Abstract：
:An antibody to the 96 kD alpha-subunit of the Na+, K+-ATPase from Bufo marinus has been used in immunostaining rat kidney and salivary glands. Intense staining was observed on basolateral membranes of distal tubules of the kidney and striated ducts of the three major salivary glands. Less intense staining was seen on the basolateral membranes of parotid acinar cells, but no staining was seen on the acinar cells of submandibular or sublingual glands. These sites of staining have been shown, by other methods, to posses substantial Na+, K+-ATPase, indicating that the antibody recognizes antigenic determinants of the sodium pump highly conserved in the course of evolution. In addition, staining with this antibody was observed at the apical region of cells of the proximal straight tubule and of the papillary collecting duct in the kidney. Absorption studies suggest that the apical antigenic determinants are the same or closely related to each other but are distinct from basolateral antigenic determinants.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Graves JS,Inabnett T,Geering K,Simson JAdoi
10.1007/BF00223153subject
Has Abstractpub_date
1989-10-01 00:00:00pages
137-45issue
1eissn
0302-766Xissn
1432-0878journal_volume
258pub_type
杂志文章abstract：:The immunocytochemical localization of bovine oviduct-specific glycoproteins was investigated by light and electron microscopy. Using monoclonal antibodies (MAbs) specific for bovine oviductal glycoproteins, 3 regions (fimbriae, ampulla, and isthmus) of the epithelium in the bovine oviduct we studied during the follic...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00327983
更新日期：1993-10-01 00:00:00
abstract：:The pineal gland structure and ultrastructure in the Northern (Blarina brevicauda) and Southern short-tailed shrew (Blarina carolinensis) are described by light and electron microscopy. Results observed were similar to other mammals of Insectivora described previously, specifically, the hedgehog (Erinaceus europaeus) ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-018-2897-8
更新日期：2018-12-01 00:00:00
abstract：:A total of 20 Golgi-impregnated cone horizontal cells of Nannacara anomala (Cichlidae) were studied in alternating semi- and ultrathin sections in order to examine their connections with the overlying square mosaic of equal double and central single cones. Cone horizontal cells exhibiting three types of processes: (a)...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00220825
更新日期：1976-11-24 00:00:00
abstract：:In humans, pathogenesis in cyclosporine A (CsA)-induced gingival overgrowth (GO) includes the accumulation of extracellular matrix (ECM) constituents, viz., collagen type-1 and type-3 and proteoglycans, in subgingival connective tissue. However, whether this increase is associated with alterations of molecules pivotal...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0200-x
更新日期：2006-09-01 00:00:00
abstract：:iASPP (inhibitory member of the ASPP family), the conserved key inhibitor of p53, is overexpressed and plays an important oncogenetic role in many human cancers. However, its function in cervical cancer remains unknown. The objective of this study was to investigate the expression and clinical relevance of iASPP in ce...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-013-1569-y
更新日期：2013-05-01 00:00:00
abstract：:Previous neurohistological studies have been extended to include the structures contained solely or mainly within the junctional esophageal segment which may play an important role in the sphincter mechanism. The main findings were: 1) a progressive cranio-caudal thickening of the muscularis mucosae; 2) a conspicuous ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215998
更新日期：1976-05-26 00:00:00
abstract：:The size of various tubes within tubular organs such as the lung, vascular system and kidney must be finely tuned for the optimal delivery of gases, nutrients, waste and cells within the entire organism. Aberrant tube sizes lead to devastating human illnesses, such as polycystic kidney disease, fibrocystic breast dise...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-013-1673-z
更新日期：2013-11-01 00:00:00
abstract：:The cellular localization of renin was examined in the kidneys of some amphibians of the genus Bufo by immunoperoxidase and immunofluorescence techniques with an antiserum to renin isolated from the submandibular gland of the mouse. Immunoreactivity could be demonstrated in the media cells of the afferent arterioles (...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219248
更新日期：1985-01-01 00:00:00
