Identification and management of pleural effusions of multiple aetiologies.

Abstract:

PURPOSE OF REVIEW:Historically, pleural effusions have been attributed to a single cause. There is growing recognition that a substantial proportion of pleural effusions may have more than one underlying cause. The purpose of this review is to summarise recent findings regarding the diagnosis and treatment of effusions secondary to more than one aetiology. RECENT FINDINGS:A recent prospective study identified that 30% of pleural effusions had more than one underlying aetiology. With a rising prevalence of cardiovascular and malignant disease, the incidence of the complex pleural patient is increasing. The use of biomarkers, including pro-B-type natriuretic peptide, have been suggested as a way of identifying contributing disease process. SUMMARY:Understanding that there are potentially concurrent causes to a pleural effusion is vital in establishing the diagnoses of multiple underlying aetiologies. New diagnostic pathways, with increasing use of biomarkers, will be required to identify the complex pleural effusion. Further studies on whether the targeting of separate aetiologies improves outcomes will help develop future management strategies.

journal_name

Curr Opin Pulm Med

authors

Walker S,Maskell N

doi

10.1097/MCP.0000000000000388

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

339-345

issue

4

eissn

1070-5287

issn

1531-6971

journal_volume

23

pub_type

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