Emerging concepts in pleural infection.

abstract：PURPOSE OF REVIEW:There is growing evidence that genetics plays a role in the development of chronic obstructive pulmonary disease. This review deals with the most recent findings, new methods to detect genetic susceptibility that may be helpful in this field, and how the environment may act on the genetic code of susc...

journal_title：Current opinion in pulmonary medicine

authors： Molfino NA

更新日期：2007-03-01 00:00:00

abstract：:Considerable progress has been made over the past 2 decades in defining and measuring health-related quality of life (QOL), and there is a growing recognition that these measures provide unique information about the impact of a chronic illness and its treatment. For patients with cystic fibrosis (CF), health-related Q...

journal_title：Current opinion in pulmonary medicine

authors： Quittner AL

更新日期：1998-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Coal mine workers are at risk for a range of chronic respiratory diseases including coal workers' pneumoconiosis, diffuse dust-related fibrosis, and chronic obstructive pulmonary disease. The purpose of this review is to describe coal mining processes and associated exposures to inform the diagnostic ...

journal_title：Current opinion in pulmonary medicine

authors： Go LH,Krefft SD,Cohen RA,Rose CS

更新日期：2016-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This review looks at what is currently known about liver disease in cystic fibrosis (CF) in light of the literature over the past year, and what the ongoing challenges are from a clinical and research perspective for the optimal management of cystic fibrosis liver disease (CFLD). RECENT FINDINGS:Pati...

journal_title：Current opinion in pulmonary medicine

authors： Rowland M,Bourke B

更新日期：2011-11-01 00:00:00

abstract：:Chest tubes and their accompanying pleural drainage units continue to present challenging questions regarding their optimal use. Appropriate chest tube size selection to accommodate the clinical situation is key, especially in the setting of large pleural air leaks lest a tension pneumothorax ensue. Connection of an a...

journal_title：Current opinion in pulmonary medicine

authors： Baumann MH

更新日期：2003-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Matrix metalloproteinases (MMPs) are a family of over 20 zinc-dependent proteases with different biological and pathological activities, and many have been implicated in several diseases. Although nonselective MMP inhibitors are known to induce serious side-effects, targeting individual MMPs may offer...

journal_title：Current opinion in pulmonary medicine

authors： Abd-Elaziz K,Jesenak M,Vasakova M,Diamant Z

更新日期：2021-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Glucocorticosteroids (GCSs) remain the cornerstone of therapy for treating the inflammatory component of asthma. Clinical response to GCS is heterogeneous, varying both within asthma 'endotypes', as well as the same individual. Different factors and micro-environment can alter the canonical GCS-induce...

journal_title：Current opinion in pulmonary medicine

authors： Mukherjee M,Svenningsen S,Nair P

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine recent reports of serosal involvement in sarcoidosis. RECENT FINDINGS:Peritoneal sarcoidosis continues to be a rare manifestation of the disease. Patients with peritoneal disease tend to be women between the ages of 20 and 40 years, and most commonly present with ascites and abdominal pain...

journal_title：Current opinion in pulmonary medicine

authors： Iyer S,Afshar K,Sharma OP

更新日期：2008-09-01 00:00:00

abstract：PURPOSE OF REVIEW:After the disappointing results of lung cancer screening trials conducted in the 1960s to the 1980s, a renewed interest in lung cancer screening emerged in the 1990s with the development of new technologies such as low-dose spiral CT. The literature regarding screening with biomarkers and CT continues...

journal_title：Current opinion in pulmonary medicine

authors： Manser R

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Adherence to asthma therapies is poor leading to unnecessary morbidity and increased use of emergency and hospital resources. Strategies to improve adherence have not been successful. RECENT FINDINGS:Asthma adherence disease management is a clinical method to improve adherence for asthma patients. Th...

journal_title：Current opinion in pulmonary medicine

authors： Weinstein AG

更新日期：2015-01-01 00:00:00

abstract：:Bronchial carcinoids and hamartomas are, respectively, the most common malignant and benign unusual primary lung neoplasms. These tumors are often asymptomatic but can cause central airway obstruction. Helical computed tomographic and radionuclide scintigraphic advances in their detection and evolution, together with ...

journal_title：Current opinion in pulmonary medicine

authors： Chan AL,Shelton DK,Yoneda KY

更新日期：2001-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Respiratory tract infections are a common reason for prescribing antibiotics, although not all of these infections require such therapy. Rapid diagnosis of etiology using point-of-care tests is a potentially useful way of reducing prescriptions of both unnecessary and unnecessarily broad-spectrum anti...

journal_title：Current opinion in pulmonary medicine

authors： Charles PG

更新日期：2008-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Malignant central airway obstruction heavily impacts patients' quality of life and its management continues to be a challenge. The current article will review the use of airway stents in this population. RECENT FINDINGS:Airway stenting is highly effective in palliating symptoms of airway obstruction....

journal_title：Current opinion in pulmonary medicine

authors： Casal RF

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:A relatively new class of CD4 expressing T cells that also express and release interleukin-17 (Th17 cells) is gaining attention based on their capacity to regulate inflammatory responses in a spectrum of chronic autoimmune diseases. The purpose of this review is to consider recent studies relating to ...

journal_title：Current opinion in pulmonary medicine

authors： Crouser ED

更新日期：2018-09-01 00:00:00

abstract：:There have been a large number of randomized trials comparing standard unfractionated intravenous heparin with low-molecular-weight heparin for the treatment of deep-vein thrombosis, but only two of these have looked at outpatient therapy. There have been only two randomized trials including patients with symptomatic ...

