Pathogenesis and prevention strategies of severe asthma exacerbations in children.

abstract：PURPOSE OF REVIEW:The Burkholderia cepacia complex is comprised of a group of related bacterial species that are capable of causing life-threatening respiratory tract infection in persons with cystic fibrosis. This article reviews advances in our understanding of Burkholderia cepacia complex infection in cystic fibrosi...

journal_title：Current opinion in pulmonary medicine

authors： Lipuma JJ

更新日期：2005-11-01 00:00:00

abstract：:Although asthma is considered to be an inflammatory disease of the airways, neural mechanisms remain very important. Neural control of airways is far more complex than has been previously recognized. In addition to the classic neural pathways, the nonadrenergic, noncholinergic pathway has been described in the airways...

journal_title：Current opinion in pulmonary medicine

authors： Choi DC,Kwon OJ

更新日期：1998-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The role of thoracic surgery in pulmonary tuberculosis, in either a diagnostic or a therapeutic role, is well established. This review aims to underline the current indications for lung resection, surgical strategy and outcomes associated with surgery. RECENT FINDINGS:There has been a renewed interes...

journal_title：Current opinion in pulmonary medicine

authors： Naidoo R

更新日期：2008-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines the associations between chronic obstructive pulmonary disease (COPD) and renal and hepatobiliary diseases, with emphasis on the epidemiology and clinical outcomes, along with current information on pathophysiologic mechanisms and risk factors. RECENT FINDINGS:Glomerular filtrati...

journal_title：Current opinion in pulmonary medicine

authors： Mapel D

更新日期：2014-03-01 00:00:00

abstract：:Staging of sarcoidosis needs a synthesis of clinical features, histology, radiology, biochemical changes, and immunologic aberrations to distinguish this disease from nonspecific sarcoid-tissue reactions. The main aim of this report is to offer readers an overview on immunologic markers that have been evaluated in the...

journal_title：Current opinion in pulmonary medicine

authors： Semenzato G,Bortoli M,Agostini C

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Matrix metalloproteinases (MMPs) are a family of over 20 zinc-dependent proteases with different biological and pathological activities, and many have been implicated in several diseases. Although nonselective MMP inhibitors are known to induce serious side-effects, targeting individual MMPs may offer...

journal_title：Current opinion in pulmonary medicine

authors： Abd-Elaziz K,Jesenak M,Vasakova M,Diamant Z

更新日期：2021-01-01 00:00:00

abstract：PURPOSE OF REVIEW:although long-acting beta-agonists (LABAs) have been used for two decades, with many studies showing benefit versus increasing inhaled corticosteroid (ICS), controversy regarding safety has resulted in the United States Food and Drug Administration (FDA) recently mandating label changes restricting LA...

journal_title：Current opinion in pulmonary medicine

authors： Sears MR

更新日期：2011-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Control of tuberculosis necessitates prompt diagnosis and access to effective treatment. We discuss the impact of a new nucleic acid amplification test to assist diagnosis and detect rifampicin resistance. Following encouraging clinical performance studies, an automated PCR-based test, the Xpert MTB/R...

journal_title：Current opinion in pulmonary medicine

authors： McNerney R,Zumla A

更新日期：2015-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This article aims to review the most recent proteomic findings in tissue and biological fluids and application of new technologies for the study of interstitial lung diseases. RECENT FINDINGS:New insights into lung cell biology as well as novel pathogenetic pathways of different interstitial lung dis...

journal_title：Current opinion in pulmonary medicine

authors： Rottoli P,Bargagli E,Landi C,Magi B

更新日期：2009-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Community-acquired pneumonia (CAP) is the most common infectious disease cause of death. We summarize recent findings regarding the epidemiology of CAP in adults, efficacy of vaccines against Streptococcus pneumoniae, diagnostics, and discuss the current controversy between CAP and healthcare-associat...

journal_title：Current opinion in pulmonary medicine

authors： José RJ,Periselneris JN,Brown JS

更新日期：2015-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Adherence to asthma therapies is poor leading to unnecessary morbidity and increased use of emergency and hospital resources. Strategies to improve adherence have not been successful. RECENT FINDINGS:Asthma adherence disease management is a clinical method to improve adherence for asthma patients. Th...

journal_title：Current opinion in pulmonary medicine

authors： Weinstein AG

更新日期：2015-01-01 00:00:00

abstract：:Patients with acute deep vein thrombosis (DVT) were treated with a body-weight independent dosage of 2 x 8000 aXa IU low-molecular-weight heparin (LMWH) Certoparin. After the subcutaneous administration of 8000 IU Certoparin, pharmacodynamic parameters did not differ between patients and healthy volunteers, and the AU...

journal_title：Current opinion in pulmonary medicine

authors： Harenberg J

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The catastrophic collapse of the World Trade Center (WTC) towers on September 11, 2001 created a large-scale disaster site in a densely populated urban environment. Over the ensuing months, tens of thousands of rescue, recovery and cleanup workers, volunteers, and residents of the adjacent community w...

journal_title：Current opinion in pulmonary medicine

authors： Banauch GI,Dhala A,Prezant DJ

更新日期：2005-03-01 00:00:00

abstract：:Disorders of sleep in children are distinctly different from sleep disorders in adults. Since children are forced to constantly learn and adapt, the effects of disordered sleep may be more profound. This paper reviews the disorders of sleep that are most significant in each of the stages of development from infancy to...

journal_title：Current opinion in pulmonary medicine

authors： Anstead M

更新日期：2000-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Ever since sarcoidosis was first described, its relationship with tuberculosis has been debated. Whereas some consider sarcoidosis and tuberculosis as two extremes of the same disease process, other researchers have negated the role of mycobacteria in causation of sarcoidosis. Whether or not linked ca...

