Contemporary approach to the diagnosis of non-massive pulmonary embolism.

Abstract:

PURPOSE OF REVIEW:Minimally invasive diagnostic strategies for pulmonary embolism are in constant evolution, integrating new diagnostic tools along with the better use of clinical information. RECENT FINDINGS:In the past year, several reports have provided more data on the value of clinical signs and symptoms for diagnosing pulmonary embolism and improved clinical prediction rules for pulmonary embolism. Among the diagnostic tools, the use of multislice computed tomography of the chest received further validation, whereas the yield of bedside tests, such as the D-dimer test or alveolar dead-space measurement, have been further investigated. Furthermore, data linking good outcomes with appropriate diagnostic strategies in patients with suspected pulmonary embolism were reported this year for the first time. SUMMARY:These new data allow a more evidence-based and cost-effective approach to patients with suspected non-massive pulmonary embolism. Multislice computed tomography is replacing other imaging tests. More research should be performed on the role of lower limb venous compression ultrasonography, and on how to select patients in whom pulmonary embolism should be suspected and investigated.

journal_name

Curr Opin Pulm Med

authors

Le Gal G,Perrier A

doi

10.1097/01.mcp.0000239542.32455.9f

subject

Has Abstract

pub_date

2006-09-01 00:00:00

pages

291-8

issue

5

eissn

1070-5287

issn

1531-6971

pii

00063198-200609000-00003

journal_volume

12

pub_type

杂志文章,评审
  • Intrathoracic neoplasms other than bronchogenic carcinoma.

    abstract::Intrathoracic neoplasms other than bronchogenic carcinoma comprise a disparate group of tumors that have in common an anatomic location within the thorax. For the purposes of this review, they are divided into three categories: pulmonary metastases from locations other than the thorax, mediastinal neoplasms, and unusu...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-199707000-00004

    authors: Yoneda KY,Tharratt RS

    更新日期:1997-07-01 00:00:00

  • Computed tomographic imaging of bronchiolar disorders.

    abstract::The bronchiolitides can be categorized broadly as constrictive or proliferative, each with characteristic CT features. The cardinal CT signs of constrictive bronchiolitis are mosaic perfusion, enhanced on expiratory CT scan and variably associated with bronchiectasis and, less frequently, centrilobular branching struc...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-199803000-00005

    authors: Wells AU

    更新日期:1998-03-01 00:00:00

  • Asthma phenotypes and endotypes.

    abstract:PURPOSE OF REVIEW:It is increasingly clear that asthma is not a single disease, but a disorder with vast heterogeneity in pathogenesis, severity, and treatment response. In this review, we discuss the present understanding of different asthma phenotypes and endotypes, and the prospects of personalized medicine for asth...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e32835b10ec

    authors: Lin TY,Poon AH,Hamid Q

    更新日期:2013-01-01 00:00:00

  • The AASM scoring manual: a critical appraisal.

    abstract:PURPOSE OF REVIEW:Summarize recently published studies and critiques evaluating the effects of the American Academy of Sleep Medicine (AASM) Sleep Scoring Manual. RECENT FINDINGS:Only a few retrospective studies have been published evaluating the new AASM Scoring Manual. These have shown that when scoring polysomnogra...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e328331a2bf

    authors: Grigg-Damberger MM

    更新日期:2009-11-01 00:00:00

  • Upper respiratory tract infections.

    abstract::In reviewing recent advances in upper respiratory tract infections, we focus on five key topics. First, the use of ribavirin in the treatment of respiratory syncytial virus infection has been limited to the immunosuppressed. Prophylaxis in high-risk patients with specific immunoglobulin is effective and a new monoclon...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-199905000-00006

    authors: Moore DA,Sharland M,Friedland JS

    更新日期:1999-05-01 00:00:00

  • Adenosine signaling in asthma and chronic obstructive pulmonary disease.

