The use of a gas chromatograph coupled to a metal oxide sensor for rapid assessment of stool samples from irritable bowel syndrome and inflammatory bowel disease patients.

abstract：:Oral malodour is a common condition which affects a large proportion of the population, resulting in social, emotional and psychological stress. Certain oral bacteria form a coating called a biofilm on the tongue dorsum and degrade organic compounds releasing volatile sulfur compounds that are malodourous. Current che...

journal_title：Journal of breath research

authors： Rai M,Spratt D,Gomez-Pereira PR,Patel J,Nair SP

更新日期：2016-10-18 00:00:00

abstract：:The forehead was studied as a possible sampling site for capturing changes in volatile organic compound (VOC) profiles associated with psychological-stress. Skin-VOCs were sampled with a polydimethylsilicone (PDMS)-coupon and the resulting VOCs were recovered and analysed with two-stage thermal desorption gas chromato...

journal_title：Journal of breath research

authors： Martin HJ,Turner MA,Bandelow S,Edwards L,Riazanskaia S,Thomas CL

更新日期：2016-11-21 00:00:00

abstract：:The analysis of exhaled breath is drawing a high degree of interest in the diagnostics of various diseases, including lung cancer. Electronic nose (E-nose) technology is one of the perspective approaches in the field due to its relative simplicity and cost efficiency. The use of an E-nose together with pattern recogni...

journal_title：Journal of breath research

authors： Kononov A,Korotetsky B,Jahatspanian I,Gubal A,Vasiliev A,Arsenjev A,Nefedov A,Barchuk A,Gorbunov I,Kozyrev K,Rassadina A,Iakovleva E,Sillanpää M,Safaei Z,Ivanenko N,Stolyarova N,Chuchina V,Ganeev A

更新日期：2019-10-23 00:00:00

abstract：:Cancer cells prefer hyperglycolysis versus oxidative phosphorylation, even in the presence of oxygen. This phenomenon is used through the FDG-PET scans, and may affect the exhaled volatile signature. This study investigates the volatile signature in lung cancer (LC) before and after an oral glucose tolerance test (OGT...

journal_title：Journal of breath research

authors： Feinberg T,Alkoby-Meshulam L,Herbig J,Cancilla JC,Torrecilla JS,Gai Mor N,Bar J,Ilouze M,Haick H,Peled N

更新日期：2016-06-07 00:00:00

abstract：:In this work, we present a hydrophilic self-cleaning condenser surface for the collection of biological and environmental aerosol samples. The condenser is installed in a battery-operated hand-held breath sampling device. The device performance is characterized by the collection and analysis of exhaled breath samples ...

journal_title：Journal of breath research

authors： Zamuruyev KO,Schmidt AJ,Borras E,McCartney MM,Schivo M,Kenyon NJ,Delplanque JP,Davis CE

更新日期：2018-06-08 00:00:00

abstract：:To investigate the premise that levels of endogenous volatile organic compounds (VOC) in breath reflect those in blood, the concentration of acetone and isoprene were measured in radial arterial blood, peripheral venous blood and breath samples from ten healthy volunteers. Coefficients of repeatability as a percentage...

journal_title：Journal of breath research

authors： O'Hara ME,Clutton-Brock TH,Green S,Mayhew CA

更新日期：2009-06-01 00:00:00

abstract：:Bronchiectasis, bronchiolectasis, and bronchiolisation of alveolar regions are salient features of idiopathic pulmonary fibrosis (IPF). We asked whether IPF was associated with physiological changes consistent with increases in the volume of conducting airways, and whether airway volume was related to the severity of ...

journal_title：Journal of breath research

authors： Plantier L,Debray MP,Estellat C,Flamant M,Roy C,Bancal C,Borie R,Israël-Biet D,Mal H,Crestani B,Delclaux C

更新日期：2016-02-01 00:00:00

abstract：:There have been a number of studies in which metal oxide sensors (MOS) have replaced conventional analytical detectors in gas chromatography systems. However, despite the use of these instruments in a range of applications including breath research the sensor responses (i.e. resistance changes w.r.t. concentration of ...

journal_title：Journal of breath research

authors： Gould O,Wieczorek T,de Lacy Costello B,Persad R,Ratcliffe N

更新日期：2017-12-06 00:00:00

abstract：:Tongue coating (TC) mainly consists of protein mostly from exfoliated epithelial cells. Until now, to reduce TC accumulation, only mechanical measures have been available, and the procedure involves unpleasant side effects, such as gagging reflex or carcinogenesis related to mechanical stimulation. We expected that pr...

journal_title：Journal of breath research

authors： Nohno K,Yamaga T,Kaneko N,Miyazaki H

更新日期：2012-03-01 00:00:00

abstract：:Based on the adsorption of analytes in the sampling loop, a time-resolved dynamic dilution introduction method was developed for negative ion mobility spectrometry to continuously monitor end-tidal propofol without other sample pre-separation. The dynamic dilution characteristics of propofol and moisture in the Teflon...

