Corticosteroids in idiopathic pulmonary fibrosis.

abstract：:The neurotrophins are a family of peptides that promote survival, growth, and differentiation of neurons. Neurotrophins may also influence the function of nonneuronal cell types, including immune cells. The development and maintenance of asthma is thought to involve the nervous system and the immune system, but the ro...

journal_title：Current opinion in pulmonary medicine

authors： Carr MJ,Hunter DD,Undem BJ

更新日期：2001-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The Sleep Heart Health Study began in 1994 as a prospective cohort study of cardiovascular disease. The results of longitudinal analysis are not yet available, but numerous analyses of cross-sectional data have been published. This review provides an overview of study results so far. RECENT FINDINGS:...

journal_title：Current opinion in pulmonary medicine

authors： Gottlieb DJ

更新日期：2008-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Pleural effusions are frequent in the context of acute idiopathic pericarditis and following pericardiotomy, but they have seldom been characterized. This review summarizes their most relevant clinical features. RECENT FINDINGS:In acute idiopathic pericarditis, pleural effusions tend to be left-sided...

journal_title：Current opinion in pulmonary medicine

authors： Porcel JM

更新日期：2017-07-01 00:00:00

abstract：:Lung volume reduction surgery (LVRS) is a palliative surgical procedure for patients with severe emphysema. Resection of nonfunctional emphysematous lung tissue has been reported to relieve breathlessness and to improve quality of life for many patients by improving lung elastic recoil, respiratory muscle function, an...

journal_title：Current opinion in pulmonary medicine

authors： Meyer KC,Cornwell RD,Love RB

更新日期：2000-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this article is to provide understanding of renal sarcoidosis, the different types of renal sarcoidosis, disease burden of renal involvement, and treatment options. RECENT FINDINGS:The frequency of renal involvement seems to be underestimated, but renal sarcoidosis represents a relevan...

journal_title：Current opinion in pulmonary medicine

authors： Bergner R,Löffler C

更新日期：2018-09-01 00:00:00

abstract：:Patients infected with HIV are at risk of developing a variety of infectious and malignant pleuropulmonary disorders. The three most common causes of AIDS-related pleural effusions are parapneumonic effusions or empyemas, tuberculosis, and Kaposi's sarcoma. However, the relative frequency of these conditions varies fr...

journal_title：Current opinion in pulmonary medicine

authors： Hamm H,Matthys H

更新日期：1997-07-01 00:00:00

abstract：:Some time ago, the Th2 cytokine, interleukin (IL)-13, was identified as a critical regulator of the allergic response. Initial studies in animal models of disease provided compelling evidence that IL-13, independent from other Th2 cytokines, was necessary and sufficient to induce all features of allergic asthma. This ...

journal_title：Current opinion in pulmonary medicine

authors： Wills-Karp M,Chiaramonte M

更新日期：2003-01-01 00:00:00

abstract：:The most common syndromes associated with obstructive lung disease are asthma and chronic obstructive pulmonary disease (COPD). Evidence for a viral etiology of asthmatic exacerbations is well known, but evidence for a role for viruses in COPD exacerbation is just emerging. Viruses may cause chronic infection in both ...

journal_title：Current opinion in pulmonary medicine

authors： Seemungal TA,Wedzicha JA

更新日期：2003-03-01 00:00:00

abstract：:Antibiotic resistance in respiratory pathogens has dramatically increased during recent years. Resistance to penicillin and multiple antimicrobial agents in pneumococci and resistance to ampicillin in Moraxella catarrhalis and Haemophilus influenzae, as a result of betalactamase production, have become highly prevalen...

journal_title：Current opinion in pulmonary medicine

authors： Dominguez MA,Pallares R

更新日期：1998-05-01 00:00:00

abstract：PURPOSE OF REVIEW:A relatively new class of CD4 expressing T cells that also express and release interleukin-17 (Th17 cells) is gaining attention based on their capacity to regulate inflammatory responses in a spectrum of chronic autoimmune diseases. The purpose of this review is to consider recent studies relating to ...

