Abstract:
:Scanning laser ophthalmoscopy is capable of producing video fluorescein angiograms with high spatial and temporal resolution. Digital image analysis of these angiograms has been used to produce measures of capillary flow velocities in perimacular capillaries. We have recently utilized the same technique to measure flow velocities in the superficial capillary layers of the optic nerve head. We performed video fluorescein angiograms using the Ro-denstock (Germany) scanning laser ophthalmoscope. The passage of hyperflu-orescent particles through optic nerve head capillaries was imaged in five healthy subjects (two men and three women). The flow velocity for each of eight to 10 capillaries in each subject was measured three to five times. The mean capillary blood flow velocity for all subjects was 2.71 mm/s. These results are similar to those obtained in perifoveal capillaries. We have demonstrated that scanning laser fluorescein angiography can be adapted for measuring superficial optic disk capillary flow velocities. The possibility remains for the imaging of capillaries in deeper portions of the optic nerve head by using the confocol abilities of the scanning laser ophthalmoscope. Future use of this technique may aid our understanding of the pathophysiology of optic neuropathy.
journal_name
J Glaucomajournal_title
Journal of glaucomaauthors
Cantor LB,Harris A,Wolf S,Sponsel WE,Arend Osubject
Has Abstractpub_date
1994-07-01 00:00:00pages
S61-64eissn
1057-0829issn
1536-481Xpii
00061198-199400321-00008journal_volume
3 Suppl 1pub_type
杂志文章abstract:PURPOSE:To evaluate the neuroprotective effect of rasagiline (N-propargyl-1 (R)-aminoindan), a selective monoamine oxidase inhibitor, on the survival of retinal ganglion cells (RGCs) in glaucomatous rat eyes. Rasagiline is an FDA approved anti-Parkinson disease drug with neuroprotective capabilities that were shown in ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181e3d101
更新日期:2011-06-01 00:00:00
abstract::We report a case of acute angle closure with significantly elevated intraocular pressure 9 hours after implantation of a phakic intraocular lens for high myopia. ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001533
更新日期:2020-07-01 00:00:00
abstract:PURPOSE:This study was designed to evaluate the effect of microgravity on the diurnal variation of intraocular pressure (IOP). METHODS:IOPs were measured with the pressure phosphene tonometer in 1 subject (the first Korean astronaut) during spaceflight. IOPs were measured every 3 hours during day time (6 times per day...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181f464d2
更新日期:2011-10-01 00:00:00
abstract::A 54-year-old Indian male with a diagnosis of ocular hypertension was started on a prostaglandin analog (PGA) in both eyes to lower intraocular pressure. Six years later, he developed progressively increasing bilateral limbal conjunctival hyperpigmentation. Travoprost was discontinued and replaced with brinzolamide an...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000255
更新日期:2016-01-01 00:00:00
abstract::While working with a large data set of Goldmann applanation tonometry (GAT) intraocular pressure (IOP) measurements for a separate investigation, we observed that the IOP distribution favored even-numbered values. Study of this phenomenon has been limited, and this larger data set enabled inquiry that showed new insig...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001412
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:To determine the level of adherence to the American Academy of Ophthalmology preferred practice pattern (PPP) guidelines for quality primary open-angle glaucoma (POAG) and POAG suspect (POAGS) care among retail-based optometrists. METHODS:Patients with a diagnosis of POAG or POAGS who participated in a telemed...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001093
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:To assess the reproducibility of retinal nerve fiber layer thickness and macular thickness measurements using OCT-3. METHODS:Randomly chosen eyes of healthy individuals were scanned following pupillary dilation by two trained operators (RGO, RV) using OCT-3 (software version A1.1, Carl Zeiss Meditec, Inc., Dub...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/00061198-200406000-00012
更新日期:2004-06-01 00:00:00
abstract::The mainstay of open-angle glaucoma surgery involves subconjunctival drainage of aqueous fluid. Insertion of the XEN Gel Stent leads to formation of a subconjunctival bleb to assist in the drainage of aqueous fluid and offers the advantage of ease and speed of insertion with conjunctival sparing over traditional surgi...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001058
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:To assess the efficacy and safety of botulinum toxin type A (BoNT-A) injection in patients suffering from intractable periorbital pain after acute angle closure glaucoma (AACG). PATIENTS AND METHODS:In this prospective randomized intervention study, 19 patients suffering from periorbital pain after an AACG att...
