Abstract:
:Dementia affects millions of elderly worldwide causing remarkable costs to society, but effective treatment is still lacking. Acupuncture is one of the complementary therapies that has been applied to cognitive deficits such as Alzheimer's disease (AD) and vascular cognitive impairment (VCI), while the underlying mechanisms of its therapeutic efficiency remain elusive. Neuroplasticity is defined as the ability of the nervous system to adapt to internal and external environmental changes, which may support some data to clarify mechanisms how acupuncture improves cognitive impairments. This review summarizes the up-to-date and comprehensive information on the effectiveness of acupuncture treatment on neurogenesis and gliogenesis, synaptic plasticity, related regulatory factors, and signaling pathways, as well as brain network connectivity, to lay ground for fully elucidating the potential mechanism of acupuncture on the regulation of neuroplasticity and promoting its clinical application as a complementary therapy for AD and VCI.
journal_name
Neural Plastjournal_title
Neural plasticityauthors
Ji S,Duan J,Hou X,Zhou L,Qin W,Niu H,Luo S,Zhang Y,Chan P,Jin Xdoi
10.1155/2021/8868447subject
Has Abstractpub_date
2021-01-12 00:00:00pages
8868447eissn
2090-5904issn
1687-5443journal_volume
2021pub_type
杂志文章,评审abstract::Matricellular proteins are secreted, nonstructural proteins that regulate the extracellular matrix (ECM) and interactions between cells through modulation of growth factor signaling, cell adhesion, migration, and proliferation. Despite being well described in the context of nonneuronal tissues, recent studies have rev...
journal_title:Neural plasticity
pub_type: 杂志文章,评审
doi:10.1155/2014/321209
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abstract::Horizontal connections in superficial cortical layers integrate information across sensory maps by connecting related functional columns. It has been hypothesized that these connections mediate cortical reorganization via synaptic plasticity. However, it is not known if the horizontal connections from discontinuous co...
journal_title:Neural plasticity
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journal_title:Neural plasticity
pub_type: 杂志文章,评审
doi:10.1155/2016/3423267
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journal_title:Neural plasticity
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2016/2947136
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2016/6790743
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journal_title:Neural plasticity
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doi:10.1155/2019/2490750
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journal_title:Neural plasticity
pub_type: 杂志文章,评审
doi:10.1155/2012/375148
更新日期:2012-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/NP.2002.177
更新日期:2002-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2008/872456
更新日期:2008-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章,随机对照试验
doi:10.1155/2019/2184398
更新日期:2019-01-15 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2018/9163521
更新日期:2018-04-24 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章,评审
doi:10.1155/2015/434127
更新日期:2015-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2015/197392
更新日期:2015-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2018/4135708
更新日期:2018-10-10 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2016/3462309
更新日期:2016-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章,评审
doi:10.1155/2016/5985021
更新日期:2016-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2018/4960869
更新日期:2018-05-22 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2012/378307
更新日期:2012-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2017/7543686
更新日期:2017-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2015/503079
更新日期:2015-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2013/251308
更新日期:2013-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2009/415135
更新日期:2009-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
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更新日期:2019-11-18 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2015/396908
更新日期:2015-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章,随机对照试验
doi:10.1155/2018/4843985
更新日期:2018-07-04 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2020/8867547
更新日期:2020-09-04 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2020/5625768
更新日期:2020-07-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章,评审
doi:10.1155/2020/8858415
更新日期:2020-08-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章,评审
doi:10.1155/2018/2651918
更新日期:2018-05-06 00:00:00