Abstract:
:The thoracic legs of the moth Manduca sexta acquire a new form and develop a new complement of sensory organs and muscles during metamorphosis from larva to adult. Because of our interest in the reorganization of neural circuitry and the acquisition of new behaviors during metamorphosis, we are characterizing sensory elements of larval and adult legs so that we may determine the contribution of new sensory inputs to the changes in behaviors. Here we describe the sensory structures of adult legs using scanning electron microscopy to view the external sensilla and cobalt staining to examine innervation by underlying sensory neurons. We find that, in contrast to larval legs, the adult legs are covered with a diverse array of sensilla. All three pairs of thoracic legs contain scattered, singly innervated scalelike sensilla. Campaniform sensilla occur singly or in clusters near joints. Hair plates, consisting of numerous singly innervated hairs, are also present near joints. Other more specialized sensilla occur on distal leg segments. These include singly innervated spines, two additional classes of singly innervated hairs, and three classes of multiply innervated sensilla. Internal sensory organs include chordotonal organs, subgenual organs, and multipolar joint receptors.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Kent KS,Griffin LMdoi
10.1007/BF00318442subject
Has Abstractpub_date
1990-02-01 00:00:00pages
209-23issue
2eissn
0302-766Xissn
1432-0878journal_volume
259pub_type
杂志文章abstract::Glaucoma, a disease of the optic nerve and retina, causes blindness in millions of people worldwide. Currently available therapies for this disease only attempt to reduce intraocular pressure, the major risk factor, without addressing the associated optic neuropathy and retinopathy. Development of glaucoma neuroprotec...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-013-1584-z
更新日期:2013-08-01 00:00:00
abstract::The lymphatic organization and its relationship to the vascular system in the rat small intestine was studied by scanning electron microscopy of corrosion casts and freeze-fractured tissues, and by light microscopy of injected preparations. The villus possessed 3-10 or more central lacteals depending upon the villous ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218204
更新日期:1987-05-01 00:00:00
abstract::The expression of the gene for vasoactive intestinal polypeptide (VIP) and peptide histidine methionine (PHM) in the human gastrointestinal tract was studied by in situ hybridization and Northern blotting for PHM/VIP mRNA and immunocytochemistry using specific antisera against the bioactive peptides PHM and VIP. In th...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00306108
更新日期:1994-05-01 00:00:00
abstract::The distribution of luteinizing hormone-releasing hormone (LHRH) was studied in the rat and mouse brain by means of light and electron microscopic immunohistochemistry using the peroxidase-antiperoxidase method. An immunoreactive product to LHRH antiserum was found near the blood vessels of the vascular organ of the l...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233914
更新日期:1979-03-19 00:00:00
abstract::Pituitary adenylate cyclase-activating polypeptide (PACAP) is the latest member of the vasoactive intestinal polypeptide (VIP) family of neuropeptides present in nerve fibres in many peripheral organs. Using double immunohistochemistry, with VIP as a marker for intrinsic innervation and calcitonin-gene related peptide...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004419900124
更新日期:2000-01-01 00:00:00
abstract::The three-dimensional ultrastructure of the pineal body of the rat is described on the basis of freeze-fractured preparations. The pineal capsule consists of irregular cells with very flat and perforated processes. Through these openings, extremely branched canaliculi, extending to almost every pineal cell, communicat...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00238052
更新日期:1979-09-02 00:00:00
abstract::We have tested the suggestion that the reported increase, in hypoxic rats, in the number of lung endocrine cells immunoreactive for the regulatory peptide CGRP is caused by an accumulation of peptide within the cells which renders them more detectable, rather than by a real increase in proliferation. The incorporation...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00338049
更新日期:1992-04-01 00:00:00
abstract::Daily fluctuations of nucleoli and nucleolar fibrillar centres in neurosecretory cells from the supraoptic nucleus (SON) were investigated in rats artificially synchronized for 3 weeks to a set 12 h light/12 h dark cycle with free access to food and water. Group of 3 animals were sacrificed by intracardiac perfusion e...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222351
