The differential effect of clarithromycin and azithromycin on induction of macrolide resistance in Mycobacterium abscessus.

abstract：AIM:To investigate the collective resistance of the bacteria population with resistant horizontal gene transfer under sublethal bactericide pressure. MATERIALS & METHODS:By employing qualitative analysis of ordinary differential equations, particularly bifurcation theory and several numerical simulations, a modified 4...

journal_title：Future microbiology

authors： Xu S,Yang J,Yin C,Zhao X

更新日期：2018-02-01 00:00:00

abstract：:Traditionally, the patients believed to be at highest risk of invasive aspergillosis (IA) are those who are neutropenic due to chemotherapy for hematological malignancy or those undergoing allogeneic hematopoietic stem cell transplantation. However, emerging data show that other patients are vulnerable to IA, even tho...

journal_title：Future microbiology

authors： Sheppard D,Grist LM

更新日期：2010-07-01 00:00:00

abstract：:Helicobacter pylori is arguably one of the most successful pathogens; it colonizes the stomachs of more than half of the human population. Colonization and persistence in such an inhospitable niche requires the presence of exquisite adaptive mechanisms. One of the proteins that contributes significantly to the remarka...

journal_title：Future microbiology

authors： Pich OQ,Merrell DS

更新日期：2013-06-01 00:00:00

abstract：:Temporal and spatial fluctuations in the genotype distribution of human rotaviruses are continuously observed in surveillance studies. New genotypes, such as G9 and G12, have emerged and spread worldwide in a very short time span. In addition, reassortment events have the potential to contribute substantially to genet...

journal_title：Future microbiology

authors： Matthijnssens J,Bilcke J,Ciarlet M,Martella V,Bányai K,Rahman M,Zeller M,Beutels P,Van Damme P,Van Ranst M

更新日期：2009-12-01 00:00:00

abstract：:Streptococcus pneumoniae (the pneumococcus) is a major global cause of human disease. Since the publication of the entire sequence of TIGR4 in 2001, our understanding of this human pathogen has increased significantly. Genetic studies, and the use of mutant strains have refined our understanding of the pathogenic mech...

journal_title：Future microbiology

authors： Preston JA,Dockrell DH

更新日期：2008-04-01 00:00:00

abstract：:Carbapenem-resistant Acinetobacter baumannii (CRAB) is endemic in Greece. CRAB initially emerged in 2000 and since then, carbapenemases still have a crucial role in CRAB appearance, except for a few cases resulting from efflux pump or outer-membrane protein mechanisms. OXA-type carbapenemases present the highest preva...

journal_title：Future microbiology

authors： Karampatakis T,Antachopoulos C,Tsakris A,Roilides E

更新日期：2017-07-01 00:00:00

abstract：:Infections caused by pathogenic Rickettsia species continue to scourge human health across the globe. From the point of entry at the site of transmission by arthropod vectors, hematogenous dissemination of rickettsiae occurs to diverse host tissues leading to 'rickettsial vasculitis' as the salient feature of pathogen...

journal_title：Future microbiology

authors： Narra HP,Sahni A,Walker DH,Sahni SK

更新日期：2020-06-01 00:00:00

abstract：:Evaluation of: Belogurov GA, Vassylyeva MN, Sevostyanova A et al.: Transcription inactivation through local refolding of the RNA polymerase structure. Nature 457, 332-335 (2008) and, Mukhopadhyay J, Das K, Ismail S et al.: The RNA polymerase 'switch region' is a target for inhibitors. Cell 135, 295-307 (2008). Bacteri...

journal_title：Future microbiology

authors： Tupin A,Gualtieri M,Brodolin K,Leonetti JP

更新日期：2009-03-01 00:00:00

abstract：:The genus Asaia has gained much interest lately owing to constant new species discoveries and its role as a potential opportunistic pathogen to humans. Here we describe a transient bacteremia due to Asaia lannensis in a patient with a psychiatric disorder (compulsive self-injection of different substances). Common phe...

journal_title：Future microbiology

authors： Carretto E,Visiello R,Bardaro M,Schivazappa S,Vailati F,Farina C,Barbarini D

更新日期：2016-01-01 00:00:00

abstract：:Human papillomaviruses (HPVs) cause diseases ranging from benign warts to invasive tumors. A subset of these viruses termed 'high risk' infect the cervix where persistent infection can lead to cervical cancer. Although many HPV genomes have been sequenced, knowledge of virus gene expression and its regulation is still...

