Abstract:
:In this study, the effects of aerobic exercise on the upper airways and their defense mechanisms were investigated in athletes. The athletes ran in two different environments: the downtown streets of the city of São Paulo (Street), more polluted, and an urban forest (Forest), less polluted. Thirty-eight young healthy athletes ran for 45 min d-1 randomly during five consecutive days, with an interval of 48 h before changing environment. Clinical parameters and respiratory tract defense markers were evaluated before and after the first run on Mondays (1 d) and on Fridays (5 d). Street presented higher mean PM2.5 concentrations (65.1 ± 39.1 µg m-3, p < 0.001) and lower temperature (22.0 °C, p = 0.010) than Forest (22.6 ± 15.3 µg m-3 and 22.8 °C). After 1 d Street running, subjects showed an increment in heart rate (p < 0.001). At day 5, there was twice the number of athletes with impaired nasal mucociliary clearance (MCC) in the Street runners group when compared to the Forest runners group. Exhaled breath condensate pH values increased in the Forest group, with significant differences between groups in day 1 (p = 0.006) and day 5 (p < 0.001), despite the fact that both groups showed values within the normal range. After exposure to both environments, the number of cells in the nasal lavage fluid was reduced after exercise (p = 0.014), without alterations in cell type and IL-8 and IL-10 concentrations. Aerobic exercise can either maintain or acutely enhance MCC and it may help to regulate inflammatory responses in the airways. Here we show that exercise practice in polluted outdoor environment, over a 5 d period, impairs MCC. In contrast, athletes running in the less polluted environment (Forest) show higher exhaled breath condensate pH values when compared to those who exercised in a more polluted environment (Street).
journal_name
J Breath Resjournal_title
Journal of breath researchauthors
Cavalcante de Sá M,Nakagawa NK,Saldiva de André CD,Carvalho-Oliveira R,de Santana Carvalho T,Nicola ML,de André PA,Nascimento Saldiva PH,Vaisberg Mdoi
10.1088/1752-7163/10/4/046018subject
Has Abstractpub_date
2016-12-21 00:00:00pages
046018issue
4eissn
1752-7155issn
1752-7163journal_volume
10pub_type
杂志文章,随机对照试验abstract::The sensitivity of selected ion flow tube mass spectrometry, SIFT-MS, has been increased such that it is now possible to detect metabolites present at a part-per-billion, ppb, level in single breath exhalations. However, to utilize this improved sensitivity, the overlaps (coincidences) of those ions resulting from int...
journal_title:Journal of breath research
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journal_title:Journal of breath research
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abstract::Profiling the body chemistry by means of volatile organic compounds (VOCs) in the breath opens exciting new avenues in medical diagnostics. Gas sensors could provide ideal platforms for realizing portable, hand-held breath testing devices in the near future. This review summarizes the latest developments and applicati...
journal_title:Journal of breath research
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journal_title:Journal of breath research
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journal_title:Journal of breath research
pub_type: 杂志文章
doi:10.1088/1752-7155/7/4/046002
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journal_title:Journal of breath research
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journal_title:Journal of breath research
pub_type: 杂志文章
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journal_title:Journal of breath research
pub_type: 杂志文章
doi:10.1088/1752-7163/aba816
更新日期:2020-10-24 00:00:00
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journal_title:Journal of breath research
pub_type: 杂志文章
doi:10.1088/1752-7155/6/2/026002
更新日期:2012-06-01 00:00:00
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journal_title:Journal of breath research
pub_type: 杂志文章
doi:10.1088/1752-7155/3/2/027005
更新日期:2009-06-01 00:00:00
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journal_title:Journal of breath research
pub_type: 杂志文章
doi:10.1088/1752-7163/abd14c
更新日期:2021-01-12 00:00:00
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journal_title:Journal of breath research
pub_type: 杂志文章
doi:10.1088/1752-7163/abba88
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journal_title:Journal of breath research
pub_type: 杂志文章
doi:10.1088/1752-7163/aa9eea
更新日期:2018-03-01 00:00:00
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journal_title:Journal of breath research
pub_type: 杂志文章
doi:10.1088/1752-7163/aa7957
更新日期:2017-09-13 00:00:00
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journal_title:Journal of breath research
pub_type: 杂志文章
doi:10.1088/1752-7155/1/2/026006
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journal_title:Journal of breath research
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journal_title:Journal of breath research
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journal_title:Journal of breath research
pub_type: 杂志文章
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journal_title:Journal of breath research
pub_type: 杂志文章,多中心研究
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journal_title:Journal of breath research
pub_type: 杂志文章
doi:10.1088/1752-7155/6/4/046001
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