journal_title:Journal of glaucoma
pub_type: 杂志文章,随机对照试验
doi:10.1097/IJG.0b013e3181ca76a9
更新日期:2010-10-01 00:00:00
abstract:PURPOSE:The mechanism by which the prostaglandin F2alpha-related antiglaucoma compound isopropyl unoprostone (referred to as unoprostone) reduces intraocular pressure is largely unknown. Another prostaglandin F2alpha-related compound, latanoprost, influences the activities of matrix metalloproteinases in ciliary muscle...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/00061198-200108000-00005
更新日期:2001-08-01 00:00:00
abstract:PURPOSE:To identify the distribution, variation, and determinants of ganglion cell-inner plexiform layer (GC-IPL) thickness in healthy Turkish children measured by high-definition optical coherence tomography (HD-OCT). PATIENTS AND METHODS:This institutional study involved 296 eyes from 296 healthy children aged betwe...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000168
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:The objective of this study is to evaluate capillary blood flow of the juxtapapillary retina and neuroretinal rim area in primary open angle glaucoma (POAG) by a new noninvasive method performing a high-definition topography of perfused vessels of the retina and the optic nerve head with simultaneous evaluation...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of selective laser trabeculoplasty (SLT) versus argon laser trabeculoplasty (ALT) in lowering the intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension secondary to pseudoexfoliation. DESIGN:Multicentered randomized clinical trial. PARTICIPANTS:A total...
journal_title:Journal of glaucoma
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/IJG.0b013e31829e55e4
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:To determine the risk factors for hyphema after trabeculectomy with mitomycin C (MMC). PATIENTS AND METHODS:In total, 420 patients (420 eyes) with glaucoma who underwent trabeculectomy with MMC between June 1, 2005 and December 31, 2010 at Kumamoto University Hospital, Japan, were retrospectively evaluated. Hy...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3182741c85
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:To evaluate tonometric outcomes of patients with primary angle closure glaucoma (PACG) who have undergone trabeculectomy with mitomycin C (MMC) with and without concurrent phacoemulsification and to identify risk factors for postoperative failure. PATIENTS AND METHODS:Retrospective cohort study of 44 eyes of 3...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000493
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To compare the accuracy of the "ISNT" rule [neural rim width of inferior(I)≥superior(S)≥nasal(N)≥temporal(T) regions] and the abbreviated variant, the "IS" rule (inferior≥superior regions) to differentiate normal from glaucomatous eyes. MATERIALS AND METHODS:Medical records of patients who were evaluated in 20...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000072
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:To study the relationship between optic disc hemorrhages and four different groups of medications used in general vascular disease and diabetes. METHODS:The authors screened citizens of the city of Malmö, Sweden who were between 57 and 79 years old (32,918 subjects), in order to find individuals with undetecte...
