Abstract:
:Among the 33 confirmed Bartonella species to date, more than half are hosted by rodent species, and at least five of them have been involved in human illness causing diverse symptoms including fever, myocarditis, endocarditis, lymphadenitis and hepatitis. In almost all countries, wild rodents are infected by extremely diverse Bartonella strains with a high prevalence. In the present paper, in light of new knowledge on rodent-adapted Bartonella species genomics, we bring together knowledge gained in recent years to have an overview of the impact of rodent-adapted Bartonella infection on humans and to determine how diversity of Bartonella helps to understand their mechanisms of adaptation to rodents and the consequences on human health.
journal_name
Future Microbioljournal_title
Future microbiologyauthors
Buffet JP,Kosoy M,Vayssier-Taussat Mdoi
10.2217/fmb.13.77subject
Has Abstractpub_date
2013-09-01 00:00:00pages
1117-28issue
9eissn
1746-0913issn
1746-0921journal_volume
8pub_type
杂志文章,评审abstract::The emergence of antimicrobial resistance threatens current clinical practice across a range of infection types. Delafloxacin, a non-zwitterionic fluoroquinolone recently approved by the US FDA for the treatment of acute bacterial skin and skin structure infections, has been developed to address some of these challeng...
journal_title:Future microbiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.2217/fmb-2018-0067
更新日期:2018-08-01 00:00:00
abstract:AIMS:We explored changes in antibiotic susceptibility of Serratia marcescens in the last 50 years by comparing isolates collected between 1945 and 1950, and current isolates. MATERIALS & METHODS:Isolates were divided into three groups: environmental, clinical and 'old'. Susceptibility was determined by microdilution. ...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.12.40
更新日期:2012-06-01 00:00:00
abstract::Surgical procedures for the symptomatic removal of the gallbladder and the vermiform appendix have been posited to adversely shift the assemblage of the intestinal microbiome increasing the risk of disease. The associated mechanisms have been linked with dysbiosis of the gut microbiota. Cholecystectomy causes changes ...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2019-0325
更新日期:2020-05-01 00:00:00
abstract::Living organisms adapt to the dynamic external environment for their survival. Environmental adaptation in prokaryotes is thought to be primarily accomplished by signaling events mediated by two-component systems, consisting of histidine kinases and response regulators. However, eukaryotic-like serine/threonine kinase...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.11.62
更新日期:2011-07-01 00:00:00
abstract::Most humans are infected with herpes simplex virus (HSV) type 1 in early childhood and remain latently infected throughout life. While most individuals have mild or no symptoms, some will develop destructive HSV keratitis. Ocular infection with HSV-1 and its associated sequelae account for the majority of corneal blin...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.11.73
更新日期:2011-08-01 00:00:00
abstract:AIM:Raman spectroscopy is an analytical method with a broad range of applications across multiple scientific fields. We report on a possibility to differentiate between two important Gram-positive species commonly found in clinical material - Staphylococcus aureus and Staphylococcus epidermidis - using this rapid nonin...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2016-0224
更新日期:2017-08-01 00:00:00
abstract::The recent years have witnessed significant progress in the development of new drug candidates for the treatment of TB. While many of these are now in clinical trials, continued research is needed in order to sustain the drug discovery pipeline and meet the increasing needs of TB patients. These include shortening tre...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.11.46
更新日期:2011-06-01 00:00:00