journal_title：Current opinion in pulmonary medicine

authors： Gupta D,Agarwal R,Aggarwal AN,Jindal SK

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Pulmonary cystic echinococcosis, a zoonosis caused by the larvae of the dog tapeworm Echinococcus granulosus, is considered as a major public health problem in countries where dogs are used to care for large herds. Despite its frequency and widespread endemicity, the literature on pulmonary cystic ech...

journal_title：Current opinion in pulmonary medicine

authors： Santivanez S,Garcia HH

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the principles of staging cancer as applied to nonsmall cell lung cancer. RECENT FINDINGS:The current staging system is under review for update. It is timely to review the principles of staging cancer to see how the nonsmall cell lung cancer staging system can be improved. Staging systems s...

journal_title：Current opinion in pulmonary medicine

authors： Filner JJ,Ost D

更新日期：2008-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) imposes a large burden on the global population and even more so for the elderly who face significant obstacles in the diagnosis, management, and psychosocial effects of the disease. This review describes the current challenges and key points in the managem...

journal_title：Current opinion in pulmonary medicine

authors： Allen B,Aboussouan LS

更新日期：2021-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review was to evaluate the consequence of obstructive sleep apnea (OSA) in pulmonary hypertension by reviewing the current literature and understanding potential pathophysiological mechanisms. RECENT FINDINGS:Small studies have suggested a high prevalence of comorbid OSA in those ...

journal_title：Current opinion in pulmonary medicine

authors： Minic M,Ryan CM

更新日期：2015-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Spontaneous hemopneumothorax can be life threatening, and is a cause of patients presenting with unexplained signs of significant hypovolemia. The debate relating to patient selection and timing of surgery in patients with spontaneous hemopneumothorax remains unresolved. RECENT FINDINGS:Our experienc...

journal_title：Current opinion in pulmonary medicine

authors： Ng CSh,Yim AP

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the fact that primary pulmonary lymphoma (PPL) is a rare lung tumour, significant advances addressing clinical features, histological diagnosis, prognostic criteria and therapeutic management of this disease have been made within the past decade. RECENT FINDINGS:Monoclonality and phenotyping ...

journal_title：Current opinion in pulmonary medicine

authors： Cardenas-Garcia J,Talwar A,Shah R,Fein A

更新日期：2015-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This article aims to review the geological background of environmental asbestos exposure and the distribution of asbestos-related disease (ARD) in association with naturally occurring asbestos (NOA), and discusses the potential health risks associated with exposure to non-occupational asbestos. RECEN...

journal_title：Current opinion in pulmonary medicine

authors： Bayram M,Bakan ND

更新日期：2014-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The objective is to discuss recent progress in our understanding of the role of the indoor environment in asthma, focusing on the special role of cat allergens. RECENT FINDINGS:Sensitization to Fel d 1 is the dominant event in inhalant responses to cat; however, there are also IgE responses to the li...

journal_title：Current opinion in pulmonary medicine

authors： Kelly LA,Erwin EA,Platts-Mills TA

更新日期：2012-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This manuscript reviews the recent literature related to new developments in the understanding of existing and novel virulence factors of the pneumococcus that are of potential importance in the development of novel preventive and therapeutic strategies. RECENT FINDINGS:The pneumococcal capsule and p...

journal_title：Current opinion in pulmonary medicine

authors： Feldman C,Anderson R

更新日期：2020-05-01 00:00:00

abstract：PURPOSE OF REVIEW:It is increasingly clear that asthma is not a single disease, but a disorder with vast heterogeneity in pathogenesis, severity, and treatment response. In this review, we discuss the present understanding of different asthma phenotypes and endotypes, and the prospects of personalized medicine for asth...

journal_title：Current opinion in pulmonary medicine

authors： Lin TY,Poon AH,Hamid Q

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF REVIEW:After the disappointing results of lung cancer screening trials conducted in the 1960s to the 1980s, a renewed interest in lung cancer screening emerged in the 1990s with the development of new technologies such as low-dose spiral CT. The literature regarding screening with biomarkers and CT continues...

journal_title：Current opinion in pulmonary medicine

authors： Manser R

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Heparin-induced thrombocytopenia is a severe side effect of treatment with unfractionated heparin. The relation of low-molecular-weight heparin to heparin-induced thrombocytopenia is less well understood. This review will summarize what is known about the similarities and differences between thrombocy...

journal_title：Current opinion in pulmonary medicine

authors： Walenga JM,Prechel M,Jeske WP,Bakhos M

更新日期：2005-09-01 00:00:00

abstract：:The goal of management of patients with respiratory failure is to restore them to a state of quiet breathing, without complication. This goal is often achieved by pharmacotherapy alone. Inhaled albuterol sulfate, oxygen, and systemic corticosteroids are mainstays of acute care drug management, whereas other data suppo...

journal_title：Current opinion in pulmonary medicine

authors： Gluckman TJ,Corbridge T

更新日期：2000-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Cystic fibrosis (CF) is a complex genetic disease affecting many organs, although 85% of the mortality is a result of lung disease. The natural history of the lung disease consists of early and persistent infection, an exaggerated inflammatory response, structural airway changes (i.e. bronchiectasis),...

journal_title：Current opinion in pulmonary medicine

authors： Flume PA

更新日期：2011-07-01 00:00:00

abstract：:The pleural space in healthy humans was thought to contain a few milliliters of fluid, based on extrapolation from animal studies. However, because of the obvious technical difficulties in atraumatically retrieving such a small volume of fluid, the exact volume and cellular content of human pleural fluid has not been ...

journal_title：Current opinion in pulmonary medicine

authors： Noppen M

更新日期：2001-07-01 00:00:00