Influenza update: vaccine development and clinical trials.

abstract：:Prognosis for patients with cystic fibrosis has improved dramatically over the past three decades. In the United States, median survival age is now 28.9 years. Although genotype predicts exocrine pancreatic function, it does not correlate with pulmonary status or overall clinical outcome. However, there are a number o...

journal_title：Current opinion in pulmonary medicine

authors： Rosenstein BJ,Zeitlin PL

更新日期：1995-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma outcomes constitute the cornerstone of asthma clinical research. Despite their known importance, it has been difficult for researchers to standardize these outcomes in large part because of the heterogeneity of the disease. This review seeks to provide an overview of recent recommendations for ...

journal_title：Current opinion in pulmonary medicine

authors： Parulekar AD,Alobaidy A,Hanania NA

更新日期：2013-01-01 00:00:00

abstract：:The bacillary population described in tuberculous pleuritis is small, and its most likely pathogenetic mechanism is essentially immunologic. This explains why, until now, the diagnostic identification of tuberculous pleuritis (TP) has been based on the presence of granulomas in pleural biopsy. Correcting this diagnost...

journal_title：Current opinion in pulmonary medicine

authors： Pérez-Rodriguez E,Jiménez Castro D

更新日期：2000-07-01 00:00:00

abstract：:This review summarizes the recent literature published on the microbiology, diagnosis, and medical and surgical management of acute and chronic frontal sinus disease. Two retrospective studies investigated the microbiology of frontal sinusitis in patients that underwent sinus surgery. Streptococcus pneumoniae, Haemoph...

journal_title：Current opinion in pulmonary medicine

authors： Brook I

更新日期：2003-05-01 00:00:00

abstract：:Interstitial lung diseases are characterized by disruption of the distal pulmonary parenchyma. The clinical history manifestations, cough and dyspnea, and physical exam manifestations, inspiratory crackles, are nonspecific. Pulmonary function testing aids in the evaluation and management of patients with interstitial ...

journal_title：Current opinion in pulmonary medicine

authors： Flaherty KR,Martinez FJ

更新日期：2000-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The use of noninvasive ventilatory support in patients with cystic fibrosis (CF) has increased exponentially over the past 2 decades. This review examines the current knowledge and considers potential future directions for use of noninvasive ventilation in CF patients. RECENT FINDINGS:Noninvasive ven...

journal_title：Current opinion in pulmonary medicine

authors： Bright-Thomas RJ,Johnson SC

更新日期：2014-11-01 00:00:00

abstract：:The majority of men with cystic fibrosis (CF) have associated congenital bilateral absence of the vas deferens (CBVAD). This congenital defect results in the absence of the anatomic ducts through which spermatozoa pass from the testes to the urethra. No spermatozoa are found in the semen, a condition referred to as ob...

journal_title：Current opinion in pulmonary medicine

authors： Sokol RZ

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the fact that primary pulmonary lymphoma (PPL) is a rare lung tumour, significant advances addressing clinical features, histological diagnosis, prognostic criteria and therapeutic management of this disease have been made within the past decade. RECENT FINDINGS:Monoclonality and phenotyping ...

journal_title：Current opinion in pulmonary medicine

authors： Cardenas-Garcia J,Talwar A,Shah R,Fein A

更新日期：2015-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The use of inhaled corticosteroids is one of the most controversial issues in COPD pharmacotherapy. Experts disagree about the benefits and harms of ICS for patients with COPD, yet a majority of patients with COPD are being treated with inhaled corticosteroids. This is a review of the most recent lite...

journal_title：Current opinion in pulmonary medicine

authors： Highland KB

更新日期：2004-03-01 00:00:00

abstract：:Staging of sarcoidosis needs a synthesis of clinical features, histology, radiology, biochemical changes, and immunologic aberrations to distinguish this disease from nonspecific sarcoid-tissue reactions. The main aim of this report is to offer readers an overview on immunologic markers that have been evaluated in the...

