Abstract:
:The exceptional interest in improving the limitations of data storage, molecular electronics and optoelectronics has promoted the development of an ever increasing number of techniques used to pattern polymers at micro and nanoscale. Most of them rely on atomic force microscopy to thermally or electrostatically induce mass transport, thereby creating topographic features. Here we show that the mechanical interaction between the tip of the atomic force microscope and the surface of π-conjugated polymeric films produces a local increase of molecular disorder, inducing a localized lowering of the semiconductor conductivity, not associated to detectable modifications in the surface topography. This phenomenon allows for the swift production of low-conductivity patterns on the film surface at a speed exceeding 20 μm s⁻¹; paths have a resolution in the order of the tip size (20 nm) and are detected by a conducting-atomic force microscopy tip in the conductivity maps.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Farina M,Ye T,Lanzani G,di Donato A,Venanzoni G,Mencarelli D,Pietrangelo T,Morini A,Keivanidis PEdoi
10.1038/ncomms3668subject
Has Abstractpub_date
2013-01-01 00:00:00pages
2668issn
2041-1723pii
ncomms3668journal_volume
4pub_type
杂志文章abstract::The striking diversity of bird beak shapes is an outcome of natural selection, yet the relative importance of the limitations imposed by the process of beak development on generating such variation is unclear. Untangling these factors requires mapping developmental mechanisms over a phylogeny far exceeding model syste...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4700
更新日期:2014-04-16 00:00:00
abstract::RNA has emerged as a promising material for nanostructure and microstructure engineering. Although rare, some macroscopic RNA structures have also been constructed using lipid or polymer materials. Here, we report the first example of an enzymatically generated RNA membrane. This robust and free-standing RNA membrane ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5367
更新日期:2014-07-04 00:00:00
abstract::Effective prevention strategies will be essential in reducing disease burden due to bacterial infections. Here we harness the specificity and rapid-acting properties of bacteriophages as a potential prophylaxis therapy for cholera, a severely dehydrating disease caused by Vibrio cholerae. To this end, we test a cockta...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14187
更新日期:2017-02-01 00:00:00
abstract::Fibrosis due to extracellular matrix (ECM) secretion from myofibroblasts complicates many chronic liver diseases causing scarring and organ failure. Integrin-dependent interaction with scar ECM promotes pro-fibrotic features. However, the pathological intracellular mechanism in liver myofibroblasts is not completely u...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12502
更新日期:2016-08-18 00:00:00
abstract::Taxanes are the only chemotherapies used to treat patients with metastatic castration-resistant prostate cancer (CRPC). Despite the initial efficacy of taxanes in treating CRPC, all patients ultimately fail due to the development of drug resistance. In this study, we show that ERG overexpression in in vitro and in viv...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6548
更新日期:2014-11-25 00:00:00
abstract::To perform their computational function, genetic circuits change states through a symphony of genetic parts that turn regulator expression on and off. Debugging is frustrated by an inability to characterize parts in the context of the circuit and identify the origins of failures. Here, we take snapshots of a large gen...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18630-2
更新日期:2020-10-05 00:00:00
abstract::Several of the steps in protein synthesis on the ribosome utilize hydrolysis of guanosine triphosphate (GTP) as the driving force. This reaction is catalyzed by translation factors that become activated upon binding to the ribosome. The recently determined crystal structure of an elongation factor-Tu ternary complex b...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2741
更新日期:2013-01-01 00:00:00
abstract::Complex oxide heterointerfaces and van der Waals heterostructures present two versatile but intrinsically different platforms for exploring emergent quantum phenomena and designing new functionalities. The rich opportunity offered by the synergy between these two classes of materials, however, is yet to be charted. He...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15191-2
更新日期:2020-03-17 00:00:00
abstract::Although fibroblast heterogeneity is recognized in primary tumors, both its characterization in and its impact on metastases remain unknown. Here, combining flow cytometry, immunohistochemistry and RNA-sequencing on breast cancer samples, we identify four Cancer-Associated Fibroblast (CAF) subpopulations in metastatic...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-14134-w
更新日期:2020-01-21 00:00:00
abstract::Epilepsy is one of the most common neurological disorders, yet its pathophysiology is poorly understood due to the high complexity of affected neuronal circuits. To identify dysfunctional neuronal subtypes underlying seizure activity in the human brain, we have performed single-nucleus transcriptomics analysis of >110...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18752-7
更新日期:2020-10-07 00:00:00
abstract::Monolayer molybdenum disulfide (MoS2) has attracted tremendous attention due to its promising applications in high-performance field-effect transistors, phototransistors, spintronic devices and nonlinear optics. The enhanced photoluminescence effect in monolayer MoS2 was discovered and, as a strong tool, was employed ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6246
更新日期:2014-11-18 00:00:00
abstract::Carbon coating is a simple, effective and common technique for improving the conductivity of active materials in lithium ion batteries. However, carbon coating provides a strong reducing atmosphere and many factors remain unclear concerning the interface nature and underlying interaction mechanism that occurs between ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4415
更新日期:2014-03-05 00:00:00
abstract::Over the last century the North Anatolian Fault Zone in Turkey has produced a remarkable sequence of large earthquakes. These events have now left an earthquake gap south of Istanbul and beneath the Marmara Sea, a gap that has not been filled for 250 years. Here we investigate the nature of the eastern end of this gap...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2999
更新日期:2013-01-01 00:00:00
abstract::Proteogenomics enable the discovery of novel peptides (from unannotated genomic protein-coding loci) and single amino acid variant peptides (derived from single-nucleotide polymorphisms and mutations). Increasing the reliability of these identifications is crucial to ensure their usefulness for genome annotation and p...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03311-y