更新日期:1985-01-01 00:00:00
abstract::During tooth development, the inner and outer enamel epithelia fuse by mitotic activity to produce a bilayered epithelial sheath termed Hertwig's epithelial root sheath (HERS). The epithelial rests of Malassez (ERM) are the developmental residues of HERS and remain in the adult periodontal ligament (PDL). Although the...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-010-1076-3
更新日期:2010-12-01 00:00:00
abstract::In the small intestine of the pig, neuromedin U (NMU)-immunoreactivity was mainly confined to the nerve plexus of the inner submucosal and mucosal regions. After colchicine treatment, a high number of immunoreactive nerve cell bodies was observed in the plexus submucosus internus (Meissner), whereas only a low number ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00239453
更新日期:1989-11-01 00:00:00
abstract::Progenitor stem cells have been identified, isolated and characterized in numerous tissues and organs. However, their therapeutic potential and the use of these stem cells remain elusive except for a few progenitor cells from bone marrow, umbilical cord blood, eyes and dental pulp. The use of bone marrow-derived hemat...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-012-1471-z
更新日期:2012-10-01 00:00:00
abstract::The gross structure as well as the neuronal and non-neuronal components of the lamina ganglionaris of the locust Schistocerca gregaria are described on the basis of light- and electron-microscopical preparations of Golgi (selective silver) and ordinary histological preparations. The array of optic cartridges within th...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233626
更新日期:1981-01-01 00:00:00
abstract::Enzymatic activities of calcium-magnesium dependent adenosine triphosphatase (Ca-ATPase) and nonspecific alkaline phosphatase (ALPase) were localized at the initial calcification sites of dentin and enamel of rat incisor teeth using electron-microscopic cytochemistry. Ca-ATPase was localized in the Golgi cisternae, cy...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221856
更新日期:1986-01-01 00:00:00
abstract::In an attempt to determine the neural control of pancreatic D cells, the pancreatic islets of the domestic fowl were examined electron microscopically from 1 to 28 days after abdominal vagotomy. Exocytotic release of many secretory granules from D cells occurred one day after vagotomy. Rough endoplasmic reticulum deve...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233732
更新日期:1980-01-01 00:00:00
abstract::Orexins (OxA and OxB) and their receptors (Ox1R and Ox2R), originally detected in the hypothalamus, have also been localized in multiple cerebral areas and peripheral organs. Thus, in addition to their central function in the regulation of food intake, arterial blood pressure, heart rate, sleep/wake cycle, sexual beha...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-012-1394-8
更新日期:2012-06-01 00:00:00
abstract::The protein tyrosine phosphatase interacting protein 51 (PTPIP51) is thought to regulate crucial cellular functions such as mitosis, apoptosis, migration, differentiation and communication between organelles as a scaffold protein. These diverse functions are modulated by the tyrosine/serine phosphorylation status of P...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-016-2508-5
更新日期:2017-06-01 00:00:00
abstract::In Rana temporaria tadpoles, fluorescent fibres appear in the prospective eminentia mediana, the pars intermedia and the pars distalis at Gosner's stage 25. During prometamorphosis the amount of fluorescent material increases around the developing primary capillary plexus in the eminentia mediana. In the pars intermed...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00220236
更新日期:1976-09-01 00:00:00
abstract::Ultrastructural post-embedding immuno-gold techniques were applied to the supraoptic nucleus and the neurohypophysis of mice and rats. The primary antibodies were three different monoclonal antineurophysins, used in protein A-gold and immunoglobulin-gold procedures. Conventional plastic embedding as well as hydrophili...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221868
更新日期:1986-01-01 00:00:00
abstract::A histological examination of 205 fish representing four cyprinid species from a site 2.5 miles north of Wheeling, West Virginia, on the Ohio River revealed large (2--4 micron) cuboidal intranuclear inclusion bodies (NIB's) within neurons in the cranial and spinal ganglia of three species. Because the minnows had been...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00210112
