Hypersensitivity pneumonitis.

abstract：:Pulmonary embolism occurs in more than 175,000 patients each year in the United States. The objectives of treatment are to prevent death from the existing embolus, to prevent death and morbidity from recurrent pulmonary embolism, and to prevent morbidity from recurrent deep-vein thrombosis. For patients with adequate ...

journal_title：Current opinion in pulmonary medicine

authors： Raskob GE

更新日期：1999-07-01 00:00:00

abstract：:Patients infected with HIV are at risk of developing a variety of infectious and malignant pleuropulmonary disorders. The three most common causes of AIDS-related pleural effusions are parapneumonic effusions or empyemas, tuberculosis, and Kaposi's sarcoma. However, the relative frequency of these conditions varies fr...

journal_title：Current opinion in pulmonary medicine

authors： Hamm H,Matthys H

更新日期：1997-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Pulmonary hypertension has been reported to complicate the course of a number of fibrotic lung diseases, including idiopathic pulmonary fibrosis, chronic hypersensitivity pneumonitis and nonspecific interstitial pneumonitis. Most commonly, mild elevations in the mean pulmonary artery pressure are seen...

journal_title：Current opinion in pulmonary medicine

authors： King CS,Nathan SD

更新日期：2019-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The objective is to discuss recent progress in our understanding of the role of the indoor environment in asthma, focusing on the special role of cat allergens. RECENT FINDINGS:Sensitization to Fel d 1 is the dominant event in inhalant responses to cat; however, there are also IgE responses to the li...

journal_title：Current opinion in pulmonary medicine

authors： Kelly LA,Erwin EA,Platts-Mills TA

更新日期：2012-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent work demonstrates that patients with refractory asthma are likely to be sensitized to environmental fungi and that specific antifungal treatments may be of benefit to this group. RECENT FINDINGS:The relationships among fungal sensitization, exposure and asthma severity are imperfectly understo...

journal_title：Current opinion in pulmonary medicine

authors： Gore RB

更新日期：2010-01-01 00:00:00

abstract：:Interstitial lung diseases are characterized by disruption of the distal pulmonary parenchyma. The clinical history manifestations, cough and dyspnea, and physical exam manifestations, inspiratory crackles, are nonspecific. Pulmonary function testing aids in the evaluation and management of patients with interstitial ...

journal_title：Current opinion in pulmonary medicine

authors： Flaherty KR,Martinez FJ

更新日期：2000-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma is a heterogeneous disorder presenting with many phenotypes. Precise phenotypic definition has eluded the medical research community for years, despite recognition of different disease subtypes. Improved phenotypic characterization and knowledge of underlying pathobiology is necessary for linka...

journal_title：Current opinion in pulmonary medicine

authors： Kiley J,Smith R,Noel P

更新日期：2007-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Treatment of hepatic hydrothorax is challenging because of its rapid symptomatic recurrence. This review will focus on potential therapeutic approaches to hepatic hydrothorax. RECENT FINDINGS:Hepatic hydrothorax is refractory to salt restriction and diuretics in approximately 25% of cases. Primary ma...

journal_title：Current opinion in pulmonary medicine

authors： Porcel JM

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Smoking is a major risk factor for lung cancer, which is the leading cause of cancer-related deaths both in the USA and worldwide. Chronic obstructive pulmonary disease and emphysema are comorbid conditions often found in lung cancer patients. The inflammatory pathways that link chronic obstructive pu...

journal_title：Current opinion in pulmonary medicine

authors： Lee G,Walser TC,Dubinett SM

更新日期：2009-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize recent advances in our understanding of the impact sleep disturbances have on our health, with particular focus on the brain. The present review considers the influence of sleep disturbance on the neurovascular unit; the role of sleep disturbance in neurodege...

journal_title：Current opinion in pulmonary medicine

authors： Aguirre CC

更新日期：2016-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews current data on pathophysiologic mechanisms by which sleep-disordered breathing during pregnancy may cause harm, and explores biological pathways for associated adverse maternal and fetal outcomes, especially pregnancy-induced hypertension and gestational diabetes. RECENT FINDING...

journal_title：Current opinion in pulmonary medicine

authors： Izci-Balserak B,Pien GW

更新日期：2010-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients with lung cancer are particularly vulnerable to lung injury associated with immune checkpoint inhibition and often present with more frequent and more severe manifestations of lung disease compared to patients with other tumor types. The present review explores the reasons for increased susce...

journal_title：Current opinion in pulmonary medicine

authors： Shannon VR

更新日期：2020-07-01 00:00:00

abstract：:Some time ago, the Th2 cytokine, interleukin (IL)-13, was identified as a critical regulator of the allergic response. Initial studies in animal models of disease provided compelling evidence that IL-13, independent from other Th2 cytokines, was necessary and sufficient to induce all features of allergic asthma. This ...

journal_title：Current opinion in pulmonary medicine

authors： Wills-Karp M,Chiaramonte M

更新日期：2003-01-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, we describe the 'state-of-the-art' in our knowledge of asthma and what gaps exist, which can be exploited in the future for effective translation of our knowledge from the bench or population studies to diagnosis and therapy. RECENT FINDINGS:The advent of microbiome research has expan...

journal_title：Current opinion in pulmonary medicine

authors： Brar T,Nagaraj S,Mohapatra S

更新日期：2012-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Since the introduction especially of multidetector computed tomography scanners, detection of peripheral pulmonary nodules as small as 2-3 mm is now a frequent event even in individuals without a significant smoking history. This preponderance of small indeterminate nodules has necessitated reconsider...

