Pulmonary hypertension due to interstitial lung disease.

abstract：PURPOSE OF REVIEW:Disorders of glucose metabolism, including insulin resistance, prediabetes, and diabetes, have been identified as risk factors for worsened asthma. This review summarizes emerging evidence for their role as modifiable risk factors in asthma, including the potential benefit of diabetes medications on a...

journal_title：Current opinion in pulmonary medicine

authors： Wu TD

更新日期：2021-01-01 00:00:00

abstract：:Intrathoracic neoplasms other than bronchogenic carcinoma comprise a disparate group of tumors that have in common an anatomic location within the thorax. For the purposes of this review, they are divided into three categories: pulmonary metastases from locations other than the thorax, mediastinal neoplasms, and unusu...

journal_title：Current opinion in pulmonary medicine

authors： Yoneda KY,Tharratt RS

更新日期：1997-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Severe asthma is a heterogeneous syndrome, encompassing several distinct clinical phenotypes. Different molecular and cellular pathways or endotypes determine the type of underlying airway inflammation in patients with severe asthma, which can be categorized as eosinophilic asthma (allergic and nonall...

journal_title：Current opinion in pulmonary medicine

authors： Brusselle GG,Joos G

更新日期：2014-01-01 00:00:00

abstract：:Thoracic empyema remains a significant medical problem in 1996. Patients in whom empyema develops suffer significant morbidity, frequently require prolonged hospitalizations, and are at an increased risk of death. In this review of parapneumonic effusions and empyema, four topics are discussed: diagnosis of empyema, t...

journal_title：Current opinion in pulmonary medicine

authors： Sasse SA

更新日期：1996-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This article aims to review the most recent proteomic findings in tissue and biological fluids and application of new technologies for the study of interstitial lung diseases. RECENT FINDINGS:New insights into lung cell biology as well as novel pathogenetic pathways of different interstitial lung dis...

journal_title：Current opinion in pulmonary medicine

authors： Rottoli P,Bargagli E,Landi C,Magi B

更新日期：2009-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Sarcoidosis is a granulomatous systemic disease of unknown cause where the lung is the most frequently affected organ. Therapeutic management of the disease is challenging as clinical presentation and prognosis are very heterogeneous. In the present review, we will summarize the main advances in sarco...

journal_title：Current opinion in pulmonary medicine

authors： Sellarés J,Francesqui J,Llabres M,Hernandez-Gonzalez F,Baughman RP

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Parasitic pneumonia is being increasingly reported from many parts of the world due to globalization and travel across the continents. This review outlines the recent developments in the diagnosis and management of parasitic pneumonias. RECENT FINDINGS:A polymerase chain reaction that can differentia...

journal_title：Current opinion in pulmonary medicine

authors： Vijayan VK

更新日期：2007-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Idiopathic pulmonary fibrosis (IPF) is a progressive, invariably fatal condition with a median survival from diagnosis of only 3 years. Despite improvements in disease understanding, challenges remain in establishing a diagnosis and predicting prognosis in individual patients. Furthermore, limited und...

journal_title：Current opinion in pulmonary medicine

authors： Maher TM

更新日期：2013-09-01 00:00:00

abstract：:Some time ago, the Th2 cytokine, interleukin (IL)-13, was identified as a critical regulator of the allergic response. Initial studies in animal models of disease provided compelling evidence that IL-13, independent from other Th2 cytokines, was necessary and sufficient to induce all features of allergic asthma. This ...

journal_title：Current opinion in pulmonary medicine

authors： Wills-Karp M,Chiaramonte M

更新日期：2003-01-01 00:00:00

abstract：PURPOSE OF REVIEW:After 'curative' resection, many patients are still at risk for further lung cancer, either as a recurrence or a new metachronous primary. In theory, close follow-up should improve survival by catching relapse early - but in reality, many experts feel that surveillance for recurrence is of uncertain v...

