Obesity and asthma: current knowledge and future needs.

abstract：:Acute bronchitis in previously fit individuals is a common condition that is usually mild and self limiting. Chronic bronchitis remains a common cause of morbidity and mortality, and the cost to the nation due to lost working days and to health services is enormous. Cigarette smoking is the major etiologic factor, alt...

journal_title：Current opinion in pulmonary medicine

authors： Wilson R,Rayner CF

更新日期：1995-05-01 00:00:00

abstract：:The most common syndromes associated with obstructive lung disease are asthma and chronic obstructive pulmonary disease (COPD). Evidence for a viral etiology of asthmatic exacerbations is well known, but evidence for a role for viruses in COPD exacerbation is just emerging. Viruses may cause chronic infection in both ...

journal_title：Current opinion in pulmonary medicine

authors： Seemungal TA,Wedzicha JA

更新日期：2003-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews current data on pathophysiologic mechanisms by which sleep-disordered breathing during pregnancy may cause harm, and explores biological pathways for associated adverse maternal and fetal outcomes, especially pregnancy-induced hypertension and gestational diabetes. RECENT FINDING...

journal_title：Current opinion in pulmonary medicine

authors： Izci-Balserak B,Pien GW

更新日期：2010-11-01 00:00:00

abstract：PURPOSE OF REVIEW:A small percentage of asthma exacerbations are linked with infection by an atypical bacterium, such as Chlamydia pneumoniae or Mycoplasma pneumoniae. These bacteria also have been proposed to cause occult chronic lower airway inflammation and to initiate nonatopic asthma in adults. Consequently, the l...

journal_title：Current opinion in pulmonary medicine

authors： Cazzola M,Matera MG,Blasi F

更新日期：2004-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the fact that primary pulmonary lymphoma (PPL) is a rare lung tumour, significant advances addressing clinical features, histological diagnosis, prognostic criteria and therapeutic management of this disease have been made within the past decade. RECENT FINDINGS:Monoclonality and phenotyping ...

journal_title：Current opinion in pulmonary medicine

authors： Cardenas-Garcia J,Talwar A,Shah R,Fein A

更新日期：2015-07-01 00:00:00

abstract：:Prognosis for patients with cystic fibrosis has improved dramatically over the past three decades. In the United States, median survival age is now 28.9 years. Although genotype predicts exocrine pancreatic function, it does not correlate with pulmonary status or overall clinical outcome. However, there are a number o...

journal_title：Current opinion in pulmonary medicine

authors： Rosenstein BJ,Zeitlin PL

更新日期：1995-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Malignant pleural effusion is a common cause of breathlessness and signifies advanced disease. Common options for definitive pleural intervention include insertion of an indwelling pleural catheter (IPC) or talc pleurodesis. RECENT FINDINGS:Administration of graded talc through an IPC offers an incre...

journal_title：Current opinion in pulmonary medicine

authors： Dipper A,Bhatnagar R,Maskell N

更新日期：2019-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The use of inhaled corticosteroids is one of the most controversial issues in COPD pharmacotherapy. Experts disagree about the benefits and harms of ICS for patients with COPD, yet a majority of patients with COPD are being treated with inhaled corticosteroids. This is a review of the most recent lite...

journal_title：Current opinion in pulmonary medicine

authors： Highland KB

更新日期：2004-03-01 00:00:00

abstract：PURPOSE OF REVIEW:After the disappointing results of lung cancer screening trials conducted in the 1960s to the 1980s, a renewed interest in lung cancer screening emerged in the 1990s with the development of new technologies such as low-dose spiral CT. The literature regarding screening with biomarkers and CT continues...

journal_title：Current opinion in pulmonary medicine

authors： Manser R

更新日期：2004-07-01 00:00:00

abstract：:Lung volume reduction surgery (LVRS) is a palliative surgical procedure for patients with severe emphysema. Resection of nonfunctional emphysematous lung tissue has been reported to relieve breathlessness and to improve quality of life for many patients by improving lung elastic recoil, respiratory muscle function, an...