journal_title：Current opinion in pulmonary medicine

authors： Shiau MC,Bonavita J,Naidich DP

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review was to evaluate the consequence of obstructive sleep apnea (OSA) in pulmonary hypertension by reviewing the current literature and understanding potential pathophysiological mechanisms. RECENT FINDINGS:Small studies have suggested a high prevalence of comorbid OSA in those ...

journal_title：Current opinion in pulmonary medicine

authors： Minic M,Ryan CM

更新日期：2015-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Although currently available drugs to treat asthma are effective in most patients, a proportion of patients do not respond or experience side-effects; which is partly genetically determined. Pharmacogenetics is the study of how genetic variations influence drug response. In this review, we summarize p...

journal_title：Current opinion in pulmonary medicine

authors： Kersten ET,Koppelman GH

更新日期：2017-01-01 00:00:00

abstract：:The progressive breakdown of the cell-mediated immunity, which characterizes the natural history of HIV infection, invariably leads to the development of miscellaneous opportunistic infections or neoplasms involving a number of tissues, including the respiratory tract. In particular, given the extent and the severity ...

journal_title：Current opinion in pulmonary medicine

authors： Semenzato G,Agostini C

更新日期：1995-09-01 00:00:00

abstract：:The bacillary population described in tuberculous pleuritis is small, and its most likely pathogenetic mechanism is essentially immunologic. This explains why, until now, the diagnostic identification of tuberculous pleuritis (TP) has been based on the presence of granulomas in pleural biopsy. Correcting this diagnost...

journal_title：Current opinion in pulmonary medicine

authors： Pérez-Rodriguez E,Jiménez Castro D

更新日期：2000-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Lung cancer is the leading cause of cancer mortality in men and women. Most patients present with advanced disease and face significant morbidity, with many reporting distressing symptoms throughout the course of their illness. The purpose of this review is to highlight the recent studies that support...

journal_title：Current opinion in pulmonary medicine

authors： Shin J,Temel J

更新日期：2013-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Malignant pleural effusion (MPE) poses a common and significant clinical problem. Its pathogenesis is poorly understood and therapeutic options are limited. Herein are summarized animal models of MPE and their contributions in unveiling new aspects of the pathobiology of the condition. RECENT FINDING...

journal_title：Current opinion in pulmonary medicine

authors： Stathopoulos GT,Kalomenidis I

更新日期：2009-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article is to review recent observations in the area of infectious lung complications in individuals with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). Since the immunodeficiency was first characterized, it has been associated with enhanced susceptibilit...

journal_title：Current opinion in pulmonary medicine

authors： Boyton RJ

更新日期：2005-05-01 00:00:00

abstract：:Corticosteroids were the mainstay of therapy for idiopathic pulmonary fibrosis (IPF) for more than four decades, but their efficacy is unproven and toxicities are substantial. The course of IPF is characterized by progressive respiratory insufficiency, leading to death within 3 to 8 years from the onset of symptoms. A...

journal_title：Current opinion in pulmonary medicine

authors： Lynch JP 3rd,White E,Flaherty K

更新日期：2001-09-01 00:00:00

abstract：:Lung cancer is the leading cause of cancer-related death worldwide. For patients diagnosed with early-stage lung cancer, complete surgical resection remains the best hope for cure. Limited resections are avoided when possible because of higher recurrence rates and potentially worse long-term survival. Traditionally, a...

journal_title：Current opinion in pulmonary medicine

authors： Moffatt SD,Mitchell JD,Whyte RI

更新日期：2002-07-01 00:00:00

abstract：:Acute bronchitis in previously fit individuals is a common condition that is usually mild and self limiting. Chronic bronchitis remains a common cause of morbidity and mortality, and the cost to the nation due to lost working days and to health services is enormous. Cigarette smoking is the major etiologic factor, alt...

journal_title：Current opinion in pulmonary medicine

authors： Wilson R,Rayner CF

更新日期：1995-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Exacerbations of asthma in children are most frequently precipitated by respiratory infections with a seasonal pattern. However, management takes little account of the underlying infective or other precipitant abnormality. RECENT FINDINGS:Interactions between environmental triggers, the airway microb...

journal_title：Current opinion in pulmonary medicine

authors： Cook J,Saglani S

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Adherence to asthma therapies is poor leading to unnecessary morbidity and increased use of emergency and hospital resources. Strategies to improve adherence have not been successful. RECENT FINDINGS:Asthma adherence disease management is a clinical method to improve adherence for asthma patients. Th...

journal_title：Current opinion in pulmonary medicine

authors： Weinstein AG

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Telomere attrition has been proposed as one of the aging hallmarks in pulmonary fibrosis. Telomere shortening and telomerase gene mutations have been widely evaluated in recent years. Reduced telomere length may be identified in a quarter of patients with sporadic idiopathic pulmonary fibrosis (IPF) a...

journal_title：Current opinion in pulmonary medicine

authors： Molina-Molina M,Borie R

更新日期：2018-09-01 00:00:00

abstract：:Apoptosis, also known as activation-induced cell death or programmed cell death, is an active suicide mechanism that is involved in normal tissue turnover during embryogenesis and adult life. There are many examples of apoptosis in the immune system, including programmed cell death of T cells during negative intrathym...

journal_title：Current opinion in pulmonary medicine

authors： Agostini C,Perin A,Semenzato G

更新日期：1998-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Glucocorticosteroids (GCSs) remain the cornerstone of therapy for treating the inflammatory component of asthma. Clinical response to GCS is heterogeneous, varying both within asthma 'endotypes', as well as the same individual. Different factors and micro-environment can alter the canonical GCS-induce...

journal_title：Current opinion in pulmonary medicine

authors： Mukherjee M,Svenningsen S,Nair P

更新日期：2017-01-01 00:00:00