The Sleep Heart Health Study: a progress report.

Abstract:

PURPOSE OF REVIEW:The Sleep Heart Health Study began in 1994 as a prospective cohort study of cardiovascular disease. The results of longitudinal analysis are not yet available, but numerous analyses of cross-sectional data have been published. This review provides an overview of study results so far. RECENT FINDINGS:Recent findings covered in this review include a methodological study supporting the choice of a 4% oxyhemoglobin desaturation criterion for identification of hypopneas; evidence that sleepiness may modify the association of sleep apnea with hypertension; the association of sleep apnea with increased left ventricular mass in a pattern suggesting predominantly eccentric left ventricular hypertrophy; the association of restless legs syndrome with an increase in prevalent cardiovascular disease; and the results of a genome-wide association study of sleep and circadian phenotypes. SUMMARY:Although designed as a prospective cohort study, analysis of cross-sectional data from the Sleep Heart Health Study has contributed numerous insights to the field of sleep medicine.

journal_name

Curr Opin Pulm Med

authors

Gottlieb DJ

doi

10.1097/MCP.0b013e328312ed61

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

537-42

issue

6

eissn

1070-5287

issn

1531-6971

pii

00063198-200811000-00007

journal_volume

14

pub_type

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