What is the role of noninvasive ventilation in cystic fibrosis?

Abstract:

PURPOSE OF REVIEW:The use of noninvasive ventilatory support in patients with cystic fibrosis (CF) has increased exponentially over the past 2 decades. This review examines the current knowledge and considers potential future directions for use of noninvasive ventilation in CF patients. RECENT FINDINGS:Noninvasive ventilation was originally reported as a bridge to transplantation in CF patients with severe respiratory failure but is now used as a long-term treatment modality for patients with respiratory failure independent of transplant status. In 2013 to 2014, over 400 publications on noninvasive ventilation demonstrate its increasing clinical application, however only seven reference CF. Recent technological advances and potential benefits to CF patients are considered. SUMMARY:The role of noninvasive ventilation in CF patients in chronic respiratory failure is established, but future prospective studies are needed to determine further indications and optimal timing of this intervention. Developments in both ventilator and interface design may enhance the efficacy of ventilation in CF patients but require careful individualized assessment and regular review. The implications on treatment burden and quality of life in CF also need to be studied.

journal_name

Curr Opin Pulm Med

authors

Bright-Thomas RJ,Johnson SC

doi

10.1097/MCP.0000000000000105

subject

Has Abstract

pub_date

2014-11-01 00:00:00

pages

618-22

issue

6

eissn

1070-5287

issn

1531-6971

journal_volume

20

pub_type

杂志文章,评审
  • Prognosis in cystic fibrosis.

    abstract::Prognosis for patients with cystic fibrosis has improved dramatically over the past three decades. In the United States, median survival age is now 28.9 years. Although genotype predicts exocrine pancreatic function, it does not correlate with pulmonary status or overall clinical outcome. However, there are a number o...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-199511000-00003

    authors: Rosenstein BJ,Zeitlin PL

    更新日期:1995-11-01 00:00:00

  • Risk factors and early outcomes of patients with symptomatic distal vs. proximal deep-vein thrombosis.

    abstract:PURPOSE OF REVIEW:Isolated distal deep-vein thrombosis (iDDVT) is a distal deep-vein thrombosis (DVT) without proximal DVT or pulmonary embolism. Although its clinical significance is uncertain, its prevalence is increasing with the use of whole leg compression ultrasonography. Epidemiological data giving reported rate...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e328349a9e3

    authors: Galanaud JP,Bosson JL,Quéré I

    更新日期:2011-09-01 00:00:00

  • Does gender matter: sex-specific aspects of symptoms, outcome, and therapy of obstructive sleep apnea.

    abstract:PURPOSE OF REVIEW:Obstructive sleep apnea (OSA) has historically been considered as a male disease. As a result, female individuals with OSA were often under-diagnosed and under-treated compared with male individuals. However, recent data suggest that several OSA-associated adverse cardiovascular outcomes are more pron...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章

    doi:10.1097/MCP.0000000000000728

    authors: Schiza SE,Bouloukaki I

    更新日期:2020-11-01 00:00:00

  • A question of time: systemic corticosteroids in managing acute asthma in children.

    abstract:PURPOSE OF REVIEW:The aim of this article is to examine the evidence for the effectiveness of systemic corticosteroids in managing acute asthma in children as it relates to the timing of its administration. RECENT FINDINGS:Three themes relevant to the timing of systemic corticosteroid administration as it relates to m...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e32835b590a

    authors: Bhogal SK

    更新日期:2013-01-01 00:00:00

  • Pleural effusions in hematologic malignancies and their management with indwelling pleural catheters.

    abstract:PURPOSE OF REVIEW:Pleural effusions in patients with hematologic malignancy may represent malignant pleural effusion (MPE) or occur secondary to infection, treatment effects, and other common causes. The impact of MPE on prognosis in this cohort remains unclear. Indwelling pleural catheters (IPCs) are routinely placed ...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000490

    authors: Vakil E,Jimenez CA,Faiz SA

    更新日期:2018-07-01 00:00:00

  • Macrolide and occult infection in asthma.

