glaucoma screening (PERGLA), retinal nerve fiber layer (RNFL) thickness, and optic nerve head topography. METHODS:Twenty-nine normal, 28 glaucoma, and 37 glaucoma suspect volunteers were en...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e31819afb5c

    authors: Sehi M,Pinzon-Plazas M,Feuer WJ,Greenfield DS

    更新日期:2009-10-01 00:00:00

  • Can frequency-doubling technology and short-wavelength automated perimetries detect visual field defects before standard automated perimetry in patients with preperimetric glaucoma?

    abstract:PURPOSE:To assess the ability of frequency-doubling technology (FDT) perimetry and short-wavelength automated perimetry (SWAP) to detect glaucomatous damage in preperimetric glaucoma subjects. PARTICIPANTS:Two hundred seventy-eight eyes of 278 subjects categorized as normal eyes [n=98; intraocular pressure <20 mm Hg, ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e31803bbb17

    authors: Ferreras A,Polo V,Larrosa JM,Pablo LE,Pajarin AB,Pueyo V,Honrubia FM

    更新日期:2007-06-01 00:00:00

  • Apolipoprotein E genotypes in pseudoexfoliation syndrome and pseudoexfoliation glaucoma.

    abstract:PURPOSE:Pseudoexfoliation (PEX) syndrome, an age-related, systemic, elastic microfibrillopathy, is characterized by fibrillar-granular deposits in the anterior segment of the eye. Although not representing a true amyloidosis, PEX syndrome shares some features with amyloid disorders, such as Alzheimer disease. It has be...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3181ca76c4

    authors: Krumbiegel M,Pasutto F,Mardin CY,Weisschuh N,Paoli D,Gramer E,Weber BH,Kruse FE,Schlötzer-Schrehardt U,Reis A

    更新日期:2010-10-01 00:00:00

  • Melatonin Levels in Patients With Primary Open-angle Glaucoma With High or Low Intraocular Pressure.

    abstract:PURPOSE:To evaluate circulatory melatonin levels by assessing nocturnal urinary excretion of 6-sulfatoxymelatonin (aMT6s) in patients with primary open-angle glaucoma (POAG) and to compare the high-tension group and the low-tension group. METHODS:This study included 80 eyes of 41 POAG patients and 87 eyes of 44 contro...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001130

    authors: Kim JY,Jeong AR,Chin HS,Kim NR

    更新日期:2019-02-01 00:00:00

  • Latanoprost-induced iris heterochromia and open-angle glaucoma: a clinicopathologic report.

    abstract:PURPOSE:To report the histopathologic and immunohistochemical findings from the iridectomy specimen of a patient with acquired unilateral iris heterochromia due to latanoprost. PATIENT AND METHODS:A 45-year-old woman with open-angle glaucoma and unilateral iris heterochromia was evaluated for uncontrolled intraocular ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/00061198-200110000-00009

    authors: Tsai JC,Sivak-Callcott JA,Haik BG,Zhang J,McLean IW

    更新日期:2001-10-01 00:00:00

  • Transscleral contact krypton laser cyclophotocoagulation for treatment of posttraumatic glaucoma.

    abstract:PURPOSE:To evaluate the usefulness of the krypton laser for transscleral contact cyclophotocoagulation in the treatment of posttraumatic glaucoma. PATIENTS AND METHODS:A total of 18 eyes of 18 patients with therapy-resistant posttraumatic glaucoma treated with krypton laser cyclophotocoagulation from 1991 to 1996 were...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/00061198-200104000-00002

    authors: Raivio VE,Immonen IJ,Laatikainen LT,Puska PM

    更新日期:2001-04-01 00:00:00

  • Corneal viscoelasticity differences between diabetic and nondiabetic glaucomatous patients.

    abstract:PURPOSE:To investigate corneal viscoelasticity in primary open-angle glaucoma patients with and without diabetes mellitus, and to correlate corneal hysteresis (CH) with central corneal thickness (CCT). METHODS:In this cross-sectional study, 44 primary open-angle glaucoma patients [19 with diabetes (34 eyes) and 25 wit...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3181b4caa1

    authors: Castro DP,Prata TS,Lima VC,Biteli LG,de Moraes CG,Paranhos A Jr

    更新日期:2010-06-01 00:00:00

  • Evaluation of macular thickness and peripapillary retinal nerve fiber layer thickness for detection of early glaucoma using spectral domain optical coherence tomography.

    abstract:PURPOSE:To evaluate the diagnostic ability of macular parameters and peripapillary retinal nerve fiber layer (RNFL) parameters for early glaucoma using spectral domain optical coherence tomography (SD-OCT). MATERIALS AND METHODS:One eye from 32 early glaucoma patients (including preperimetric glaucoma) and 32 normal p...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3181e079ed

    authors: Nakatani Y,Higashide T,Ohkubo S,Takeda H,Sugiyama K

    更新日期:2011-04-01 00:00:00

  • Delayed corneal epitheliopathy after antimetabolite-augmented trabeculectomy.

    abstract:PURPOSE:The authors describe the first case of delayed antimetabolite-related corneal epithelial toxicity after trabeculectomy and its successful treatment with limbal stem cell transplantation. METHODS:A 73-year-old woman underwent trabeculectomy with intraoperative mitomycin C. After surgery she received six 5-mg in...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:

    authors: Manche EE,Afshari MA,Singh K

    更新日期:1998-08-01 00:00:00

  • Aqueous vascular endothelial growth factor and endothelin-1 levels in branch retinal vein occlusion associated with normal tension glaucoma.

    abstract:PURPOSE:To evaluate aqueous levels of vascular endothelial growth factor (VEGF) and endothelin-1 (ET-1) in patients with branch retinal vein occlusion (BRVO) with and without normal tension glaucoma (NTG), and to assess the therapeutic efficacy of intravitreal bevacizumab (IVB) in these patients. METHODS:Sixteen eyes ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3182312047

    authors: Sin BH,Song BJ,Park SP

    更新日期:2013-02-01 00:00:00

  • Clinical Efficacy and Safety Outcomes of Micropulse Trans-Scleral Diode Cyclophotocoagulation in Patients with Advanced Glaucoma.

    abstract:PRECIS:Micropulse trans-scleral cyclophotocoagulation is only moderately effective in lowering intraocular pressure and useful as an adjunct procedure to other glaucoma surgeries. There was a small risk of loss of vision, prolonged hypotony and phthisis bulbi. AIMS:To determine the efficacy and safety of a single micr...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001729

    authors: Lim JYE,Cecilia AM,Lim KAD,Sng C,Loon SC,Lun WXK,Chew TKP,Koh TCV

    更新日期:2020-10-29 00:00:00