journal_title：Current opinion in pulmonary medicine

authors： Semenzato G,Bortoli M,Agostini C

更新日期：2002-09-01 00:00:00

abstract：:Disorders of sleep in children are distinctly different from sleep disorders in adults. Since children are forced to constantly learn and adapt, the effects of disordered sleep may be more profound. This paper reviews the disorders of sleep that are most significant in each of the stages of development from infancy to...

journal_title：Current opinion in pulmonary medicine

authors： Anstead M

更新日期：2000-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine recent reports of serosal involvement in sarcoidosis. RECENT FINDINGS:Peritoneal sarcoidosis continues to be a rare manifestation of the disease. Patients with peritoneal disease tend to be women between the ages of 20 and 40 years, and most commonly present with ascites and abdominal pain...

journal_title：Current opinion in pulmonary medicine

authors： Iyer S,Afshar K,Sharma OP

更新日期：2008-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Minimally invasive diagnostic strategies for pulmonary embolism are in constant evolution, integrating new diagnostic tools along with the better use of clinical information. RECENT FINDINGS:In the past year, several reports have provided more data on the value of clinical signs and symptoms for diag...

journal_title：Current opinion in pulmonary medicine

authors： Le Gal G,Perrier A

更新日期：2006-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiovascular disease and cancer are the two leading causes of morbidity and mortality in patients with chronic obstructive pulmonary disease. The epidemiological and mechanistic evidence linking these disorders, however, is uncertain. RECENT FINDINGS:In patients with mild chronic obstructive pulmon...

journal_title：Current opinion in pulmonary medicine

authors： Sin DD,Man SF

更新日期：2008-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Nowadays tuberculosis is becoming a worldwide problem, and according to the World Health Organization, which declared tuberculosis a global health emergency in 1993, each year 8 million people worldwide develop the active disease and almost 3 million die. RECENT FINDINGS:Due to this problem there is ...

journal_title：Current opinion in pulmonary medicine

authors： de Souza MV

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) represent two of the most prevalent chronic respiratory disorders and cardiovascular diseases are major co-morbidities in both. Co-existence of both disorders (overlap syndrome) occurs in 1% of adults and overlap patients h...

journal_title：Current opinion in pulmonary medicine

authors： Lee R,McNicholas WT

更新日期：2011-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent work demonstrates that patients with refractory asthma are likely to be sensitized to environmental fungi and that specific antifungal treatments may be of benefit to this group. RECENT FINDINGS:The relationships among fungal sensitization, exposure and asthma severity are imperfectly understo...

journal_title：Current opinion in pulmonary medicine

authors： Gore RB

更新日期：2010-01-01 00:00:00

abstract：:The pleural space in healthy humans was thought to contain a few milliliters of fluid, based on extrapolation from animal studies. However, because of the obvious technical difficulties in atraumatically retrieving such a small volume of fluid, the exact volume and cellular content of human pleural fluid has not been ...

journal_title：Current opinion in pulmonary medicine

authors： Noppen M

更新日期：2001-07-01 00:00:00

abstract：:The most common syndromes associated with obstructive lung disease are asthma and chronic obstructive pulmonary disease (COPD). Evidence for a viral etiology of asthmatic exacerbations is well known, but evidence for a role for viruses in COPD exacerbation is just emerging. Viruses may cause chronic infection in both ...

journal_title：Current opinion in pulmonary medicine

authors： Seemungal TA,Wedzicha JA

更新日期：2003-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Diagnosis of sleep apnoea was performed in sleep laboratories with polysomnography. This requires a room with supervision and presence of technologists and trained sleep experts. Today, clinical guidelines in most countries recommend home sleep apnoea testing with simple systems using six signals only...

