Cluster analysis on breath print of newly diagnosed COPD patients: effects of therapy.

abstract：:Exhaled breath collection is used to identify and monitor inflammatory or oxidative components in breath. Exhaled breath sample collection is noninvasive and would greatly benefit human pollutant exposure research. We demonstrate the efficacy of exhaled breath collection and analysis in two human exposure studies to o...

journal_title：Journal of breath research

authors： Sawyer K,Samet JM,Ghio AJ,Pleil JD,Madden MC

更新日期：2008-09-01 00:00:00

abstract：:The objective of this study is to evaluate tonsil odor as a contributor to halitosis and to study the reduction of oral malodor by mouth rinsing, without tonsil treatment. In 48 halitosis patients, tonsil odor and oral malodor were assessed through the 0-5 scale. In tonsil odor assessment, a dental burnisher was inser...

journal_title：Journal of breath research

authors： Talebian A,Tazhibi M,Iranpoor R,Semyari H,Taherzadeh M

更新日期：2008-03-01 00:00:00

abstract：:Arterial lactate concentrations, taken as indicators of physical fitness, in athletes as well as in patients with cardio-respiratory or metabolic diseases, are measured invasively from arterialized ear lobe blood. Currently developed micro enzyme detectors permit a non-invasive measurement of hypoxia-related metabolit...

journal_title：Journal of breath research

authors： Marek EM,Volke J,Hawener I,Platen P,Mückenhoff K,Marek W

更新日期：2010-03-01 00:00:00

abstract：:A point-of-care, non-invasive, low-cost and sensitive nano-biodiagnostic is needed in today's age for rapid and accurate self-diagnosis as well as for the management of asthma, which is advantageous for low resource areas where asthma is prevalent. The objective of this research work was to prepare the miniature, nano...

journal_title：Journal of breath research

authors： Shende P,Vaidya J,Kulkarni YA

更新日期：2019-06-25 00:00:00

abstract：:Due to its high sensitivity, compact size and low cost ion mobility spectrometry (IMS) has the potential to become a point-of-care breath analyzer. Therefore, we developed a prototype of a compact, closed gas loop IMS with gas chromatographic (GC) pre-separation and high resolving power of R  =  90. In this study, we ...

journal_title：Journal of breath research

authors： Allers M,Langejuergen J,Gaida A,Holz O,Schuchardt S,Hohlfeld JM,Zimmermann S

更新日期：2016-04-08 00:00:00

abstract：:Breath contains hundreds of volatile organic compounds (VOCs), the composition of which is altered in a wide variety of diseases. Bacteria are implicated in the formation of VOCs, but the biochemical mechanisms that lead to the formation of breath VOCs remain largely hypothetical. We hypothesized that bacterial DNA fr...

journal_title：Journal of breath research

authors： Bos LD,Meinardi S,Blake D,Whiteson K

更新日期：2016-12-17 00:00:00

abstract：:Wheeze is a common symptom in preschool children. The role of bacteria, regulatory T (T(reg)) cells and their association with airway inflammation in preschool wheeze is largely unknown. We evaluated inflammatory markers in exhaled breath condensate (EBC), bacterial colonization and circulating T(reg) cells in prescho...

journal_title：Journal of breath research

authors： van de Kant KD,Klaassen EM,van Aerde KJ,Damoiseaux J,Bruggeman CA,Stelma FF,Stobberingh EE,Muris JW,Jöbsis Q,van Schayck OC,Dompeling E

更新日期：2012-12-01 00:00:00

abstract：:Poor compliance to prescribed medication regimens in clinical trials continues to be a major obstacle to drug development success and cost reduction, and there is no gold standard technology that is cheap and effective to reliably measure drug compliance. This paper presents a new drug compliance scheme based on the d...

journal_title：Journal of breath research

authors： Meka VV,Lutz BJ,Melker RJ,Euliano NR

更新日期：2007-12-01 00:00:00

abstract：:Breath tests have been used to investigate many physiological functions. Recently, we have developed a breath test system by using a non-invasive technique in conscious rats. In this study, we investigated the effect of atropine sulfate on the gastric emptying and gastrocecal transit time using [1-(13)C]acetic acid an...

journal_title：Journal of breath research

authors： Uchida M,Yoshida K,Shimizu K

更新日期：2009-12-01 00:00:00

abstract：:Exhaled NO (FE(NO)) measurements have been utilized as a marker to diagnose asthma as well as a non-invasive tool for monitoring airway inflammation and the response to anti-inflammatory medications. One area where this non-invasive monitoring may be helpful is for asthmatic athletes as they train for competitive even...