    abstract:PURPOSE OF REVIEW:A small percentage of asthma exacerbations are linked with infection by an atypical bacterium, such as Chlamydia pneumoniae or Mycoplasma pneumoniae. These bacteria also have been proposed to cause occult chronic lower airway inflammation and to initiate nonatopic asthma in adults. Consequently, the l...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-200401000-00003

    authors: Cazzola M,Matera MG,Blasi F

    更新日期:2004-01-01 00:00:00

  • Uncommon respiratory pathogens.

    abstract:PURPOSE OF REVIEW:In many cases, the specific pathogen responsible for a respiratory infection is not identified and can lead to improper medical treatment, increased duration of illness, and possibly contributes to the development of antibiotic resistance. Molecular-based diagnostic methodologies have significantly im...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.mcp.0000219274.65557.dc

    authors: Lednicky JA,Rayner JO

    更新日期:2006-05-01 00:00:00

  • Serologic evaluation in idiopathic interstitial pneumonias.

    abstract:PURPOSE OF REVIEW:Diagnosis of idiopathic interstitial pneumonias (IIPs) requires the exclusion of, among others, concomitant connective tissue diseases (CTDs), which may present as interstitial lung disease (ILD). This review focuses on the evaluation required to separate these entities through serology, although not ...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e3283560840

    authors: Papiris SA,Kagouridis K,Bouros D

    更新日期:2012-09-01 00:00:00

  • Medical thoracoscopy.

    abstract::Thoracoscopy has received increasing attention over the past decade as a result of the considerable advances that have been made in the development of endoscopic instruments. In contrast to the newly established video-assisted thoracoscopic surgery, the classic way to perform thoracoscopy is using only local anesthesi...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-199807000-00010

    authors: Loddenkemper R,Schönfeld N

    更新日期:1998-07-01 00:00:00

  • Pulmonary hypertension due to interstitial lung disease.

    abstract:PURPOSE OF REVIEW:Pulmonary hypertension has been reported to complicate the course of a number of fibrotic lung diseases, including idiopathic pulmonary fibrosis, chronic hypersensitivity pneumonitis and nonspecific interstitial pneumonitis. Most commonly, mild elevations in the mean pulmonary artery pressure are seen...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000599

    authors: King CS,Nathan SD

    更新日期:2019-09-01 00:00:00

  • Upper respiratory tract infections.

    abstract::In reviewing recent advances in upper respiratory tract infections, we focus on five key topics. First, the use of ribavirin in the treatment of respiratory syncytial virus infection has been limited to the immunosuppressed. Prophylaxis in high-risk patients with specific immunoglobulin is effective and a new monoclon...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-199905000-00006

    authors: Moore DA,Sharland M,Friedland JS

    更新日期:1999-05-01 00:00:00

  • Adenocarcinoma of the lung: current concepts in radiologic diagnosis and management.

    abstract:PURPOSE OF REVIEW:Since the introduction especially of multidetector computed tomography scanners, detection of peripheral pulmonary nodules as small as 2-3 mm is now a frequent event even in individuals without a significant smoking history. This preponderance of small indeterminate nodules has necessitated reconsider...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e3281c9b107

    authors: Shiau MC,Bonavita J,Naidich DP

    更新日期:2007-07-01 00:00:00

  • Common variable immunodeficiency-associated granulomatous and interstitial lung disease.

    abstract:PURPOSE OF REVIEW:Common variable immunodeficiency (CVID) is the most common primary immunodeficiency characterized by a deficiency of immunoglobulins. Approximately 30% of the patients develop autoimmune and granulomatous disease. Similar to sarcoidosis, granulomatous disease in CVID can potentially affect all organs,...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e3283642c47

    authors: Prasse A,Kayser G,Warnatz K

    更新日期:2013-09-01 00:00:00

  • Adult tuberculosis overview: African versus Western perspectives.