abstract：:Box jellyfish have the most elaborate sensory system and behavioural repertoire of all cnidarians. Sensory input largely comes from 24 eyes situated on four club-shaped sensory structures, the rhopalia, and behaviour includes obstacle avoidance, light shaft attractance and mating. To process the sensory input and conv...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0393-7
更新日期：2007-07-01 00:00:00
abstract：:Correlations between the presence of surface coat and immobilization antigen of Paramecium tetraurelia were studied. Supravital, partial removal of the surface coat resulted in accelerated response of monobacterially and axenically grown cells to the homologous antiserum. Ciliates pretreated with trypsin or pronase (0...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219984
更新日期：1977-07-11 00:00:00
abstract：:The thoracic legs of the moth Manduca sexta acquire a new form and develop a new complement of sensory organs and muscles during metamorphosis from larva to adult. Because of our interest in the reorganization of neural circuitry and the acquisition of new behaviors during metamorphosis, we are characterizing sensory ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00318442
更新日期：1990-02-01 00:00:00
abstract：:The three-dimensional structure of the mitochondria and sarcoplasmic reticulum (SR) in the three types of twitch fibers, i.e., the red, white and intermediate skeletal muscle fibers, of the vastus lateralis muscle of the Japanese meadow frog (Rana nigromaculata nigromaculata Hallowell) was examined by high resolution ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218939
更新日期：1987-12-01 00:00:00
abstract：:Gastrin stimulates gastric acid secretion by acting on the cholecystokinin B/gastrin receptor (CCK-BR). The localization of this receptor at the cellular level showed conflicting results in animal studies and has not been described in man by immunohistochemistry. The aim of the present study is to characterize the pre...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004419900114
更新日期：2000-02-01 00:00:00
abstract：:A histological examination of 205 fish representing four cyprinid species from a site 2.5 miles north of Wheeling, West Virginia, on the Ohio River revealed large (2--4 micron) cuboidal intranuclear inclusion bodies (NIB's) within neurons in the cranial and spinal ganglia of three species. Because the minnows had been...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00210112
更新日期：1981-01-01 00:00:00
abstract：:Induction of HIF-1α by oxygen limitation promotes increased phosphorylation and catalytic depression of mitochondrial pyruvate dehydrogenase (PDH) and an enhanced glycolytic poise in cells. Cobalt chloride and desferrioxamine are widely used as mimics for hypoxia because they increase the levels of HIF-1α. We evaluate...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-012-1517-2
更新日期：2013-01-01 00:00:00
abstract：:Uptake of uteroglobin (UGL) by day-6 rabbit blastocysts and the intracellular fate of this protein were studied by light- and electron-microscopic autoradiography, immunocytochemistry and acid-phosphatase cytochemistry. UGL, labelled with N-succinimidyl-(2-3-3H)-propionate, was administered to embryos in vitro for 25 ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00305254
更新日期：1990-12-01 00:00:00
abstract：:The morphology of the antennal hair-sensilla of Periplaneta americana, their distribution and frequency on the antennal flagellum have been examined by transmission- and scanning-electron microscopy. The types of sensilla were distinguished with respect to physiologically relevant criteria such as wall structure and n...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00223221
更新日期：1978-07-13 00:00:00
abstract：:The cellular response of non-neuronal elements of the pyramidal cell layer of the rat hippocampus, especially the area CA3, was observed electron microscopically following destruction of this formation by means of intraventricular administration of kainic acid (KA). The neuroglial cell types responding to the KA-induc...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00238652
更新日期：1981-01-01 00:00:00
abstract：:The gene encoding H1t, a testicular variant of histone H1, is expressed in mammals during spermatogenesis. Northern blot and in situ hybridization has detected H1t mRNA only at the stage of pachytene spermatocytes. We have extended this analysis to more sensitive approaches and demonstrate, by RNase protection and ele...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050986
更新日期：1998-01-01 00:00:00
