Applied clinical immunology in sarcoidosis.

Abstract:

:Staging of sarcoidosis needs a synthesis of clinical features, histology, radiology, biochemical changes, and immunologic aberrations to distinguish this disease from nonspecific sarcoid-tissue reactions. The main aim of this report is to offer readers an overview on immunologic markers that have been evaluated in the last years with the ultimate goal of relating their determination to the management of the disease. The first part is devoted to immunologic markers that have been proposed to define the activity of the T-cell component of the sarcoid inflammatory process. In the second part of the paper, we will provide a descriptive definition of immunologic markers of activity of sarcoid macrophages relating them to the clinical course of sarcoidosis.

journal_name

Curr Opin Pulm Med

authors

Semenzato G,Bortoli M,Agostini C

doi

10.1097/00063198-200209000-00017

keywords:

subject

Has Abstract

pub_date

2002-09-01 00:00:00

pages

441-4

issue

5

eissn

1070-5287

issn

1531-6971

journal_volume

8

pub_type

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