abstract::Chlamydial infections cause a wide range of acute and chronic diseases. Chlamydia trachomatis is the most common sexually transmitted bacterium while Chlamydia pneumoniae causes infections of the upper and lower respiratory tract. Chlamydia are obligate, intracellular bacteria with a biphasic developmental cycle that ...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.14.13
更新日期:2014-01-01 00:00:00
abstract::Staphylococcus aureus is a major human pathogen responsible for a wide diversity of infections ranging from localized to life threatening diseases. From 1961 and the emergence of methicillin-resistant S. aureus (MRSA), this bacterium has shown a particular capacity to survive and adapt to drastic environmental changes...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.11.38
更新日期:2011-05-01 00:00:00
abstract::Invasive fungal infections are an important cause of infectious morbidity. Nonculture-based methods are increasingly used for rapid, accurate diagnosis to improve patient outcomes. New and existing DNA amplification platforms have high sensitivity and specificity for direct detection and identification of fungi in cli...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.09.70
更新日期:2009-11-01 00:00:00
abstract::Over the last decade Raman spectroscopy has become established as a physicochemical technique for the rapid identification of microbes. This powerful analytical method generates a spectroscopic fingerprint from the microbial sample, which provides quantitative and qualitative information that can be used to characteri...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.11.89
更新日期:2011-09-01 00:00:00
abstract:AIM:To evaluate and characterize the etiopathogenesis of the fusarial onychomycosis in an ex vivo study through fragments of sterile human nail, without the addition of any nutritional source. MATERIALS & METHODS:The infection and invasion of Fusarium oxysporum in the nail were evaluated by scanning electron microscop...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2018-0245
更新日期:2018-12-01 00:00:00
abstract::Atomic force microscopy (AFM) has recently opened a variety of novel possibilities for imaging and manipulating microbial surfaces in their native environment. While AFM imaging offers a means to visualize surface structures at high resolution and in physiological conditions, AFM force spectroscopy enables researchers...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/17460913.1.4.387
更新日期:2006-12-01 00:00:00
abstract::In light of recent studies based on cultivation-independent methods, it appears that the diversity of Prevotella in human microbiota is greater than was previously assumed from cultivation-based studies, and that the implication of these bacteria in several human diseases was unrecognized. While some Prevotella taxa w...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.10.126
更新日期:2010-11-01 00:00:00
abstract:AIMS:AFN-1252 is a novel inhibitor of FabI, an essential enzyme in Staphylococcus spp. This study was undertaken to assess the safety, tolerability and pharmacokinetic properties of AFN-1252, following oral administration in an ascending dose trial. MATERIALS & METHODS:This was a double-blind, randomized, placebo-cont...
journal_title:Future microbiology
pub_type: 杂志文章,随机对照试验
doi:10.2217/fmb.15.101
更新日期:2015-01-01 00:00:00
abstract::Aim: Antibiotic resistance in Mycobacterium abscessus renders treatment poorly effective. Despite erm(41)-gene-mediated macrolide resistance, treatment with azithromycin or clarithromycin is recommended. It is contested whether macrolides differ in erm(41) induction. We determine whether this is the case. Methods:M. a...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2018-0310
更新日期:2019-06-01 00:00:00
abstract::Evaluation of: Kang S-M, Yoo D-G, Lipatov AS et al.: Induction of long-term protective immune responses by influenza H5N1 virus-like particles. PLoS ONE 4, e4667 (2009). This article describes a long-term protective effect of a vaccine candidate against avian influenza H5N1 that is based on A/Viet Nam1203/04 proteins ...
