The destructive combination of Scediosporium apiosperum lung disease and exuberant inflammation in cystic fibrosis.

abstract：:There are multiple aetiologies for childhood bronchiectasis unrelated to cystic fibrosis. Some of these aetiologies, such as those predisposing to recurrent lung infections, e.g. immunodeficiencies, require treatment of the underlying condition and disease-specific pulmonary pathogens within the airway. Regardless of ...

journal_title：Paediatric respiratory reviews

authors： Redding GJ

更新日期：2011-06-01 00:00:00

abstract：:Primary Ciliary Dyskinesia (PCD) is an autosomal recessive genetic condition affecting the function of motile cilia. The upper respiratory tract is lined with ciliated epithelium and hence a hallmark of PCD is the development, from the neonatal period onwards, of persisting secretion retention and suppurative infectio...

journal_title：Paediatric respiratory reviews

authors： Morgan LC,Birman CS

更新日期：2016-03-01 00:00:00

abstract：:Bronchiolitis is a common disease in infancy, mostly due to Respiratory Syncytial Virus and Rhinovirus. In addition to acute infection, viral bronchiolitis is responsible for sequelae including recurrent wheezing and asthma. The analysis of the viral characteristics and of the pathogenesis of the infection shows diffe...

journal_title：Paediatric respiratory reviews

authors： Vandini S,Calamelli E,Faldella G,Lanari M

更新日期：2017-09-01 00:00:00

abstract：:Obesity is a significant public health problem worldwide, and it has been identified as an independent risk factor for asthma in both adults and children. Not only does obesity increase asthma risk, but it is also associated with decreased asthma-related quality of life, worsened symptoms and asthma control, increased...

journal_title：Paediatric respiratory reviews

authors： McLoughlin RF,Berthon BS,Wood LG

更新日期：2020-03-06 00:00:00

abstract：:Bronchiolitis is a common viral disease that significantly affects infants less than 12 months of age. The purpose of this review is to present a review of the current knowledge of the uses of respiratory support in the management of infants with bronchiolitis presenting to hospital. We electronically searched MEDLINE...

journal_title：Paediatric respiratory reviews

authors： Franklin D,Fraser JF,Schibler A

更新日期：2019-04-01 00:00:00

abstract：:The dynamic interaction between the heart and lungs leads to a degree of respiratory co-morbidity including both restrictive and obstructive airway abnormalities, which may be overlooked in children with congenital and acquired heart disease. The improving imaging techniques of the heart, both foetal and post-natal co...

journal_title：Paediatric respiratory reviews

authors： Fitzgerald DA,Sherwood M

更新日期：2007-12-01 00:00:00

abstract：:Childhood respiratory diseases are accompanied by various forms of epithelial repair and remodelling. Respiratory stem cells are likely to be of great importance in these processes but their identification remains uncertain. By contrast, an enormous effort has been made to identify specific markers of stem cells of ot...

journal_title：Paediatric respiratory reviews

authors： Emura M

更新日期：2002-03-01 00:00:00

abstract：:There are many important respiratory manifestations of endocrine and metabolic diseases in children. Acute and chronic pulmonary infections are the most common respiratory abnormalities in patients with diabetes mellitus, although cardiogenic and non-cardiogenic pulmonary oedema are also possible. Pseudohypoaldosteron...

journal_title：Paediatric respiratory reviews

authors： Milla CE,Zirbes J

更新日期：2012-03-01 00:00:00

abstract：:There are hardly any controlled studies in paediatric tracheostomy care; instead, most established standards, procedures and details have been elaborated at the bedside by trial and error. Once the appropriate tube is chosen, tube care consists of tube change, fixation, management of secretions, humidification of insp...

journal_title：Paediatric respiratory reviews

authors： Oberwaldner B,Eber E

更新日期：2006-09-01 00:00:00

abstract：:The development and phenotypic expression of allergic airway disease depends on a complex interaction between genetic and several environmental factors, such as exposure to food, inhalant allergens and non-specific adjuvant factors (e.g. tobacco smoke, air pollution and infections). The first months of life seem to be...