更新日期:1981-01-01 00:00:00
abstract::The presence, location and degree of immunoexpression of various microfilament (MF) and intermediate filament (IF) systems (actin, cytokeratins, desmin, vimentin) were studied in the excurrent ducts of the testis in sexually mature and active galliform (Japanese quail, domestic fowl, turkey) and anseriform (duck) bird...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-008-0631-7
更新日期:2008-08-01 00:00:00
abstract::The blood-brain barrier (BBB) protects the brain from toxic substances within the bloodstream and keeps the brain's homeostasis stable. On the other hand, it also represents the main obstacle in the treatment of many CNS diseases. Among different techniques, nanoparticles have emerged as promising tools to enhance bra...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-014-1819-7
更新日期:2014-03-01 00:00:00
abstract::Late erythroblasts and reticulocytes from bone marrow of male Wistar rats were studied by electron-microscopic stereology. Late erythroblasts with morphological signs of nuclear extrusion (EN + erythroblasts) and late erythroblasts without these signs (EN-erythroblasts) were analysed separately. The volumes of mitocho...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214924
更新日期:1985-01-01 00:00:00
abstract::A striking feature of vestibular hair cells is the polarized arrangement of their stereocilia as the basis for their directional sensitivity. In mammals, each of the vestibular end organs is characterized by a distinct distribution of these polarized cells. We utilized the technique of post-fixation transganglionic ne...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-010-0944-1
更新日期:2010-05-01 00:00:00
abstract::In vitro incubation of autonomic nerves with vinblastine sulphate (1 times 10(-4) M) caused a disappearance of microtubules within 15 min; during the following 15 min paracrystalline arrays appeared within the axons. An increase in the abundance of microfilaments was also observed, but these did not appear to arise fr...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00220136
更新日期:1976-02-25 00:00:00
abstract::Carotid bodies of ducks show no detectable changes in ultrastructure up to periods of four weeks following the removal of 2-3 cm of the cervical vagus (decentralization). This indicates that the majority, and possibily all the nerves terminating on the glomus cells are afferent (sensory) in nature. These nerve endings...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218494
更新日期:1975-11-19 00:00:00
abstract::High-density cultures are widely used as an in vitro model for studies of embryonic cartilage formation. In the present study we investigated the suitability of high-density cultures for the redifferentiation of dedifferentiated chondrocytes. When primary human chondrocytes were cultured in alginate beads, some cells ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-002-0562-7
更新日期:2002-06-01 00:00:00
abstract::Nitric oxide (NO) stimulates osteoblast differentiation, but whether NO contributes to odontoblast differentiation during dentin repair is unknown. By using reverse transcription/polymerase chain reaction and immunostaining, we investigated the gene expression and/or immunolocalization of endothelial NO synthase (eNOS...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-005-0003-5
更新日期:2007-04-01 00:00:00
abstract::Isotocinergic (IT) neurons show physiological and morphological characteristcs that are similar to those of the other preoptic neuroendocrine cells in the goldfish. Preoptic IT cells show resting membrane potentials of 20-55 mV, action potentials of up to 100 mV, and physiological evidence of axonal branching. Dye-mar...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00239217
更新日期:1979-10-02 00:00:00
abstract::Transforming growth factor beta (TGF-beta) is a major member of a cytokine family with pluripotent biological activity. In the liver, TGF-beta has pathophysiological significance with respect to hepatic fibrogenesis, regulation of liver cell growth, tumor development, and induction of hepatocellular apoptosis. We show...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050740
更新日期:1997-01-01 00:00:00
abstract::To identify anterior pituitary cell types containing GnRH binding sites and to study the internalization process of this peptide by target cells under physiological conditions, autoradiography was performed on rat anterior pituitaries removed at specific time intervals (2-60 min) after intravenous injection of mono-ra...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00216482
更新日期:1987-06-01 00:00:00