Environmental exposure to asbestos: from geology to mesothelioma.

abstract：:Some time ago, the Th2 cytokine, interleukin (IL)-13, was identified as a critical regulator of the allergic response. Initial studies in animal models of disease provided compelling evidence that IL-13, independent from other Th2 cytokines, was necessary and sufficient to induce all features of allergic asthma. This ...

journal_title：Current opinion in pulmonary medicine

authors： Wills-Karp M,Chiaramonte M

更新日期：2003-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Sarcoidosis is a granulomatous systemic disease of unknown cause where the lung is the most frequently affected organ. Therapeutic management of the disease is challenging as clinical presentation and prognosis are very heterogeneous. In the present review, we will summarize the main advances in sarco...

journal_title：Current opinion in pulmonary medicine

authors： Sellarés J,Francesqui J,Llabres M,Hernandez-Gonzalez F,Baughman RP

更新日期：2020-09-01 00:00:00

abstract：:A gamma-scintigraphic study was carried out in 13 healthy individuals to compare the lung deposition of budesonide from a novel multidose dry powder inhaler (MDPI; Novolizer) with that from the Pulmicort Turbuhaler, and to assess the degree of flow rate dependence of the Novolizer. Median whole lung depositions for th...

journal_title：Current opinion in pulmonary medicine

authors： Newman SP,Hirst PH,Pitcairn GR

更新日期：2001-04-01 00:00:00

abstract：:Chest tubes and their accompanying pleural drainage units continue to present challenging questions regarding their optimal use. Appropriate chest tube size selection to accommodate the clinical situation is key, especially in the setting of large pleural air leaks lest a tension pneumothorax ensue. Connection of an a...

journal_title：Current opinion in pulmonary medicine

authors： Baumann MH

更新日期：2003-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews current data on pathophysiologic mechanisms by which sleep-disordered breathing during pregnancy may cause harm, and explores biological pathways for associated adverse maternal and fetal outcomes, especially pregnancy-induced hypertension and gestational diabetes. RECENT FINDING...

journal_title：Current opinion in pulmonary medicine

authors： Izci-Balserak B,Pien GW

更新日期：2010-11-01 00:00:00

abstract：:Intrathoracic neoplasms other than bronchogenic carcinoma comprise a disparate group of tumors that have in common an anatomic location within the thorax. For the purposes of this review, they are divided into three categories: pulmonary metastases from locations other than the thorax, mediastinal neoplasms, and unusu...

journal_title：Current opinion in pulmonary medicine

authors： Yoneda KY,Tharratt RS

更新日期：1997-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Poor adherence to asthma controller medications, particularly inhaled corticosteroids, has been well known for decades and is a major cause of uncontrolled asthma and increased healthcare utilization. This review presents recent evidence on factors leading to nonadherence in specific age groups, paren...

journal_title：Current opinion in pulmonary medicine

authors： Blake KV

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) is caused by a mixture of small airway disease (obstructive bronchitis) and parenchymal lung tissue destruction (emphysema). The relative contributions of these two pathologic states vary from person to person. Having the ability to phenotype patients into ...

journal_title：Current opinion in pulmonary medicine

authors： Stewart JI,Criner GJ

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Common variable immunodeficiency (CVID) is the most common primary immunodeficiency characterized by a deficiency of immunoglobulins. Approximately 30% of the patients develop autoimmune and granulomatous disease. Similar to sarcoidosis, granulomatous disease in CVID can potentially affect all organs,...

journal_title：Current opinion in pulmonary medicine

authors： Prasse A,Kayser G,Warnatz K

更新日期：2013-09-01 00:00:00

abstract：:Acute bronchitis in previously fit individuals is a common condition that is usually mild and self limiting. Chronic bronchitis remains a common cause of morbidity and mortality, and the cost to the nation due to lost working days and to health services is enormous. Cigarette smoking is the major etiologic factor, alt...

journal_title：Current opinion in pulmonary medicine

authors： Wilson R,Rayner CF

更新日期：1995-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Malignant pleural effusion (MPE) poses a common and significant clinical problem. Its pathogenesis is poorly understood and therapeutic options are limited. Herein are summarized animal models of MPE and their contributions in unveiling new aspects of the pathobiology of the condition. RECENT FINDING...

journal_title：Current opinion in pulmonary medicine

authors： Stathopoulos GT,Kalomenidis I

更新日期：2009-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To review and compare the constellations of causes and consequences of the two current pandemics, Covid-19 and climate change. RECENT FINDINGS:There has been a transient counterbalancing, in which the response to Covid-19 has briefly mitigated pollution and greenhouse gasses. This divergence belies m...

journal_title：Current opinion in pulmonary medicine

authors： Joshi M,Caceres J,Ko S,Epps SM,Bartter T

更新日期：2021-03-01 00:00:00

abstract：:Corticosteroids were the mainstay of therapy for idiopathic pulmonary fibrosis (IPF) for more than four decades, but their efficacy is unproven and toxicities are substantial. The course of IPF is characterized by progressive respiratory insufficiency, leading to death within 3 to 8 years from the onset of symptoms. A...

journal_title：Current opinion in pulmonary medicine

authors： Lynch JP 3rd,White E,Flaherty K

更新日期：2001-09-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, we highlight some of the developments achieved over the past 2 years in the field of novel antimicrobial compounds. RECENT FINDINGS:Modification of existing compound classes to create more powerful compounds capable of overcoming pathogen resistance and the introduction of completely ...

journal_title：Current opinion in pulmonary medicine

authors： Blasi F,Tarsia P,Cosentini R,Valenti V

更新日期：2004-05-01 00:00:00

abstract：:Patients with acute deep vein thrombosis (DVT) were treated with a body-weight independent dosage of 2 x 8000 aXa IU low-molecular-weight heparin (LMWH) Certoparin. After the subcutaneous administration of 8000 IU Certoparin, pharmacodynamic parameters did not differ between patients and healthy volunteers, and the AU...

