Abstract:
:Acetylene hydrochlorination is an important coal-based technology for the industrial production of vinyl chloride, however it is plagued by the toxicity of the mercury chloride catalyst. Therefore extensive efforts have been made to explore alternative catalysts with various metals. Here we report that a nanocomposite of nitrogen-doped carbon derived from silicon carbide activates acetylene directly for hydrochlorination in the absence of additional metal species. The catalyst delivers stable performance during a 150 hour test with acetylene conversion reaching 80% and vinyl chloride selectivity over 98% at 200 °C. Experimental studies and theoretical simulations reveal that the carbon atoms bonded with pyrrolic nitrogen atoms are the active sites. This proof-of-concept study demonstrates that such a nanocomposite is a potential substitute for mercury while further work is still necessary to bring this to the industrial stage. Furthermore, the finding also provides guidance for design of carbon-based catalysts for activation of other alkynes.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Li X,Pan X,Yu L,Ren P,Wu X,Sun L,Jiao F,Bao Xdoi
10.1038/ncomms4688subject
Has Abstractpub_date
2014-04-22 00:00:00pages
3688issn
2041-1723pii
ncomms4688journal_volume
5pub_type
杂志文章abstract::It has previously been shown that the relative reliability of model-based and model-free reinforcement-learning (RL) systems plays a role in the allocation of behavioral control between them. However, the role of task complexity in the arbitration between these two strategies remains largely unknown. Here, using a com...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13632-1
更新日期:2019-12-16 00:00:00
abstract::AML1-ETO (AE) is a fusion transcription factor, generated by the t(8;21) translocation, that functions as a leukemia promoting oncogene. Here, we demonstrate that TATA-Box Binding Protein Associated Factor 1 (TAF1) associates with K43 acetylated AE and this association plays a pivotal role in the proliferation of AE-e...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12735-z
更新日期:2019-10-29 00:00:00
abstract::Multi-layer structure of functional materials often involves the integration of different crystalline phases. The film growth orientation thus frequently exhibits a transformation, owing to multiple possibilities caused by incompatible in-plane structural symmetry. Nevertheless, the detailed mechanism of the transform...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01655-5
更新日期:2017-11-14 00:00:00
abstract::Compartmentalization of the gut microbiota is thought to be important to system function, but the extent of spatial organization in the gut ecosystem remains poorly understood. Here, we profile the murine colonic microbiota along longitudinal and lateral axes using laser capture microdissection. We found fine-scale sp...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12413-0
更新日期:2019-09-25 00:00:00
abstract::The original version of this Article contained an error in Fig. 2f, in which the phospholipid was incorrectly labelled 'PE' rather than the correct 'PC'. This has now been corrected in the PDF and HTML versions of the Article. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-019-08907-6
更新日期:2019-02-19 00:00:00
abstract::The majority of mammalian genes contain one or more alternative polyadenylation sites. Choice of polyadenylation sites was suggested as one of the underlying mechanisms for generating longer/shorter transcript isoforms. Here, we demonstrate that mature mRNA transcripts can undergo additional cleavage and polyadenylati...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02099-7
更新日期:2017-12-11 00:00:00
abstract::Graphene flakes with giant shape anisotropy are extensively used to establish connectedness electrical percolation in various heterogeneous systems. However, the percolation behaviour of graphene flakes has been recently predicted to be far more complicated than generally anticipated on the basis of excluded volume ar...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9700
更新日期:2015-11-16 00:00:00
abstract::Metagenomic sequencing has greatly improved our ability to profile the composition of environmental and host-associated microbial communities. However, the dependency of most methods on reference genomes, which are currently unavailable for a substantial fraction of microbial species, introduces estimation biases. We ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-08844-4
更新日期:2019-03-04 00:00:00
abstract::Hybrid quantum systems are essential for the realization of distributed quantum networks. In particular, piezo-mechanics operating at typical superconducting qubit frequencies features low thermal excitations, and offers an appealing platform to bridge superconducting quantum processors and optical telecommunication c...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17053-3
更新日期:2020-06-26 00:00:00
abstract::Although it has become increasingly clear that cancers display extensive cellular heterogeneity, the spatial growth dynamics of genetically distinct clones within developing solid tumours remain poorly understood. Here we leverage mosaic analysis with double markers (MADM) to trace subclonal populations retaining or l...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12685
更新日期:2016-09-02 00:00:00
abstract::Bipolaron states, in which two electrons or two holes occupy a single molecule or conjugated polymer segment, are typically considered to be negligible in organic semiconductor devices due to Coulomb repulsion between the two charges. Here we use charge modulation spectroscopy to reveal a bipolaron sheet density >1010...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02459-3
更新日期:2017-12-21 00:00:00
abstract::The atypical chemokine receptor 3 (ACKR3) plays a pivotal role in directing the migration of various cellular populations and its over-expression in tumors promotes cell proliferation and invasiveness. The intracellular signaling pathways transducing ACKR3-dependent effects remain poorly characterized, an issue we add...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18634-y
更新日期:2020-09-25 00:00:00
abstract::Visualization of ion transport in electrolytes provides fundamental understandings of electrolyte dynamics and electrolyte-electrode interactions. However, this is challenging because existing techniques are hard to capture low ionic concentrations and fast electrolyte dynamics. Here we show that stimulated Raman scat...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05289-z
更新日期:2018-07-30 00:00:00
abstract::Mutations in BLM in Bloom Syndrome patients predispose them to multiple types of cancers. Here we report that BLM is recruited in a biphasic manner to annotated DSBs. BLM recruitment is dependent on the presence of NBS1, MRE11 and ATM. While ATM activity is essential for BLM recruitment in early phase, it is dispensab...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03393-8
更新日期:2018-03-09 00:00:00
abstract::Natural systems frequently exploit intricate multiscale and multiphasic structures to achieve functionalities beyond those of man-made systems. Although understanding the chemical make-up of these systems is essential, the passive and active mechanics within biological systems are crucial when considering the many nat...
