Exhaled breath condensate for lung cancer protein analysis: a review of methods and biomarkers.

abstract：:Reactive oxygen species are associated with tissue inflammation and injury. Our laboratory has demonstrated that ethane, a stable product of lipid peroxidation, in exhaled breath can be used to measure total body oxidative stress. Herein patients were studied who underwent outpatient surgery, laproscopic bilateral tub...

journal_title：Journal of breath research

authors： Brown RH,Risby TH

更新日期：2009-03-01 00:00:00

abstract：:Volatile organic compounds (VOCs) in exhaled human breath can serve as potential disease-specific and exposure biomarkers and therefore can reveal information about a subject's health and environment. Pyridine, a VOC marker for exposure to tobacco smoke, and isoprene, a liver disease biomarker, were studied using atmo...

journal_title：Journal of breath research

authors： Kapishon V,Koyanagi GK,Blagojevic V,Bohme DK

更新日期：2013-06-01 00:00:00

abstract：:Robust methods for breath sampling and analysis are required for potential clinical applications. We have evaluated an improved sampling and experimental design, assessing instrumental and biological variability within and across breath measurements. Calibration curves for selected relevant volatile organic compounds...

journal_title：Journal of breath research

authors： Basanta M,Ibrahim B,Douce D,Morris M,Woodcock A,Fowler SJ

更新日期：2012-06-01 00:00:00

abstract：:Selected volatile organic compounds (VOCs) in breath may be considered biomarkers if they are indicative of distinct diseases or disease states. Given the inherent molecular selectivity of vibrational spectroscopy, infrared sensing technologies appear ideally suitable for the determination of endogenous VOCs in breath...

journal_title：Journal of breath research

authors： Perez-Guaita D,Kokoric V,Wilk A,Garrigues S,Mizaikoff B

更新日期：2014-06-01 00:00:00

abstract：:Leptin plays a key role in obstructive sleep apnea syndrome (OSAS). Leptin production in human airways has been previously evaluated by measuring leptin concentration in the exhaled breath condensate and in the induced sputum. The aim was to study leptin expression in the cells of induced sputum and in exhaled breath ...

journal_title：Journal of breath research

authors： Carpagnano GE,Resta O,Pergola GD,Sabato R,Foschino Barbaro MP

更新日期：2010-09-01 00:00:00

abstract：:Since the ancient discovery of the 'sweet odor' in human breath gas, pursuits of the breath analysis-based disease diagnostics have never stopped. Actually, the 'smell' of the breath, as one of three key disease diagnostic techniques, has been used in Eastern-Medicine for more than three thousand years. With advanceme...

journal_title：Journal of breath research

authors： Wang Z,Wang C

更新日期：2013-09-01 00:00:00

abstract：:In this study, the effects of aerobic exercise on the upper airways and their defense mechanisms were investigated in athletes. The athletes ran in two different environments: the downtown streets of the city of São Paulo (Street), more polluted, and an urban forest (Forest), less polluted. Thirty-eight young healthy ...

journal_title：Journal of breath research

authors： Cavalcante de Sá M,Nakagawa NK,Saldiva de André CD,Carvalho-Oliveira R,de Santana Carvalho T,Nicola ML,de André PA,Nascimento Saldiva PH,Vaisberg M

更新日期：2016-12-21 00:00:00

abstract：:Radiation dose is important in radiotherapy. Too little, and the treatment is not effective, too much causes radiation toxicity. A biochemical measurement of the effect of radiotherapy would be useful in personalisation of this treatment. This study evaluated changes in exhaled breath volatile organic compounds (VOC) ...

journal_title：Journal of breath research

authors： Salman D,Eddleston M,Darnley K,Nailon WH,McLaren DB,Hadjithelki A,Ruszkiewicz D,Langejuergen J,Alkhalifa Y,Phillips I,Thomas CLP

更新日期：2020-10-24 00:00:00

abstract：:Tongue coating (TC) mainly consists of protein mostly from exfoliated epithelial cells. Until now, to reduce TC accumulation, only mechanical measures have been available, and the procedure involves unpleasant side effects, such as gagging reflex or carcinogenesis related to mechanical stimulation. We expected that pr...

journal_title：Journal of breath research

authors： Nohno K,Yamaga T,Kaneko N,Miyazaki H

更新日期：2012-03-01 00:00:00

abstract：:The data obtained for the concentration distributions of the most abundant volatile metabolites in exhaled breath determined in two independent studies are reviewed, the first limited study involving five healthy volunteers providing daily breath samples over a month, and the subsequent study involving 30 healthy volu...

journal_title：Journal of breath research

authors： Smith D,Turner C,Spaněl P

更新日期：2007-09-01 00:00:00

abstract：:This study aimed to analyze the impact of chewing gum on halitosis parameters. Three databases were searched with the following focused question: 'Can chewing gum additionally reduce halitosis parameters, such as organoleptic scores and volatile sulfur compounds (VSC), when compared to a control treatment'? Controlled...

