Abstract:
AIM:Presenting the first clinical case of Wickerhamomyces myanmarensis. PATIENTS & METHODS:Yeast cells were isolated from blood and central venous catheter of a 5.5-year-old male subject. API 20C AUX, MALDI-TOF MS, ITS and LSU rDNA sequencing, and our qPCR assay were used for identification and the MIC values were determined by CLSI M27-A3. RESULTS:ITS and LSU rDNA sequencing identified both isolates as W. myanmarensis, while API 20C AUX and MALDI-TOF MS did not identify them correctly. Our qPCR specifically distinguished W. myanmarensis from W. anomalus. Isolate obtained from blood showed a higher MIC value for fluconazole, voriconazole and posaconazole. CONCLUSION:Utilization of reliable identification tools might reveal the genuine spectrum of opportunistic yeast species.
journal_name
Future Microbioljournal_title
Future microbiologyauthors
Arastehfar A,Bakhtiari M,Daneshnia F,Fang W,Sadati SK,Al-Hatmi AM,Groenewald M,Sharifi-Mehr H,Liao W,Pan W,Zomorodian K,Hagen F,Boekhout Tdoi
10.2217/fmb-2018-0253subject
Has Abstractpub_date
2019-03-01 00:00:00pages
267-274eissn
1746-0913issn
1746-0921journal_volume
14pub_type
杂志文章abstract:AIMS:To investigate whether Cek2 (as Cek1) is involved in the biogenesis of the fungal cell wall and to uncover differences and similitudes between both proteins. MATERIALS & METHODS:We used molecular genetics to characterize the role of Cek2 in MTL-heterozygous cells. RESULTS:Deletion of CEK2 (similar to CEK1) rende...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.15.127
更新日期:2016-01-01 00:00:00
abstract:AIM:To isolate and characterize the two phenotypically distinct subpopulations from Klebsiella pneumoniae clonal cultures grown in the simulate microgravity environment. MATERIALS & METHODS:Here clonal culture of K. pneumoniae strain ATCC BAA-1705 was grown within a vertically rotating wall vessel bioreactor. Microsco...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2017-0032
更新日期:2017-09-01 00:00:00
abstract::Aim:Cryptococcus neoformans is the major agent of cryptococcosis. The main virulence factor is the polysaccharide (PS) capsule. Changes in cryptococcal PS properties have been poorly elucidated. Materials & methods: We analyzed the mechanical properties of secreted PS and intact capsules, using dynamic light scatterin...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2018-0320
更新日期:2019-07-01 00:00:00
abstract::Chronic hepatitis B virus infection is a global health concern as it affects over 240 million people worldwide and an estimated 686,000 people die annually as a result of complications of the disease. With the development of newer antiviral drugs, viral suppression of HBV is achievable, however elimination of HBV from...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb-2016-0128
更新日期:2016-12-01 00:00:00
abstract:AIM:Our aim is to investigate if the clusters of postsurgical mycobacterial infections, reported between 2004 and 2008 in seven geographically distant states in Brazil, were caused by a single mycobacterial strain. MATERIALS & METHODS:Available information from 929 surgical patients was obtained from local health auth...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.10.49
更新日期:2010-06-01 00:00:00
abstract::Background: Sporotrichosis occurs through contact with contaminated soil and plant. However, the incidence of sporotrichosis as a zoonotic epidemic has increased, particularly in Rio de Janeiro. Aim: In this work, we decided to evaluate some T-cell phenotypes involved in the immune response. Materials & methods: We us...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2020-0046
更新日期:2020-09-01 00:00:00
abstract::Aim: To identify intestinal microbiota compositions in elderly functional constipation (FC) patients. Materials & methods: Fecal samples from 61 FC patients and 48 healthy age-matched volunteers were analyzed through 16S rRNA gene sequencing. Results: The intestinal microbiota compositions of FC patients were signific...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2019-0283
更新日期:2020-02-01 00:00:00
abstract:AIM:To quantitatively assess Staphylococcus aureus biofilms. MATERIALS & METHODS:In addition to the qualitative Congo red agar (CRA) method, we used the bioluminescence (BLM), safranine (SAF), crystal violet (CRV) and resazurin (RES) high-throughput microtiter plate-based quantitative assays. RESULTS:60.47% (26/43) o...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.14.33
更新日期:2014-01-01 00:00:00
abstract::Coxsackieviruses are important human pathogens, and their interactions with the innate and adaptive immune systems are of particular interest. Many viruses evade some aspects of the innate response, but coxsackieviruses go a step further by actively inducing, and then exploiting, some features of the host cell respons...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.10.101
更新日期:2010-09-01 00:00:00
abstract::Traditionally, the patients believed to be at highest risk of invasive aspergillosis (IA) are those who are neutropenic due to chemotherapy for hematological malignancy or those undergoing allogeneic hematopoietic stem cell transplantation. However, emerging data show that other patients are vulnerable to IA, even tho...