journal_title：Future microbiology

authors： Graham SV

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:The seriousness to treat burn wounds infected with Pseudomonas aeruginosa led us to examine whether the effect of the carbapenem antibiotic imipenem is enhanced by hyperbaric oxygen (HBO). MATERIALS & METHODS:The effects of HBO (100% O2, 3 ATA, 5 h) in combination with imipenen on bacterial counts of six is...

journal_title：Future microbiology

authors： Lima FL,Joazeiro PP,Lancellotti M,de Hollanda LM,de Araújo Lima B,Linares E,Augusto O,Brocchi M,Giorgio S

更新日期：2015-01-01 00:00:00

abstract：AIM:To isolate and characterize the two phenotypically distinct subpopulations from Klebsiella pneumoniae clonal cultures grown in the simulate microgravity environment. MATERIALS & METHODS:Here clonal culture of K. pneumoniae strain ATCC BAA-1705 was grown within a vertically rotating wall vessel bioreactor. Microsco...

journal_title：Future microbiology

authors： Wang H,Li W,Gu L,Gao X,Ni B,Deng H,Yang R,Han Y

更新日期：2017-09-01 00:00:00

abstract：AIM:The purpose of current study is to find out relationship between cas9 gene and antimicrobial resistance in Campylobacter jejuni NCTC11168. MATERIALS & METHODS:The involvement of the cas9 gene in antimicrobial resistance of C. jejuni was determined by assessment of minimum inhibitory concentration, clustered regula...

journal_title：Future microbiology

authors： Shabbir MA,Wu Q,Shabbir MZ,Sajid A,Ahmed S,Sattar A,Tang Y,Li J,Maan MK,Hao H,Yuan Z

更新日期：2018-12-01 00:00:00

abstract：:Celebrating its 30th anniversary in Budapest this year, the International Immunocompromised Host Society (ICHS) was established to advance the understanding of interactions between host defenses and microbial agents in order to improve the prevention and management of human disease in patients with compromised immune ...

journal_title：Future microbiology

authors： Maertens J,Bryan J

更新日期：2010-12-01 00:00:00

abstract：:Living organisms adapt to the dynamic external environment for their survival. Environmental adaptation in prokaryotes is thought to be primarily accomplished by signaling events mediated by two-component systems, consisting of histidine kinases and response regulators. However, eukaryotic-like serine/threonine kinase...

journal_title：Future microbiology

authors： Burnside K,Rajagopal L

更新日期：2011-07-01 00:00:00

abstract：:The recent years have witnessed significant progress in the development of new drug candidates for the treatment of TB. While many of these are now in clinical trials, continued research is needed in order to sustain the drug discovery pipeline and meet the increasing needs of TB patients. These include shortening tre...

journal_title：Future microbiology

authors： Sala C,Hartkoorn RC

更新日期：2011-06-01 00:00:00

abstract：:The past decade has seen a significant increase in the incidence of invasive fungal infections. The antifungal armamentarium for the treatment of serious fungal infections remains limited. A possible approach to overcoming antifungal drug resistance and high mortality rates seen in severe fungal infections is to combi...

journal_title：Future microbiology

authors： Vazquez JA

更新日期：2007-04-01 00:00:00

abstract：:Aim: In an Emergency Department (ED), the etiological identification of infected subjects is essential. 13 infection-related biomarkers were assessed using a new flow cytometry procedure. Materials & methods: If subjects presented with febrile symptoms at the ED, 13 biomarkers' levels, including CD64 on neutrophils (n...

journal_title：Future microbiology

authors： Bourgoin P,Lediagon G,Arnoux I,Bernot D,Morange PE,Michelet P,Malergue F,Markarian T

更新日期：2020-02-01 00:00:00

abstract：:Cooling towers provide a favorable environment for the proliferation of microorganisms. Cooling towers generate a biofilm and often aerosolize contaminated water, thereby increasing the risk of microorganism dissemination by human inhalation. This pathogen dissemination was first revealed by the epidemics of Legionnai...

journal_title：Future microbiology

authors： Pagnier I,Merchat M,La Scola B

更新日期：2009-06-01 00:00:00

abstract：:Salmonella enterica serovars Typhi and Paratyphi are the causative agents of human typhoid fever. Current typhoid vaccines are ineffective and are not widely used in endemic areas. Greater understanding of host-pathogen interactions during Salmonella infection should facilitate the development of improved vaccines to ...