abstract：:Evidence has already been adduced suggesting that an increase in microtubular number occurs in the tractus hypophyseus of rats stressed by the administration of hypertonic saline, and of rats with congenital diabetes insipidus (CDI). Since the tractus hypophyseus in these animals shows high secretory activity, it seem...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219611
更新日期：1976-06-28 00:00:00
abstract：:TFF-peptides (formerly P-domain peptides, trefoil factors) are typical secretory products of mucin-producing cells and seem to influence the rheological properties of mucous gels. Here, localization studies of TFF-peptides in human salivary glands are presented. Expression studies (polymerase chain reaction) revealed ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004419900087
更新日期：1999-10-01 00:00:00
abstract：:Pituitary adenylate cyclase-activating polypeptide (PACAP) is the latest member of the vasoactive intestinal polypeptide (VIP) family of neuropeptides present in nerve fibres in many peripheral organs. Using double immunohistochemistry, with VIP as a marker for intrinsic innervation and calcitonin-gene related peptide...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004419900124
更新日期：2000-01-01 00:00:00
abstract：:The subcommissural organ secretes N-linked complex-type glycoproteins into the cerebrospinal fluid. These glycoproteins condense to form Reissner's fiber (RF), which extends along the fourth ventricle and central canal of the spinal cord. A set of three monoclonal antibodies (Mabs 3E6, 3B1, and 2A5) has been obtained ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050672
更新日期：1996-10-01 00:00:00
abstract：:We have recently examined the electrophysiology and ultrastructure of approximately 100 tactile spines from the metathoracic legs of adult cockroaches. In only one animal the single sensory neuron that innervates the spine was replaced with a pair of apparently identical neurons which we believe were both functional. ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216522
更新日期：1984-01-01 00:00:00
abstract：:Biocytin, recently introduced in neuroanatomical studies, was used as a retrograde tract tracer in combination with immunofluorescence in order to analyse the neurochemical characters of some central neuronal projections to the pars intermedia in two amphibian species, the anuran Rana esculenta and the urodele Trituru...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050754
更新日期：1997-02-01 00:00:00
abstract：:We have examined IgG Fc receptor (FcR) activity of human and rabbit arachnoid granulations and leptomeninges using antibody (IgG)-coated erythrocytes (EIgG), covalently crosslinked IgG dimers, trimers and oligomers, immune complexes, aggregated Fc fragments and a monoclonal anti-human neutrophil Fc receptor antibody, ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216489
更新日期：1987-06-01 00:00:00
abstract：:DNA distribution in mouse, rabbit and bull spermatids was analyzed by electron microscopy, after using a Feulgen-like HCl-osmium ammine procedure, and after immunocytochemistry with anti-DNA antibodies. In addition, nucleic acids were visualized with the intercalating dye ethidium bromide and phosphotungstic acid. The...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00340875
更新日期：1991-09-01 00:00:00
abstract：:Clusterin (CLU) is an extracellular chaperone protein that is implicated in diverse physiological and pathophysiological cellular processes. CLU expression is upregulated in response to cellular stress and under certain conditions, such as neurodegenerative disease and cancer. CLU primarily functions as a chaperone th...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-017-2650-8
更新日期：2017-10-01 00:00:00
abstract：:Scanning electrom microscopy of the ventricular surface of the pars ventralis of the tuber cinereum of the frog Rana temporaria shows that it can be divided in (1) a dorsolateral area, characterized by the presence of very numerous large, solid, bulbous protrusions (2) a medial area, where the large bulbous structures...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00231997
更新日期：1975-05-27 00:00:00
abstract：:The fan-shaped body is the largest substructure of the central complex in Drosophila melanogaster. Two groups of large-field neurons that innervate the fan-shaped body, viz., F1 and F5 neurons, have recently been found to be involved in visual pattern memory for "contour orientation" and "elevation" in a rut-dependent...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-009-0781-2
更新日期：2009-06-01 00:00:00