journal_title：Current opinion in pulmonary medicine

authors： Meyer KC,Cornwell RD,Love RB

更新日期：2000-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines the current reports, the evidence and the issues surrounding the use of non-invasive ventilation (NIV) for the treatment of chronic obstructive pulmonary disease (COPD) in both the acute and domiciliary setting. RECENT FINDINGS:With the increasing use of NIV, more recent studies ...

journal_title：Current opinion in pulmonary medicine

authors： Ramsay M,Hart N

更新日期：2013-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Lung cancer is the leading cause of cancer mortality in men and women. Most patients present with advanced disease and face significant morbidity, with many reporting distressing symptoms throughout the course of their illness. The purpose of this review is to highlight the recent studies that support...

journal_title：Current opinion in pulmonary medicine

authors： Shin J,Temel J

更新日期：2013-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Bronchial and bronchiolar abnormalities in interstitial lung diseases (ILDs) are an issue often underestimated. However, new interstitial patterns with bronchiolar involvement are being described and the concept is still evolving. The scope of this review is to introduce a comprehensive approach to ai...

journal_title：Current opinion in pulmonary medicine

authors： Pappas K

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma is a heterogeneous disorder presenting with many phenotypes. Precise phenotypic definition has eluded the medical research community for years, despite recognition of different disease subtypes. Improved phenotypic characterization and knowledge of underlying pathobiology is necessary for linka...

journal_title：Current opinion in pulmonary medicine

authors： Kiley J,Smith R,Noel P

更新日期：2007-01-01 00:00:00

abstract：:Chronic airway inflammation is considered responsible for symptoms and disorders of airway function associated with asthma. This process is the target of anti-inflammatory therapy, so a number of standardized, noninvasive techniques have been developed to assess it. More recent approaches include the measurement of ex...

journal_title：Current opinion in pulmonary medicine

authors： Wilson N

更新日期：2002-01-01 00:00:00

abstract：:Although asthma is considered to be an inflammatory disease of the airways, neural mechanisms remain very important. Neural control of airways is far more complex than has been previously recognized. In addition to the classic neural pathways, the nonadrenergic, noncholinergic pathway has been described in the airways...

journal_title：Current opinion in pulmonary medicine

authors： Choi DC,Kwon OJ

更新日期：1998-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Medical thoracoscopy provides the physician a window into the pleural space. The procedure allows biopsy of the parietal pleura under direct visualization with good accuracy. In addition, it achieves therapeutic goals of fluid drainage, guided chest tube placement, and pleurodesis. RECENT FINDINGS:Co...

journal_title：Current opinion in pulmonary medicine

authors： Lee P,Mathur PN

更新日期：2016-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This article aims to review the most recent proteomic findings in tissue and biological fluids and application of new technologies for the study of interstitial lung diseases. RECENT FINDINGS:New insights into lung cell biology as well as novel pathogenetic pathways of different interstitial lung dis...

journal_title：Current opinion in pulmonary medicine

authors： Rottoli P,Bargagli E,Landi C,Magi B

更新日期：2009-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma outcomes constitute the cornerstone of asthma clinical research. Despite their known importance, it has been difficult for researchers to standardize these outcomes in large part because of the heterogeneity of the disease. This review seeks to provide an overview of recent recommendations for ...

journal_title：Current opinion in pulmonary medicine

authors： Parulekar AD,Alobaidy A,Hanania NA

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF REVIEW:There has been much recent interest in the use of macrolide antibiotics as chronic suppressive therapy in patients with cystic fibrosis. Three recent randomized, placebo-controlled trials have been conducted. RECENT FINDINGS:All three trials used similar regimens of azithromycin, and lung function im...

