Prognosis in cystic fibrosis.

abstract：PURPOSE OF REVIEW:Asthma is a chronic inflammatory disease in which changes in macrophage polarization have been shown to contribute to the pathogenesis. The present review discusses the contribution of changes in macrophage function to asthma related to polarization changes and elaborates on possible therapeutic strat...

journal_title：Current opinion in pulmonary medicine

authors： van der Veen TA,de Groot LES,Melgert BN

更新日期：2020-01-01 00:00:00

abstract：:The neurotrophins are a family of peptides that promote survival, growth, and differentiation of neurons. Neurotrophins may also influence the function of nonneuronal cell types, including immune cells. The development and maintenance of asthma is thought to involve the nervous system and the immune system, but the ro...

journal_title：Current opinion in pulmonary medicine

authors： Carr MJ,Hunter DD,Undem BJ

更新日期：2001-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize recent studies that have quantified the incidence of death due to late thromboembolic disease among patients initially diagnosed with acute unprovoked pulmonary embolism. These findings will aid clinicians who must weigh the risk versus the benefits of long-term anticoagulant therapy. RE...

journal_title：Current opinion in pulmonary medicine

authors： White RH,Murin S

更新日期：2009-09-01 00:00:00

abstract：:There has been increased recognition of the importance of inflammatory cells and their products in the pathogenesis of asthma. From this recognition has evolved a number of new approaches to treat the various components of the asthmatic inflammatory response. Nonselective anti-inflammatory agents such as cyclosporine ...

journal_title：Current opinion in pulmonary medicine

authors： Floreani AA,Rennard SI

更新日期：1997-01-01 00:00:00

abstract：:Diabetes is a common complication of cystic fibrosis. Because it is associated with increased morbidity and mortality, prompt diagnosis and aggressive management of cystic fibrosis-related diabetes is important. The Cystic Fibrosis Foundation held a consensus conference in 1998 to define the standards of care for pati...

journal_title：Current opinion in pulmonary medicine

authors： Riggs AC,Seaquist ER,Moran A

更新日期：1999-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Obstructive sleep apnea (OSA) has historically been considered as a male disease. As a result, female individuals with OSA were often under-diagnosed and under-treated compared with male individuals. However, recent data suggest that several OSA-associated adverse cardiovascular outcomes are more pron...

journal_title：Current opinion in pulmonary medicine

authors： Schiza SE,Bouloukaki I

更新日期：2020-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The use of noninvasive ventilatory support in patients with cystic fibrosis (CF) has increased exponentially over the past 2 decades. This review examines the current knowledge and considers potential future directions for use of noninvasive ventilation in CF patients. RECENT FINDINGS:Noninvasive ven...

journal_title：Current opinion in pulmonary medicine

authors： Bright-Thomas RJ,Johnson SC

更新日期：2014-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Pulmonary hypertension has been reported to complicate the course of a number of fibrotic lung diseases, including idiopathic pulmonary fibrosis, chronic hypersensitivity pneumonitis and nonspecific interstitial pneumonitis. Most commonly, mild elevations in the mean pulmonary artery pressure are seen...

journal_title：Current opinion in pulmonary medicine

authors： King CS,Nathan SD

更新日期：2019-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize recent advances in our understanding of the impact sleep disturbances have on our health, with particular focus on the brain. The present review considers the influence of sleep disturbance on the neurovascular unit; the role of sleep disturbance in neurodege...

journal_title：Current opinion in pulmonary medicine

authors： Aguirre CC

更新日期：2016-11-01 00:00:00

abstract：PURPOSE OF REVIEW:In many cases, the specific pathogen responsible for a respiratory infection is not identified and can lead to improper medical treatment, increased duration of illness, and possibly contributes to the development of antibiotic resistance. Molecular-based diagnostic methodologies have significantly im...

journal_title：Current opinion in pulmonary medicine

authors： Lednicky JA,Rayner JO

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Matrix metalloproteinases (MMPs) are a family of over 20 zinc-dependent proteases with different biological and pathological activities, and many have been implicated in several diseases. Although nonselective MMP inhibitors are known to induce serious side-effects, targeting individual MMPs may offer...

journal_title：Current opinion in pulmonary medicine

authors： Abd-Elaziz K,Jesenak M,Vasakova M,Diamant Z

更新日期：2021-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The chronic lung diseases, asthma and chronic obstructive pulmonary disease, are pulmonary disorders in which persistent inflammation and alterations in lung structure contribute to a progressive loss of lung function. Although the exact type of inflammation and damage in each disease is distinct, the...

journal_title：Current opinion in pulmonary medicine

authors： Mohsenin A,Blackburn MR

更新日期：2006-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim is to summarize the evidence base for tuberculosis (TB) diagnostics, review recent policies on TB diagnostics, and discuss issues such as how evidence is translated into policy, limitations of the existing evidence base, and challenges involved in translating policies into impact. RECENT FIND...

journal_title：Current opinion in pulmonary medicine

authors： Pai M,Minion J,Steingart K,Ramsay A

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss pros and cons of anticoagulant treatment in the presence of symptomatic distal deep vein thrombosis. RECENT FINDINGS:Available data are responsible for a lack of consensus regarding treatment of distal deep vein thrombosis. SUMMARY:One standard diagnostic approach of suspected deep vein t...

journal_title：Current opinion in pulmonary medicine

authors： Righini M,Bounameaux H

更新日期：2008-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Smoking is a major risk factor for lung cancer, which is the leading cause of cancer-related deaths both in the USA and worldwide. Chronic obstructive pulmonary disease and emphysema are comorbid conditions often found in lung cancer patients. The inflammatory pathways that link chronic obstructive pu...

