Management of small cell cancer of the lung.

abstract：:Lung cancer is the leading cause of cancer-related death worldwide. For patients diagnosed with early-stage lung cancer, complete surgical resection remains the best hope for cure. Limited resections are avoided when possible because of higher recurrence rates and potentially worse long-term survival. Traditionally, a...

journal_title：Current opinion in pulmonary medicine

authors： Moffatt SD,Mitchell JD,Whyte RI

更新日期：2002-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) imposes a large burden on the global population and even more so for the elderly who face significant obstacles in the diagnosis, management, and psychosocial effects of the disease. This review describes the current challenges and key points in the managem...

journal_title：Current opinion in pulmonary medicine

authors： Allen B,Aboussouan LS

更新日期：2021-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypersensitivity pneumonitis (HP), also known as extrinsic allergic alveolitis, is a granulomatous, inflammatory disease of the lungs caused by the inhalation of antigenic organic particles or fumes. The disease may present as an acute, subacute, or chronic illness. Episodes of acute and subacute HP u...

journal_title：Current opinion in pulmonary medicine

authors： Mohr LC

更新日期：2004-09-01 00:00:00

abstract：:It is usually assumed that upper airway pressure receptors mediate the reflexes involved in sleep apneas, but many other receptors may be involved, including those responding to chemical stimuli. The reflexes to upper airway negative pressure have been further studied, and the timing of their inputs shown to be import...

journal_title：Current opinion in pulmonary medicine

authors： Widdicombe J

更新日期：1998-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update on the implementation of precision medicine, based on treatable traits and mechanisms, in the daily clinical management of chronic airways diseases. RECENT FINDINGS:Recent insights into the complex and heterogeneous nature of chronic airway diseases including chronic obstructive ...

journal_title：Current opinion in pulmonary medicine

authors： Ulrik CS,Vijverberg S,Hanania NA,Diamant Z

更新日期：2020-01-01 00:00:00

abstract：:Pulmonary embolism occurs in more than 175,000 patients each year in the United States. The objectives of treatment are to prevent death from the existing embolus, to prevent death and morbidity from recurrent pulmonary embolism, and to prevent morbidity from recurrent deep-vein thrombosis. For patients with adequate ...

journal_title：Current opinion in pulmonary medicine

authors： Raskob GE

更新日期：1999-07-01 00:00:00

abstract：PURPOSE OF REVIEW:There has been much recent interest in the use of macrolide antibiotics as chronic suppressive therapy in patients with cystic fibrosis. Three recent randomized, placebo-controlled trials have been conducted. RECENT FINDINGS:All three trials used similar regimens of azithromycin, and lung function im...

journal_title：Current opinion in pulmonary medicine

authors： Saiman L

更新日期：2004-11-01 00:00:00

abstract：:The occurrence of lung cancer in patients with diffuse interstitial pulmonary disease is well-known. The incidence, however, varies and ranges from 9.8 to 38%. The pathogenesis of lung cancer in pulmonary fibrosis is unclear, but genetic as well as environmental factors seem to be involved. ...

journal_title：Current opinion in pulmonary medicine

authors： Sharma OP,Lamb C

更新日期：2003-09-01 00:00:00

abstract：:Chest tubes and their accompanying pleural drainage units continue to present challenging questions regarding their optimal use. Appropriate chest tube size selection to accommodate the clinical situation is key, especially in the setting of large pleural air leaks lest a tension pneumothorax ensue. Connection of an a...

journal_title：Current opinion in pulmonary medicine

authors： Baumann MH

更新日期：2003-07-01 00:00:00

abstract：PURPOSE OF REVIEW:It has been an ongoing challenge to translate knowledge pertaining to the molecular basis of cystic fibrosis (CF) into a clear understanding of the development of CF lung disease. Various hypotheses have attempted to explain the apparent breach of innate defenses in CF, although a definitive explanati...