journal_title：Journal of breath research

authors： Grob NM,Laskowski D,Dweik RA

更新日期：2008-09-01 00:00:00

abstract：:Fractional exhaled NO (FeNO) is universally considered an indirect marker of eosinophilic airways inflammation, playing an important role in the physiopathology of childhood asthma. Advances in technology and standardization have allowed a wider use of FeNO in clinical practice in children from the age of four years. ...

journal_title：Journal of breath research

authors： Piacentini GL,Cattazzo E,Tezza G,Peroni DG

更新日期：2012-06-01 00:00:00

abstract：:Despite recent progress in Critical Care Medicine, sepsis is still a major medical problem with a high rate of mortality and morbidity especially in intensive care units. Oxidative stress induced by inflammation associated with sepsis causes degradation of heme protein, increases microsomal free heme content, promotes...

journal_title：Journal of breath research

authors： Morimatsu H,Takahashi T,Matsusaki T,Hayashi M,Matsumi J,Shimizu H,Matsumi M,Morita K

更新日期：2010-12-01 00:00:00

abstract：:Analysis of breath acetone could be useful in the Intensive Care Unit (ICU) setting to monitor evidence of starvation and metabolic stress. The aims of this study were to examine the relationship between acetone concentrations in breath and blood in critical illness, to explore any changes in breath acetone concentrat...

journal_title：Journal of breath research

authors： Sturney SC,Storer MK,Shaw GM,Shaw DE,Epton MJ

更新日期：2013-09-01 00:00:00

abstract：:In this study, the effects of aerobic exercise on the upper airways and their defense mechanisms were investigated in athletes. The athletes ran in two different environments: the downtown streets of the city of São Paulo (Street), more polluted, and an urban forest (Forest), less polluted. Thirty-eight young healthy ...

journal_title：Journal of breath research

authors： Cavalcante de Sá M,Nakagawa NK,Saldiva de André CD,Carvalho-Oliveira R,de Santana Carvalho T,Nicola ML,de André PA,Nascimento Saldiva PH,Vaisberg M

更新日期：2016-12-21 00:00:00

abstract：:Exhaled breath acetone (BrAce) was investigated during and after submaximal aerobic exercise as a volatile biomarker for metabolic responsiveness in high and lower-fit individuals in a prospective cohort pilot-study. Twenty healthy adults (19-39 years) with different levels of cardiorespiratory fitness (VO2peak), dete...

journal_title：Journal of breath research

authors： Königstein K,Abegg S,Schorn AN,Weber IC,Derron N,Krebs A,Gerber PA,Schmidt-Trucksäss A,Güntner AT

更新日期：2020-10-31 00:00:00

abstract：:The haloamines, including the chloramines (H(2)NCl, HNCl(2)) and bromamine (H(2)NBr), are diffusible gases that are likely to be produced during inflammation and so may be present as markers of lung inflammation on breath. Although haloamines are quite reactive, it is possible to measure these compounds in humid sampl...

journal_title：Journal of breath research

authors： Storer MK,Dummer JD,Cook J,McEwan M,Epton MJ

更新日期：2011-09-01 00:00:00

abstract：:Concentrations of exhaled volatile organic compounds (VOCs) may depend not only on biochemical or pathologic processes but also on physiological parameters. As breath sampling may be done in different body positions, effects of the sampling position on exhaled VOC concentrations were investigated by means of real-time...

journal_title：Journal of breath research

authors： Sukul P,Trefz P,Kamysek S,Schubert JK,Miekisch W

更新日期：2015-11-19 00:00:00

abstract：:Profiling the body chemistry by means of volatile organic compounds (VOCs) in the breath opens exciting new avenues in medical diagnostics. Gas sensors could provide ideal platforms for realizing portable, hand-held breath testing devices in the near future. This review summarizes the latest developments and applicati...

journal_title：Journal of breath research

authors： Tisch U,Haick H

更新日期：2014-06-01 00:00:00

abstract：:Biogenic amines are interesting compounds which may be of use for medical diagnosis or therapeutic monitoring. The present paper deals with the problems that occur with concentration determination of dimethylamine (DMA) and trimethylamine (TMA). These occur in the breath of people suffering from renal disease. The mea...

journal_title：Journal of breath research

authors： Wzorek B,Mochalski P,Sliwka I,Amann A

更新日期：2010-06-01 00:00:00

abstract：:The data obtained for the concentration distributions of the most abundant volatile metabolites in exhaled breath determined in two independent studies are reviewed, the first limited study involving five healthy volunteers providing daily breath samples over a month, and the subsequent study involving 30 healthy volu...

journal_title：Journal of breath research

authors： Smith D,Turner C,Spaněl P

更新日期：2007-09-01 00:00:00

abstract：:Based on the adsorption of analytes in the sampling loop, a time-resolved dynamic dilution introduction method was developed for negative ion mobility spectrometry to continuously monitor end-tidal propofol without other sample pre-separation. The dynamic dilution characteristics of propofol and moisture in the Teflon...

