Renal sarcoidosis: approach to diagnosis and management.

Abstract:

PURPOSE OF REVIEW:The purpose of this article is to provide understanding of renal sarcoidosis, the different types of renal sarcoidosis, disease burden of renal involvement, and treatment options. RECENT FINDINGS:The frequency of renal involvement seems to be underestimated, but renal sarcoidosis represents a relevant group of organ manifestations and significantly adds to the patient's morbidity. Because histopathological analysis of renal biopsy specimens can reveal various entities, a diagnostic workup is necessary in every patient with sarcoidosis. SUMMARY:If systematically screened for renal manifestations are likely to occur in up to 25-30% of all sarcoidosis patients. The most common histological form of renal sarcoidosis is the granulomatous interstitial nephritis; however, granulomas can be absent. Furthermore, one can find various forms of secondary glomerulonephritis. In cases with dysregulated calcium homeostasis, nephrocalcinosis and nephrolithiasis are commonly detectable kidney diseases. AA amyloidosis or renal masses because of granuloma formation are considered to be rare manifestations. In addition to glucocorticoids various immunosuppressive treatments such as tumor necrosis factor alpha inhibitors have proven to be effective based on case series.

journal_name

Curr Opin Pulm Med

authors

Bergner R,Löffler C

doi

10.1097/MCP.0000000000000504

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

513-520

issue

5

eissn

1070-5287

issn

1531-6971

journal_volume

24

pub_type

杂志文章,评审
  • Drug-resistant tuberculosis: worldwide trends, problems specific to Eastern Europe and other hotspots, and the threat to developing countries.

    abstract::Although it had been appreciated that high levels of antituberculous drug resistance existed in some regions of the world, the full extent of the problem was not known. A combined initiative by the World Health Organization and the International Union Against Tuberculosis and Lung Disease was launched in 1994 to addre...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-200105000-00006

    authors: Willcox PA

    更新日期:2001-05-01 00:00:00

  • Unfractionated heparin compared with low-molecular-weight heparin as related to heparin-induced thrombocytopenia.

    abstract:PURPOSE OF REVIEW:Heparin-induced thrombocytopenia is a severe side effect of treatment with unfractionated heparin. The relation of low-molecular-weight heparin to heparin-induced thrombocytopenia is less well understood. This review will summarize what is known about the similarities and differences between thrombocy...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.mcp.0000174232.78219.03

    authors: Walenga JM,Prechel M,Jeske WP,Bakhos M

    更新日期:2005-09-01 00:00:00

  • What is the role of noninvasive ventilation in cystic fibrosis?

    abstract:PURPOSE OF REVIEW:The use of noninvasive ventilatory support in patients with cystic fibrosis (CF) has increased exponentially over the past 2 decades. This review examines the current knowledge and considers potential future directions for use of noninvasive ventilation in CF patients. RECENT FINDINGS:Noninvasive ven...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000105

    authors: Bright-Thomas RJ,Johnson SC

    更新日期:2014-11-01 00:00:00

  • Computed tomographic imaging of bronchiolar disorders.

    abstract::The bronchiolitides can be categorized broadly as constrictive or proliferative, each with characteristic CT features. The cardinal CT signs of constrictive bronchiolitis are mosaic perfusion, enhanced on expiratory CT scan and variably associated with bronchiectasis and, less frequently, centrilobular branching struc...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-199803000-00005

    authors: Wells AU

    更新日期:1998-03-01 00:00:00

  • Pulmonary hypertension and granulomatous vasculitis in sarcoidosis.

    abstract:PURPOSE OF REVIEW:To examine the recent advancements of the epidemiology, pathophysiology, clinical characteristics, radiographic studies, diagnostic modalities, treatment, and prognosis of pulmonary hypertension in sarcoidosis. RECENT FINDINGS:A large retrospective study found 73.8% of patients with sarcoidosis liste...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e328273bc5c

    authors: Shigemitsu H,Nagai S,Sharma OP

    更新日期:2007-09-01 00:00:00

  • Measurement of airway inflammation in asthma.

    abstract::Chronic airway inflammation is considered responsible for symptoms and disorders of airway function associated with asthma. This process is the target of anti-inflammatory therapy, so a number of standardized, noninvasive techniques have been developed to assess it. More recent approaches include the measurement of ex...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-200201000-00005

    authors: Wilson N

    更新日期:2002-01-01 00:00:00

  • Infectious lung complications in patients with HIV/AIDS.

    abstract:PURPOSE OF REVIEW:The aim of this article is to review recent observations in the area of infectious lung complications in individuals with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). Since the immunodeficiency was first characterized, it has been associated with enhanced susceptibilit...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.mcp.0000156992.53246.f8

    authors: Boyton RJ

    更新日期:2005-05-01 00:00:00

  • External validation and comparison of recently described prediction rules for suspected pulmonary embolism.

    abstract:PURPOSE OF REVIEW:The assessment of pretest probability, allowing the categorization of patients clinically suspected of having pulmonary embolism in low, intermediate, and high clinical probability, is an essential step in contemporary diagnostic strategies because it permits limiting the number of additional diagnost...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.mcp.0000130329.21799.7b

    authors: Righini M,Bounameaux H

    更新日期:2004-09-01 00:00:00

  • Cancer in interstitial pulmonary fibrosis and sarcoidosis.