journal_title：Current opinion in pulmonary medicine

authors： Harenberg J

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize recent studies that have quantified the incidence of death due to late thromboembolic disease among patients initially diagnosed with acute unprovoked pulmonary embolism. These findings will aid clinicians who must weigh the risk versus the benefits of long-term anticoagulant therapy. RE...

journal_title：Current opinion in pulmonary medicine

authors： White RH,Murin S

更新日期：2009-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Malignant central airway obstruction heavily impacts patients' quality of life and its management continues to be a challenge. The current article will review the use of airway stents in this population. RECENT FINDINGS:Airway stenting is highly effective in palliating symptoms of airway obstruction....

journal_title：Current opinion in pulmonary medicine

authors： Casal RF

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to highlight seminal and current literature that informs our understanding of the clinical and investigative utility of biomarkers in asthma. Biomarkers derive from a variety of sources [bronchiolar lavage (BAL), sputum, exhaled breath, and blood], and have widely variant...

journal_title：Current opinion in pulmonary medicine

authors： Murugan A,Prys-Picard C,Calhoun WJ

更新日期：2009-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Pulmonary cystic echinococcosis, a zoonosis caused by the larvae of the dog tapeworm Echinococcus granulosus, is considered as a major public health problem in countries where dogs are used to care for large herds. Despite its frequency and widespread endemicity, the literature on pulmonary cystic ech...

journal_title：Current opinion in pulmonary medicine

authors： Santivanez S,Garcia HH

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The use of noninvasive ventilatory support in patients with cystic fibrosis (CF) has increased exponentially over the past 2 decades. This review examines the current knowledge and considers potential future directions for use of noninvasive ventilation in CF patients. RECENT FINDINGS:Noninvasive ven...

journal_title：Current opinion in pulmonary medicine

authors： Bright-Thomas RJ,Johnson SC

更新日期：2014-11-01 00:00:00

abstract：:There has been increased recognition of the importance of inflammatory cells and their products in the pathogenesis of asthma. From this recognition has evolved a number of new approaches to treat the various components of the asthmatic inflammatory response. Nonselective anti-inflammatory agents such as cyclosporine ...

journal_title：Current opinion in pulmonary medicine

authors： Floreani AA,Rennard SI

更新日期：1997-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Pleural effusions in patients with hematologic malignancy may represent malignant pleural effusion (MPE) or occur secondary to infection, treatment effects, and other common causes. The impact of MPE on prognosis in this cohort remains unclear. Indwelling pleural catheters (IPCs) are routinely placed ...

journal_title：Current opinion in pulmonary medicine

authors： Vakil E,Jimenez CA,Faiz SA

更新日期：2018-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The Sleep Heart Health Study began in 1994 as a prospective cohort study of cardiovascular disease. The results of longitudinal analysis are not yet available, but numerous analyses of cross-sectional data have been published. This review provides an overview of study results so far. RECENT FINDINGS:...

journal_title：Current opinion in pulmonary medicine

authors： Gottlieb DJ

更新日期：2008-11-01 00:00:00

abstract：:Recently, with radiology some advances have been made in the care of patients with interstitial lung disease, predominately through the use of high-resolution computed tomography. This technique is helpful not only in the diagnosis of interstitial lung disease, but also in patient follow-up and management. Other techn...

journal_title：Current opinion in pulmonary medicine

authors： Wilcox AG

更新日期：1999-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Severe asthma is a heterogeneous syndrome, encompassing several distinct clinical phenotypes. Different molecular and cellular pathways or endotypes determine the type of underlying airway inflammation in patients with severe asthma, which can be categorized as eosinophilic asthma (allergic and nonall...

journal_title：Current opinion in pulmonary medicine

authors： Brusselle GG,Joos G

更新日期：2014-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) represent two of the most prevalent chronic respiratory disorders and cardiovascular diseases are major co-morbidities in both. Co-existence of both disorders (overlap syndrome) occurs in 1% of adults and overlap patients h...

journal_title：Current opinion in pulmonary medicine

authors： Lee R,McNicholas WT

更新日期：2011-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) affects over 12 million adults in the United States and is the third leading cause of 30-day readmissions. COPD is costly with almost $50 billion in direct costs annually. Total COPD costs can be up to double the identified direct costs because of comorbid ...

journal_title：Current opinion in pulmonary medicine

authors： Press VG,Konetzka RT,White SR

更新日期：2018-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the current use of oral corticosteroids (OCS) as a chronic treatment in patients with severe asthma and as a rescue treatment for patients presenting with acute exacerbations. RECENT FINDINGS:Airways disease is responsible for the bulk of OCS use in the community and considerable OCS-assoc...

journal_title：Current opinion in pulmonary medicine

authors： Pavord ID

更新日期：2019-01-01 00:00:00

abstract：:The goal of management of patients with respiratory failure is to restore them to a state of quiet breathing, without complication. This goal is often achieved by pharmacotherapy alone. Inhaled albuterol sulfate, oxygen, and systemic corticosteroids are mainstays of acute care drug management, whereas other data suppo...

journal_title：Current opinion in pulmonary medicine

authors： Gluckman TJ,Corbridge T

更新日期：2000-01-01 00:00:00

abstract：:Pulmonary embolism occurs in more than 175,000 patients each year in the United States. The objectives of treatment are to prevent death from the existing embolus, to prevent death and morbidity from recurrent pulmonary embolism, and to prevent morbidity from recurrent deep-vein thrombosis. For patients with adequate ...

journal_title：Current opinion in pulmonary medicine

authors： Raskob GE

更新日期：1999-07-01 00:00:00