journal_title:Nature communications
pub_type: 杂志文章,评审
doi:10.1038/ncomms8418
更新日期:2015-07-06 00:00:00
abstract::Colloidal semiconductor nanocrystals have attracted significant interest for applications in solution-processable devices such as light-emitting diodes and solar cells. However, a poor understanding of charge transport in nanocrystal assemblies, specifically the relation between electrical conductance in dark and unde...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1492
更新日期:2011-09-27 00:00:00
abstract::The NLRP3 inflammasome is the most characterized inflammasome activated by cellular infection or stress, which is responsible for the maturation of proinflammatory cytokines IL-1β and IL-18. The precise molecular mechanism for negative regulation of NLRP3 inflammasome activation needs to be further defined. Here we id...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3075
更新日期:2013-01-01 00:00:00
abstract::The flexibility in structural design of organic semiconductors endows organic solar cells (OSCs) not only great function-tunabilities, but also high potential toward practical application. In this work, simple non-fused-ring electron acceptors are developed through two-step synthesis from single aromatic units for con...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-10098-z
更新日期:2019-05-14 00:00:00
abstract::Successive cold winters of severely low temperatures in recent years have had critical social and economic impacts on the mid-latitude continents in the Northern Hemisphere. Although these cold winters are thought to be partly driven by dramatic losses of Arctic sea-ice, the mechanism that links sea-ice loss to cold w...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5646
更新日期:2014-09-02 00:00:00
abstract::For societies with writing systems, hereditary leadership is documented as one of the hallmarks of early political complexity and governance. In contrast, it is unknown whether hereditary succession played a role in the early formation of prehistoric complex societies that lacked writing. Here we use an archaeogenomic...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14115
更新日期:2017-02-21 00:00:00
abstract::Bone tissue, by definition, is an organic-inorganic nanocomposite, where metabolically active cells are embedded within a matrix that is heavily calcified on the nanoscale. Currently, there are no strategies that replicate these definitive characteristics of bone tissue. Here we describe a biomimetic approach where a ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-11455-8
更新日期:2019-08-06 00:00:00
abstract::Despite being highly interdependent, the major biochemical networks of the living cell-the networks of interacting genes and of metabolic reactions, respectively-have been approached mostly as separate systems so far. Recently, a framework for interdependent networks has emerged in the context of statistical physics. ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00587-4
更新日期:2017-09-14 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-020-18712-1
更新日期:2020-09-16 00:00:00
abstract::Making decisions based on choice-outcome history is a crucial, adaptive ability in life. However, the neural circuit mechanisms underlying history-dependent decision-making are poorly understood. In particular, history-related signals have been found in many brain areas during various decision-making tasks, but the ca...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01356-z
更新日期:2017-11-01 00:00:00
abstract::Causal reasoning can shed new light on the major challenges in machine learning for medical imaging: scarcity of high-quality annotated data and mismatch between the development dataset and the target environment. A causal perspective on these issues allows decisions about data collection, annotation, preprocessing, a...
journal_title:Nature communications
pub_type: 杂志文章,评审
doi:10.1038/s41467-020-17478-w
更新日期:2020-07-22 00:00:00
abstract::Understanding the biomolecular interactions between graphene and human immune cells is a prerequisite for its utilization as a diagnostic or therapeutic tool. To characterize the complex interactions between graphene and immune cells, we propose an integrative analytical pipeline encompassing the evaluation of molecul...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01015-3
更新日期:2017-10-24 00:00:00
abstract::Holocene summer temperature reconstructions from northern Europe based on sedimentary pollen records suggest an onset of peak summer warmth around 9,000 years ago. However, pollen-based temperature reconstructions are largely driven by changes in the proportions of tree taxa, and thus the early-Holocene warming signal...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7809
更新日期:2015-04-10 00:00:00
abstract::Choroidal neovascularization (CNV) is a major cause of visual impairment in patients suffering from wet age-related macular degeneration (AMD), particularly when refractory to intraocular anti-VEGF injections. Here we report that treatment with the oral mineralocorticoid receptor (MR) antagonist spironolactone reduces...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-08125-6
更新日期:2019-01-21 00:00:00
abstract::Obesity is a pandemic disease associated with many metabolic alterations and involves several organs and systems. The endocannabinoid system (ECS) appears to be a key regulator of energy homeostasis and metabolism. Here we show that specific deletion of the ECS synthesizing enzyme, NAPE-PLD, in adipocytes induces obes...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7495
更新日期:2015-03-11 00:00:00
abstract::Nanostructured silicon has generated a lot of interest in the past decades as a key material for silicon-based photonics. The low absorption coefficient makes silicon nanocrystals attractive as an active medium in waveguide structures, and their third-order nonlinear optical properties are crucial for the development ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2188
更新日期:2012-01-01 00:00:00