journal_title：Current opinion in pulmonary medicine

authors： Penzel T,Fietze I,Glos M

更新日期：2020-11-01 00:00:00

abstract：PURPOSE OF REVIEW:After 'curative' resection, many patients are still at risk for further lung cancer, either as a recurrence or a new metachronous primary. In theory, close follow-up should improve survival by catching relapse early - but in reality, many experts feel that surveillance for recurrence is of uncertain v...

journal_title：Current opinion in pulmonary medicine

authors： Chang CF,Gould M

更新日期：2017-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights recent developments in liver disease associated with cystic fibrosis. RECENT FINDINGS:The broad spectrum of hepatobiliary problems in cystic fibrosis includes specific alterations ascribable to the underlying defect as well as lesions of iatrogenic origin or that reflect the ef...

journal_title：Current opinion in pulmonary medicine

authors： Colombo C

更新日期：2007-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Medical thoracoscopy provides the physician a window into the pleural space. The procedure allows biopsy of the parietal pleura under direct visualization with good accuracy. In addition, it achieves therapeutic goals of fluid drainage, guided chest tube placement, and pleurodesis. RECENT FINDINGS:Co...

journal_title：Current opinion in pulmonary medicine

authors： Lee P,Mathur PN

更新日期：2016-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the current understanding and clinical applicability of severity scoring systems in pneumonia management. RECENT FINDINGS:Severity scores in community-acquired pneumonia are strong markers of mortality, but are not necessarily clinical decision-aid tools. The use of severity scores to sup...

journal_title：Current opinion in pulmonary medicine

authors： Ranzani OT,Taniguchi LU,Torres A

更新日期：2018-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Coal mine workers are at risk for a range of chronic respiratory diseases including coal workers' pneumoconiosis, diffuse dust-related fibrosis, and chronic obstructive pulmonary disease. The purpose of this review is to describe coal mining processes and associated exposures to inform the diagnostic ...

journal_title：Current opinion in pulmonary medicine

authors： Go LH,Krefft SD,Cohen RA,Rose CS

更新日期：2016-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Subsequent to the ATS/ERS consensus classification of idiopathic interstitial pneumonia, non-specific interstitial pneumonia pattern was the dominant pattern in many collagen vascular diseases, which may explain the better prognosis of interstitial pneumonia associated with collagen disease than idiop...

journal_title：Current opinion in pulmonary medicine

authors： Kim DS

更新日期：2006-09-01 00:00:00

abstract：:It is usually assumed that upper airway pressure receptors mediate the reflexes involved in sleep apneas, but many other receptors may be involved, including those responding to chemical stimuli. The reflexes to upper airway negative pressure have been further studied, and the timing of their inputs shown to be import...

journal_title：Current opinion in pulmonary medicine

authors： Widdicombe J

更新日期：1998-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Obstructive sleep apnea (OSA) is heterogeneous in terms of contributing pathophysiological mechanisms, clinical presentation, and consequences. Different study models from animal models of intermittent hypoxia over case-control, cohort, and population-based observational studies to uncontrolled interv...

journal_title：Current opinion in pulmonary medicine

authors： Schwarz EI

更新日期：2019-11-01 00:00:00

abstract：:Uvulopalatopharyngoplasty has limited efficacy in treating obstructive sleep apnea, with excellent results achieved in fewer than half of patients who undergo this procedure. Attempting to select patients who have only retropalatal collapse of the pharynx increases the likelihood of a successful outcome. Although this...

journal_title：Current opinion in pulmonary medicine

authors： Sher AE

更新日期：1995-11-01 00:00:00

abstract：:Some time ago, the Th2 cytokine, interleukin (IL)-13, was identified as a critical regulator of the allergic response. Initial studies in animal models of disease provided compelling evidence that IL-13, independent from other Th2 cytokines, was necessary and sufficient to induce all features of allergic asthma. This ...

journal_title：Current opinion in pulmonary medicine

authors： Wills-Karp M,Chiaramonte M

更新日期：2003-01-01 00:00:00