journal_title：Journal of breath research

authors： Zhou Q,Li E,Wang Z,Gong Y,Wang C,Guo L,Li H

更新日期：2015-01-05 00:00:00

abstract：:Arterial lactate concentrations, taken as indicators of physical fitness, in athletes as well as in patients with cardio-respiratory or metabolic diseases, are measured invasively from arterialized ear lobe blood. Currently developed micro enzyme detectors permit a non-invasive measurement of hypoxia-related metabolit...

journal_title：Journal of breath research

authors： Marek EM,Volke J,Hawener I,Platen P,Mückenhoff K,Marek W

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Asthma control does not yet meet the goals of asthma management guidelines. Non-invasive monitoring of airway inflammation may help to improve the level of asthma control in children. OBJECTIVES:(1) To identify a set of exhaled volatile organic compounds (VOCs) that is most predictive for an asthma exacerba...

journal_title：Journal of breath research

authors： van Vliet D,Smolinska A,Jöbsis Q,Rosias P,Muris J,Dallinga J,Dompeling E,van Schooten FJ

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a highly heterogeneous disease and airflow limitation and symptoms only partially capture such heterogeneity. Since COPD is known to affect the production of volatile organic compounds (VOCs), we aimed to verify to which extent exhaled VOCs can characterize new...

journal_title：Journal of breath research

authors： Scarlata S,Finamore P,Santangelo S,Giannunzio G,Pennazza G,Grasso S,Santonico M,Incalzi RA

更新日期：2018-06-08 00:00:00

abstract：:Proton transfer reaction time-of-flight mass spectrometry (PTR-ToF-MS) represents an attractive tool for the real-time analysis of VOC profiles in human breath. Quantification of breath VOCs by means of direct MS may be affected by the matrix, as human breath not only contains several hundred VOCs at the ppbV-pptV lev...

journal_title：Journal of breath research

authors： Trefz P,Schubert JK,Miekisch W

更新日期：2018-03-01 00:00:00

abstract：:Exhaled breath condensate (EBC) is increasingly being used as a non-invasive method for disease diagnosis and environmental exposure assessment. We previously detected the nucleic acids of bacterial pathogens in EBC. Influenza viruses can be transmitted through aerosols during coughing and exhaling. Existing detection...

journal_title：Journal of breath research

authors： Li X,Wang M,Chen J,Lin F,Wang W

更新日期：2021-01-12 00:00:00

abstract：:In this study, the effects of aerobic exercise on the upper airways and their defense mechanisms were investigated in athletes. The athletes ran in two different environments: the downtown streets of the city of São Paulo (Street), more polluted, and an urban forest (Forest), less polluted. Thirty-eight young healthy ...

journal_title：Journal of breath research

authors： Cavalcante de Sá M,Nakagawa NK,Saldiva de André CD,Carvalho-Oliveira R,de Santana Carvalho T,Nicola ML,de André PA,Nascimento Saldiva PH,Vaisberg M

更新日期：2016-12-21 00:00:00

abstract：:Chronic pulmonary infections are the principal cause of morbidity and mortality in individuals with cystic fibrosis (CF). Due to the polymicrobial nature of these infections, the identification of the particular bacterial species responsible is an essential step in diagnosis and treatment. Current diagnostic procedure...

journal_title：Journal of breath research

authors： Nizio KD,Perrault KA,Troobnikoff AN,Ueland M,Shoma S,Iredell JR,Middleton PG,Forbes SL

更新日期：2016-04-27 00:00:00

abstract：:Sugar malabsorption in the bowel can lead to bloating, cramps, diarrhea and other symptoms of irritable bowel syndrome as well as affecting absorption of other nutrients. The hydrogen breath test is now a well established noninvasive test for assessing malabsorption of sugars in the small intestine. However, there are...

journal_title：Journal of breath research

authors： de Lacy Costello BP,Ledochowski M,Ratcliffe NM

更新日期：2013-06-01 00:00:00

abstract：:Breath gas analysis provides insight into human metabolism of healthy and ill individuals. As an innovative and non-invasive method, it opens up options to improve diagnostics, monitoring and treatment decisions. Mid-infrared laser absorption spectroscopy is utilized to detect CH(4), H(2)O, CO(2), NH(3) and CH(3)OH in...

journal_title：Journal of breath research

authors： Hannemann M,Antufjew A,Borgmann K,Hempel F,Ittermann T,Welzel S,Weltmann KD,Völzke H,Röpcke J

更新日期：2011-06-01 00:00:00

abstract：:Selected volatile organic compounds (VOCs) in breath may be considered biomarkers if they are indicative of distinct diseases or disease states. Given the inherent molecular selectivity of vibrational spectroscopy, infrared sensing technologies appear ideally suitable for the determination of endogenous VOCs in breath...