journal_title:Future microbiology
pub_type:
doi:10.2217/fmb.10.73
更新日期:2010-07-01 00:00:00
abstract:AIM:To investigate the collective resistance of the bacteria population with resistant horizontal gene transfer under sublethal bactericide pressure. MATERIALS & METHODS:By employing qualitative analysis of ordinary differential equations, particularly bifurcation theory and several numerical simulations, a modified 4...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2017-0070
更新日期:2018-02-01 00:00:00
abstract:AIM:The aim was to evaluate the in vitro activity of fosfomycin against common uropathogens in a fosfomycin-naive population in India. METHODS:The authors prospectively collected and tested all consecutive isolates of Escherichia coli and Enterococcus spp. from urine samples between December 2009 and April 2010. RESU...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.13.31
更新日期:2013-05-01 00:00:00
abstract::The human periodontium health is commonly compromised by chronic inflammatory conditions and has become a major public health concern. Dental plaque, the precursor of periodontal disease, is a complex biofilm consisting mainly of bacteria, but also archaea, protozoa, fungi and viruses. Viruses that specifically infect...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb-2016-0081
更新日期:2016-10-01 00:00:00
abstract::Coxiella burnetii is an extremely infectious, zoonotic agent that causes Q fever in humans. With the exception of New Zealand, the bacterium is distributed worldwide. Coxiella is classified as a select agent based on its past and potential use as a bioweapon and its threat to public health. Despite decades of research...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.11.116
更新日期:2011-11-01 00:00:00
abstract::This paper analyzes the most recent reports regarding the direct and indirect effects of the 13-valent pneumococcal conjugate vaccine (PCV13) when administered to infants and young children. PCV13 extends the protective effects reported for the 7-valent pneumococcal conjugate vaccine (PCV7). A further reduction in the...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.15.81
更新日期:2015-01-01 00:00:00
abstract::Hepatitis E virus (HEV) was for many years thought to be found almost exclusively in developing countries, where it is a major health issue. Recent studies have shown that HEV causes acute and chronic infection in developed countries. In these geographical settings, HEV is primarily a porcine zoonosis caused by genoty...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.14.89
更新日期:2014-01-01 00:00:00
abstract::Salmonella enterica is an invasive, facultative intracellular gastrointestinal pathogen causing human diseases such as gastroenteritis and typhoid fever. Virulence-attenuated strains of this pathogen have interesting capacities for the generation of live vaccines. Attenuated live typhoidal and nontyphoidal Salmonella ...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.11.144
更新日期:2012-01-01 00:00:00
abstract:AIM:To assess different concentrations and formulations of topical ozenoxacin using a mouse model of Staphylococcus aureus dermal infection for identification of the best formulation for treating patients with impetigo. MATERIALS & METHODS:The efficacy of ozenoxacin formulations was compared with vehicle control, mupi...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2017-0290
更新日期:2018-05-01 00:00:00
abstract::Mycobacterium tuberculosis is included among a select group of bacteria possessing the capacity for de novo biosynthesis of vitamin B12, the largest and most complex natural organometallic cofactor. The bacillus is also able to scavenge B12 and related corrinoids utilizing an ATP-binding cassette-type protein that is ...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.13.113
更新日期:2013-11-01 00:00:00
abstract::Coxiella burnetii is the etiological agent of Q fever, a worldwide zoonosis that can result in large outbreaks. The birth of genomics and sequencing of C. burnetii strains has revolutionized many fields of study of this infection. Accurate genotyping methods and comparative genomic analysis have enabled description of...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.15.137