journal_title：Journal of breath research

authors： Muniz FW,Friedrich SA,Silveira CF,Rösing CK

更新日期：2017-02-17 00:00:00

abstract：:In this article, a database of blood:air and fat:air partition coefficients (λ b:a and λ f:a) is reported for estimating 1678 volatile organic compounds recently reported to appear in the volatilome of the healthy human. For this purpose, a quantitative structure-property relationship (QSPR) approach was applied and a...

journal_title：Journal of breath research

authors： Kramer C,Mochalski P,Unterkofler K,Agapiou A,Ruzsanyi V,Liedl KR

更新日期：2016-01-27 00:00:00

abstract：:Exhaled breath collection is used to identify and monitor inflammatory or oxidative components in breath. Exhaled breath sample collection is noninvasive and would greatly benefit human pollutant exposure research. We demonstrate the efficacy of exhaled breath collection and analysis in two human exposure studies to o...

journal_title：Journal of breath research

authors： Sawyer K,Samet JM,Ghio AJ,Pleil JD,Madden MC

更新日期：2008-09-01 00:00:00

abstract：:Breath gas analysis provides insight into human metabolism of healthy and ill individuals. As an innovative and non-invasive method, it opens up options to improve diagnostics, monitoring and treatment decisions. Mid-infrared laser absorption spectroscopy is utilized to detect CH(4), H(2)O, CO(2), NH(3) and CH(3)OH in...

journal_title：Journal of breath research

authors： Hannemann M,Antufjew A,Borgmann K,Hempel F,Ittermann T,Welzel S,Weltmann KD,Völzke H,Röpcke J

更新日期：2011-06-01 00:00:00

abstract：:Rodent and nonhuman primate studies indicate that developmental programming by reduced perinatal nutrition negatively impacts life course cardio-metabolic health. We have developed a baboon model in which we feed control mothers (CON) ad libitum while nutrient restricted mothers are fed 70% of ad libitum global feed i...

journal_title：Journal of breath research

authors： Bishop AC,Libardoni M,Choudary A,Misra B,Lange K,Bernal J,Nijland M,Li C,Olivier M,Nathanielsz PW,Cox LA

更新日期：2018-05-14 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD)/emphysema risk groups are well defined and screening allows for early identification of disease. The capability of exhaled volatile organic compounds (VOCs) to detect emphysema, as found by computed tomography (CT) in current and former heavy smokers participating in a lung...

journal_title：Journal of breath research

authors： Cristescu SM,Gietema HA,Blanchet L,Kruitwagen CL,Munnik P,van Klaveren RJ,Lammers JW,Buydens L,Harren FJ,Zanen P

更新日期：2011-12-01 00:00:00

abstract：:In this work, we present a hydrophilic self-cleaning condenser surface for the collection of biological and environmental aerosol samples. The condenser is installed in a battery-operated hand-held breath sampling device. The device performance is characterized by the collection and analysis of exhaled breath samples ...

journal_title：Journal of breath research

authors： Zamuruyev KO,Schmidt AJ,Borras E,McCartney MM,Schivo M,Kenyon NJ,Delplanque JP,Davis CE

更新日期：2018-06-08 00:00:00

abstract：:Exhaled nitric oxide (eNO) has been suggested to be a marker of small airway injury. We investigated the effects of different ventilation strategies on eNO. Sixty-nine patients who received elective open abdominal surgery under general anesthesia with more than 2 h of surgery duration were randomly divided into three ...

journal_title：Journal of breath research

authors： Cui Y,Pi X,Wang C,Liu S,Gong Y,Wang Y,Zhang F,Shi J,Lin Z,Zhang X,Li E

更新日期：2015-02-26 00:00:00

abstract：:Aircraft engine exhaust increases the number concentration of nanoparticles (NP) in the surrounding environment. Health concerns related to NP raise the question of the exposure and health monitoring of airport workers. No biological monitoring study on this profession has been reported to date. The aim was to evaluat...

journal_title：Journal of breath research

authors： Marie-Desvergne C,Dubosson M,Touri L,Zimmermann E,Gaude-Môme M,Leclerc L,Durand C,Klerlein M,Molinari N,Vachier I,Chanez P,Mossuz VC

更新日期：2016-07-13 00:00:00

abstract：:Exhaled NO (FE(NO)) measurements have been utilized as a marker to diagnose asthma as well as a non-invasive tool for monitoring airway inflammation and the response to anti-inflammatory medications. One area where this non-invasive monitoring may be helpful is for asthmatic athletes as they train for competitive even...

journal_title：Journal of breath research

authors： Grob NM,Laskowski D,Dweik RA

更新日期：2008-09-01 00:00:00

abstract：:Breath analysis techniques offer a potential revolution in health care diagnostics, especially if these techniques can be brought into standard use in the clinic and at home. The advent of microsensors combined with smart sensor system technology enables a new generation of sensor systems with significantly enhanced c...

