Brain connectivity plasticity in the motor network after ischemic stroke.

Abstract:

:The motor function is controlled by the motor system that comprises a series of cortical and subcortical areas interacting via anatomical connections. The motor function will be disturbed when the stroke lesion impairs either any of these areas or their connections. More and more evidence indicates that the reorganization of the motor network including both areas and their anatomical and functional connectivity might contribute to the motor recovery after stroke. Here, we review recent studies employing models of anatomical, functional, and effective connectivity on neuroimaging data to investigate how ischemic stroke influences the connectivity of motor areas and how changes in connectivity relate to impaired function and functional recovery. We suggest that connectivity changes constitute an important pathophysiological aspect of motor impairment after stroke and important mechanisms of motor recovery. We also demonstrate that therapeutic interventions may facilitate motor recovery after stroke by modulating the connectivity among the motor areas. In conclusion, connectivity analyses improved our understanding of the mechanisms of motor recovery after stroke and may help to design hypothesis-driven treatment strategies and sensitive measures for outcome prediction in stroke patients.

journal_name

Neural Plast

journal_title

Neural plasticity

authors

Jiang L,Xu H,Yu C

doi

10.1155/2013/924192

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

924192

eissn

2090-5904

issn

1687-5443

journal_volume

2013

pub_type

杂志文章,评审
  • Spatial Integration of Somatosensory Inputs during Sensory-Motor Plasticity Phenomena Is Normal in Focal Hand Dystonia.

    abstract:Background:Surround inhibition is a system that sharpens sensation by creating an inhibitory zone around the central core of activation. In the motor system, this mechanism probably contributes to the selection of voluntary movements, and it seems to be lost in dystonia. Objectives. To explore if sensory information is...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2018/4135708

    authors: Terranova C,Rizzo V,Morgante F,Maggio R,Calamuneri A,Chillemi G,Girlanda P,Quartarone A

    更新日期:2018-10-10 00:00:00

  • Acupuncture Reversible Effects on Altered Default Mode Network of Chronic Migraine Accompanied with Clinical Symptom Relief.

    abstract:Objective:To determine whether and how longitudinal acupuncture modulates the impaired default mode network (DMN) in chronic migraine (CM) patients without aura. Methods:Resting-state functional magnetic resonance imaging (fMRI) data from 14 CM patients treated with longitudinal pre- and postacupuncture treatment (PPA...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2019/5047463

    authors: Zou Y,Tang W,Li X,Xu M,Li J

    更新日期:2019-03-18 00:00:00

  • Emerging Roles of Filopodia and Dendritic Spines in Motoneuron Plasticity during Development and Disease.

    abstract::Motoneurons develop extensive dendritic trees for receiving excitatory and inhibitory synaptic inputs to perform a variety of complex motor tasks. At birth, the somatodendritic domains of mouse hypoglossal and lumbar motoneurons have dense filopodia and spines. Consistent with Vaughn's synaptotropic hypothesis, we pro...

    journal_title:Neural plasticity

    pub_type: 杂志文章,评审

    doi:10.1155/2016/3423267

    authors: Kanjhan R,Noakes PG,Bellingham MC

    更新日期:2016-01-01 00:00:00

  • Translational approach to behavioral learning: lessons from cerebellar plasticity.

    abstract::The role of cerebellar plasticity has been increasingly recognized in learning. The privileged relationship between the cerebellum and the inferior olive offers an ideal circuit for attempting to integrate the numerous evidences of neuronal plasticity into a translational perspective. The high learning capacity of the...

    journal_title:Neural plasticity

    pub_type: 杂志文章,评审

    doi:10.1155/2013/853654

    authors: Cheron G,Dan B,Márquez-Ruiz J

    更新日期:2013-01-01 00:00:00

  • Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain.

    abstract::Aging is a complex process strongly determined by genetics. Previous reports have shown that the genome of neuronal cells displays somatic genomic mosaicism including DNA copy number variations (CNVs). CNVs represent a significant source of genetic variation in the human genome and have been implicated in several diso...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2018/2406170

    authors: Villela D,Suemoto CK,Leite R,Pasqualucci CA,Grinberg LT,Pearson P,Rosenberg C

    更新日期:2018-06-28 00:00:00

  • Different Visual Weighting due to Fast or Slow Vestibular Deafferentation: Before and after Schwannoma Surgery.

    abstract:Background:Feedback postural control depends upon information from somatosensation, vision, and the vestibular system that are weighted depending on their relative importance within the central nervous system. Following loss of any sensory component, the weighting changes, e.g., when suffering a vestibular loss, the mo...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2019/4826238

    authors: Tjernström F,Fransson PA,Kahlon B,Karlberg M,Lindberg S,Siesjö P,Magnusson M

    更新日期:2019-02-18 00:00:00

  • Apolipoprotein E antibodies affect the retention of passive avoidance memory in the chick.