journal_title：Current opinion in pulmonary medicine

authors： Crouser ED

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Telomere attrition has been proposed as one of the aging hallmarks in pulmonary fibrosis. Telomere shortening and telomerase gene mutations have been widely evaluated in recent years. Reduced telomere length may be identified in a quarter of patients with sporadic idiopathic pulmonary fibrosis (IPF) a...

journal_title：Current opinion in pulmonary medicine

authors： Molina-Molina M,Borie R

更新日期：2018-09-01 00:00:00

abstract：:In reviewing recent advances in upper respiratory tract infections, we focus on five key topics. First, the use of ribavirin in the treatment of respiratory syncytial virus infection has been limited to the immunosuppressed. Prophylaxis in high-risk patients with specific immunoglobulin is effective and a new monoclon...

journal_title：Current opinion in pulmonary medicine

authors： Moore DA,Sharland M,Friedland JS

更新日期：1999-05-01 00:00:00

abstract：:Uvulopalatopharyngoplasty has limited efficacy in treating obstructive sleep apnea, with excellent results achieved in fewer than half of patients who undergo this procedure. Attempting to select patients who have only retropalatal collapse of the pharynx increases the likelihood of a successful outcome. Although this...

journal_title：Current opinion in pulmonary medicine

authors： Sher AE

更新日期：1995-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Idiopathic pulmonary fibrosis (IPF) is a progressive, invariably fatal condition with a median survival from diagnosis of only 3 years. Despite improvements in disease understanding, challenges remain in establishing a diagnosis and predicting prognosis in individual patients. Furthermore, limited und...

journal_title：Current opinion in pulmonary medicine

authors： Maher TM

更新日期：2013-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Time to clinical worsening (TTCW) can be used to assess disease progression associated with pulmonary arterial hypertension (PAH). As a consequence, it is highly relevant to patients, clinicians, and regulatory agencies. The majority of clinical trials of PAH-specific drug therapies have included TTCW...

journal_title：Current opinion in pulmonary medicine

authors： Galiè N,Simonneau G,Barst RJ,Badesch D,Rubin L

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The Burkholderia cepacia complex is comprised of a group of related bacterial species that are capable of causing life-threatening respiratory tract infection in persons with cystic fibrosis. This article reviews advances in our understanding of Burkholderia cepacia complex infection in cystic fibrosi...

journal_title：Current opinion in pulmonary medicine

authors： Lipuma JJ

更新日期：2005-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Classic descriptions of chronic obstructive pulmonary disease (COPD) centered on its impact on respiratory function. It is currently recognized that comorbidities contribute to the severity of symptoms and COPD progression. Understanding COPD-comorbidities associations could provide innovative treatme...

journal_title：Current opinion in pulmonary medicine

authors： Brown JP,Martinez CH

更新日期：2016-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Ever since sarcoidosis was first described, its relationship with tuberculosis has been debated. Whereas some consider sarcoidosis and tuberculosis as two extremes of the same disease process, other researchers have negated the role of mycobacteria in causation of sarcoidosis. Whether or not linked ca...

journal_title：Current opinion in pulmonary medicine

authors： Gupta D,Agarwal R,Aggarwal AN,Jindal SK

更新日期：2012-09-01 00:00:00

abstract：:This review summarizes the recent literature published on the microbiology, diagnosis, and medical and surgical management of acute and chronic frontal sinus disease. Two retrospective studies investigated the microbiology of frontal sinusitis in patients that underwent sinus surgery. Streptococcus pneumoniae, Haemoph...

journal_title：Current opinion in pulmonary medicine

authors： Brook I

更新日期：2003-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Cancer patients with venous thromboembolism (VTE) are at increased risk of mortality. Estimating the risks for specific causes of death may help to weigh the risks and benefits of different therapeutic strategies in an individual patient. RECENT FINDINGS:In the Registro Informatizado de la Enfermedad...