journal_title：Current opinion in pulmonary medicine

authors： Chang CF,Gould M

更新日期：2017-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Nuclear medicine techniques have the capacity to investigate neuronal dysfunction at the synapse level. For instance, metaiodobenzylguanidine (MIBG) shows a similar uptake, storage and release as norepinephrine. Intravenously injected radiolabeled MIBG is able to reflect neuronal damage induced by inf...

journal_title：Current opinion in pulmonary medicine

authors： van Kroonenburgh M,Mostard R,Vöö S

更新日期：2010-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Adherence to asthma therapies is poor leading to unnecessary morbidity and increased use of emergency and hospital resources. Strategies to improve adherence have not been successful. RECENT FINDINGS:Asthma adherence disease management is a clinical method to improve adherence for asthma patients. Th...

journal_title：Current opinion in pulmonary medicine

authors： Weinstein AG

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Diagnosis of idiopathic interstitial pneumonias (IIPs) requires the exclusion of, among others, concomitant connective tissue diseases (CTDs), which may present as interstitial lung disease (ILD). This review focuses on the evaluation required to separate these entities through serology, although not ...

journal_title：Current opinion in pulmonary medicine

authors： Papiris SA,Kagouridis K,Bouros D

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights recent developments in liver disease associated with cystic fibrosis. RECENT FINDINGS:The broad spectrum of hepatobiliary problems in cystic fibrosis includes specific alterations ascribable to the underlying defect as well as lesions of iatrogenic origin or that reflect the ef...

journal_title：Current opinion in pulmonary medicine

authors： Colombo C

更新日期：2007-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update on the implementation of precision medicine, based on treatable traits and mechanisms, in the daily clinical management of chronic airways diseases. RECENT FINDINGS:Recent insights into the complex and heterogeneous nature of chronic airway diseases including chronic obstructive ...

journal_title：Current opinion in pulmonary medicine

authors： Ulrik CS,Vijverberg S,Hanania NA,Diamant Z

更新日期：2020-01-01 00:00:00

abstract：:Parapneumonic effusions are frequent complications of bacterial pneumonia. Depending on the severity of the underlying pneumonia, the promptness of antibiotic therapy, and the virulence of the infecting organism, 5% to 50% of patients will require pleural fluid drainage to prevent progression to an empyema. The decisi...

journal_title：Current opinion in pulmonary medicine

authors： Heffner JE

更新日期：1996-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this article is to provide understanding of renal sarcoidosis, the different types of renal sarcoidosis, disease burden of renal involvement, and treatment options. RECENT FINDINGS:The frequency of renal involvement seems to be underestimated, but renal sarcoidosis represents a relevan...

journal_title：Current opinion in pulmonary medicine

authors： Bergner R,Löffler C

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Advances in imaging technologies and biomarker research offer hope that the incidence and mortality of lung cancer can be reduced by screening similar to what have been achieved for cancer of the cervix, breast, and colon. RECENT FINDINGS:Spiral computed tomography with multitrack scanners and autofl...

journal_title：Current opinion in pulmonary medicine

authors： McWilliams A,Lam S

更新日期：2005-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Since the introduction especially of multidetector computed tomography scanners, detection of peripheral pulmonary nodules as small as 2-3 mm is now a frequent event even in individuals without a significant smoking history. This preponderance of small indeterminate nodules has necessitated reconsider...

journal_title：Current opinion in pulmonary medicine

authors： Shiau MC,Bonavita J,Naidich DP

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:In cystic fibrosis (CF) patients with end-stage pulmonary disease, lung transplantation (LTx) remains a life-extending therapy with good outcome in most patients. Despite early concern about chronic pretransplantation infections in the context of posttransplantation immunosuppression, typical CF-assoc...

