Dornase alfa (Pulmozyme).

abstract：:Although it had been appreciated that high levels of antituberculous drug resistance existed in some regions of the world, the full extent of the problem was not known. A combined initiative by the World Health Organization and the International Union Against Tuberculosis and Lung Disease was launched in 1994 to addre...

journal_title：Current opinion in pulmonary medicine

authors： Willcox PA

更新日期：2001-05-01 00:00:00

abstract：:An important advance in our understanding of the pathophysiology of asthma has been the discovery that airway inflammation is not confined to severe asthma but also characterizes mild and moderate asthma. Inflammation in asthma may be the result of a peculiar type of lymphocytic inflammation whereby Th2 lymphocytes se...

journal_title：Current opinion in pulmonary medicine

authors： Fahy JV,Corry DB,Boushey HA

更新日期：2000-01-01 00:00:00

abstract：:Bronchial carcinoids and hamartomas are, respectively, the most common malignant and benign unusual primary lung neoplasms. These tumors are often asymptomatic but can cause central airway obstruction. Helical computed tomographic and radionuclide scintigraphic advances in their detection and evolution, together with ...

journal_title：Current opinion in pulmonary medicine

authors： Chan AL,Shelton DK,Yoneda KY

更新日期：2001-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Obstructive sleep apnea (OSA) is heterogeneous in terms of contributing pathophysiological mechanisms, clinical presentation, and consequences. Different study models from animal models of intermittent hypoxia over case-control, cohort, and population-based observational studies to uncontrolled interv...

journal_title：Current opinion in pulmonary medicine

authors： Schwarz EI

更新日期：2019-11-01 00:00:00

abstract：:Thoracic empyema remains a significant medical problem in 1996. Patients in whom empyema develops suffer significant morbidity, frequently require prolonged hospitalizations, and are at an increased risk of death. In this review of parapneumonic effusions and empyema, four topics are discussed: diagnosis of empyema, t...

journal_title：Current opinion in pulmonary medicine

authors： Sasse SA

更新日期：1996-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Although known for several decades, catamenial pneumothorax has been considered until recently as an extremely rare entity. The condition is now more easily recognized and several studies have been published, with somewhat relevant discrepancies with respect to etiologic, epidemiologic, and management...

journal_title：Current opinion in pulmonary medicine

authors： Alifano M

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Symptoms of anxiety and depression are prevalent in at least 20-40% of patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) and are known to affect prognosis and worsen quality of life. This review examines whether pulmonary rehabilitation can effectively improve psychological...

journal_title：Current opinion in pulmonary medicine

authors： Coventry PA

更新日期：2009-03-01 00:00:00

abstract：:Acute bronchitis in previously fit individuals is a common condition that is usually mild and self limiting. Chronic bronchitis remains a common cause of morbidity and mortality, and the cost to the nation due to lost working days and to health services is enormous. Cigarette smoking is the major etiologic factor, alt...

journal_title：Current opinion in pulmonary medicine

authors： Wilson R,Rayner CF

更新日期：1995-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Idiopathic pulmonary fibrosis (IPF) is a progressive, invariably fatal condition with a median survival from diagnosis of only 3 years. Despite improvements in disease understanding, challenges remain in establishing a diagnosis and predicting prognosis in individual patients. Furthermore, limited und...

journal_title：Current opinion in pulmonary medicine

authors： Maher TM

更新日期：2013-09-01 00:00:00

abstract：:As the number of inhaled drugs available for cystic fibrosis grows, there is increasing awareness of delivery device issues. Current jet and ultrasonic nebulizers are inefficient at delivering drugs to the lower respiratory tract. There are large differences in output characteristics between nebulizers and high inters...

journal_title：Current opinion in pulmonary medicine

authors： Geller DE

更新日期：1997-11-01 00:00:00

abstract：:Wheezing in infants and children presents a difficult differential diagnosis contingent on the presenting symptoms and age of the child. A determination of the anatomy of the lower airway, combined with allergic, infectious, and noninfectious irritants, is requisite to a complete evaluation. The intervention strategie...

journal_title：Current opinion in pulmonary medicine

authors： Chipps BE,Chipps DR

更新日期：1999-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This article explains the high comorbidity of craniofacial pain (chronic face pain, temporomandibular disorders, and primary headaches) with obstructive sleep breathing disorders and obstructive sleep apnea (OSA). It is recommended that physicians treating OSA should be aware of the concurrent chronic...

journal_title：Current opinion in pulmonary medicine

authors： Olmos SR

更新日期：2016-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines the current reports, the evidence and the issues surrounding the use of non-invasive ventilation (NIV) for the treatment of chronic obstructive pulmonary disease (COPD) in both the acute and domiciliary setting. RECENT FINDINGS:With the increasing use of NIV, more recent studies ...

journal_title：Current opinion in pulmonary medicine

authors： Ramsay M,Hart N

更新日期：2013-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients with lung cancer are particularly vulnerable to lung injury associated with immune checkpoint inhibition and often present with more frequent and more severe manifestations of lung disease compared to patients with other tumor types. The present review explores the reasons for increased susce...

journal_title：Current opinion in pulmonary medicine

authors： Shannon VR

更新日期：2020-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The objective is to discuss recent progress in our understanding of the role of the indoor environment in asthma, focusing on the special role of cat allergens. RECENT FINDINGS:Sensitization to Fel d 1 is the dominant event in inhalant responses to cat; however, there are also IgE responses to the li...

journal_title：Current opinion in pulmonary medicine

authors： Kelly LA,Erwin EA,Platts-Mills TA

更新日期：2012-01-01 00:00:00

abstract：:Apoptosis, also known as activation-induced cell death or programmed cell death, is an active suicide mechanism that is involved in normal tissue turnover during embryogenesis and adult life. There are many examples of apoptosis in the immune system, including programmed cell death of T cells during negative intrathym...

