The utility of antifungal agents for asthma.

abstract：PURPOSE OF REVIEW:Common variable immunodeficiency (CVID) is the most common primary immunodeficiency characterized by a deficiency of immunoglobulins. Approximately 30% of the patients develop autoimmune and granulomatous disease. Similar to sarcoidosis, granulomatous disease in CVID can potentially affect all organs,...

journal_title：Current opinion in pulmonary medicine

authors： Prasse A,Kayser G,Warnatz K

更新日期：2013-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Exacerbations of asthma in children are most frequently precipitated by respiratory infections with a seasonal pattern. However, management takes little account of the underlying infective or other precipitant abnormality. RECENT FINDINGS:Interactions between environmental triggers, the airway microb...

journal_title：Current opinion in pulmonary medicine

authors： Cook J,Saglani S

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Matrix metalloproteinases (MMPs) are a family of over 20 zinc-dependent proteases with different biological and pathological activities, and many have been implicated in several diseases. Although nonselective MMP inhibitors are known to induce serious side-effects, targeting individual MMPs may offer...

journal_title：Current opinion in pulmonary medicine

authors： Abd-Elaziz K,Jesenak M,Vasakova M,Diamant Z

更新日期：2021-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights recent developments in liver disease associated with cystic fibrosis. RECENT FINDINGS:The broad spectrum of hepatobiliary problems in cystic fibrosis includes specific alterations ascribable to the underlying defect as well as lesions of iatrogenic origin or that reflect the ef...

journal_title：Current opinion in pulmonary medicine

authors： Colombo C

更新日期：2007-11-01 00:00:00

abstract：:Although it had been appreciated that high levels of antituberculous drug resistance existed in some regions of the world, the full extent of the problem was not known. A combined initiative by the World Health Organization and the International Union Against Tuberculosis and Lung Disease was launched in 1994 to addre...

journal_title：Current opinion in pulmonary medicine

authors： Willcox PA

更新日期：2001-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine recent reports of serosal involvement in sarcoidosis. RECENT FINDINGS:Peritoneal sarcoidosis continues to be a rare manifestation of the disease. Patients with peritoneal disease tend to be women between the ages of 20 and 40 years, and most commonly present with ascites and abdominal pain...

journal_title：Current opinion in pulmonary medicine

authors： Iyer S,Afshar K,Sharma OP

更新日期：2008-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Glucocorticosteroids (GCSs) remain the cornerstone of therapy for treating the inflammatory component of asthma. Clinical response to GCS is heterogeneous, varying both within asthma 'endotypes', as well as the same individual. Different factors and micro-environment can alter the canonical GCS-induce...

journal_title：Current opinion in pulmonary medicine

authors： Mukherjee M,Svenningsen S,Nair P

更新日期：2017-01-01 00:00:00

abstract：:Patients with acute deep vein thrombosis (DVT) were treated with a body-weight independent dosage of 2 x 8000 aXa IU low-molecular-weight heparin (LMWH) Certoparin. After the subcutaneous administration of 8000 IU Certoparin, pharmacodynamic parameters did not differ between patients and healthy volunteers, and the AU...

journal_title：Current opinion in pulmonary medicine

authors： Harenberg J

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Medical thoracoscopy provides the physician a window into the pleural space. The procedure allows biopsy of the parietal pleura under direct visualization with good accuracy. In addition, it achieves therapeutic goals of fluid drainage, guided chest tube placement, and pleurodesis. RECENT FINDINGS:Co...

journal_title：Current opinion in pulmonary medicine

authors： Lee P,Mathur PN

更新日期：2016-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) imposes a large burden on the global population and even more so for the elderly who face significant obstacles in the diagnosis, management, and psychosocial effects of the disease. This review describes the current challenges and key points in the managem...

journal_title：Current opinion in pulmonary medicine

authors： Allen B,Aboussouan LS

更新日期：2021-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The review highlights the clinical findings and the management of community-acquired, health-care associated and nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA). RECENT FINDINGS:Although previously considered as a purely nosocomial event, community-acquired MRSA pneumon...

journal_title：Current opinion in pulmonary medicine

authors： Tacconelli E,De Angelis G

更新日期：2009-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article is to review recent observations in the area of infectious lung complications in individuals with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). Since the immunodeficiency was first characterized, it has been associated with enhanced susceptibilit...

journal_title：Current opinion in pulmonary medicine

authors： Boyton RJ

更新日期：2005-05-01 00:00:00

abstract：:Antibiotic resistance in respiratory pathogens has dramatically increased during recent years. Resistance to penicillin and multiple antimicrobial agents in pneumococci and resistance to ampicillin in Moraxella catarrhalis and Haemophilus influenzae, as a result of betalactamase production, have become highly prevalen...

journal_title：Current opinion in pulmonary medicine

authors： Dominguez MA,Pallares R

更新日期：1998-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article is to examine the evidence for the effectiveness of systemic corticosteroids in managing acute asthma in children as it relates to the timing of its administration. RECENT FINDINGS:Three themes relevant to the timing of systemic corticosteroid administration as it relates to m...

journal_title：Current opinion in pulmonary medicine

authors： Bhogal SK

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Subsequent to the ATS/ERS consensus classification of idiopathic interstitial pneumonia, non-specific interstitial pneumonia pattern was the dominant pattern in many collagen vascular diseases, which may explain the better prognosis of interstitial pneumonia associated with collagen disease than idiop...

journal_title：Current opinion in pulmonary medicine

authors： Kim DS

更新日期：2006-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This article aims to review the most recent proteomic findings in tissue and biological fluids and application of new technologies for the study of interstitial lung diseases. RECENT FINDINGS:New insights into lung cell biology as well as novel pathogenetic pathways of different interstitial lung dis...