journal_title：Journal of breath research

authors： Zhou Q,Li E,Wang Z,Gong Y,Wang C,Guo L,Li H

更新日期：2015-01-05 00:00:00

abstract：:There is much clinical interest in the development of a low-cost and reliable test for diagnosing inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), two very distinct diseases that can present with similar symptoms. The assessment of stool samples for the diagnosis of gastro-intestinal diseases is in...

journal_title：Journal of breath research

authors： Shepherd SF,McGuire ND,de Lacy Costello BP,Ewen RJ,Jayasena DH,Vaughan K,Ahmed I,Probert CS,Ratcliffe NM

更新日期：2014-06-01 00:00:00

abstract：:While there has been progress in making use of breath tests to guide clinical decision making, the full potential of exhaled breath analysis still remains to be exploited. Here we summarize some of the reasons why this is the case, what we have done so far to overcome some of the existing obstacles, and our vision of ...

journal_title：Journal of breath research

authors： Singh KD,Del Miguel GV,Gaugg MT,Ibañez AJ,Zenobi R,Kohler M,Frey U,Sinues PM

更新日期：2018-02-07 00:00:00

abstract：:Selected volatile organic compounds (VOCs) in breath may be considered biomarkers if they are indicative of distinct diseases or disease states. Given the inherent molecular selectivity of vibrational spectroscopy, infrared sensing technologies appear ideally suitable for the determination of endogenous VOCs in breath...

journal_title：Journal of breath research

authors： Perez-Guaita D,Kokoric V,Wilk A,Garrigues S,Mizaikoff B

更新日期：2014-06-01 00:00:00

abstract：:In this article, a database of blood:air and fat:air partition coefficients (λ b:a and λ f:a) is reported for estimating 1678 volatile organic compounds recently reported to appear in the volatilome of the healthy human. For this purpose, a quantitative structure-property relationship (QSPR) approach was applied and a...

journal_title：Journal of breath research

authors： Kramer C,Mochalski P,Unterkofler K,Agapiou A,Ruzsanyi V,Liedl KR

更新日期：2016-01-27 00:00:00

abstract：BACKGROUND:Asthma control does not yet meet the goals of asthma management guidelines. Non-invasive monitoring of airway inflammation may help to improve the level of asthma control in children. OBJECTIVES:(1) To identify a set of exhaled volatile organic compounds (VOCs) that is most predictive for an asthma exacerba...

journal_title：Journal of breath research

authors： van Vliet D,Smolinska A,Jöbsis Q,Rosias P,Muris J,Dallinga J,Dompeling E,van Schooten FJ

更新日期：2017-03-01 00:00:00

abstract：:The lung just like all other organs is affected by age. The lung matures by the age of 20 and age-related changes start around middle age, at 40-50 years. Exhaled nitric oxide (FENO) has been shown to be age, height and gender dependent. We hypothesize that the nitric oxide (NO) parameters alveolar NO (CANO), airway f...

journal_title：Journal of breath research

authors： Högman M,Thornadtsson A,Liv P,Hua-Huy T,Dinh-Xuan AT,Tufvesson E,Dressel H,Janson C,Koskela K,Oksa P,Sauni R,Uitti J,Moilanen E,Lehtimäki L

更新日期：2017-09-13 00:00:00

abstract：BACKGROUND:Recent studies have highlighted the possible involvement of leptin in inflammation. The leptin receptor is also expressed by alveolar macrophages, T lymphocytes and bronchial epitelial cells, suggesting a possible role in the cascade of airway inflammation. OBJECTIVES:The aim of the study was to evaluate th...

journal_title：Journal of breath research

authors： Bodini A,Tenero L,Sandri M,Maffeis C,Piazza M,Zanoni L,Peroni D,Boner A,Piacentini G

更新日期：2017-09-27 00:00:00

abstract：BACKGROUND:The analysis of volatile organic compounds (VOCs) in breath allows non-invasive investigations of diseases. Animal studies are conducted as a model to perform research of VOCs and their relation to diseases. In large animal models ruminants were often used as experimental targets. The effect of their physiol...

journal_title：Journal of breath research

authors： Oertel P,Küntzel A,Reinhold P,Köhler H,Schubert JK,Kolb J,Miekisch W

更新日期：2018-05-14 00:00:00

abstract：:The design, realization and testing of a CO(2)-triggered breath sampler, capable of a separate collection of dead space and end-tidal air on multiple breaths, is presented. This sampling procedure has advantages in terms of the sample volume, insights regarding the origin of compounds, increased reproducibility and hi...

journal_title：Journal of breath research

authors： Di Francesco F,Loccioni C,Fioravanti M,Russo A,Pioggia G,Ferro M,Roehrer I,Tabucchi S,Onor M

更新日期：2008-09-01 00:00:00