    abstract::Tuberculosis is currently an enormous global health problem. In industrialized countries in Western Europe and North America, tuberculosis case rates are low and an increasing proportion of cases now occur in foreign-born individuals and in marginalized populations, including the homeless, prisoners, drug users, and p...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-200005000-00003

    authors: Johnson JL,Ellner JJ

    更新日期:2000-05-01 00:00:00

  • Health-related quality of life in asthma.

    abstract::One aim of caring for adults and children with asthma should be the identification and treatment of the functional impairments that are troublesome to these patients in their daily lives. Studies have shown that correlations between measures of clinical asthma severity and control and health-related quality of life (H...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-199903000-00005

    authors: Juniper EF

    更新日期:1999-03-01 00:00:00

  • Insights about the economic impact of chronic obstructive pulmonary disease readmissions post implementation of the hospital readmission reduction program.

    abstract:PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) affects over 12 million adults in the United States and is the third leading cause of 30-day readmissions. COPD is costly with almost $50 billion in direct costs annually. Total COPD costs can be up to double the identified direct costs because of comorbid ...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000454

    authors: Press VG,Konetzka RT,White SR

    更新日期:2018-03-01 00:00:00

  • Emerging concepts in pleural infection.

    abstract:PURPOSE OF REVIEW:Pleural infection remains an important pulmonary disease, causing significant morbidity and mortality. There is a resurgence of disease burden despite introduction of antibiotics and pneumococcal vaccines. A revisit of the pathogenesis and update on intervention may improve the care of pleural infecti...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000487

    authors: Chan KP,Fitzgerald DB,Lee YCG

    更新日期:2018-07-01 00:00:00

  • Treatment options for patients with recurrent, symptomatic pleural effusions secondary to heart failure.

    abstract:PURPOSE OF REVIEW:Pleural effusions are a common finding in the nearly six million Americans diagnosed with heart failure. This review focuses on the historical, present and potential future trends in the management of such benign pleural effusions. RECENT FINDINGS:The management of symptomatic pleural effusions, in g...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000176

    authors: Freeman RK

    更新日期:2015-07-01 00:00:00

  • Biomarkers in asthma.

    abstract:PURPOSE OF REVIEW:The purpose of this review is to highlight seminal and current literature that informs our understanding of the clinical and investigative utility of biomarkers in asthma. Biomarkers derive from a variety of sources [bronchiolar lavage (BAL), sputum, exhaled breath, and blood], and have widely variant...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e32831de235

    authors: Murugan A,Prys-Picard C,Calhoun WJ

    更新日期:2009-01-01 00:00:00

  • Influenza update: vaccine development and clinical trials.

    abstract::Although influenza activity throughout the world has been relatively low during the past year, epidemics of influenza A, in particular, which are caused by new virus variants, continue to be a major public health problem. Widespread vaccination is the only rational measure that can be used for the prevention of illnes...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-200205000-00010

    authors: Wareing MD,Tannock GA

    更新日期:2002-05-01 00:00:00

  • Pneumonia due to methicillin-resistant Staphylococcus aureus: clinical features, diagnosis and management.

    abstract:PURPOSE OF REVIEW:The review highlights the clinical findings and the management of community-acquired, health-care associated and nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA). RECENT FINDINGS:Although previously considered as a purely nosocomial event, community-acquired MRSA pneumon...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e3283292666

    authors: Tacconelli E,De Angelis G

    更新日期:2009-05-01 00:00:00

  • Fixed-dose versus adjusted-dose low molecular weight heparin for the initial treatment of patients with deep venous thrombosis.

    abstract::Patients with acute deep vein thrombosis (DVT) were treated with a body-weight independent dosage of 2 x 8000 aXa IU low-molecular-weight heparin (LMWH) Certoparin. After the subcutaneous administration of 8000 IU Certoparin, pharmacodynamic parameters did not differ between patients and healthy volunteers, and the AU...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-200209000-00007

    authors: Harenberg J

    更新日期:2002-09-01 00:00:00

  • Prevalence and impact of depression in chronic obstructive pulmonary disease patients.