journal_title：Current opinion in pulmonary medicine

authors： Agostini C,Perin A,Semenzato G

更新日期：1998-09-01 00:00:00

abstract：:While the most recent trend in secondary prophylaxis after venous thromboembolism has been toward a prolonged duration, it has become obvious that individualization according to risk factors is crucial. Subgroup analyses in a long-term follow-up of a previous trial, as well as new trials on patients with idiopathic th...

journal_title：Current opinion in pulmonary medicine

authors： Schulman S

更新日期：2000-07-01 00:00:00

abstract：:Pulmonary disease remains a major problem for the 33 million individuals who are thought to be infected with human immunodeficiency virus (HIV) worldwide. Respiratory infections are responsible for a large number of the 2 million deaths that occur each year in association with HIV disease. In countries where the major...

journal_title：Current opinion in pulmonary medicine

authors： Ashley EA,Johnson MA,Lipman MC

更新日期：2000-05-01 00:00:00

abstract：:Chest tubes and their accompanying pleural drainage units continue to present challenging questions regarding their optimal use. Appropriate chest tube size selection to accommodate the clinical situation is key, especially in the setting of large pleural air leaks lest a tension pneumothorax ensue. Connection of an a...

journal_title：Current opinion in pulmonary medicine

authors： Baumann MH

更新日期：2003-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The catastrophic collapse of the World Trade Center (WTC) towers on September 11, 2001 created a large-scale disaster site in a densely populated urban environment. Over the ensuing months, tens of thousands of rescue, recovery and cleanup workers, volunteers, and residents of the adjacent community w...

journal_title：Current opinion in pulmonary medicine

authors： Banauch GI,Dhala A,Prezant DJ

更新日期：2005-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The Sleep Heart Health Study began in 1994 as a prospective cohort study of cardiovascular disease. The results of longitudinal analysis are not yet available, but numerous analyses of cross-sectional data have been published. This review provides an overview of study results so far. RECENT FINDINGS:...

journal_title：Current opinion in pulmonary medicine

authors： Gottlieb DJ

更新日期：2008-11-01 00:00:00

abstract：PURPOSE OF REVIEW:It has been an ongoing challenge to translate knowledge pertaining to the molecular basis of cystic fibrosis (CF) into a clear understanding of the development of CF lung disease. Various hypotheses have attempted to explain the apparent breach of innate defenses in CF, although a definitive explanati...

journal_title：Current opinion in pulmonary medicine

authors： Donaldson SH,Boucher RC

更新日期：2003-11-01 00:00:00

abstract：:Thoracoscopy has received increasing attention over the past decade as a result of the considerable advances that have been made in the development of endoscopic instruments. In contrast to the newly established video-assisted thoracoscopic surgery, the classic way to perform thoracoscopy is using only local anesthesi...

journal_title：Current opinion in pulmonary medicine

authors： Loddenkemper R,Schönfeld N

更新日期：1998-07-01 00:00:00

abstract：PURPOSE OF REVIEW:There has been much recent interest in the use of macrolide antibiotics as chronic suppressive therapy in patients with cystic fibrosis. Three recent randomized, placebo-controlled trials have been conducted. RECENT FINDINGS:All three trials used similar regimens of azithromycin, and lung function im...

journal_title：Current opinion in pulmonary medicine

authors： Saiman L

更新日期：2004-11-01 00:00:00

abstract：:Disorders of sleep in children are distinctly different from sleep disorders in adults. Since children are forced to constantly learn and adapt, the effects of disordered sleep may be more profound. This paper reviews the disorders of sleep that are most significant in each of the stages of development from infancy to...

journal_title：Current opinion in pulmonary medicine

authors： Anstead M

更新日期：2000-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Lung cancer is the leading cause of cancer mortality in men and women. Most patients present with advanced disease and face significant morbidity, with many reporting distressing symptoms throughout the course of their illness. The purpose of this review is to highlight the recent studies that support...

journal_title：Current opinion in pulmonary medicine

authors： Shin J,Temel J

更新日期：2013-07-01 00:00:00

abstract：:The majority of men with cystic fibrosis (CF) have associated congenital bilateral absence of the vas deferens (CBVAD). This congenital defect results in the absence of the anatomic ducts through which spermatozoa pass from the testes to the urethra. No spermatozoa are found in the semen, a condition referred to as ob...

journal_title：Current opinion in pulmonary medicine

authors： Sokol RZ

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:After 'curative' resection, many patients are still at risk for further lung cancer, either as a recurrence or a new metachronous primary. In theory, close follow-up should improve survival by catching relapse early - but in reality, many experts feel that surveillance for recurrence is of uncertain v...

journal_title：Current opinion in pulmonary medicine

authors： Chang CF,Gould M

更新日期：2017-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim is to summarize the evidence base for tuberculosis (TB) diagnostics, review recent policies on TB diagnostics, and discuss issues such as how evidence is translated into policy, limitations of the existing evidence base, and challenges involved in translating policies into impact. RECENT FIND...

journal_title：Current opinion in pulmonary medicine

authors： Pai M,Minion J,Steingart K,Ramsay A

更新日期：2010-05-01 00:00:00

abstract：:Considerable progress has been made over the past 2 decades in defining and measuring health-related quality of life (QOL), and there is a growing recognition that these measures provide unique information about the impact of a chronic illness and its treatment. For patients with cystic fibrosis (CF), health-related Q...

journal_title：Current opinion in pulmonary medicine

authors： Quittner AL

更新日期：1998-11-01 00:00:00