Biomarkers in asthma.

abstract：:Many individuals are now surviving their injuries to face the consequences of an activated immunoinflammatory system and the complications of supportive therapy. The pulmonary system bears the force of this insult. An understanding of the epidemiology of acute respiratory failure, as well as a greater knowledge of the...

journal_title：Current opinion in pulmonary medicine

authors： O'Keefe GE,Maier RV

更新日期：1997-05-01 00:00:00

abstract：:The majority of men with cystic fibrosis (CF) have associated congenital bilateral absence of the vas deferens (CBVAD). This congenital defect results in the absence of the anatomic ducts through which spermatozoa pass from the testes to the urethra. No spermatozoa are found in the semen, a condition referred to as ob...

journal_title：Current opinion in pulmonary medicine

authors： Sokol RZ

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights recent developments in liver disease associated with cystic fibrosis. RECENT FINDINGS:The broad spectrum of hepatobiliary problems in cystic fibrosis includes specific alterations ascribable to the underlying defect as well as lesions of iatrogenic origin or that reflect the ef...

journal_title：Current opinion in pulmonary medicine

authors： Colombo C

更新日期：2007-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This article aims to review the most recent proteomic findings in tissue and biological fluids and application of new technologies for the study of interstitial lung diseases. RECENT FINDINGS:New insights into lung cell biology as well as novel pathogenetic pathways of different interstitial lung dis...

journal_title：Current opinion in pulmonary medicine

authors： Rottoli P,Bargagli E,Landi C,Magi B

更新日期：2009-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) represent two of the most prevalent chronic respiratory disorders and cardiovascular diseases are major co-morbidities in both. Co-existence of both disorders (overlap syndrome) occurs in 1% of adults and overlap patients h...

journal_title：Current opinion in pulmonary medicine

authors： Lee R,McNicholas WT

更新日期：2011-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This article aims to review the geological background of environmental asbestos exposure and the distribution of asbestos-related disease (ARD) in association with naturally occurring asbestos (NOA), and discusses the potential health risks associated with exposure to non-occupational asbestos. RECEN...

journal_title：Current opinion in pulmonary medicine

authors： Bayram M,Bakan ND

更新日期：2014-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Time to clinical worsening (TTCW) can be used to assess disease progression associated with pulmonary arterial hypertension (PAH). As a consequence, it is highly relevant to patients, clinicians, and regulatory agencies. The majority of clinical trials of PAH-specific drug therapies have included TTCW...

journal_title：Current opinion in pulmonary medicine

authors： Galiè N,Simonneau G,Barst RJ,Badesch D,Rubin L

更新日期：2010-05-01 00:00:00

abstract：:The pleural space in healthy humans was thought to contain a few milliliters of fluid, based on extrapolation from animal studies. However, because of the obvious technical difficulties in atraumatically retrieving such a small volume of fluid, the exact volume and cellular content of human pleural fluid has not been ...

journal_title：Current opinion in pulmonary medicine

authors： Noppen M

更新日期：2001-07-01 00:00:00

abstract：:One aim of caring for adults and children with asthma should be the identification and treatment of the functional impairments that are troublesome to these patients in their daily lives. Studies have shown that correlations between measures of clinical asthma severity and control and health-related quality of life (H...

journal_title：Current opinion in pulmonary medicine

authors： Juniper EF

更新日期：1999-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Accurate diagnosis of interstitial lung diseases (ILDs) can be challenging, and a substantial percentage of ILD patients remain unclassifiable even after thorough assessment by an experienced multidisciplinary team. In this review, we summarize the recent literature on the definition, prevalence, diag...

journal_title：Current opinion in pulmonary medicine

authors： Guler SA,Ryerson CJ

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:It is increasingly clear that asthma is not a single disease, but a disorder with vast heterogeneity in pathogenesis, severity, and treatment response. In this review, we discuss the present understanding of different asthma phenotypes and endotypes, and the prospects of personalized medicine for asth...

journal_title：Current opinion in pulmonary medicine

authors： Lin TY,Poon AH,Hamid Q

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma is a chronic inflammatory disease in which changes in macrophage polarization have been shown to contribute to the pathogenesis. The present review discusses the contribution of changes in macrophage function to asthma related to polarization changes and elaborates on possible therapeutic strat...

journal_title：Current opinion in pulmonary medicine

authors： van der Veen TA,de Groot LES,Melgert BN

更新日期：2020-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The role of thoracic surgery in pulmonary tuberculosis, in either a diagnostic or a therapeutic role, is well established. This review aims to underline the current indications for lung resection, surgical strategy and outcomes associated with surgery. RECENT FINDINGS:There has been a renewed interes...

journal_title：Current opinion in pulmonary medicine

authors： Naidoo R

更新日期：2008-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Ever since sarcoidosis was first described, its relationship with tuberculosis has been debated. Whereas some consider sarcoidosis and tuberculosis as two extremes of the same disease process, other researchers have negated the role of mycobacteria in causation of sarcoidosis. Whether or not linked ca...

journal_title：Current opinion in pulmonary medicine

authors： Gupta D,Agarwal R,Aggarwal AN,Jindal SK

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Since the introduction especially of multidetector computed tomography scanners, detection of peripheral pulmonary nodules as small as 2-3 mm is now a frequent event even in individuals without a significant smoking history. This preponderance of small indeterminate nodules has necessitated reconsider...

journal_title：Current opinion in pulmonary medicine

authors： Shiau MC,Bonavita J,Naidich DP

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the current use of oral corticosteroids (OCS) as a chronic treatment in patients with severe asthma and as a rescue treatment for patients presenting with acute exacerbations. RECENT FINDINGS:Airways disease is responsible for the bulk of OCS use in the community and considerable OCS-assoc...