journal_title：Current opinion in pulmonary medicine

authors： Lee G,Walser TC,Dubinett SM

更新日期：2009-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Spontaneous hemopneumothorax can be life threatening, and is a cause of patients presenting with unexplained signs of significant hypovolemia. The debate relating to patient selection and timing of surgery in patients with spontaneous hemopneumothorax remains unresolved. RECENT FINDINGS:Our experienc...

journal_title：Current opinion in pulmonary medicine

authors： Ng CSh,Yim AP

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The catastrophic collapse of the World Trade Center (WTC) towers on September 11, 2001 created a large-scale disaster site in a densely populated urban environment. Over the ensuing months, tens of thousands of rescue, recovery and cleanup workers, volunteers, and residents of the adjacent community w...

journal_title：Current opinion in pulmonary medicine

authors： Banauch GI,Dhala A,Prezant DJ

更新日期：2005-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Exacerbations of asthma in children are most frequently precipitated by respiratory infections with a seasonal pattern. However, management takes little account of the underlying infective or other precipitant abnormality. RECENT FINDINGS:Interactions between environmental triggers, the airway microb...

journal_title：Current opinion in pulmonary medicine

authors： Cook J,Saglani S

更新日期：2016-01-01 00:00:00

abstract：:The nontuberculous mycobacteria (NTM), especially Mycobacterium avium complex, are being recognized with increasing frequency as clinical pathogens, not only as a cause of disseminated disease in patients with AIDS but also as a cause of chronic lung disease in patients without AIDS. These infections have traditionall...

journal_title：Current opinion in pulmonary medicine

authors： Griffith DE

更新日期：1997-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This article aims to review the most recent proteomic findings in tissue and biological fluids and application of new technologies for the study of interstitial lung diseases. RECENT FINDINGS:New insights into lung cell biology as well as novel pathogenetic pathways of different interstitial lung dis...

journal_title：Current opinion in pulmonary medicine

authors： Rottoli P,Bargagli E,Landi C,Magi B

更新日期：2009-09-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, we describe the 'state-of-the-art' in our knowledge of asthma and what gaps exist, which can be exploited in the future for effective translation of our knowledge from the bench or population studies to diagnosis and therapy. RECENT FINDINGS:The advent of microbiome research has expan...

journal_title：Current opinion in pulmonary medicine

authors： Brar T,Nagaraj S,Mohapatra S

更新日期：2012-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This article aims to review the geological background of environmental asbestos exposure and the distribution of asbestos-related disease (ARD) in association with naturally occurring asbestos (NOA), and discusses the potential health risks associated with exposure to non-occupational asbestos. RECEN...

journal_title：Current opinion in pulmonary medicine

authors： Bayram M,Bakan ND

更新日期：2014-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) and lung cancer are the leading causes of morbidity and mortality worldwide. The current research is focused on identifying the common and disparate events involved in epigenetic modifications that concurrently occur during the pathogenesis of COPD and lung...

journal_title：Current opinion in pulmonary medicine

authors： Sundar IK,Mullapudi N,Yao H,Spivack SD,Rahman I

更新日期：2011-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Idiopathic pulmonary fibrosis (IPF) is a progressive, invariably fatal condition with a median survival from diagnosis of only 3 years. Despite improvements in disease understanding, challenges remain in establishing a diagnosis and predicting prognosis in individual patients. Furthermore, limited und...

journal_title：Current opinion in pulmonary medicine

authors： Maher TM

更新日期：2013-09-01 00:00:00

abstract：:Chest tubes and their accompanying pleural drainage units continue to present challenging questions regarding their optimal use. Appropriate chest tube size selection to accommodate the clinical situation is key, especially in the setting of large pleural air leaks lest a tension pneumothorax ensue. Connection of an a...

journal_title：Current opinion in pulmonary medicine

authors： Baumann MH

更新日期：2003-07-01 00:00:00

abstract：PURPOSE OF REVIEW:In the past few years, there have been exciting developments in bronchoscopic efforts at attaining lung volume reduction (LVR), given real and perceived risks of surgical LVR. The purpose of this review is to discuss these techniques, with special emphasis on what we have learnt in the past 1-2 years....

journal_title：Current opinion in pulmonary medicine

authors： Taneja A

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the current understanding and clinical applicability of severity scoring systems in pneumonia management. RECENT FINDINGS:Severity scores in community-acquired pneumonia are strong markers of mortality, but are not necessarily clinical decision-aid tools. The use of severity scores to sup...

journal_title：Current opinion in pulmonary medicine

authors： Ranzani OT,Taniguchi LU,Torres A

更新日期：2018-05-01 00:00:00

abstract：PURPOSE OF REVIEW:A small percentage of asthma exacerbations are linked with infection by an atypical bacterium, such as Chlamydia pneumoniae or Mycoplasma pneumoniae. These bacteria also have been proposed to cause occult chronic lower airway inflammation and to initiate nonatopic asthma in adults. Consequently, the l...

journal_title：Current opinion in pulmonary medicine

authors： Cazzola M,Matera MG,Blasi F

更新日期：2004-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Accurate diagnosis of interstitial lung diseases (ILDs) can be challenging, and a substantial percentage of ILD patients remain unclassifiable even after thorough assessment by an experienced multidisciplinary team. In this review, we summarize the recent literature on the definition, prevalence, diag...

journal_title：Current opinion in pulmonary medicine

authors： Guler SA,Ryerson CJ

更新日期：2018-09-01 00:00:00

abstract：:Pulmonary embolism occurs in more than 175,000 patients each year in the United States. The objectives of treatment are to prevent death from the existing embolus, to prevent death and morbidity from recurrent pulmonary embolism, and to prevent morbidity from recurrent deep-vein thrombosis. For patients with adequate ...

journal_title：Current opinion in pulmonary medicine

authors： Raskob GE

更新日期：1999-07-01 00:00:00