journal_title：Current opinion in pulmonary medicine

authors： Wells PS

更新日期：2001-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) is one of the most prevalent and increasing health problems in the elderly on a worldwide scale. The management of COPD in older patients presents practical diagnostic and treatment issues, which are reviewed with reference to the stable stage of the diseas...

journal_title：Current opinion in pulmonary medicine

authors： Pistelli R,Ferrara L,Misuraca C,Bustacchini S

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Dornase alfa (Pulmozyme) is one of the most commonly used medications to treat the lung disease of cystic fibrosis (CF). As other respiratory medications have entered the clinical market, understanding the proper use and indication for dornase alfa is increasingly important. In addition, dornase alfa ...

journal_title：Current opinion in pulmonary medicine

authors： Wagener JS,Kupfer O

更新日期：2012-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Survival for patients with cystic fibrosis (CF) continues to improve. The proportion of CF patients over the age of 18 years is nearly 50%, and care providers will need to better understand this patient population. Despite these improvements, young females continue to have a worse prognosis and lower ...

journal_title：Current opinion in pulmonary medicine

authors： McIntyre K

更新日期：2013-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The catastrophic collapse of the World Trade Center (WTC) towers on September 11, 2001 created a large-scale disaster site in a densely populated urban environment. Over the ensuing months, tens of thousands of rescue, recovery and cleanup workers, volunteers, and residents of the adjacent community w...

journal_title：Current opinion in pulmonary medicine

authors： Banauch GI,Dhala A,Prezant DJ

更新日期：2005-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This review presents recent advances in the study of the depression that is so often co-morbid with chronic obstructive pulmonary disease. The discussion includes prevalence, etiology, impact and management. RECENT FINDINGS:Efforts continue to find a reliable prevalence rate for co-morbid depression ...

journal_title：Current opinion in pulmonary medicine

authors： Norwood R

更新日期：2006-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Spontaneous hemopneumothorax can be life threatening, and is a cause of patients presenting with unexplained signs of significant hypovolemia. The debate relating to patient selection and timing of surgery in patients with spontaneous hemopneumothorax remains unresolved. RECENT FINDINGS:Our experienc...

journal_title：Current opinion in pulmonary medicine

authors： Ng CSh,Yim AP

更新日期：2006-07-01 00:00:00

abstract：:Some time ago, the Th2 cytokine, interleukin (IL)-13, was identified as a critical regulator of the allergic response. Initial studies in animal models of disease provided compelling evidence that IL-13, independent from other Th2 cytokines, was necessary and sufficient to induce all features of allergic asthma. This ...

journal_title：Current opinion in pulmonary medicine

authors： Wills-Karp M,Chiaramonte M

更新日期：2003-01-01 00:00:00

abstract：:Disorders of sleep in children are distinctly different from sleep disorders in adults. Since children are forced to constantly learn and adapt, the effects of disordered sleep may be more profound. This paper reviews the disorders of sleep that are most significant in each of the stages of development from infancy to...

journal_title：Current opinion in pulmonary medicine

authors： Anstead M

更新日期：2000-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) and lung cancer are the leading causes of morbidity and mortality worldwide. The current research is focused on identifying the common and disparate events involved in epigenetic modifications that concurrently occur during the pathogenesis of COPD and lung...

journal_title：Current opinion in pulmonary medicine

authors： Sundar IK,Mullapudi N,Yao H,Spivack SD,Rahman I

更新日期：2011-07-01 00:00:00

abstract：:Prognosis for patients with cystic fibrosis has improved dramatically over the past three decades. In the United States, median survival age is now 28.9 years. Although genotype predicts exocrine pancreatic function, it does not correlate with pulmonary status or overall clinical outcome. However, there are a number o...

journal_title：Current opinion in pulmonary medicine

authors： Rosenstein BJ,Zeitlin PL

更新日期：1995-11-01 00:00:00

abstract：:Pulmonary embolism occurs in more than 175,000 patients each year in the United States. The objectives of treatment are to prevent death from the existing embolus, to prevent death and morbidity from recurrent pulmonary embolism, and to prevent morbidity from recurrent deep-vein thrombosis. For patients with adequate ...

journal_title：Current opinion in pulmonary medicine

authors： Raskob GE

更新日期：1999-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma outcomes constitute the cornerstone of asthma clinical research. Despite their known importance, it has been difficult for researchers to standardize these outcomes in large part because of the heterogeneity of the disease. This review seeks to provide an overview of recent recommendations for ...

journal_title：Current opinion in pulmonary medicine

authors： Parulekar AD,Alobaidy A,Hanania NA

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Severe asthma is a heterogeneous syndrome, encompassing several distinct clinical phenotypes. Different molecular and cellular pathways or endotypes determine the type of underlying airway inflammation in patients with severe asthma, which can be categorized as eosinophilic asthma (allergic and nonall...

journal_title：Current opinion in pulmonary medicine

authors： Brusselle GG,Joos G

更新日期：2014-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Regions of the neocortex most strongly activated during waking exhibit increased sleep intensity during subsequent sleep. The novel concept that aspects of sleep homeostasis are determined locally in the cortex contrasts with the established views that global changes in neocortical activity during sle...

journal_title：Current opinion in pulmonary medicine

authors： Szymusiak R

更新日期：2010-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights recent developments in liver disease associated with cystic fibrosis. RECENT FINDINGS:The broad spectrum of hepatobiliary problems in cystic fibrosis includes specific alterations ascribable to the underlying defect as well as lesions of iatrogenic origin or that reflect the ef...

journal_title：Current opinion in pulmonary medicine

authors： Colombo C

更新日期：2007-11-01 00:00:00