journal_title：Future microbiology

authors： Pham OH,McSorley SJ

更新日期：2015-01-01 00:00:00

abstract：:Antibiotics are often used in neonates despite the absence of relevant dosing information in drug labels. For neonatal dosing, clinicians must extrapolate data from studies for adults and older children, who have strikingly different physiologies. As a result, dosing extrapolation can lead to increased toxicity or eff...

journal_title：Future microbiology

authors： Rivera-Chaparro ND,Cohen-Wolkowiez M,Greenberg RG

更新日期：2017-09-01 00:00:00

abstract：:Cryptococcus demonstrates predilection for invasion of the brain, but the mechanism by which Cryptococcus crosses the blood-brain barrier (BBB) to cause brain invasion is largely unknown. In order for Cryptococcus to cross the BBB, there must be a way to either cross human brain microvascular endothelial cells, which ...

journal_title：Future microbiology

authors： Tseng HK,Huang TY,Wu AY,Chen HH,Liu CP,Jong A

更新日期：2015-01-01 00:00:00

abstract：:The aggregate of microorganisms residing on the surface of the skin, in the oropharynx and in the GI tract, known as the human microbiota, play a major role as natural reservoirs for bacterial resistance to antibiotics. Fluoroquinolones (FQ) are among the most prescribed antibiotics and a major increase in FQ resistan...

journal_title：Future microbiology

authors： de Lastours V,Fantin B

更新日期：2015-01-01 00:00:00

abstract：:Most humans are infected with herpes simplex virus (HSV) type 1 in early childhood and remain latently infected throughout life. While most individuals have mild or no symptoms, some will develop destructive HSV keratitis. Ocular infection with HSV-1 and its associated sequelae account for the majority of corneal blin...

journal_title：Future microbiology

authors： Al-Dujaili LJ,Clerkin PP,Clement C,McFerrin HE,Bhattacharjee PS,Varnell ED,Kaufman HE,Hill JM

更新日期：2011-08-01 00:00:00

abstract：:Candida albicans, a diploid yeast commensal and opportunist pathogen, has evolved unusual mechanisms for maintenance of genetic diversity in the absence of a complete sexual cycle. These include chromosomal polymorphisms, mitotic recombination events, and gains and losses of heterozygosity, superimposed on a fundament...

journal_title：Future microbiology

authors： Odds FC

更新日期：2010-01-01 00:00:00

abstract：:Coxsackieviruses are important human pathogens, and their interactions with the innate and adaptive immune systems are of particular interest. Many viruses evade some aspects of the innate response, but coxsackieviruses go a step further by actively inducing, and then exploiting, some features of the host cell respons...

journal_title：Future microbiology

authors： Kemball CC,Alirezaei M,Whitton JL

更新日期：2010-09-01 00:00:00

abstract：:The human periodontium health is commonly compromised by chronic inflammatory conditions and has become a major public health concern. Dental plaque, the precursor of periodontal disease, is a complex biofilm consisting mainly of bacteria, but also archaea, protozoa, fungi and viruses. Viruses that specifically infect...

journal_title：Future microbiology

authors： Pinto G,Silva MD,Peddey M,Sillankorva S,Azeredo J

更新日期：2016-10-01 00:00:00

abstract：:European Respiratory Society Congress, Amsterdam, 26-30 September 2015, and CHEST 2015, Montréal, Canada, 24-28 October 2015 With approximately 50,000 deaths in the US and EU attributed to antibacterial resistance each year, together with several million days of hospital care [1], the need to address resistance mechan...

journal_title：Future microbiology

authors： Sethi S,Bryan J

更新日期：2016-01-01 00:00:00

abstract：:The increasing burden of multidrug-resistant bacteria affects the management of several infections. In order to prescribe adequate antibiotics, clinicians facing severe infections such as hospital-acquired pneumonia (HAP) need to promptly identify the pathogens and know their antibiotic susceptibility profiles (AST), ...

journal_title：Future microbiology

authors： Ruppé E,Baud D,Schicklin S,Guigon G,Schrenzel J

更新日期：2016-01-01 00:00:00

abstract：:Folate metabolism of the malaria parasites provides two targets for current antimalarials: dihydrofolate reductase and dihydropteroate synthase. Dihydrofolate reductase inhibitors have been used as antimalarials over the past few decades, often in combination with dihydropteroate synthase inhibitors. Resistance to the...

journal_title：Future microbiology

authors： Yuthavong Y,Kamchonwongpaisan S,Leartsakulpanich U,Chitnumsub P

更新日期：2006-06-01 00:00:00