journal_title：Current opinion in pulmonary medicine

authors： Pavord ID

更新日期：2019-01-01 00:00:00

abstract：PURPOSE OF REVIEW:After the disappointing results of lung cancer screening trials conducted in the 1960s to the 1980s, a renewed interest in lung cancer screening emerged in the 1990s with the development of new technologies such as low-dose spiral CT. The literature regarding screening with biomarkers and CT continues...

journal_title：Current opinion in pulmonary medicine

authors： Manser R

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Symptoms of anxiety and depression are prevalent in at least 20-40% of patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) and are known to affect prognosis and worsen quality of life. This review examines whether pulmonary rehabilitation can effectively improve psychological...

journal_title：Current opinion in pulmonary medicine

authors： Coventry PA

更新日期：2009-03-01 00:00:00

abstract：:Diabetes is a common complication of cystic fibrosis. Because it is associated with increased morbidity and mortality, prompt diagnosis and aggressive management of cystic fibrosis-related diabetes is important. The Cystic Fibrosis Foundation held a consensus conference in 1998 to define the standards of care for pati...

journal_title：Current opinion in pulmonary medicine

authors： Riggs AC,Seaquist ER,Moran A

更新日期：1999-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To review and compare the constellations of causes and consequences of the two current pandemics, Covid-19 and climate change. RECENT FINDINGS:There has been a transient counterbalancing, in which the response to Covid-19 has briefly mitigated pollution and greenhouse gasses. This divergence belies m...

journal_title：Current opinion in pulmonary medicine

authors： Joshi M,Caceres J,Ko S,Epps SM,Bartter T

更新日期：2021-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Advances in imaging technologies and biomarker research offer hope that the incidence and mortality of lung cancer can be reduced by screening similar to what have been achieved for cancer of the cervix, breast, and colon. RECENT FINDINGS:Spiral computed tomography with multitrack scanners and autofl...

journal_title：Current opinion in pulmonary medicine

authors： McWilliams A,Lam S

更新日期：2005-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Ventilator-associated pneumonia (VAP) remains a frequent and severe complication in endotracheally intubated patients. Strict adherence to preventive measures reduces the risk of VAP. The objective of this paper is to review what has come forward in recent years in the nonpharmacological prevention of...

journal_title：Current opinion in pulmonary medicine

authors： Blot S,Rello J,Vogelaers D

更新日期：2011-05-01 00:00:00

abstract：:The most common syndromes associated with obstructive lung disease are asthma and chronic obstructive pulmonary disease (COPD). Evidence for a viral etiology of asthmatic exacerbations is well known, but evidence for a role for viruses in COPD exacerbation is just emerging. Viruses may cause chronic infection in both ...

journal_title：Current opinion in pulmonary medicine

authors： Seemungal TA,Wedzicha JA

更新日期：2003-03-01 00:00:00

abstract：:Staging of sarcoidosis needs a synthesis of clinical features, histology, radiology, biochemical changes, and immunologic aberrations to distinguish this disease from nonspecific sarcoid-tissue reactions. The main aim of this report is to offer readers an overview on immunologic markers that have been evaluated in the...

journal_title：Current opinion in pulmonary medicine

authors： Semenzato G,Bortoli M,Agostini C

更新日期：2002-09-01 00:00:00

abstract：:Prognosis for patients with cystic fibrosis has improved dramatically over the past three decades. In the United States, median survival age is now 28.9 years. Although genotype predicts exocrine pancreatic function, it does not correlate with pulmonary status or overall clinical outcome. However, there are a number o...

journal_title：Current opinion in pulmonary medicine

authors： Rosenstein BJ,Zeitlin PL

更新日期：1995-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update on the implementation of precision medicine, based on treatable traits and mechanisms, in the daily clinical management of chronic airways diseases. RECENT FINDINGS:Recent insights into the complex and heterogeneous nature of chronic airway diseases including chronic obstructive ...

journal_title：Current opinion in pulmonary medicine

authors： Ulrik CS,Vijverberg S,Hanania NA,Diamant Z

更新日期：2020-01-01 00:00:00

abstract：:The goal of management of patients with respiratory failure is to restore them to a state of quiet breathing, without complication. This goal is often achieved by pharmacotherapy alone. Inhaled albuterol sulfate, oxygen, and systemic corticosteroids are mainstays of acute care drug management, whereas other data suppo...

journal_title：Current opinion in pulmonary medicine

authors： Gluckman TJ,Corbridge T

更新日期：2000-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Adherence to asthma therapies is poor leading to unnecessary morbidity and increased use of emergency and hospital resources. Strategies to improve adherence have not been successful. RECENT FINDINGS:Asthma adherence disease management is a clinical method to improve adherence for asthma patients. Th...

journal_title：Current opinion in pulmonary medicine

authors： Weinstein AG

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Isolated distal deep-vein thrombosis (iDDVT) is a distal deep-vein thrombosis (DVT) without proximal DVT or pulmonary embolism. Although its clinical significance is uncertain, its prevalence is increasing with the use of whole leg compression ultrasonography. Epidemiological data giving reported rate...

journal_title：Current opinion in pulmonary medicine

authors： Galanaud JP,Bosson JL,Quéré I

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) imposes a large burden on the global population and even more so for the elderly who face significant obstacles in the diagnosis, management, and psychosocial effects of the disease. This review describes the current challenges and key points in the managem...

journal_title：Current opinion in pulmonary medicine

authors： Allen B,Aboussouan LS

更新日期：2021-03-01 00:00:00