journal_title：Current opinion in pulmonary medicine

authors： Trujillo-Santos J,Monreal M

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Symptoms of anxiety and depression are prevalent in at least 20-40% of patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) and are known to affect prognosis and worsen quality of life. This review examines whether pulmonary rehabilitation can effectively improve psychological...

journal_title：Current opinion in pulmonary medicine

authors： Coventry PA

更新日期：2009-03-01 00:00:00

abstract：PURPOSE OF REVIEW:In many cases, the specific pathogen responsible for a respiratory infection is not identified and can lead to improper medical treatment, increased duration of illness, and possibly contributes to the development of antibiotic resistance. Molecular-based diagnostic methodologies have significantly im...

journal_title：Current opinion in pulmonary medicine

authors： Lednicky JA,Rayner JO

更新日期：2006-05-01 00:00:00

abstract：:Diabetes is a common complication of cystic fibrosis. Because it is associated with increased morbidity and mortality, prompt diagnosis and aggressive management of cystic fibrosis-related diabetes is important. The Cystic Fibrosis Foundation held a consensus conference in 1998 to define the standards of care for pati...

journal_title：Current opinion in pulmonary medicine

authors： Riggs AC,Seaquist ER,Moran A

更新日期：1999-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article is to examine the evidence for the effectiveness of systemic corticosteroids in managing acute asthma in children as it relates to the timing of its administration. RECENT FINDINGS:Three themes relevant to the timing of systemic corticosteroid administration as it relates to m...

journal_title：Current opinion in pulmonary medicine

authors： Bhogal SK

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Malignant pleural effusion (MPE) is common. However, regardless of the differences between patients, their underlying cancer type, and pleural fluid characteristics, management options are often limited. These have not advanced significantly over the last 80 years since pleurodesis was first described...

journal_title：Current opinion in pulmonary medicine

authors： Davies HE,Lee YC

更新日期：2013-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypersensitivity pneumonitis (HP), also known as extrinsic allergic alveolitis, is a granulomatous, inflammatory disease of the lungs caused by the inhalation of antigenic organic particles or fumes. The disease may present as an acute, subacute, or chronic illness. Episodes of acute and subacute HP u...

journal_title：Current opinion in pulmonary medicine

authors： Mohr LC

更新日期：2004-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Pleural effusions are a common finding in the nearly six million Americans diagnosed with heart failure. This review focuses on the historical, present and potential future trends in the management of such benign pleural effusions. RECENT FINDINGS:The management of symptomatic pleural effusions, in g...

journal_title：Current opinion in pulmonary medicine

authors： Freeman RK

更新日期：2015-07-01 00:00:00

abstract：:Apoptosis, also known as activation-induced cell death or programmed cell death, is an active suicide mechanism that is involved in normal tissue turnover during embryogenesis and adult life. There are many examples of apoptosis in the immune system, including programmed cell death of T cells during negative intrathym...

journal_title：Current opinion in pulmonary medicine

authors： Agostini C,Perin A,Semenzato G

更新日期：1998-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Heparin-induced thrombocytopenia is a severe side effect of treatment with unfractionated heparin. The relation of low-molecular-weight heparin to heparin-induced thrombocytopenia is less well understood. This review will summarize what is known about the similarities and differences between thrombocy...

journal_title：Current opinion in pulmonary medicine

authors： Walenga JM,Prechel M,Jeske WP,Bakhos M

更新日期：2005-09-01 00:00:00

abstract：:Chronic airway inflammation is considered responsible for symptoms and disorders of airway function associated with asthma. This process is the target of anti-inflammatory therapy, so a number of standardized, noninvasive techniques have been developed to assess it. More recent approaches include the measurement of ex...

journal_title：Current opinion in pulmonary medicine

authors： Wilson N

更新日期：2002-01-01 00:00:00