journal_title：Journal of breath research

authors： Hunter GW,Xu JC,Biaggi-Labiosa AM,Laskowski D,Dutta PK,Mondal SP,Ward BJ,Makel DB,Liu CC,Chang CW,Dweik RA

更新日期：2011-09-01 00:00:00

abstract：:There are many respiratory infections such as influenza that cause epidemics. These respiratory infection epidemics can be effectively prevented by determining the presence or absence of infections in patients using frequent tests. We think that self-diagnosis may be possible using a system that can collect and detect...

journal_title：Journal of breath research

authors： Takenaka K,Togashi S,Miyake R,Sakaguchi T,Hide M

更新日期：2016-07-22 00:00:00

abstract：:To investigate the premise that levels of endogenous volatile organic compounds (VOC) in breath reflect those in blood, the concentration of acetone and isoprene were measured in radial arterial blood, peripheral venous blood and breath samples from ten healthy volunteers. Coefficients of repeatability as a percentage...

journal_title：Journal of breath research

authors： O'Hara ME,Clutton-Brock TH,Green S,Mayhew CA

更新日期：2009-06-01 00:00:00

abstract：:Breath analysis represents a new frontier in medical diagnosis and a powerful tool for cancer biomarker discovery due to the recent development of analytical platforms for the detection and identification of human exhaled volatile compounds. Statistical and bioinformatic tools may represent an effective complement to ...

journal_title：Journal of breath research

authors： Martinez-Lozano Sinues P,Landoni E,Miceli R,Dibari VF,Dugo M,Agresti R,Tagliabue E,Cristoni S,Orlandi R

更新日期：2015-09-21 00:00:00

abstract：:The current diagnostic challenge with diagnosing hepatic encephalopathy (HE) is identifying those with minimal HE as opposed to the more clinically apparent covert/overt HE. Rifaximin, is an effective therapy but earlier identification and treatment of HE could prevent liver disease progression and hospitalization. Ou...

journal_title：Journal of breath research

authors： Arasaradnam RP,McFarlane M,Ling K,Wurie S,O'Connell N,Nwokolo CU,Bardhan KD,Skinner J,Savage RS,Covington JA

更新日期：2016-02-11 00:00:00

abstract：:A point-of-care, non-invasive, low-cost and sensitive nano-biodiagnostic is needed in today's age for rapid and accurate self-diagnosis as well as for the management of asthma, which is advantageous for low resource areas where asthma is prevalent. The objective of this research work was to prepare the miniature, nano...

journal_title：Journal of breath research

authors： Shende P,Vaidya J,Kulkarni YA

更新日期：2019-06-25 00:00:00

abstract：:Sugar malabsorption in the bowel can lead to bloating, cramps, diarrhea and other symptoms of irritable bowel syndrome as well as affecting absorption of other nutrients. The hydrogen breath test is now a well established noninvasive test for assessing malabsorption of sugars in the small intestine. However, there are...

journal_title：Journal of breath research

authors： de Lacy Costello BP,Ledochowski M,Ratcliffe NM

更新日期：2013-06-01 00:00:00

abstract：:Blood ammonia is routinely used in clinical settings to assess systemic ammonia in hepatic encephalopathy and urea cycle disorders. Despite its drawbacks, blood measurement is often used as a comparator in breath studies because it is a standard clinical test. We sought to evaluate sources of measurement error and pot...

journal_title：Journal of breath research

authors： Spacek LA,Mudalel M,Tittel F,Risby TH,Solga SF

更新日期：2015-12-14 00:00:00

abstract：:There is much clinical interest in the development of a low-cost and reliable test for diagnosing inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), two very distinct diseases that can present with similar symptoms. The assessment of stool samples for the diagnosis of gastro-intestinal diseases is in...

journal_title：Journal of breath research

authors： Shepherd SF,McGuire ND,de Lacy Costello BP,Ewen RJ,Jayasena DH,Vaughan K,Ahmed I,Probert CS,Ratcliffe NM

更新日期：2014-06-01 00:00:00

abstract：:The analysis of exhaled breath is drawing a high degree of interest in the diagnostics of various diseases, including lung cancer. Electronic nose (E-nose) technology is one of the perspective approaches in the field due to its relative simplicity and cost efficiency. The use of an E-nose together with pattern recogni...

journal_title：Journal of breath research

authors： Kononov A,Korotetsky B,Jahatspanian I,Gubal A,Vasiliev A,Arsenjev A,Nefedov A,Barchuk A,Gorbunov I,Kozyrev K,Rassadina A,Iakovleva E,Sillanpää M,Safaei Z,Ivanenko N,Stolyarova N,Chuchina V,Ganeev A

更新日期：2019-10-23 00:00:00