journal_title:Journal of glaucoma
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00061198-200206000-00011
更新日期:2002-06-01 00:00:00
abstract:PURPOSE:To evaluate the safety and efficacy of Ahmed Glaucoma Valve implantation (AGVI) for the management of neovascular glaucoma (NVG) associated with proliferative diabetic retinopathy (PDR) in the vitrectomized eyes. PATIENTS AND METHODS:We reviewed the medical records of patients with NVG associated with PDR who ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181f3eb06
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To assess the ability of frequency-doubling technology (FDT) perimetry and short-wavelength automated perimetry (SWAP) to detect glaucomatous damage in preperimetric glaucoma subjects. PARTICIPANTS:Two hundred seventy-eight eyes of 278 subjects categorized as normal eyes [n=98; intraocular pressure <20 mm Hg, ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31803bbb17
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:To determine the optimal OCT-3 scanning protocol. METHODS:Normal subjects, ocular hypertensive, and open-angle glaucoma patients were enrolled. The "fast" RNFL scan protocol consists of 3 consecutive circular scans, each containing 256 A-scans obtained in a single 1.92 second session. The "regular" RNFL scan p...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/00061198-200404000-00010
更新日期:2004-04-01 00:00:00
abstract:PURPOSE:To discuss a case in which melanocytoma of the ciliary body presented with widespread pigment dispersion and elevated intraocular pressure (IOP). METHODS:A 64-year old woman presented with increased IOP and persistent anterior segment inflammation in her right eye. She had undergone a trabeculectomy for uncont...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract:PURPOSE:To evaluate the reproducibility of retinal nerve fiber layer (RNFL) thickness measurements in normal and glaucoma patients using the spectral optical coherence tomography (OCT)/scanning laser ophthalmosope (SLO). METHODS:One experienced operator measured peripapillary RNFL thickness 3 times in succession in 98...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181ca7cbe
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the risk of developing glaucoma in patients taking systemic fluoroquinolones. METHODS:A case-control study was carried out among a cohort of subjects who had visited an ophthalmologist in the Province of British Columbia, Canada from 2000 to 2007. Cases were identified as those newly diagnosed wi...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31829463c1
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:To compare the efficacy, safety, and long-term results of intraocular pressure (IOP) reduction by diode laser contact cyclophotocoagulation (DCPC) and Ahmed glaucoma valve (AGV) implant in cases of neovascular glaucoma. METHODS:A total of 66 eyes of 66 patients with neovascular glaucoma were prospectively a...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31817d235c
更新日期:2009-03-01 00:00:00
abstract:PURPOSE:To investigate the effect of modern vaginal labor using epidural anesthesia on the intraocular pressure (IOP) and on the mean ocular perfusion pressure (MOPP) in healthy women. PATIENTS AND METHODS:In this prospective observational study, eligible candidates were healthy pregnant women for vaginal delivery wit...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000559
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:We present a case of persistent aqueous misdirection, after Ahmed glaucoma valve surgery, despite undergoing an anterior vitrectomy with hyaloido-zonulectomy and iridectomy. CASE REPORT:A 73-year-old female patient, 4 months after phacotrabeculectomy, was referred with persistent high intraocular pressure...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000877
更新日期:2018-04-01 00:00:00
abstract:PURPOSE:To evaluate the usefulness of the krypton laser for transscleral contact cyclophotocoagulation in the treatment of posttraumatic glaucoma. PATIENTS AND METHODS:A total of 18 eyes of 18 patients with therapy-resistant posttraumatic glaucoma treated with krypton laser cyclophotocoagulation from 1991 to 1996 were...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/00061198-200104000-00002
更新日期:2001-04-01 00:00:00
abstract:PURPOSE:To investigate the parasympathetic cardiovascular regulation, baroreflex sensitivity (BRS), and pulse wave velocity (PWV) in exfoliation syndrome (XFS). METHODS:Heart rate variability indices [standard deviation of all RR intervals (SDNN); the mean of absolute successive differences (RMSSD); the percentage of ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181379d67
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:Optic disc photographs of 750 patients attending a glaucoma practice were examined to identify focal peripapillary arteriolar narrowing. METHODS:A subgroup of 110 of these patients' photographs, who had also had finger circulation tested for vasospasm to cold, were divided into patients with peripapillary foca...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1996-02-01 00:00:00
abstract:PURPOSE:To investigate the effect of nepafenac on intraocular pressure (IOP) in primary open-angle glaucoma (POAG) patients treated with prostaglandin (PG) analogs. MATERIALS AND METHODS:This prospective clinical study included 35 patients who had been receiving latanoprost (n=12), travoprost (n=12), or bimatoprost (n...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000204
更新日期:2016-03-01 00:00:00