更新日期:2018-03-02 00:00:00
abstract::Accurate estimates of the BOLD hemodynamic response function (HRF) are crucial for the interpretation and analysis of event-related functional MRI data. To date, however, there have been no comprehensive measurements of the HRF in white matter (WM) despite increasing evidence that BOLD signals in WM change after a sti...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09076-2
更新日期:2019-03-08 00:00:00
abstract::Temperature measurement is critical for many technological applications and scientific experiments, and different types of thermometers have been developed to detect temperature at macroscopic length scales. However, quantitative measurement of the temperature of nanostructures remains a challenge. Here, we show a new...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5986
更新日期:2014-10-13 00:00:00
abstract::In the original version of this Article, the affiliation details for Antoine Aze, Michalis Fragkos, Stéphane Bocquet, Julien Cau and Marcel Méchali incorrectly omitted 'CNRS and the University of Montpellier'. This has now been corrected in both the PDF and HTML versions of the Article. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-018-02968-9
更新日期:2018-02-05 00:00:00
abstract::Phonons are the main source of relaxation in molecular nanomagnets, and different mechanisms have been proposed in order to explain the wealth of experimental findings. However, very limited experimental investigations on phonons in these systems have been performed so far, yielding no information about their dispersi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15475-7
更新日期:2020-04-09 00:00:00
abstract::Multiple myeloma (MM) is characterized by an uninhibited, clonal growth of plasma cells. While first-degree relatives of patients with MM show an increased risk of MM, the genetic basis of inherited MM susceptibility is incompletely understood. Here we report a genome-wide association study in the Nordic region identi...
journal_title:Nature communications
pub_type: 杂志文章,meta分析,多中心研究
doi:10.1038/ncomms8213
更新日期:2015-05-26 00:00:00
abstract::Expression of oestrogen receptor (ESR1) determines whether a breast cancer patient receives endocrine therapy, but does not guarantee patient response. The molecular factors that define endocrine response in ESR1-positive breast cancer patients remain poorly understood. Here we characterize the DNA methylome of endocr...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8758
更新日期:2015-07-14 00:00:00
abstract::Pulses of tree mortality caused by drought have been reported recently in forests around the globe, but large-scale quantitative evidence is lacking for Europe. Analyzing high-resolution annual satellite-based canopy mortality maps from 1987 to 2016 we here show that excess forest mortality (i.e., canopy mortality exc...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19924-1
更新日期:2020-12-03 00:00:00
abstract::Protein-protein interactions featuring intricate binding epitopes remain challenging targets for synthetic inhibitors. Interactions of NEMO, a scaffolding protein central to NF-κB signaling, exemplify this challenge. Various regulators are known to interact with different coiled coil regions of NEMO, but the topologic...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15576-3
更新日期:2020-04-14 00:00:00
abstract::Gate operations in a quantum information processor are generally realized by tailoring specific periods of free and driven evolution of a quantum system. Unwanted environmental noise, which may in principle be distinct during these two periods, acts to decohere the system and increase the gate error rate. Although the...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3337
更新日期:2013-01-01 00:00:00
abstract::Elemental phosphorus is attracting growing interest across fundamental and applied fields of research. However, atomistic simulations of phosphorus have remained an outstanding challenge. Here, we show that a universally applicable force field for phosphorus can be created by machine learning (ML) from a suitably chos...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19168-z
更新日期:2020-10-29 00:00:00
abstract::Τhe morphology, physiology and immunology, of solid tumors exhibit spatial heterogeneity which complicates our understanding of cancer progression and therapy response. Understanding spatial heterogeneity necessitates high resolution in vivo imaging of anatomical and pathophysiological tumor information. We introduce ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09081-5
更新日期:2019-03-13 00:00:00
abstract::Assembly and maturation of synapses at the Drosophila neuromuscular junction (NMJ) depend on trans-synaptic neurexin/neuroligin signalling, which is promoted by the scaffolding protein Syd-1 binding to neurexin. Here we report that the scaffold protein spinophilin binds to the C-terminal portion of neurexin and is nee...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9362
更新日期:2015-10-16 00:00:00
abstract::Advances in large-area graphene synthesis via chemical vapour deposition on metals like copper were instrumental in the demonstration of graphene-based novel, wafer-scale electronic circuits and proof-of-concept applications such as flexible touch panels. Here, we show that graphene grown by chemical vapour deposition...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5748
更新日期:2014-09-01 00:00:00
abstract::Designing chiral materials to manipulate the biological activities of cells has been an important area not only in chemistry and material science, but also in cell biology and biomedicine. Here, we introduce monolayer plasmonic chiral Au nanoparticle (NP) films modified with L- or D-penicillamine (Pen) to be developed...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02268-8
更新日期:2017-12-08 00:00:00
abstract::Tpt1 is an essential agent of fungal tRNA splicing that removes the 2'-PO4 at the splice junction generated by fungal tRNA ligase. Tpt1 catalyzes a unique two-step reaction whereby the 2'-PO4 attacks NAD+ to form an RNA-2'-phospho-ADP-ribosyl intermediate that undergoes transesterification to yield 2'-OH RNA and ADP-r...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-08211-9
更新日期:2019-01-15 00:00:00
abstract::Recent density-functional theory calculations suggest that codoping TiO2 with donor-acceptor pairs is more effective than monodoping for improving photoelectrochemical water-splitting performance because codoping can reduce charge recombination, improve material quality, enhance light absorption and increase solubilit...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2729
更新日期:2013-01-01 00:00:00