    abstract:PURPOSE OF REVIEW:This review presents recent advances in the study of the depression that is so often co-morbid with chronic obstructive pulmonary disease. The discussion includes prevalence, etiology, impact and management. RECENT FINDINGS:Efforts continue to find a reliable prevalence rate for co-morbid depression ...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.mcp.0000208450.50231.c6

    authors: Norwood R

    更新日期:2006-03-01 00:00:00

  • Cardiovascular consequences of obstructive sleep apnea in different study models and novel perspectives.

    abstract:PURPOSE OF REVIEW:Obstructive sleep apnea (OSA) is heterogeneous in terms of contributing pathophysiological mechanisms, clinical presentation, and consequences. Different study models from animal models of intermittent hypoxia over case-control, cohort, and population-based observational studies to uncontrolled interv...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章

    doi:10.1097/MCP.0000000000000618

    authors: Schwarz EI

    更新日期:2019-11-01 00:00:00

  • Unclassifiable interstitial lung disease: from phenotyping to possible treatments.

    abstract:PURPOSE OF REVIEW:Accurate diagnosis of interstitial lung diseases (ILDs) can be challenging, and a substantial percentage of ILD patients remain unclassifiable even after thorough assessment by an experienced multidisciplinary team. In this review, we summarize the recent literature on the definition, prevalence, diag...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000509

    authors: Guler SA,Ryerson CJ

    更新日期:2018-09-01 00:00:00

  • Normal volume and cellular contents of pleural fluid.

    abstract::The pleural space in healthy humans was thought to contain a few milliliters of fluid, based on extrapolation from animal studies. However, because of the obvious technical difficulties in atraumatically retrieving such a small volume of fluid, the exact volume and cellular content of human pleural fluid has not been ...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-200107000-00002

    authors: Noppen M

    更新日期:2001-07-01 00:00:00

  • Pneumococcal virulence factors in community-acquired pneumonia.

    abstract:PURPOSE OF REVIEW:This manuscript reviews the recent literature related to new developments in the understanding of existing and novel virulence factors of the pneumococcus that are of potential importance in the development of novel preventive and therapeutic strategies. RECENT FINDINGS:The pneumococcal capsule and p...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章

    doi:10.1097/MCP.0000000000000674

    authors: Feldman C,Anderson R

    更新日期:2020-05-01 00:00:00

  • Infectious lung complications in patients with HIV/AIDS.

    abstract:PURPOSE OF REVIEW:The aim of this article is to review recent observations in the area of infectious lung complications in individuals with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). Since the immunodeficiency was first characterized, it has been associated with enhanced susceptibilit...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.mcp.0000156992.53246.f8

    authors: Boyton RJ

    更新日期:2005-05-01 00:00:00

  • Alternative algorithms and devices in sleep apnoea diagnosis: what we know and what we expect.

    abstract:PURPOSE OF REVIEW:Diagnosis of sleep apnoea was performed in sleep laboratories with polysomnography. This requires a room with supervision and presence of technologists and trained sleep experts. Today, clinical guidelines in most countries recommend home sleep apnoea testing with simple systems using six signals only...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章

    doi:10.1097/MCP.0000000000000726

    authors: Penzel T,Fietze I,Glos M

    更新日期:2020-11-01 00:00:00

  • Identification and management of pleural effusions of multiple aetiologies.

    abstract:PURPOSE OF REVIEW:Historically, pleural effusions have been attributed to a single cause. There is growing recognition that a substantial proportion of pleural effusions may have more than one underlying cause. The purpose of this review is to summarise recent findings regarding the diagnosis and treatment of effusions...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000388

    authors: Walker S,Maskell N

    更新日期:2017-07-01 00:00:00