    abstract::The occurrence of lung cancer in patients with diffuse interstitial pulmonary disease is well-known. The incidence, however, varies and ranges from 9.8 to 38%. The pathogenesis of lung cancer in pulmonary fibrosis is unclear, but genetic as well as environmental factors seem to be involved. ...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-200309000-00010

    authors: Sharma OP,Lamb C

    更新日期:2003-09-01 00:00:00

  • Adenocarcinoma of the lung: current concepts in radiologic diagnosis and management.

    abstract:PURPOSE OF REVIEW:Since the introduction especially of multidetector computed tomography scanners, detection of peripheral pulmonary nodules as small as 2-3 mm is now a frequent event even in individuals without a significant smoking history. This preponderance of small indeterminate nodules has necessitated reconsider...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e3281c9b107

    authors: Shiau MC,Bonavita J,Naidich DP

    更新日期:2007-07-01 00:00:00

  • Cardiovascular consequences of obstructive sleep apnea in different study models and novel perspectives.

    abstract:PURPOSE OF REVIEW:Obstructive sleep apnea (OSA) is heterogeneous in terms of contributing pathophysiological mechanisms, clinical presentation, and consequences. Different study models from animal models of intermittent hypoxia over case-control, cohort, and population-based observational studies to uncontrolled interv...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章

    doi:10.1097/MCP.0000000000000618

    authors: Schwarz EI

    更新日期:2019-11-01 00:00:00

  • Pleural effusions in acute idiopathic pericarditis and postcardiac injury syndrome.

    abstract:PURPOSE OF REVIEW:Pleural effusions are frequent in the context of acute idiopathic pericarditis and following pericardiotomy, but they have seldom been characterized. This review summarizes their most relevant clinical features. RECENT FINDINGS:In acute idiopathic pericarditis, pleural effusions tend to be left-sided...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000383

    authors: Porcel JM

    更新日期:2017-07-01 00:00:00

  • Acute and chronic frontal sinusitis.

    abstract::This review summarizes the recent literature published on the microbiology, diagnosis, and medical and surgical management of acute and chronic frontal sinus disease. Two retrospective studies investigated the microbiology of frontal sinusitis in patients that underwent sinus surgery. Streptococcus pneumoniae, Haemoph...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-200305000-00003

    authors: Brook I

    更新日期:2003-05-01 00:00:00

  • Update in airway stents.

    abstract:PURPOSE OF REVIEW:Malignant central airway obstruction heavily impacts patients' quality of life and its management continues to be a challenge. The current article will review the use of airway stents in this population. RECENT FINDINGS:Airway stenting is highly effective in palliating symptoms of airway obstruction....

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e32833a260

    authors: Casal RF

    更新日期:2010-07-01 00:00:00

  • Bronchiolitis with airflow obstruction.

    abstract::Bronchiolar lesions are becoming increasingly recognized as an important cause of airflow obstruction. For this reason, it is helpful to have an update of the current clinical, radiographic, and immunologic perspective. Among the bronchiolar airflow disorders, diffuse panbronchiolitis is related to HLA antigen Bw54, a...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Epler GR

    更新日期:1995-03-01 00:00:00

  • Playing the odds: lung cancer surveillance after curative surgery.

    abstract:PURPOSE OF REVIEW:After 'curative' resection, many patients are still at risk for further lung cancer, either as a recurrence or a new metachronous primary. In theory, close follow-up should improve survival by catching relapse early - but in reality, many experts feel that surveillance for recurrence is of uncertain v...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000381

    authors: Chang CF,Gould M

    更新日期:2017-07-01 00:00:00

  • Uncommon respiratory pathogens.

    abstract:PURPOSE OF REVIEW:In many cases, the specific pathogen responsible for a respiratory infection is not identified and can lead to improper medical treatment, increased duration of illness, and possibly contributes to the development of antibiotic resistance. Molecular-based diagnostic methodologies have significantly im...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.mcp.0000219274.65557.dc

    authors: Lednicky JA,Rayner JO

    更新日期:2006-05-01 00:00:00

  • Parasitic lung infections.

    abstract:PURPOSE OF REVIEW:Global climate change and population explosion leading to changes in natural ecosystem and travel across the continents have resulted in an increase in the transmission of parasites to human beings. This review focuses on recent advancements in parasitic lung infections. RECENT FINDINGS:Invasive para...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e328326f3f8

    authors: Vijayan VK

    更新日期:2009-05-01 00:00:00

  • Update on the diagnosis and classification of ILD.

    abstract:PURPOSE OF REVIEW:The purpose of this review is to provide an update on the diagnosis and classification of interstitial lung disease (ILD), with a specific focus on newly described ILD subtypes and phenotypes. In addition, the strengths and limitations of the current approach to ILD diagnosis and management are discus...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e328363f48d

    authors: Ryerson CJ,Collard HR

    更新日期:2013-09-01 00:00:00

  • Prognosis in cystic fibrosis.