journal_title：Paediatric respiratory reviews

authors： Halken S

更新日期：2003-06-01 00:00:00

abstract：:The obstructive sleep apnoea syndrome (OSAS) is common in children and results in several complications when untreated. Considering that children are undergoing important brain development, recent research has focused on neurocognitive and behavioural (NCB) complications of OSAS. Studies have shown that treatment of p...

journal_title：Paediatric respiratory reviews

authors： Konstantinopoulou S,Tapia IE

更新日期：2016-09-01 00:00:00

abstract：:The lung is continually at risk of exposure to noxious environmental agents and respiratory pathogens. An elaborate series of defence mechanisms have been developed to protect the airways from these insults. The lower respiratory tract is protected by local mucociliary mechanisms that involve the integration of the ci...

journal_title：Paediatric respiratory reviews

authors： Chilvers MA,O'Callaghan C

更新日期：2000-03-01 00:00:00

abstract：:With the advent of improved antenatal imaging over the past 10 years, the diagnosis, assessment and management of congenital cystic lung abnormalities have changed. These were once considered the exclusive domain of the surgeon, who had the authority to operate on all congenital cystic lung abnormalities regardless of...

journal_title：Paediatric respiratory reviews

authors： Fitzgerald DA

更新日期：2007-03-01 00:00:00

abstract：:Community-acquired pneumonia remains a common and serious illness, which affects children of all age groups. The spectrum of causative organisms is wide and it differs according to the age of the patients. With the advent of new and improved diagnostic techniques our understanding of the aetiology of the disease has b...

journal_title：Paediatric respiratory reviews

authors： Sinaniotis CA

更新日期：2004-01-01 00:00:00

abstract：:NICE produced a guideline for the diagnosis and management of CF (NG78) in October 2017. This paper describes the process of producing the guideline and highlights some of the areas covered by it, including ideas for further research and tools that can be used by purchasers to help improve CF care. ...

journal_title：Paediatric respiratory reviews

authors： Walshaw MJ

更新日期：2019-08-01 00:00:00

abstract：:Vocal cord dysfunction is characterised by paradoxical vocal cord adduction that occurs during inspiration, resulting in symptoms of dyspnoea, wheeze, chest or throat tightness and cough. Although the condition is well described in children and adults, confusion with asthma often triggers the use of an aggressive trea...

journal_title：Paediatric respiratory reviews

authors： Noyes BE,Kemp JS

更新日期：2007-06-01 00:00:00

abstract：:The major morbidity and mortality associated with cerebral palsy (CP) relates to respiratory compromise. This manifests through repeated pulmonary aspiration, airway colonization with pathogenic bacteria, the evolution of bronchiectasis and sleep disordered breathing. An accurate assessment involving a multidisciplina...

journal_title：Paediatric respiratory reviews

authors： Fitzgerald DA,Follett J,Van Asperen PP

更新日期：2009-03-01 00:00:00

abstract：:Pneumonia is highly prevalent in both developed and developing countries. In this review we list the main organisms affecting children with pneumonia and we propose a summary of the best possible diagnostic and therapeutic measures. ...

journal_title：Paediatric respiratory reviews

authors： Stein RT,Marostica PJ

更新日期：2006-01-01 00:00:00

abstract：:The concept of personalised medicine is likely to revolutionise the treatment of adult obstructive sleep apnoea as a result of recent advances in the understanding of disease heterogeneity by identifying clinical phenotypes, pathophysiological endotypes, biomarkers and treatable traits. Children with the condition sho...

journal_title：Paediatric respiratory reviews

authors： Siriwardhana LS,Nixon GM,Horne RSC,Edwards BA

更新日期：2020-11-01 00:00:00

abstract：:Despite fundamental advances in the research on respiratory syncytial virus (RSV) since its initial identification almost 60 years ago, recurring failures in developing vaccines and pharmacologic strategies effective in controlling the infection have allowed RSV to become a leading cause of global infant morbidity and...

