Precision medicine and treatable traits in chronic airway diseases - where do we stand?

abstract：PURPOSE OF REVIEW:Adherence to asthma therapies is poor leading to unnecessary morbidity and increased use of emergency and hospital resources. Strategies to improve adherence have not been successful. RECENT FINDINGS:Asthma adherence disease management is a clinical method to improve adherence for asthma patients. Th...

journal_title：Current opinion in pulmonary medicine

authors： Weinstein AG

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To review and compare the constellations of causes and consequences of the two current pandemics, Covid-19 and climate change. RECENT FINDINGS:There has been a transient counterbalancing, in which the response to Covid-19 has briefly mitigated pollution and greenhouse gasses. This divergence belies m...

journal_title：Current opinion in pulmonary medicine

authors： Joshi M,Caceres J,Ko S,Epps SM,Bartter T

更新日期：2021-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) is one of the most prevalent and increasing health problems in the elderly on a worldwide scale. The management of COPD in older patients presents practical diagnostic and treatment issues, which are reviewed with reference to the stable stage of the diseas...

journal_title：Current opinion in pulmonary medicine

authors： Pistelli R,Ferrara L,Misuraca C,Bustacchini S

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypersensitivity pneumonitis (HP), also known as extrinsic allergic alveolitis, is a granulomatous, inflammatory disease of the lungs caused by the inhalation of antigenic organic particles or fumes. The disease may present as an acute, subacute, or chronic illness. Episodes of acute and subacute HP u...

journal_title：Current opinion in pulmonary medicine

authors： Mohr LC

更新日期：2004-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article is to examine the evidence for the effectiveness of systemic corticosteroids in managing acute asthma in children as it relates to the timing of its administration. RECENT FINDINGS:Three themes relevant to the timing of systemic corticosteroid administration as it relates to m...

journal_title：Current opinion in pulmonary medicine

authors： Bhogal SK

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to highlight seminal and current literature that informs our understanding of the clinical and investigative utility of biomarkers in asthma. Biomarkers derive from a variety of sources [bronchiolar lavage (BAL), sputum, exhaled breath, and blood], and have widely variant...

journal_title：Current opinion in pulmonary medicine

authors： Murugan A,Prys-Picard C,Calhoun WJ

更新日期：2009-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Common variable immunodeficiency (CVID) is the most common primary immunodeficiency characterized by a deficiency of immunoglobulins. Approximately 30% of the patients develop autoimmune and granulomatous disease. Similar to sarcoidosis, granulomatous disease in CVID can potentially affect all organs,...

journal_title：Current opinion in pulmonary medicine

authors： Prasse A,Kayser G,Warnatz K

更新日期：2013-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Idiopathic pulmonary fibrosis (IPF) is a progressive, invariably fatal condition with a median survival from diagnosis of only 3 years. Despite improvements in disease understanding, challenges remain in establishing a diagnosis and predicting prognosis in individual patients. Furthermore, limited und...

journal_title：Current opinion in pulmonary medicine

authors： Maher TM

更新日期：2013-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review looks at what is currently known about liver disease in cystic fibrosis (CF) in light of the literature over the past year, and what the ongoing challenges are from a clinical and research perspective for the optimal management of cystic fibrosis liver disease (CFLD). RECENT FINDINGS:Pati...

journal_title：Current opinion in pulmonary medicine

authors： Rowland M,Bourke B

更新日期：2011-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the current understanding and clinical applicability of severity scoring systems in pneumonia management. RECENT FINDINGS:Severity scores in community-acquired pneumonia are strong markers of mortality, but are not necessarily clinical decision-aid tools. The use of severity scores to sup...

journal_title：Current opinion in pulmonary medicine

authors： Ranzani OT,Taniguchi LU,Torres A

更新日期：2018-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This article aims to review the geological background of environmental asbestos exposure and the distribution of asbestos-related disease (ARD) in association with naturally occurring asbestos (NOA), and discusses the potential health risks associated with exposure to non-occupational asbestos. RECEN...

journal_title：Current opinion in pulmonary medicine

authors： Bayram M,Bakan ND

更新日期：2014-05-01 00:00:00

abstract：PURPOSE OF REVIEW:A relatively new class of CD4 expressing T cells that also express and release interleukin-17 (Th17 cells) is gaining attention based on their capacity to regulate inflammatory responses in a spectrum of chronic autoimmune diseases. The purpose of this review is to consider recent studies relating to ...

journal_title：Current opinion in pulmonary medicine

authors： Crouser ED

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to provide an update on the diagnosis and classification of interstitial lung disease (ILD), with a specific focus on newly described ILD subtypes and phenotypes. In addition, the strengths and limitations of the current approach to ILD diagnosis and management are discus...

journal_title：Current opinion in pulmonary medicine

authors： Ryerson CJ,Collard HR

更新日期：2013-09-01 00:00:00

abstract：:The most common syndromes associated with obstructive lung disease are asthma and chronic obstructive pulmonary disease (COPD). Evidence for a viral etiology of asthmatic exacerbations is well known, but evidence for a role for viruses in COPD exacerbation is just emerging. Viruses may cause chronic infection in both ...

journal_title：Current opinion in pulmonary medicine

authors： Seemungal TA,Wedzicha JA

更新日期：2003-03-01 00:00:00

abstract：:Thoracoscopy has received increasing attention over the past decade as a result of the considerable advances that have been made in the development of endoscopic instruments. In contrast to the newly established video-assisted thoracoscopic surgery, the classic way to perform thoracoscopy is using only local anesthesi...