journal_title：Current opinion in pulmonary medicine

authors： Saiman L

更新日期：2004-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Although known for several decades, catamenial pneumothorax has been considered until recently as an extremely rare entity. The condition is now more easily recognized and several studies have been published, with somewhat relevant discrepancies with respect to etiologic, epidemiologic, and management...

journal_title：Current opinion in pulmonary medicine

authors： Alifano M

更新日期：2010-07-01 00:00:00

abstract：:The goal of management of patients with respiratory failure is to restore them to a state of quiet breathing, without complication. This goal is often achieved by pharmacotherapy alone. Inhaled albuterol sulfate, oxygen, and systemic corticosteroids are mainstays of acute care drug management, whereas other data suppo...

journal_title：Current opinion in pulmonary medicine

authors： Gluckman TJ,Corbridge T

更新日期：2000-01-01 00:00:00

abstract：:Small cell lung cancer (SCLC) accounts for 20% to 25% of bronchogenic carcinoma cases. Combination chemotherapy offers the best chance for improved survival. Cisplatin plus etoposide appears to be the most reasonable choice for first line therapy. Increasing dose intensity, although sometimes associated with higher re...

journal_title：Current opinion in pulmonary medicine

authors： Adjei AA

更新日期：2000-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) represent two of the most prevalent chronic respiratory disorders and cardiovascular diseases are major co-morbidities in both. Co-existence of both disorders (overlap syndrome) occurs in 1% of adults and overlap patients h...

journal_title：Current opinion in pulmonary medicine

authors： Lee R,McNicholas WT

更新日期：2011-03-01 00:00:00

abstract：:Patients with acute deep vein thrombosis (DVT) were treated with a body-weight independent dosage of 2 x 8000 aXa IU low-molecular-weight heparin (LMWH) Certoparin. After the subcutaneous administration of 8000 IU Certoparin, pharmacodynamic parameters did not differ between patients and healthy volunteers, and the AU...

journal_title：Current opinion in pulmonary medicine

authors： Harenberg J

更新日期：2002-09-01 00:00:00

abstract：:The bronchiolitides can be categorized broadly as constrictive or proliferative, each with characteristic CT features. The cardinal CT signs of constrictive bronchiolitis are mosaic perfusion, enhanced on expiratory CT scan and variably associated with bronchiectasis and, less frequently, centrilobular branching struc...

journal_title：Current opinion in pulmonary medicine

authors： Wells AU

更新日期：1998-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Pulmonary fibrosis is a reparative response characterized by accumulation of extracellular matrix in the lung parenchyma that may be observed in end-stage sarcoidosis. This article will discuss the recent advancements in the understanding of the pathogenesis of pulmonary fibrosis in sarcoidosis in com...

journal_title：Current opinion in pulmonary medicine

authors： Shigemitsu H,Azuma A

更新日期：2011-09-01 00:00:00

abstract：:The pleural space in healthy humans was thought to contain a few milliliters of fluid, based on extrapolation from animal studies. However, because of the obvious technical difficulties in atraumatically retrieving such a small volume of fluid, the exact volume and cellular content of human pleural fluid has not been ...

journal_title：Current opinion in pulmonary medicine

authors： Noppen M

更新日期：2001-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the current use of oral corticosteroids (OCS) as a chronic treatment in patients with severe asthma and as a rescue treatment for patients presenting with acute exacerbations. RECENT FINDINGS:Airways disease is responsible for the bulk of OCS use in the community and considerable OCS-assoc...

journal_title：Current opinion in pulmonary medicine

authors： Pavord ID

更新日期：2019-01-01 00:00:00

abstract：:The progressive breakdown of the cell-mediated immunity, which characterizes the natural history of HIV infection, invariably leads to the development of miscellaneous opportunistic infections or neoplasms involving a number of tissues, including the respiratory tract. In particular, given the extent and the severity ...

journal_title：Current opinion in pulmonary medicine

authors： Semenzato G,Agostini C

更新日期：1995-09-01 00:00:00