journal_title：Paediatric respiratory reviews

authors： Brown PM,Schneeberger DL,Piedimonte G

更新日期：2015-09-01 00:00:00

abstract：:The term atelectasis describes a state of collapsed and non-aerated region of the lung parenchyma, which is otherwise normal. This pathological condition is usually associated with several pulmonary and chest disorders and represents a manifestation of the underlying disease, not a disease per se. Atelectasis may occu...

journal_title：Paediatric respiratory reviews

authors： Peroni DG,Boner AL

更新日期：2000-09-01 00:00:00

abstract：INTRODUCTION:Corticosteroids can be used prenatally to mature the fetal lungs and postnatally to treat or prevent chronic lung disease (CLD). Randomised controlled trials have been performed to evaluate the benefits and risks of perinatal corticosteroid therapy. METHODS:Systematic reviews of randomised controlled tria...

journal_title：Paediatric respiratory reviews

authors： Halliday HL

更新日期：2004-01-01 00:00:00

abstract：:Chylothorax is the accumulation of chyle in the pleural space, as a result of damage to the thoracic duct. Chyle is milky fluid enriched with fat secreted from the intestinal cells and lymphatic fluid. Chylothorax in children, is most commonly seen as a complication of cardiothoracic surgery but may occur in newborns ...

journal_title：Paediatric respiratory reviews

authors： Soto-Martinez M,Massie J

更新日期：2009-12-01 00:00:00

abstract：:It is reasonable to suggest that Telemedicine could help in the management of chronic diseases by giving patients more flexibility to remain at home with opportunities to forward electronic data to healthcare professionals, reduce hospital emergency attendances and reduce overall costs. The reality, particularly in cy...

journal_title：Paediatric respiratory reviews

authors： Lenney W

更新日期：2018-03-01 00:00:00

abstract：:Allergic diseases are a public health problem in industrialized countries due to the increasing number of allergies related to Western lifestyle. The multiplicity of organs affected by allergy (skin (atopic dermatitis), airway epithelium (respiratory allergy), and digestive tract (food allergy)) worsens the prognosis ...

journal_title：Paediatric respiratory reviews

authors： Just J

更新日期：2013-06-01 00:00:00

abstract：:Asthma is a common disease in paediatrics and adults with a significant morbidity, mortality, and financial burden worldwide. Asthma is now recognized as a heterogeneous disease and emerging clinical and laboratory research has elucidated understanding of asthma's underlying immunology. The future of asthma is classif...

journal_title：Paediatric respiratory reviews

authors： Gans MD,Gavrilova T

更新日期：2020-11-01 00:00:00

abstract：:Pulmonary arterial (PA) hypertension in preterm infant is an important consequence of chronic lung disease of prematurity (CLD) arising mainly due to impaired alveolar development and dysregulated angiogenesis of the pulmonary circulation. Although PA pressure and resistance in these children normalise by school age, ...

journal_title：Paediatric respiratory reviews

authors： Poon CY,Edwards MO,Kotecha S

更新日期：2013-12-01 00:00:00

abstract：:With increasing survival in cystic fibrosis (CF) there is an increasing need to deal with the desires of CF patients to become parents. In the context of 98% male infertility in CF, new techniques offer the prospect of successful parenthood. For females, successful pregnancy is possible but careful planning is require...

journal_title：Paediatric respiratory reviews

authors： Lyon A,Bilton D

更新日期：2002-09-01 00:00:00

abstract：:Conflict between the demands of the environment in which a child lives and the child's intrinsic sleep signature, produces stress-behaviour difficulties in the child. Distorted development, especially distorted brain development, often leads to distorted intrinsic sleep signatures. The sleep-behaviour outcome, arising...

journal_title：Paediatric respiratory reviews

authors： Nunn K

更新日期：2014-03-01 00:00:00

abstract：:Cardiac abnormalities occur in association with many of the neuromuscular disorders that present in childhood. Genetic defects involving the cytoskeleton, nuclear membrane, and mitochondrial function have all been described in patients with skeletal myopathy and cardiac involvement. The most common classes of neuromus...

journal_title：Paediatric respiratory reviews

authors： Hsu DT

更新日期：2010-03-01 00:00:00