journal_title：Current opinion in pulmonary medicine

authors： Loddenkemper R,Schönfeld N

更新日期：1998-07-01 00:00:00

abstract：:Wheezing in infants and children presents a difficult differential diagnosis contingent on the presenting symptoms and age of the child. A determination of the anatomy of the lower airway, combined with allergic, infectious, and noninfectious irritants, is requisite to a complete evaluation. The intervention strategie...

journal_title：Current opinion in pulmonary medicine

authors： Chipps BE,Chipps DR

更新日期：1999-01-01 00:00:00

abstract：:Diabetes is a common complication of cystic fibrosis. Because it is associated with increased morbidity and mortality, prompt diagnosis and aggressive management of cystic fibrosis-related diabetes is important. The Cystic Fibrosis Foundation held a consensus conference in 1998 to define the standards of care for pati...

journal_title：Current opinion in pulmonary medicine

authors： Riggs AC,Seaquist ER,Moran A

更新日期：1999-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Summarize recently published studies and critiques evaluating the effects of the American Academy of Sleep Medicine (AASM) Sleep Scoring Manual. RECENT FINDINGS:Only a few retrospective studies have been published evaluating the new AASM Scoring Manual. These have shown that when scoring polysomnogra...

journal_title：Current opinion in pulmonary medicine

authors： Grigg-Damberger MM

更新日期：2009-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Survival for patients with cystic fibrosis (CF) continues to improve. The proportion of CF patients over the age of 18 years is nearly 50%, and care providers will need to better understand this patient population. Despite these improvements, young females continue to have a worse prognosis and lower ...

journal_title：Current opinion in pulmonary medicine

authors： McIntyre K

更新日期：2013-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Dornase alfa (Pulmozyme) is one of the most commonly used medications to treat the lung disease of cystic fibrosis (CF). As other respiratory medications have entered the clinical market, understanding the proper use and indication for dornase alfa is increasingly important. In addition, dornase alfa ...

journal_title：Current opinion in pulmonary medicine

authors： Wagener JS,Kupfer O

更新日期：2012-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Global climate change and population explosion leading to changes in natural ecosystem and travel across the continents have resulted in an increase in the transmission of parasites to human beings. This review focuses on recent advancements in parasitic lung infections. RECENT FINDINGS:Invasive para...

journal_title：Current opinion in pulmonary medicine

authors： Vijayan VK

更新日期：2009-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The role of thoracic surgery in pulmonary tuberculosis, in either a diagnostic or a therapeutic role, is well established. This review aims to underline the current indications for lung resection, surgical strategy and outcomes associated with surgery. RECENT FINDINGS:There has been a renewed interes...

journal_title：Current opinion in pulmonary medicine

authors： Naidoo R

更新日期：2008-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients with lung cancer are particularly vulnerable to lung injury associated with immune checkpoint inhibition and often present with more frequent and more severe manifestations of lung disease compared to patients with other tumor types. The present review explores the reasons for increased susce...

journal_title：Current opinion in pulmonary medicine

authors： Shannon VR

更新日期：2020-07-01 00:00:00

abstract：PURPOSE OF REVIEW:After 'curative' resection, many patients are still at risk for further lung cancer, either as a recurrence or a new metachronous primary. In theory, close follow-up should improve survival by catching relapse early - but in reality, many experts feel that surveillance for recurrence is of uncertain v...

journal_title：Current opinion in pulmonary medicine

authors： Chang CF,Gould M

更新日期：2017-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) is caused by a mixture of small airway disease (obstructive bronchitis) and parenchymal lung tissue destruction (emphysema). The relative contributions of these two pathologic states vary from person to person. Having the ability to phenotype patients into ...

journal_title：Current opinion in pulmonary medicine

authors： Stewart JI,Criner GJ

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This article explains the high comorbidity of craniofacial pain (chronic face pain, temporomandibular disorders, and primary headaches) with obstructive sleep breathing disorders and obstructive sleep apnea (OSA). It is recommended that physicians treating OSA should be aware of the concurrent chronic...

journal_title：Current opinion in pulmonary medicine

authors： Olmos SR

更新日期：2016-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Pulmonary cystic echinococcosis, a zoonosis caused by the larvae of the dog tapeworm Echinococcus granulosus, is considered as a major public health problem in countries where dogs are used to care for large herds. Despite its frequency and widespread endemicity, the literature on pulmonary cystic ech...

journal_title：Current opinion in pulmonary medicine

authors： Santivanez S,Garcia HH

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Secondary spontaneous pneumothorax (SSP) can occur in patients who are suffering from diffuse lung disease. The main cause of SSP is chronic obstructive pulmonary disease (COPD). In contrast to primary spontaneous pneumothorax, SSP is a potentially life-threatening condition because patients with SSP ...

journal_title：Current opinion in pulmonary medicine

authors： Nakajima J

更新日期：2010-07-01 00:00:00

abstract：:One aim of caring for adults and children with asthma should be the identification and treatment of the functional impairments that are troublesome to these patients in their daily lives. Studies have shown that correlations between measures of clinical asthma severity and control and health-related quality of life (H...

journal_title：Current opinion in pulmonary medicine

authors： Juniper EF

更新日期：1999-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Telomere attrition has been proposed as one of the aging hallmarks in pulmonary fibrosis. Telomere shortening and telomerase gene mutations have been widely evaluated in recent years. Reduced telomere length may be identified in a quarter of patients with sporadic idiopathic pulmonary fibrosis (IPF) a...

journal_title：Current opinion in pulmonary medicine

authors： Molina-Molina M,Borie R

更新日期：2018-09-01 00:00:00