    abstract:PURPOSE OF REVIEW:The chronic lung diseases, asthma and chronic obstructive pulmonary disease, are pulmonary disorders in which persistent inflammation and alterations in lung structure contribute to a progressive loss of lung function. Although the exact type of inflammation and damage in each disease is distinct, the...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.mcp.0000199002.46038.cb

    authors: Mohsenin A,Blackburn MR

    更新日期:2006-01-01 00:00:00

  • Improving adherence to asthma medications: current knowledge and future perspectives.

    abstract:PURPOSE OF REVIEW:Poor adherence to asthma controller medications, particularly inhaled corticosteroids, has been well known for decades and is a major cause of uncontrolled asthma and increased healthcare utilization. This review presents recent evidence on factors leading to nonadherence in specific age groups, paren...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000334

    authors: Blake KV

    更新日期:2017-01-01 00:00:00

  • Innate immunity in sarcoidosis pathobiology.

    abstract:PURPOSE OF REVIEW:The immunopathogenesis of sarcoidosis is considered to involve contributions from both adaptive and innate immune responses. Although the identification of adaptive responses to candidate pathogenic antigens will elucidate mechanisms that regulate inflammation in sarcoidosis, innate mechanisms likely ...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000305

    authors: Chen ES

    更新日期:2016-09-01 00:00:00

  • Advances in radiology for interstitial lung disease.

    abstract::Recently, with radiology some advances have been made in the care of patients with interstitial lung disease, predominately through the use of high-resolution computed tomography. This technique is helpful not only in the diagnosis of interstitial lung disease, but also in patient follow-up and management. Other techn...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章

    doi:10.1097/00063198-199909000-00002

    authors: Wilcox AG

    更新日期:1999-09-01 00:00:00

  • Severity scoring systems for pneumonia: current understanding and next steps.

    abstract:PURPOSE OF REVIEW:To describe the current understanding and clinical applicability of severity scoring systems in pneumonia management. RECENT FINDINGS:Severity scores in community-acquired pneumonia are strong markers of mortality, but are not necessarily clinical decision-aid tools. The use of severity scores to sup...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000468

    authors: Ranzani OT,Taniguchi LU,Torres A

    更新日期:2018-05-01 00:00:00

  • Newer antibiotics for the treatment of respiratory tract infections.

    abstract:PURPOSE OF REVIEW:In this review, we highlight some of the developments achieved over the past 2 years in the field of novel antimicrobial compounds. RECENT FINDINGS:Modification of existing compound classes to create more powerful compounds capable of overcoming pathogen resistance and the introduction of completely ...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-200405000-00008

    authors: Blasi F,Tarsia P,Cosentini R,Valenti V

    更新日期:2004-05-01 00:00:00

  • Choosing a nebulizer for cystic fibrosis applications.

    abstract::As the number of inhaled drugs available for cystic fibrosis grows, there is increasing awareness of delivery device issues. Current jet and ultrasonic nebulizers are inefficient at delivering drugs to the lower respiratory tract. There are large differences in output characteristics between nebulizers and high inters...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-199711000-00005

    authors: Geller DE

    更新日期:1997-11-01 00:00:00

  • Revisiting matrix metalloproteinase 12: its role in pathophysiology of asthma and related pulmonary diseases.

    abstract:PURPOSE OF REVIEW:Matrix metalloproteinases (MMPs) are a family of over 20 zinc-dependent proteases with different biological and pathological activities, and many have been implicated in several diseases. Although nonselective MMP inhibitors are known to induce serious side-effects, targeting individual MMPs may offer...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000743

    authors: Abd-Elaziz K,Jesenak M,Vasakova M,Diamant Z

    更新日期:2021-01-01 00:00:00

  • Significance of obstructive sleep apnea in the patient with pulmonary hypertension.