    abstract::Isoforms of apolipoprotein E (ApoE) have been implicated as risk factors in Alzheimer's disease. We have, therefore, examined the possible role of ApoE in memory formation, using a one-trial passive avoidance task in day-old chicks. Birds were trained on the task and then at various times pre or post-training were inj...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/NP.1998.29

    authors: Lancashire C,Mileusnic R,Rose SP

    更新日期:1998-07-01 00:00:00

  • In Sickness and in Health: Perineuronal Nets and Synaptic Plasticity in Psychiatric Disorders.

    abstract::Rapidly emerging evidence implicates perineuronal nets (PNNs) and extracellular matrix (ECM) molecules that compose or interact with PNNs, in the pathophysiology of several psychiatric disorders. Studies on schizophrenia, autism spectrum disorders, mood disorders, Alzheimer's disease, and epilepsy point to the involve...

    journal_title:Neural plasticity

    pub_type: 杂志文章,评审

    doi:10.1155/2016/9847696

    authors: Pantazopoulos H,Berretta S

    更新日期:2016-01-01 00:00:00

  • Carbachol-Induced Reduction in the Activity of Adult Male Zebra Finch RA Projection Neurons.

    abstract::Cholinergic mechanism is involved in motor behavior. In songbirds, the robust nucleus of the arcopallium (RA) is a song premotor nucleus in the pallium and receives cholinergic inputs from the basal forebrain. The activity of projection neurons in RA determines song motor behavior. Although many evidences suggest that...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2016/7246827

    authors: Meng W,Wang SH,Li DF

    更新日期:2016-01-01 00:00:00

  • High Frequency of AIFM1 Variants and Phenotype Progression of Auditory Neuropathy in a Chinese Population.

    abstract::To decipher the genotype-phenotype correlation of auditory neuropathy (AN) caused by AIFM1 variations, as well as the phenotype progression of these patients, exploring the potential molecular pathogenic mechanism of AN. A total of 36 families of individuals with AN (50 cases) with AIFM1 variations were recruited and ...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2020/5625768

    authors: Wang H,Bing D,Li J,Xie L,Xiong F,Lan L,Wang D,Guan J,Wang Q

    更新日期:2020-07-01 00:00:00

  • Neurogenesis, exercise, and cognitive late effects of pediatric radiotherapy.

    abstract::Brain cancer is a common type of childhood malignancy, and radiotherapy (RT) is a mainstay of treatment. RT is effective for tumor eradication, and survival rates are high. However, RT damages the brain and disrupts ongoing developmental processes, resulting in debilitating cognitive "late" effects that may take years...

    journal_title:Neural plasticity

    pub_type: 杂志文章,评审

    doi:10.1155/2013/698528

    authors: Rodgers SP,Trevino M,Zawaski JA,Gaber MW,Leasure JL

    更新日期:2013-01-01 00:00:00

  • Manipulation of Auditory Inputs as Rehabilitation Therapy for Maladaptive Auditory Cortical Reorganization.

    abstract::Neurophysiological and neuroimaging data suggest that the brains of not only children but also adults are reorganized based on sensory inputs and behaviors. Plastic changes in the brain are generally beneficial; however, maladaptive cortical reorganization in the auditory cortex may lead to hearing disorders such as t...

    journal_title:Neural plasticity

    pub_type: 杂志文章,评审

    doi:10.1155/2018/2546250

    authors: Okamoto H

    更新日期:2018-05-20 00:00:00

  • Neural Plastic Effects of Cognitive Training on Aging Brain.

    abstract::Increasing research has evidenced that our brain retains a capacity to change in response to experience until late adulthood. This implies that cognitive training can possibly ameliorate age-associated cognitive decline by inducing training-specific neural plastic changes at both neural and behavioral levels. This lon...

    journal_title:Neural plasticity

    pub_type: 杂志文章,随机对照试验

    doi:10.1155/2015/535618

    authors: Leung NT,Tam HM,Chu LW,Kwok TC,Chan F,Lam LC,Woo J,Lee TM

    更新日期:2015-01-01 00:00:00

  • Correlated Resting-State Functional MRI Activity of Frontostriatal, Thalamic, Temporal, and Cerebellar Brain Regions Differentiates Stroke Survivors with High Compared to Low Depressive Symptom Scores.

    abstract:Background:One in three survivors of stroke experience poststroke depression (PSD). PSD has been linked with poorer recovery of function and cognition, yet our understanding of potential mechanisms is currently limited. Alterations in resting-state functional MRI have been investigated to a limited extent. Fluctuations...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2019/2357107

    authors: Goodin P,Lamp G,Vidyasagar R,Connelly A,Rose S,Campbell BCV,Tse T,Ma H,Howells D,Hankey GJ,Davis S,Donnan G,Carey LM