更新日期:2016-01-01 00:00:00
abstract::The aggregate of microorganisms residing on the surface of the skin, in the oropharynx and in the GI tract, known as the human microbiota, play a major role as natural reservoirs for bacterial resistance to antibiotics. Fluoroquinolones (FQ) are among the most prescribed antibiotics and a major increase in FQ resistan...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.15.40
更新日期:2015-01-01 00:00:00
abstract::Evaluation of: Mowat E, Butcher J, Lang S, Williams C, Ramage G: Development of a simple model for studying the effects of antifungal agents on multicellular communities of Aspergillus fumigatus. J. Med. Microbiol. 56, 1205-1212 (2007). Many microorganisms possess the innate ability for adhering to biotic and abiotic ...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/17460913.3.1.19
更新日期:2008-02-01 00:00:00
abstract::European Respiratory Society Congress, Amsterdam, 26-30 September 2015, and CHEST 2015, Montréal, Canada, 24-28 October 2015 With approximately 50,000 deaths in the US and EU attributed to antibacterial resistance each year, together with several million days of hospital care [1], the need to address resistance mechan...
journal_title:Future microbiology
pub_type:
doi:10.2217/fmb-2016-0006
更新日期:2016-01-01 00:00:00
abstract:AIM:To understand the relationship between ica, aap and bhp gene expression and the implications in biofilm formation in selected clinical and commensal Staphylococcus epidermidis isolates. MATERIAL & METHODS:Isolates were analyzed regarding their biofilm-forming capacity, biochemical matrix composition, biofilm spati...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2017-0140
更新日期:2018-03-01 00:00:00
abstract::This review focuses on antibodies (Abs) and their function in immune protection, with particular emphasis on microbicidal Abs. Some aspects of Abs and Ab-drug conjugates as targeting therapeutic agents are also discussed. The main aim, however, is devoted to Ab-derived peptides modulating functions of the immune syste...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.15.36
更新日期:2015-01-01 00:00:00
abstract::Cryptococcus demonstrates predilection for invasion of the brain, but the mechanism by which Cryptococcus crosses the blood-brain barrier (BBB) to cause brain invasion is largely unknown. In order for Cryptococcus to cross the BBB, there must be a way to either cross human brain microvascular endothelial cells, which ...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.15.83
更新日期:2015-01-01 00:00:00
abstract::Background: There is increasing evidence of the association between microbiome dysfunction and Parkinson's disease (PD). Moreover, some PD patients suffer from unintentional weight loss (WL) which may precede the motor manifestations of the disease. Materials & methods: Gut microbiota profiling by 16S rRNA gene sequen...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2019-0336
更新日期:2020-09-01 00:00:00
abstract::Over the last decade Raman spectroscopy has become established as a physicochemical technique for the rapid identification of microbes. This powerful analytical method generates a spectroscopic fingerprint from the microbial sample, which provides quantitative and qualitative information that can be used to characteri...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.11.89
更新日期:2011-09-01 00:00:00
abstract::Background: A major focus of tuberculosis drug discovery is aimed at the development of novel antibiotics with activity against drug-resistant strains of Mycobacterium tuberculosis. Results: We have synthesized ten isoniazid derivatives and investigated for antibacterial activity toward M. tuberculosis H37Rv and isoni...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2019-0085
更新日期:2020-07-01 00:00:00
abstract::In light of recent studies based on cultivation-independent methods, it appears that the diversity of Prevotella in human microbiota is greater than was previously assumed from cultivation-based studies, and that the implication of these bacteria in several human diseases was unrecognized. While some Prevotella taxa w...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.10.126
更新日期:2010-11-01 00:00:00