Abstract:
PURPOSE OF REVIEW:Diagnosis of idiopathic interstitial pneumonias (IIPs) requires the exclusion of, among others, concomitant connective tissue diseases (CTDs), which may present as interstitial lung disease (ILD). This review focuses on the evaluation required to separate these entities through serology, although not exclusively. RECENT FINDINGS:Several recent data suggest that patients diagnosed with IIPs can show evidence of CTDs on follow-up. This is especially true for nonspecific interstitial pneumonia but may also be seen with other forms of ILD. SUMMARY:ILDs may occur alone, IIPs, or in association with, among others, CTDs. In the latter case, they may present before, during or even several months or years after the fulfillment of undisputed criteria for CTDs. If present before, their presentation presupposes their occurrence in early undiagnosed, undefined or undifferentiated CTD, which occasionally indefinitely maintains this status of diagnostic uncertainty, especially if ILD is empirically treated by immunosuppressants. Serologic evaluation for autoantibodies assisted by serum inflammatory biomarkers, detailed search for clinical clues of CTDs and suggestive histopathologic features on lung specimens may provide a framework to build the correct diagnosis. Obtaining a diagnosis of ILD associated with CTD exceeds semantics as this subset of patients may present different natural history, pathobiology, treatment and prognosis.
journal_name
Curr Opin Pulm Medjournal_title
Current opinion in pulmonary medicineauthors
Papiris SA,Kagouridis K,Bouros Ddoi
10.1097/MCP.0b013e3283560840subject
Has Abstractpub_date
2012-09-01 00:00:00pages
433-40issue
5eissn
1070-5287issn
1531-6971journal_volume
18pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:Patients with lung cancer are particularly vulnerable to lung injury associated with immune checkpoint inhibition and often present with more frequent and more severe manifestations of lung disease compared to patients with other tumor types. The present review explores the reasons for increased susce...
journal_title:Current opinion in pulmonary medicine
pub_type: 杂志文章,评审
doi:10.1097/MCP.0000000000000689
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journal_title:Current opinion in pulmonary medicine
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doi:10.1097/00063198-200005000-00003
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journal_title:Current opinion in pulmonary medicine
pub_type: 杂志文章,评审
doi:10.1097/MCP.0b013e32832c975a
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abstract::Although asthma is considered to be an inflammatory disease of the airways, neural mechanisms remain very important. Neural control of airways is far more complex than has been previously recognized. In addition to the classic neural pathways, the nonadrenergic, noncholinergic pathway has been described in the airways...
journal_title:Current opinion in pulmonary medicine
pub_type: 杂志文章,评审
doi:10.1097/00063198-199801000-00004
更新日期:1998-01-01 00:00:00
abstract::The nontuberculous mycobacteria (NTM), especially Mycobacterium avium complex, are being recognized with increasing frequency as clinical pathogens, not only as a cause of disseminated disease in patients with AIDS but also as a cause of chronic lung disease in patients without AIDS. These infections have traditionall...
journal_title:Current opinion in pulmonary medicine
pub_type: 杂志文章,评审
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journal_title:Current opinion in pulmonary medicine
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doi:10.1097/MCP.0b013e328273bc5c
更新日期:2007-09-01 00:00:00
abstract:PURPOSE OF REVIEW:After 'curative' resection, many patients are still at risk for further lung cancer, either as a recurrence or a new metachronous primary. In theory, close follow-up should improve survival by catching relapse early - but in reality, many experts feel that surveillance for recurrence is of uncertain v...
journal_title:Current opinion in pulmonary medicine
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更新日期:2017-07-01 00:00:00
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journal_title:Current opinion in pulmonary medicine
pub_type: 杂志文章,评审
doi:10.1097/MCP.0b013e32835b10ec
更新日期:2013-01-01 00:00:00
abstract:PURPOSE OF REVIEW:To discuss the current use of oral corticosteroids (OCS) as a chronic treatment in patients with severe asthma and as a rescue treatment for patients presenting with acute exacerbations. RECENT FINDINGS:Airways disease is responsible for the bulk of OCS use in the community and considerable OCS-assoc...
journal_title:Current opinion in pulmonary medicine
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journal_title:Current opinion in pulmonary medicine
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journal_title:Current opinion in pulmonary medicine
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更新日期:2018-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Disorders of glucose metabolism, including insulin resistance, prediabetes, and diabetes, have been identified as risk factors for worsened asthma. This review summarizes emerging evidence for their role as modifiable risk factors in asthma, including the potential benefit of diabetes medications on a...
journal_title:Current opinion in pulmonary medicine
pub_type: 杂志文章
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更新日期:2021-01-01 00:00:00
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更新日期:2020-05-01 00:00:00
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journal_title:Current opinion in pulmonary medicine
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更新日期:2016-11-01 00:00:00
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更新日期:2016-03-01 00:00:00
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journal_title:Current opinion in pulmonary medicine
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更新日期:2015-11-01 00:00:00
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journal_title:Current opinion in pulmonary medicine
pub_type: 杂志文章,评审
doi:10.1097/MCP.0b013e3282f10a16
更新日期:2007-11-01 00:00:00
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journal_title:Current opinion in pulmonary medicine
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更新日期:2012-11-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this article is to provide understanding of renal sarcoidosis, the different types of renal sarcoidosis, disease burden of renal involvement, and treatment options. RECENT FINDINGS:The frequency of renal involvement seems to be underestimated, but renal sarcoidosis represents a relevan...
journal_title:Current opinion in pulmonary medicine
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journal_title:Current opinion in pulmonary medicine
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journal_title:Current opinion in pulmonary medicine
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doi:10.1097/00063198-200405000-00008
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journal_title:Current opinion in pulmonary medicine
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更新日期:2012-01-01 00:00:00
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journal_title:Current opinion in pulmonary medicine
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更新日期:2018-07-01 00:00:00
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journal_title:Current opinion in pulmonary medicine
pub_type: 杂志文章,评审
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更新日期:2008-01-01 00:00:00
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journal_title:Current opinion in pulmonary medicine
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更新日期:1997-01-01 00:00:00
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journal_title:Current opinion in pulmonary medicine
pub_type: 杂志文章,评审
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更新日期:1996-05-01 00:00:00
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journal_title:Current opinion in pulmonary medicine
pub_type: 杂志文章,评审
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