    更新日期:2019-07-28 00:00:00

  • Effects of Transcranial Alternating Current Stimulation on Cognitive Functions in Healthy Young and Older Adults.

    abstract::Recently, transcranial alternating current stimulation (tACS) has emerged as a tool to enhance human cognitive processes. Here, we provide a brief summary of the rationale behind tACS-induced effects on task-relevant brain oscillations and associated cognitive functions and review previous studies in young subjects th...

    journal_title:Neural plasticity

    pub_type: 杂志文章,随机对照试验

    doi:10.1155/2016/4274127

    authors: Antonenko D,Faxel M,Grittner U,Lavidor M,Flöel A

    更新日期:2016-01-01 00:00:00

  • The Role of Acupuncture Improving Cognitive Deficits due to Alzheimer's Disease or Vascular Diseases through Regulating Neuroplasticity.

    abstract::Dementia affects millions of elderly worldwide causing remarkable costs to society, but effective treatment is still lacking. Acupuncture is one of the complementary therapies that has been applied to cognitive deficits such as Alzheimer's disease (AD) and vascular cognitive impairment (VCI), while the underlying mech...

    journal_title:Neural plasticity

    pub_type: 杂志文章,评审

    doi:10.1155/2021/8868447

    authors: Ji S,Duan J,Hou X,Zhou L,Qin W,Niu H,Luo S,Zhang Y,Chan P,Jin X

    更新日期:2021-01-12 00:00:00

  • Effects of Motor Training on Accuracy and Precision of Jaw and Finger Movements.

    abstract:Objective:To compare the effects of training of jaw and finger movements with and without visual feedback on precision and accuracy. Method:Twenty healthy participants (10 men and 10 women; mean age 24.6 ± 0.8 years) performed two tasks: a jaw open-close movement and a finger lifting task with and without visual feedb...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2019/9593464

    authors: Chen Y,Wu S,Tang Z,Zhang J,Wang L,Yu L,Wang K,Svensson P

    更新日期:2019-11-18 00:00:00

  • Microglia TREM2: A Potential Role in the Mechanism of Action of Electroacupuncture in an Alzheimer's Disease Animal Model.

    abstract::Alzheimer's disease (AD) is one of the most serious public health concerns facing the world. Its characteristic feature is neuroinflammation due to microglial activation. Electroacupuncture is one of the therapies employed to improve the condition of patients with AD, although its mechanism of action is still to be de...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2020/8867547

    authors: Li Y,Jiang J,Tang Q,Tian H,Wang S,Wang Z,Liu H,Yang J,Ren J

    更新日期:2020-09-04 00:00:00

  • The Polarization States of Microglia in TBI: A New Paradigm for Pharmacological Intervention.

    abstract::Traumatic brain injury (TBI) is a serious medical and social problem worldwide. Because of the complex pathophysiological mechanisms of TBI, effective pharmacotherapy is still lacking. The microglial cells are resident tissue macrophages located in the brain and have two major polarization states, M1 phenotype and M2 ...

    journal_title:Neural plasticity

    pub_type: 杂志文章,评审

    doi:10.1155/2017/5405104

    authors: Xu H,Wang Z,Li J,Wu H,Peng Y,Fan L,Chen J,Gu C,Yan F,Wang L,Chen G

    更新日期:2017-01-01 00:00:00

  • AMPA receptor trafficking in homeostatic synaptic plasticity: functional molecules and signaling cascades.

    abstract::Homeostatic synaptic plasticity is a negative-feedback response employed to compensate for functional disturbances in the nervous system. Typically, synaptic activity is strengthened when neuronal firing is chronically suppressed or weakened when neuronal activity is chronically elevated. At both the whole cell and en...

    journal_title:Neural plasticity

    pub_type: 杂志文章,评审

    doi:10.1155/2012/825364

    authors: Wang G,Gilbert J,Man HY

    更新日期:2012-01-01 00:00:00

  • Memory effects of benzodiazepines: memory stages and types versus binding-site subtypes.

    abstract::Benzodiazepines are well established as inhibitory modulators of memory processing. This effect is especially prominent when applied before the acquisition phase of a memory task. This minireview concentrates on the putative subtype selectivity of the acquisition-impairing action of benzodiazepines. Namely, recent gen...

    journal_title:Neural plasticity

    pub_type: 杂志文章,评审

    doi:10.1155/NP.2005.289

    authors: Savić MM,Obradović DI,Ugresić ND,Bokonjić DR

    更新日期:2005-01-01 00:00:00

  • Topological Properties of Large-Scale Cortical Networks Based on Multiple Morphological Features in Amnestic Mild Cognitive Impairment.