journal_title:Future microbiology
pub_type: 评论,杂志文章
doi:10.2217/fmb.09.33
更新日期:2009-06-01 00:00:00
abstract::There is evidence to link obesity (and metabolic syndrome) with alterations in gut permeability and microbiota. The underlying mechanisms have been questioned and have prompted this review. We propose that the gut barrier function is a primary driver in maintaining metabolic health with poor health being linked to 'gu...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/FMB.15.54
更新日期:2015-01-01 00:00:00
abstract::Organism-wide approaches examining the genetic mechanisms controlling growth and proliferation have proven to be a powerful tool in the study of pathogenic fungi. For many fungal pathogens techniques to study transcription and protein expression are particularly useful, and offer insights into infection processes by t...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.16.9
更新日期:2016-01-01 00:00:00
abstract::The increasing burden of multidrug-resistant bacteria affects the management of several infections. In order to prescribe adequate antibiotics, clinicians facing severe infections such as hospital-acquired pneumonia (HAP) need to promptly identify the pathogens and know their antibiotic susceptibility profiles (AST), ...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.15.144
更新日期:2016-01-01 00:00:00
abstract::Amoebiasis is a serious infectious disease that is caused by the unicellular parasite, Entamoeba histolytica. This parasite is mainly found in developing countries, and are named owing to its ability to destroy tissues. The molecular mechanisms that regulate the virulence of this parasite are not well understood. In r...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.10.140
更新日期:2010-12-01 00:00:00
abstract::Resistance continues to emerge as a leading cause for antiretroviral treatment failure. Several mutations in HIV reverse transcriptase (RT) confer resistance to non-nucleoside inhibitors (NNRTIs), vital components of antiretroviral combination therapies. Since the majority of mutations are located in the NNRTI binding...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.15.122
更新日期:2015-01-01 00:00:00
abstract::Some intracellular/membranous factors exert intrinsic immunity against viral pathogens. Most recently, SAMHD1 has been shown to be one of these factors. SAMHD1 is a nucleus-localized protein, and mutations in the gene are associated with Aicardi-Goutières syndrome. As a triphosphohydrolase, it depletes the intracellul...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.12.81
更新日期:2012-09-01 00:00:00
abstract:AIM:To develop an alternative quorum quenching therapy against multidrug-resistant Acinetobacter baumannii. METHODS & RESULTS:Activity-guided partially purified fraction (F1) from Glycyrrhiza glabra significantly (p < 0.05) reduced quorum sensing regulated virulence factors of A. baumannii viz. motility, biofilm forma...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.15.107
更新日期:2015-01-01 00:00:00
abstract:AIM:To isolate and characterize the two phenotypically distinct subpopulations from Klebsiella pneumoniae clonal cultures grown in the simulate microgravity environment. MATERIALS & METHODS:Here clonal culture of K. pneumoniae strain ATCC BAA-1705 was grown within a vertically rotating wall vessel bioreactor. Microsco...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2017-0032
更新日期:2017-09-01 00:00:00
abstract:AIM:To understand the relationship between ica, aap and bhp gene expression and the implications in biofilm formation in selected clinical and commensal Staphylococcus epidermidis isolates. MATERIAL & METHODS:Isolates were analyzed regarding their biofilm-forming capacity, biochemical matrix composition, biofilm spati...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2017-0140
更新日期:2018-03-01 00:00:00
abstract:AIM:Presenting the first clinical case of Wickerhamomyces myanmarensis. PATIENTS & METHODS:Yeast cells were isolated from blood and central venous catheter of a 5.5-year-old male subject. API 20C AUX, MALDI-TOF MS, ITS and LSU rDNA sequencing, and our qPCR assay were used for identification and the MIC values were det...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2018-0253
更新日期:2019-03-01 00:00:00
abstract::In this Phase I study, healthy volunteers (n = 24) were randomly allocated to receive either one or two 0.2-g applications per day (12 h apart) of ozenoxacin 2% cream on three different areas of the back for 3 consecutive days. Ozenoxacin concentrations were measured in tape stripping samples (from the stratum corneum...
journal_title:Future microbiology
pub_type: 杂志文章,随机对照试验
doi:10.2217/fmb.14.83
更新日期:2014-01-01 00:00:00
abstract::Aim: We sought to investigate the genetic epidemiological relatedness of carbapenem-resistant Acinetobacter baumannii (CRAB) strains of a suspected outbreak in a Lebanese tertiary care hospital to implement necessary infection prevention and control measures. Methods: Twenty-eight nonduplicate CRAB isolates detected a...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2020-0079
更新日期:2020-10-01 00:00:00
abstract::Infectious disease point-of-care test (ID-POCT) devices are becoming widely available, and in this respect, international quality standards and guidelines are available for consultation once ID-POCT has been implemented into medical institutions. However, specific guidelines for consultation during the initial pre-imp...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2016-0120
更新日期:2017-01-01 00:00:00