journal_title：Current opinion in pulmonary medicine

authors： Donaldson SH,Boucher RC

更新日期：2003-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine recent reports of serosal involvement in sarcoidosis. RECENT FINDINGS:Peritoneal sarcoidosis continues to be a rare manifestation of the disease. Patients with peritoneal disease tend to be women between the ages of 20 and 40 years, and most commonly present with ascites and abdominal pain...

journal_title：Current opinion in pulmonary medicine

authors： Iyer S,Afshar K,Sharma OP

更新日期：2008-09-01 00:00:00

abstract：:Chronic obstructive pulmonary disease is the fourth leading cause of death in the United States, affecting approximately 10% of all adults. Several articles published during the past year contributed significantly to our understanding of the complicated management of this disease. New information concerning bronchodil...

journal_title：Current opinion in pulmonary medicine

authors： Navin DM,Gross NJ

更新日期：1996-03-01 00:00:00

abstract：PURPOSE OF REVIEW:although long-acting beta-agonists (LABAs) have been used for two decades, with many studies showing benefit versus increasing inhaled corticosteroid (ICS), controversy regarding safety has resulted in the United States Food and Drug Administration (FDA) recently mandating label changes restricting LA...

journal_title：Current opinion in pulmonary medicine

authors： Sears MR

更新日期：2011-01-01 00:00:00

abstract：:Although it had been appreciated that high levels of antituberculous drug resistance existed in some regions of the world, the full extent of the problem was not known. A combined initiative by the World Health Organization and the International Union Against Tuberculosis and Lung Disease was launched in 1994 to addre...

journal_title：Current opinion in pulmonary medicine

authors： Willcox PA

更新日期：2001-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The Sleep Heart Health Study began in 1994 as a prospective cohort study of cardiovascular disease. The results of longitudinal analysis are not yet available, but numerous analyses of cross-sectional data have been published. This review provides an overview of study results so far. RECENT FINDINGS:...

journal_title：Current opinion in pulmonary medicine

authors： Gottlieb DJ

更新日期：2008-11-01 00:00:00

abstract：:Some time ago, the Th2 cytokine, interleukin (IL)-13, was identified as a critical regulator of the allergic response. Initial studies in animal models of disease provided compelling evidence that IL-13, independent from other Th2 cytokines, was necessary and sufficient to induce all features of allergic asthma. This ...

journal_title：Current opinion in pulmonary medicine

authors： Wills-Karp M,Chiaramonte M

更新日期：2003-01-01 00:00:00

abstract：:The 24-hour properties of sleepiness affect behavior by reducing performance and increasing the likelihood of accidents. This is important to pulmonary physicians who diagnose and treat sleep apnea, because diagnoses of sleep apnea and narcolepsy are associated with as much as a sevenfold increase in the risk of havin...

journal_title：Current opinion in pulmonary medicine

authors： Mitler MM

更新日期：1996-11-01 00:00:00

abstract：:An important advance in our understanding of the pathophysiology of asthma has been the discovery that airway inflammation is not confined to severe asthma but also characterizes mild and moderate asthma. Inflammation in asthma may be the result of a peculiar type of lymphocytic inflammation whereby Th2 lymphocytes se...

journal_title：Current opinion in pulmonary medicine

authors： Fahy JV,Corry DB,Boushey HA

更新日期：2000-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Sarcoidosis is a granulomatous systemic disease of unknown cause where the lung is the most frequently affected organ. Therapeutic management of the disease is challenging as clinical presentation and prognosis are very heterogeneous. In the present review, we will summarize the main advances in sarco...

journal_title：Current opinion in pulmonary medicine

authors： Sellarés J,Francesqui J,Llabres M,Hernandez-Gonzalez F,Baughman RP

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the recent findings of the last 2 years on the epidemiology and phenotypes of occupational asthma, as well as new developments in its diagnosis and management. RECENT FINDINGS:Data from nine longitudinal studies showed a population attributable fraction for the occupational contribution t...