journal_title：Current opinion in pulmonary medicine

authors： Rottoli P,Bargagli E,Landi C,Magi B

更新日期：2009-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Although currently available drugs to treat asthma are effective in most patients, a proportion of patients do not respond or experience side-effects; which is partly genetically determined. Pharmacogenetics is the study of how genetic variations influence drug response. In this review, we summarize p...

journal_title：Current opinion in pulmonary medicine

authors： Kersten ET,Koppelman GH

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Minimally invasive diagnostic strategies for pulmonary embolism are in constant evolution, integrating new diagnostic tools along with the better use of clinical information. RECENT FINDINGS:In the past year, several reports have provided more data on the value of clinical signs and symptoms for diag...

journal_title：Current opinion in pulmonary medicine

authors： Le Gal G,Perrier A

更新日期：2006-09-01 00:00:00

abstract：PURPOSE OF REVIEW:A small percentage of asthma exacerbations are linked with infection by an atypical bacterium, such as Chlamydia pneumoniae or Mycoplasma pneumoniae. These bacteria also have been proposed to cause occult chronic lower airway inflammation and to initiate nonatopic asthma in adults. Consequently, the l...

journal_title：Current opinion in pulmonary medicine

authors： Cazzola M,Matera MG,Blasi F

更新日期：2004-01-01 00:00:00

abstract：PURPOSE OF REVIEW:There has been much recent interest in the use of macrolide antibiotics as chronic suppressive therapy in patients with cystic fibrosis. Three recent randomized, placebo-controlled trials have been conducted. RECENT FINDINGS:All three trials used similar regimens of azithromycin, and lung function im...

journal_title：Current opinion in pulmonary medicine

authors： Saiman L

更新日期：2004-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews current data on pathophysiologic mechanisms by which sleep-disordered breathing during pregnancy may cause harm, and explores biological pathways for associated adverse maternal and fetal outcomes, especially pregnancy-induced hypertension and gestational diabetes. RECENT FINDING...

journal_title：Current opinion in pulmonary medicine

authors： Izci-Balserak B,Pien GW

更新日期：2010-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Obstructive sleep apnea (OSA) is heterogeneous in terms of contributing pathophysiological mechanisms, clinical presentation, and consequences. Different study models from animal models of intermittent hypoxia over case-control, cohort, and population-based observational studies to uncontrolled interv...

journal_title：Current opinion in pulmonary medicine

authors： Schwarz EI

更新日期：2019-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Historically, pleural effusions have been attributed to a single cause. There is growing recognition that a substantial proportion of pleural effusions may have more than one underlying cause. The purpose of this review is to summarise recent findings regarding the diagnosis and treatment of effusions...

journal_title：Current opinion in pulmonary medicine

authors： Walker S,Maskell N

更新日期：2017-07-01 00:00:00

abstract：:Lung volume reduction surgery (LVRS) is a palliative surgical procedure for patients with severe emphysema. Resection of nonfunctional emphysematous lung tissue has been reported to relieve breathlessness and to improve quality of life for many patients by improving lung elastic recoil, respiratory muscle function, an...

journal_title：Current opinion in pulmonary medicine

authors： Meyer KC,Cornwell RD,Love RB

更新日期：2000-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma is a heterogeneous disorder presenting with many phenotypes. Precise phenotypic definition has eluded the medical research community for years, despite recognition of different disease subtypes. Improved phenotypic characterization and knowledge of underlying pathobiology is necessary for linka...

journal_title：Current opinion in pulmonary medicine

authors： Kiley J,Smith R,Noel P

更新日期：2007-01-01 00:00:00

abstract：PURPOSE OF REVIEW:After 'curative' resection, many patients are still at risk for further lung cancer, either as a recurrence or a new metachronous primary. In theory, close follow-up should improve survival by catching relapse early - but in reality, many experts feel that surveillance for recurrence is of uncertain v...

journal_title：Current opinion in pulmonary medicine

authors： Chang CF,Gould M

更新日期：2017-07-01 00:00:00

abstract：PURPOSE OF REVIEW:In the past few years, there have been exciting developments in bronchoscopic efforts at attaining lung volume reduction (LVR), given real and perceived risks of surgical LVR. The purpose of this review is to discuss these techniques, with special emphasis on what we have learnt in the past 1-2 years....

journal_title：Current opinion in pulmonary medicine

authors： Taneja A

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Accurate diagnosis of interstitial lung diseases (ILDs) can be challenging, and a substantial percentage of ILD patients remain unclassifiable even after thorough assessment by an experienced multidisciplinary team. In this review, we summarize the recent literature on the definition, prevalence, diag...

journal_title：Current opinion in pulmonary medicine

authors： Guler SA,Ryerson CJ

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Spontaneous hemopneumothorax can be life threatening, and is a cause of patients presenting with unexplained signs of significant hypovolemia. The debate relating to patient selection and timing of surgery in patients with spontaneous hemopneumothorax remains unresolved. RECENT FINDINGS:Our experienc...

journal_title：Current opinion in pulmonary medicine

authors： Ng CSh,Yim AP

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines the associations between chronic obstructive pulmonary disease (COPD) and renal and hepatobiliary diseases, with emphasis on the epidemiology and clinical outcomes, along with current information on pathophysiologic mechanisms and risk factors. RECENT FINDINGS:Glomerular filtrati...

journal_title：Current opinion in pulmonary medicine

authors： Mapel D

更新日期：2014-03-01 00:00:00