journal_title：Journal of breath research

authors： Perez-Guaita D,Kokoric V,Wilk A,Garrigues S,Mizaikoff B

更新日期：2014-06-01 00:00:00

abstract：:In the current pilot study we aimed to determine whether breath analysis could be used to help recognise intra-abdominal infection, using acute appendicitis as an exemplar condition. Our study included 53 patients (aged 18-88 years) divided into three groups: appendix group, 26 (13 male) patients suffering from acute ...

journal_title：Journal of breath research

authors： Andrews BT,Das P,Denzer W,Ritchie GA,Peverall R,Hamade AM,Hancock G

更新日期：2020-10-22 00:00:00

abstract：:Despite recent progress in Critical Care Medicine, sepsis is still a major medical problem with a high rate of mortality and morbidity especially in intensive care units. Oxidative stress induced by inflammation associated with sepsis causes degradation of heme protein, increases microsomal free heme content, promotes...

journal_title：Journal of breath research

authors： Morimatsu H,Takahashi T,Matsusaki T,Hayashi M,Matsumi J,Shimizu H,Matsumi M,Morita K

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:The analysis of volatile organic compounds (VOCs) in breath allows non-invasive investigations of diseases. Animal studies are conducted as a model to perform research of VOCs and their relation to diseases. In large animal models ruminants were often used as experimental targets. The effect of their physiol...

journal_title：Journal of breath research

authors： Oertel P,Küntzel A,Reinhold P,Köhler H,Schubert JK,Kolb J,Miekisch W

更新日期：2018-05-14 00:00:00

abstract：BACKGROUND:Recent studies have highlighted the possible involvement of leptin in inflammation. The leptin receptor is also expressed by alveolar macrophages, T lymphocytes and bronchial epitelial cells, suggesting a possible role in the cascade of airway inflammation. OBJECTIVES:The aim of the study was to evaluate th...

journal_title：Journal of breath research

authors： Bodini A,Tenero L,Sandri M,Maffeis C,Piazza M,Zanoni L,Peroni D,Boner A,Piacentini G

更新日期：2017-09-27 00:00:00

abstract：:Exhaled breath acetone (BrAce) was investigated during and after submaximal aerobic exercise as a volatile biomarker for metabolic responsiveness in high and lower-fit individuals in a prospective cohort pilot-study. Twenty healthy adults (19-39 years) with different levels of cardiorespiratory fitness (VO2peak), dete...

journal_title：Journal of breath research

authors： Königstein K,Abegg S,Schorn AN,Weber IC,Derron N,Krebs A,Gerber PA,Schmidt-Trucksäss A,Güntner AT

更新日期：2020-10-31 00:00:00

abstract：:Due to its high sensitivity, compact size and low cost ion mobility spectrometry (IMS) has the potential to become a point-of-care breath analyzer. Therefore, we developed a prototype of a compact, closed gas loop IMS with gas chromatographic (GC) pre-separation and high resolving power of R  =  90. In this study, we ...

journal_title：Journal of breath research

authors： Allers M,Langejuergen J,Gaida A,Holz O,Schuchardt S,Hohlfeld JM,Zimmermann S

更新日期：2016-04-08 00:00:00

abstract：:The data obtained for the concentration distributions of the most abundant volatile metabolites in exhaled breath determined in two independent studies are reviewed, the first limited study involving five healthy volunteers providing daily breath samples over a month, and the subsequent study involving 30 healthy volu...

journal_title：Journal of breath research

authors： Smith D,Turner C,Spaněl P

更新日期：2007-09-01 00:00:00

abstract：:Breath contains hundreds of volatile organic compounds (VOCs), the composition of which is altered in a wide variety of diseases. Bacteria are implicated in the formation of VOCs, but the biochemical mechanisms that lead to the formation of breath VOCs remain largely hypothetical. We hypothesized that bacterial DNA fr...

journal_title：Journal of breath research

authors： Bos LD,Meinardi S,Blake D,Whiteson K

更新日期：2016-12-17 00:00:00

abstract：:Poor compliance to prescribed medication regimens in clinical trials continues to be a major obstacle to drug development success and cost reduction, and there is no gold standard technology that is cheap and effective to reliably measure drug compliance. This paper presents a new drug compliance scheme based on the d...

journal_title：Journal of breath research

authors： Meka VV,Lutz BJ,Melker RJ,Euliano NR

更新日期：2007-12-01 00:00:00

abstract：:The analysis of volatile organic compounds (VOCs) by an electronic nose (e-nose) is a groundbreaking method that provides distinct exhaled molecular patterns in several respiratory and systemic diseases. It has been shown that an e-nose can detect obstructive sleep apnea (OSA) as well as chronic obstructive pulmonary ...

journal_title：Journal of breath research

authors： Dragonieri S,Quaranta VN,Carratu P,Ranieri T,Resta O

更新日期：2016-11-03 00:00:00