journal_title：Current opinion in pulmonary medicine

authors： Quirce S,Domínguez-Ortega J,Luna JA

更新日期：2021-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Ventilator-associated pneumonia (VAP) remains a frequent and severe complication in endotracheally intubated patients. Strict adherence to preventive measures reduces the risk of VAP. The objective of this paper is to review what has come forward in recent years in the nonpharmacological prevention of...

journal_title：Current opinion in pulmonary medicine

authors： Blot S,Rello J,Vogelaers D

更新日期：2011-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Glucocorticosteroids (GCSs) remain the cornerstone of therapy for treating the inflammatory component of asthma. Clinical response to GCS is heterogeneous, varying both within asthma 'endotypes', as well as the same individual. Different factors and micro-environment can alter the canonical GCS-induce...

journal_title：Current opinion in pulmonary medicine

authors： Mukherjee M,Svenningsen S,Nair P

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Effective asthma education requires more than merely providing information on asthma. Behavior change and learning principles must be incorporated into educational programs. However, there remains much debate and research about the most effective strategies to educate people to deal effectively with t...

journal_title：Current opinion in pulmonary medicine

authors： McGhan SL,Cicutto LC,Befus AD

更新日期：2005-01-01 00:00:00

abstract：PURPOSE OF REVIEW:In previous years, there was limited research related to the role of sleep in interstitial lung diseases (ILDs). Physicians treating ILD patients tended to focus mainly on the daily disabling symptoms overlooking the possible significant role of coexisting sleep disorders, such as obstructive sleep ap...

journal_title：Current opinion in pulmonary medicine

authors： Schiza SE,Bouloukaki I,Bolaki M,Antoniou KM

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Regions of the neocortex most strongly activated during waking exhibit increased sleep intensity during subsequent sleep. The novel concept that aspects of sleep homeostasis are determined locally in the cortex contrasts with the established views that global changes in neocortical activity during sle...

journal_title：Current opinion in pulmonary medicine

authors： Szymusiak R

更新日期：2010-11-01 00:00:00

abstract：:Intrathoracic neoplasms other than bronchogenic carcinoma comprise a disparate group of tumors that have in common an anatomic location within the thorax. For the purposes of this review, they are divided into three categories: pulmonary metastases from locations other than the thorax, mediastinal neoplasms, and unusu...

journal_title：Current opinion in pulmonary medicine

authors： Yoneda KY,Tharratt RS

更新日期：1997-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Obesity has significant impact on asthma incidence and manifestations. The purpose of the review is to discuss recent observations regarding the association between obesity and asthma focusing on underlying mechanisms, clinical presentation, response to therapy and effect of weight reduction. RECENT ...

journal_title：Current opinion in pulmonary medicine

authors： Sivapalan P,Diamant Z,Ulrik CS

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Need for intensive care in the patient with pulmonary arterial hypertension is associated with high mortality. This review will provide an overview of causes of ICU admission for patients with pulmonary hypertension and provide guidance on management. RECENT FINDINGS:There is a paucity of evidence-ba...

journal_title：Current opinion in pulmonary medicine

authors： Aryal S,King CS

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Telomere attrition has been proposed as one of the aging hallmarks in pulmonary fibrosis. Telomere shortening and telomerase gene mutations have been widely evaluated in recent years. Reduced telomere length may be identified in a quarter of patients with sporadic idiopathic pulmonary fibrosis (IPF) a...

journal_title：Current opinion in pulmonary medicine

authors： Molina-Molina M,Borie R

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This manuscript reviews the recent literature related to new developments in the understanding of existing and novel virulence factors of the pneumococcus that are of potential importance in the development of novel preventive and therapeutic strategies. RECENT FINDINGS:The pneumococcal capsule and p...

journal_title：Current opinion in pulmonary medicine

authors： Feldman C,Anderson R

更新日期：2020-05-01 00:00:00