journal_title：Current opinion in pulmonary medicine

authors： Dupont L

更新日期：2017-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Subsequent to the ATS/ERS consensus classification of idiopathic interstitial pneumonia, non-specific interstitial pneumonia pattern was the dominant pattern in many collagen vascular diseases, which may explain the better prognosis of interstitial pneumonia associated with collagen disease than idiop...

journal_title：Current opinion in pulmonary medicine

authors： Kim DS

更新日期：2006-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Heparin-induced thrombocytopenia is a severe side effect of treatment with unfractionated heparin. The relation of low-molecular-weight heparin to heparin-induced thrombocytopenia is less well understood. This review will summarize what is known about the similarities and differences between thrombocy...

journal_title：Current opinion in pulmonary medicine

authors： Walenga JM,Prechel M,Jeske WP,Bakhos M

更新日期：2005-09-01 00:00:00

abstract：:Corticosteroids were the mainstay of therapy for idiopathic pulmonary fibrosis (IPF) for more than four decades, but their efficacy is unproven and toxicities are substantial. The course of IPF is characterized by progressive respiratory insufficiency, leading to death within 3 to 8 years from the onset of symptoms. A...

journal_title：Current opinion in pulmonary medicine

authors： Lynch JP 3rd,White E,Flaherty K

更新日期：2001-09-01 00:00:00

abstract：:Considerable progress has been made over the past 2 decades in defining and measuring health-related quality of life (QOL), and there is a growing recognition that these measures provide unique information about the impact of a chronic illness and its treatment. For patients with cystic fibrosis (CF), health-related Q...

journal_title：Current opinion in pulmonary medicine

authors： Quittner AL

更新日期：1998-11-01 00:00:00

abstract：:Apoptosis, also known as activation-induced cell death or programmed cell death, is an active suicide mechanism that is involved in normal tissue turnover during embryogenesis and adult life. There are many examples of apoptosis in the immune system, including programmed cell death of T cells during negative intrathym...

journal_title：Current opinion in pulmonary medicine

authors： Agostini C,Perin A,Semenzato G

更新日期：1998-09-01 00:00:00

abstract：:Bronchial carcinoids and hamartomas are, respectively, the most common malignant and benign unusual primary lung neoplasms. These tumors are often asymptomatic but can cause central airway obstruction. Helical computed tomographic and radionuclide scintigraphic advances in their detection and evolution, together with ...

journal_title：Current opinion in pulmonary medicine

authors： Chan AL,Shelton DK,Yoneda KY

更新日期：2001-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Classic descriptions of chronic obstructive pulmonary disease (COPD) centered on its impact on respiratory function. It is currently recognized that comorbidities contribute to the severity of symptoms and COPD progression. Understanding COPD-comorbidities associations could provide innovative treatme...

journal_title：Current opinion in pulmonary medicine

authors： Brown JP,Martinez CH

更新日期：2016-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This manuscript reviews the recent literature related to new developments in the understanding of existing and novel virulence factors of the pneumococcus that are of potential importance in the development of novel preventive and therapeutic strategies. RECENT FINDINGS:The pneumococcal capsule and p...

journal_title：Current opinion in pulmonary medicine

authors： Feldman C,Anderson R

更新日期：2020-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Telomere attrition has been proposed as one of the aging hallmarks in pulmonary fibrosis. Telomere shortening and telomerase gene mutations have been widely evaluated in recent years. Reduced telomere length may be identified in a quarter of patients with sporadic idiopathic pulmonary fibrosis (IPF) a...

journal_title：Current opinion in pulmonary medicine

authors： Molina-Molina M,Borie R

更新日期：2018-09-01 00:00:00

abstract：:The neurotrophins are a family of peptides that promote survival, growth, and differentiation of neurons. Neurotrophins may also influence the function of nonneuronal cell types, including immune cells. The development and maintenance of asthma is thought to involve the nervous system and the immune system, but the ro...

journal_title：Current opinion in pulmonary medicine

authors： Carr MJ,Hunter DD,Undem BJ

更新日期：2001-01-01 00:00:00