    abstract:PURPOSE OF REVIEW:The purpose of this review was to evaluate the consequence of obstructive sleep apnea (OSA) in pulmonary hypertension by reviewing the current literature and understanding potential pathophysiological mechanisms. RECENT FINDINGS:Small studies have suggested a high prevalence of comorbid OSA in those ...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000206

    authors: Minic M,Ryan CM

    更新日期:2015-11-01 00:00:00

  • Surgery for chronic obstructive pulmonary disease: the place for lung volume reduction and transplantation.

    abstract::Lung volume reduction surgery and lung transplantation have been shown to improve lung function, exercise capacity, and quality of life in patients with advanced emphysema. Because the indications for both surgical procedures overlap, lung volume reduction surgery may be used as an alternative treatment or as a "bridg...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-200103000-00007

    authors: Cordova FC,Criner GJ

    更新日期:2001-03-01 00:00:00

  • Prognosis in cystic fibrosis.

    abstract::Prognosis for patients with cystic fibrosis has improved dramatically over the past three decades. In the United States, median survival age is now 28.9 years. Although genotype predicts exocrine pancreatic function, it does not correlate with pulmonary status or overall clinical outcome. However, there are a number o...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-199511000-00003

    authors: Rosenstein BJ,Zeitlin PL

    更新日期:1995-11-01 00:00:00

  • Serologic evaluation in idiopathic interstitial pneumonias.

    abstract:PURPOSE OF REVIEW:Diagnosis of idiopathic interstitial pneumonias (IIPs) requires the exclusion of, among others, concomitant connective tissue diseases (CTDs), which may present as interstitial lung disease (ILD). This review focuses on the evaluation required to separate these entities through serology, although not ...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e3283560840

    authors: Papiris SA,Kagouridis K,Bouros D

    更新日期:2012-09-01 00:00:00

  • The small airways in chronic obstructive pulmonary disease: pathology and effects on disease progression and survival.

    abstract:PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) is caused by a mixture of small airway disease (obstructive bronchitis) and parenchymal lung tissue destruction (emphysema). The relative contributions of these two pathologic states vary from person to person. Having the ability to phenotype patients into ...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e32835ceefc

    authors: Stewart JI,Criner GJ

    更新日期:2013-03-01 00:00:00

  • Impact of cancers and cardiovascular diseases in chronic obstructive pulmonary disease.

    abstract:PURPOSE OF REVIEW:Cardiovascular disease and cancer are the two leading causes of morbidity and mortality in patients with chronic obstructive pulmonary disease. The epidemiological and mechanistic evidence linking these disorders, however, is uncertain. RECENT FINDINGS:In patients with mild chronic obstructive pulmon...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e3282f45ffb

    authors: Sin DD,Man SF

    更新日期:2008-03-01 00:00:00

  • Obstructive sleep apnea in chronic obstructive pulmonary disease patients.

    abstract:PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) represent two of the most prevalent chronic respiratory disorders and cardiovascular diseases are major co-morbidities in both. Co-existence of both disorders (overlap syndrome) occurs in 1% of adults and overlap patients h...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e32834317bb

    authors: Lee R,McNicholas WT

    更新日期:2011-03-01 00:00:00

  • Management of malignant pleural effusions: questions that need answers.

    abstract:PURPOSE OF REVIEW:Malignant pleural effusion (MPE) is common. However, regardless of the differences between patients, their underlying cancer type, and pleural fluid characteristics, management options are often limited. These have not advanced significantly over the last 80 years since pleurodesis was first described...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0b013e3283615b67

    authors: Davies HE,Lee YC

    更新日期:2013-07-01 00:00:00

  • Pulmonary physiology in interstitial lung disease: recent developments in diagnostic and prognostic implications.

    abstract::Pulmonary function changes in interstitial lung disease are characterized by loss of lung volume, increase in ratio of forced expiratory volume in 1 second to forced vital capacity, and decrease in carbon monoxide diffusion capacity. Recent developments in the assessment of respiratory mechanics in infiltrative lung d...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-199609000-00005

    authors: Baydur A

    更新日期:1996-09-01 00:00:00

  • Renal and hepatobiliary dysfunction in chronic obstructive pulmonary disease.