    abstract::Previous studies have demonstrated that amnestic mild cognitive impairment (aMCI) has disrupted properties of large-scale cortical networks based on cortical thickness and gray matter volume. However, it is largely unknown whether the topological properties of cortical networks based on geometric measures (i.e., sulca...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2016/3462309

    authors: Li Q,Li X,Wang X,Li Y,Li K,Yu Y,Yin C,Li S,Han Y

    更新日期:2016-01-01 00:00:00

  • The gain modulation by N-methyl-D-aspartate in the projection neurons of robust nucleus of the arcopallium in adult zebra finches.

    abstract::The song of zebra finch is stable in life after it was learned successfully. Vocal plasticity is thought to be a motor exploration that can support continuous learning and optimization of performance. The activity of RA, an important pre-motor nucleus in songbird's brain, influences the song directly. This variability...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2012/931780

    authors: Liao SQ,Hou GQ,Pan X,Liao CS,Li DF

    更新日期:2012-01-01 00:00:00

  • Visual Timing of Structured Dance Movements Resembles Auditory Rhythm Perception.

    abstract::Temporal mechanisms for processing auditory musical rhythms are well established, in which a perceived beat is beneficial for timing purposes. It is yet unknown whether such beat-based timing would also underlie visual perception of temporally structured, ecological stimuli connected to music: dance. In this study, we...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2016/1678390

    authors: Su YH,Salazar-López E

    更新日期:2016-01-01 00:00:00

  • Neurosteroids Involvement in the Epigenetic Control of Memory Formation and Storage.

    abstract::Memory is our ability to store and remember past experiences; it is the result of changes in neuronal circuits of specific brain areas as the hippocampus. During memory formation, neurons integrate their functions and increase the strength of their connections, so that synaptic plasticity is improved and consolidated....

    journal_title:Neural plasticity

    pub_type: 杂志文章,评审

    doi:10.1155/2016/5985021

    authors: Colciago A,Magnaghi V

    更新日期:2016-01-01 00:00:00

  • Anxiety in mice: a principal component analysis study.

    abstract::Two principal component analyses of anxiety were undertaken investigating two strains of mice (ABP/Le and C57BL/6ByJ) in two different experiments, both classical tests for assessing anxiety in rodents. The elevated plus-maze and staircase were used for the first experiment, and a free exploratory paradigm and light-d...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2007/35457

    authors: Clément Y,Joubert C,Kopp C,Lepicard EM,Venault P,Misslin R,Cadot M,Chapouthier G

    更新日期:2007-01-01 00:00:00

  • Vagotomy Reduces Insulin Clearance in Obese Mice Programmed by Low-Protein Diet in the Adolescence.

    abstract::The aim of this study was to investigate the effect of subdiaphragmatic vagotomy on insulin sensitivity, secretion, and degradation in metabolic programmed mice, induced by a low-protein diet early in life, followed by exposure to a high-fat diet in adulthood. Weaned 30-day-old C57Bl/6 mice were submitted to a low-pro...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2017/9652978

    authors: Lubaczeuski C,Gonçalves LM,Vettorazzi JF,Kurauti MA,Santos-Silva JC,Bonfleur ML,Boschero AC,Costa-Júnior JM,Carneiro EM

    更新日期:2017-01-01 00:00:00

  • Plasticity of the dorsal "spatial" stream in visually deprived individuals.

    abstract::Studies on visually deprived individuals provide one of the most striking demonstrations that the brain is highly plastic and is able to rewire as a function of the sensory input it receives from the environment. In the current paper, we focus on spatial abilities that are typically related to the dorsal visual pathwa...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2012/687659

    authors: Dormal G,Lepore F,Collignon O

    更新日期:2012-01-01 00:00:00

  • Neurophysiologic and Cognitive Changes Arising from Cognitive Training Interventions in Persons with Mild Cognitive Impairment: A Systematic Review.

    abstract:Background:Previous reviews have generally reported cognitive//behavioral improvements after cognitively oriented treatments (COTs) in persons with MCI. However, comparatively little is known about the neural mechanisms associated with such cognitive improvement. Objective:The primary aim of the current review was to ...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2018/7301530

    authors: Miotto EC,Batista AX,Simon SS,Hampstead BM

    更新日期:2018-12-02 00:00:00

  • Inhibition of Hyperpolarization-Activated Cation Current in Medium-Sized DRG Neurons Contributed to the Antiallodynic Effect of Methylcobalamin in the Rat of a Chronic Compression of the DRG.

    abstract::Recently several lines of evidence demonstrated that methylcobalamin (MeCbl) might have potential analgesic effect in experimental and clinical studies. However, it was reported that MeCbl had no effect on treating lumbar spinal stenosis induced pain. Thus, the effects of short-term and long-term administration of MeC...

    journal_title:Neural plasticity

    pub_type: 杂志文章

    doi:10.1155/2015/197392

    authors: Zhang M,Han W,Zheng J,Meng F,Jiao X,Hu S,Xu H

    更新日期:2015-01-01 00:00:00