    abstract::Prognosis for patients with cystic fibrosis has improved dramatically over the past three decades. In the United States, median survival age is now 28.9 years. Although genotype predicts exocrine pancreatic function, it does not correlate with pulmonary status or overall clinical outcome. However, there are a number o...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-199511000-00003

    authors: Rosenstein BJ,Zeitlin PL

    更新日期:1995-11-01 00:00:00

  • The use of adenosine deaminase and adenosine deaminase isoenzymes in the diagnosis of tuberculous pleuritis.

    abstract::The bacillary population described in tuberculous pleuritis is small, and its most likely pathogenetic mechanism is essentially immunologic. This explains why, until now, the diagnostic identification of tuberculous pleuritis (TP) has been based on the presence of granulomas in pleural biopsy. Correcting this diagnost...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-200007000-00002

    authors: Pérez-Rodriguez E,Jiménez Castro D

    更新日期:2000-07-01 00:00:00

  • Sleep deprivation: a mind-body approach.

    abstract:PURPOSE OF REVIEW:The purpose of this review is to summarize recent advances in our understanding of the impact sleep disturbances have on our health, with particular focus on the brain. The present review considers the influence of sleep disturbance on the neurovascular unit; the role of sleep disturbance in neurodege...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000323

    authors: Aguirre CC

    更新日期:2016-11-01 00:00:00

  • Improving adherence to asthma therapies.

    abstract:PURPOSE OF REVIEW:Adherence to asthma therapies is poor leading to unnecessary morbidity and increased use of emergency and hospital resources. Strategies to improve adherence have not been successful. RECENT FINDINGS:Asthma adherence disease management is a clinical method to improve adherence for asthma patients. Th...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000128

    authors: Weinstein AG

    更新日期:2015-01-01 00:00:00

  • Screening for lung cancer: a review.

    abstract:PURPOSE OF REVIEW:After the disappointing results of lung cancer screening trials conducted in the 1960s to the 1980s, a renewed interest in lung cancer screening emerged in the 1990s with the development of new technologies such as low-dose spiral CT. The literature regarding screening with biomarkers and CT continues...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.mcp.0000128432.79891.85

    authors: Manser R

    更新日期:2004-07-01 00:00:00

  • Pulmonary disease in rescue workers at the World Trade Center site.

    abstract:PURPOSE OF REVIEW:The catastrophic collapse of the World Trade Center (WTC) towers on September 11, 2001 created a large-scale disaster site in a densely populated urban environment. Over the ensuing months, tens of thousands of rescue, recovery and cleanup workers, volunteers, and residents of the adjacent community w...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.mcp.0000151716.96241.0a

    authors: Banauch GI,Dhala A,Prezant DJ

    更新日期:2005-03-01 00:00:00

  • Management of chronic obstructive pulmonary disease.

    abstract::Chronic obstructive pulmonary disease is the fourth leading cause of death in the United States, affecting approximately 10% of all adults. Several articles published during the past year contributed significantly to our understanding of the complicated management of this disease. New information concerning bronchodil...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-199603000-00011

    authors: Navin DM,Gross NJ

    更新日期:1996-03-01 00:00:00

  • Microbes and asthma: the missing cellular and molecular links.

    abstract:PURPOSE OF REVIEW:In this review, we describe the 'state-of-the-art' in our knowledge of asthma and what gaps exist, which can be exploited in the future for effective translation of our knowledge from the bench or population studies to diagnosis and therapy. RECENT FINDINGS:The advent of microbiome research has expan...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e32834dccc0

    authors: Brar T,Nagaraj S,Mohapatra S

    更新日期:2012-01-01 00:00:00

  • Chronic inflammation, chronic obstructive pulmonary disease, and lung cancer.

    abstract:PURPOSE OF REVIEW:Smoking is a major risk factor for lung cancer, which is the leading cause of cancer-related deaths both in the USA and worldwide. Chronic obstructive pulmonary disease and emphysema are comorbid conditions often found in lung cancer patients. The inflammatory pathways that link chronic obstructive pu...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e32832c975a

    authors: Lee G,Walser TC,Dubinett SM

    更新日期:2009-07-01 00:00:00

  • Asthma and food allergy.

    abstract:PURPOSE OF REVIEW:Food allergy associated clinical and social burdens have increased substantially in prevalence in the past decade. Coexisting asthma is a significant problem as food reactions tend to be more severe when they involve the lung. Food allergy also increases asthma morbidity in adults and children. RECEN...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e3282f1981c

    authors: Ozol D,Mete E

    更新日期:2008-01-01 00:00:00

  • Dornase alfa (Pulmozyme).

    abstract:PURPOSE OF REVIEW:Dornase alfa (Pulmozyme) is one of the most commonly used medications to treat the lung disease of cystic fibrosis (CF). As other respiratory medications have entered the clinical market, understanding the proper use and indication for dornase alfa is increasingly important. In addition, dornase alfa ...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e328358d51f

    authors: Wagener JS,Kupfer O

    更新日期:2012-11-01 00:00:00