    abstract:PURPOSE OF REVIEW:This review examines the associations between chronic obstructive pulmonary disease (COPD) and renal and hepatobiliary diseases, with emphasis on the epidemiology and clinical outcomes, along with current information on pathophysiologic mechanisms and risk factors. RECENT FINDINGS:Glomerular filtrati...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000024

    authors: Mapel D

    更新日期:2014-03-01 00:00:00

  • Inhaled corticosteroids in chronic obstructive pulmonary disease: is there a long-term benefit?

    abstract:PURPOSE OF REVIEW:The use of inhaled corticosteroids is one of the most controversial issues in COPD pharmacotherapy. Experts disagree about the benefits and harms of ICS for patients with COPD, yet a majority of patients with COPD are being treated with inhaled corticosteroids. This is a review of the most recent lite...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-200403000-00005

    authors: Highland KB

    更新日期:2004-03-01 00:00:00

  • Scintigraphic evaluation of lung deposition with a novel inhaler device.

    abstract::A gamma-scintigraphic study was carried out in 13 healthy individuals to compare the lung deposition of budesonide from a novel multidose dry powder inhaler (MDPI; Novolizer) with that from the Pulmicort Turbuhaler, and to assess the degree of flow rate dependence of the Novolizer. Median whole lung depositions for th...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Newman SP,Hirst PH,Pitcairn GR

    更新日期:2001-04-01 00:00:00

  • Diabetes, insulin resistance, and asthma: a review of potential links.

    abstract:PURPOSE OF REVIEW:Disorders of glucose metabolism, including insulin resistance, prediabetes, and diabetes, have been identified as risk factors for worsened asthma. This review summarizes emerging evidence for their role as modifiable risk factors in asthma, including the potential benefit of diabetes medications on a...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章

    doi:10.1097/MCP.0000000000000738

    authors: Wu TD

    更新日期:2021-01-01 00:00:00

  • Cancer in interstitial pulmonary fibrosis and sarcoidosis.

    abstract::The occurrence of lung cancer in patients with diffuse interstitial pulmonary disease is well-known. The incidence, however, varies and ranges from 9.8 to 38%. The pathogenesis of lung cancer in pulmonary fibrosis is unclear, but genetic as well as environmental factors seem to be involved. ...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00063198-200309000-00010

    authors: Sharma OP,Lamb C

    更新日期:2003-09-01 00:00:00

  • Treatment options for patients with recurrent, symptomatic pleural effusions secondary to heart failure.

    abstract:PURPOSE OF REVIEW:Pleural effusions are a common finding in the nearly six million Americans diagnosed with heart failure. This review focuses on the historical, present and potential future trends in the management of such benign pleural effusions. RECENT FINDINGS:The management of symptomatic pleural effusions, in g...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000176

    authors: Freeman RK

    更新日期:2015-07-01 00:00:00

  • Lung transplantation in cystic fibrosis patients with difficult to treat lung infections.

    abstract:PURPOSE OF REVIEW:In cystic fibrosis (CF) patients with end-stage pulmonary disease, lung transplantation (LTx) remains a life-extending therapy with good outcome in most patients. Despite early concern about chronic pretransplantation infections in the context of posttransplantation immunosuppression, typical CF-assoc...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MCP.0000000000000431

    authors: Dupont L

    更新日期:2017-11-01 00:00:00

  • Bronchiolitis with airflow obstruction.

    abstract::Bronchiolar lesions are becoming increasingly recognized as an important cause of airflow obstruction. For this reason, it is helpful to have an update of the current clinical, radiographic, and immunologic perspective. Among the bronchiolar airflow disorders, diffuse panbronchiolitis is related to HLA antigen Bw54, a...

    journal_title:Current opinion in pulmonary medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Epler GR

    更新日期:1995-03-01 00:00:00