Stem cells of the respiratory tract.

abstract：:The obstructive sleep apnea syndrome is common and its prevalence is expected to increase with the current obesity epidemic. If left untreated, it is associated with important morbidity such as growth failure, neurocognitive impairment, systemic and pulmonary hypertension, and endothelial dysfunction. Recent research ...

journal_title：Paediatric respiratory reviews

authors： Tapia IE,Marcus CL

更新日期：2013-09-01 00:00:00

abstract：AIM:To describe the respiratory and nutritional supportive care and hospitalisations required in the real-world scenario in children with SMA type 1 treated with nusinersen. METHODS:Single-centre observational cohort study of children with SMA1 commencing nusinersen from November 2016 to September 2018. Motor, respira...

journal_title：Paediatric respiratory reviews

authors： Chen KA,Widger J,Teng A,Fitzgerald DA,D'Silva A,Farrar M

更新日期：2020-09-22 00:00:00

abstract：:Advances in the elucidation of cystic fibrosis transmembrane regulator (CFTR) function have resulted in a greater understanding of the relationship between the CF gene defect and clinical disease. The clinical phenotype is influenced by the class of mutation and possibly by other modifier genes. CFTR regulates the vol...

journal_title：Paediatric respiratory reviews

authors： McAuley DF,Elborn JS

更新日期：2000-06-01 00:00:00

abstract：:Polysomnography is an elaborate diagnostic test composed of numerous data-collecting sensors working concomitantly to aid in the evaluation of varied sleep disorders in all age groups. Polysomnography is the study of choice for the assessment of pediatric sleep-disordered breathing, including obstructive sleep apnea s...

journal_title：Paediatric respiratory reviews

authors： Stowe RC,Afolabi-Brown O

更新日期：2020-04-01 00:00:00

abstract：:The dynamic interaction between the heart and lungs leads to a degree of respiratory co-morbidity including both restrictive and obstructive airway abnormalities, which may be overlooked in children with congenital and acquired heart disease. The improving imaging techniques of the heart, both foetal and post-natal co...

journal_title：Paediatric respiratory reviews

authors： Fitzgerald DA,Sherwood M

更新日期：2007-12-01 00:00:00

abstract：:Since preschool wheezing is the common expression of several heterogeneous disorders, identification of children at risk for persistent asthma is particularly challenging. To date, efforts to predict the outcome of preschool wheeze have mainly relied on predictive rules consisting of simple clinical and laboratory par...

journal_title：Paediatric respiratory reviews

authors： Fouzas S,Brand PL

更新日期：2013-03-01 00:00:00

abstract：:Sudden unexpected death is one of the most frequent ways of dying in the first year of life after the neonatal period. It is however, much less frequent after the first birthday. Investigations into the cause of death are very important, for a significant proportion of these sudden deaths can be explained only after a...

journal_title：Paediatric respiratory reviews

authors： Côté A

更新日期：2010-12-01 00:00:00

abstract：:Cystic fibrosis related diabetes (CFRD) is a common complication of cystic fibrosis, caused by a fall in insulin secretion with age in individuals with pancreatic insufficiency. CFRD is associated with worse clinical status and increased mortality. Treatment of CFRD with insulin results in sustained improvements in lu...

journal_title：Paediatric respiratory reviews

authors： Bridges N

更新日期：2013-05-01 00:00:00

abstract：:The major morbidity and mortality associated with cerebral palsy (CP) relates to respiratory compromise. This manifests through repeated pulmonary aspiration, airway colonization with pathogenic bacteria, the evolution of bronchiectasis and sleep disordered breathing. An accurate assessment involving a multidisciplina...

journal_title：Paediatric respiratory reviews

authors： Fitzgerald DA,Follett J,Van Asperen PP

更新日期：2009-03-01 00:00:00

abstract：:The term atelectasis describes a state of collapsed and non-aerated region of the lung parenchyma, which is otherwise normal. This pathological condition is usually associated with several pulmonary and chest disorders and represents a manifestation of the underlying disease, not a disease per se. Atelectasis may occu...

journal_title：Paediatric respiratory reviews

authors： Peroni DG,Boner AL

更新日期：2000-09-01 00:00:00

abstract：:Cough is a common presenting symptom to paediatricians and paediatric respiratory physicians. The causes of chronic cough in childhood are significantly different from those in adults, and a different approach to diagnosis and management is needed. In most cases cause can be identified or a satisfactory label given. T...

journal_title：Paediatric respiratory reviews

authors： Massie J

更新日期：2006-03-01 00:00:00

abstract：:Control of the cardiovascular and respiratory systems undergoes rapid maturation during infancy. Sleep is at a lifetime maximum during this period and has a marked influence on cardiorespiratory function. The mechanisms leading to sudden infant death syndrome (SIDS) may include a failure in the neural integration of t...

journal_title：Paediatric respiratory reviews

authors： Horne RS,Parslow PM,Harding R

更新日期：2004-09-01 00:00:00

abstract：:Renal disease is relatively rare in cystic fibrosis even though the cystic fibrosis transmembrane regulator (CFTR) protein is expressed in abundance in the kidney. Aberrant CFTR expression probably explains the subtle abnormalities in renal concentrating and diluting ability described in cystic fibrosis and possibly t...

journal_title：Paediatric respiratory reviews

authors： Stephens SE,Rigden SP

更新日期：2002-06-01 00:00:00

abstract：:Asthma is a common disease in paediatrics and adults with a significant morbidity, mortality, and financial burden worldwide. Asthma is now recognized as a heterogeneous disease and emerging clinical and laboratory research has elucidated understanding of asthma's underlying immunology. The future of asthma is classif...

journal_title：Paediatric respiratory reviews

authors： Gans MD,Gavrilova T

更新日期：2020-11-01 00:00:00

abstract：:Chylothorax is the accumulation of chyle in the pleural space, as a result of damage to the thoracic duct. Chyle is milky fluid enriched with fat secreted from the intestinal cells and lymphatic fluid. Chylothorax in children, is most commonly seen as a complication of cardiothoracic surgery but may occur in newborns ...

journal_title：Paediatric respiratory reviews

authors： Soto-Martinez M,Massie J

更新日期：2009-12-01 00:00:00

abstract：:Inhaled nitric oxide (iNO) is a selective pulmonary vasodilator. In randomised trials, iNO increased gas exchange modestly and had no effect on the outcome (survival, chronic lung disease, CLD) in very low birth-weight (VLBW) infants. NO is an important component of the innate immune system and a lipid- soluble free r...

journal_title：Paediatric respiratory reviews

authors： Hallman M,Aikio O

更新日期：2004-01-01 00:00:00

abstract：:Whilst substantial progress has been made in the treatment of cystic fibrosis, the disease still carries a significant burden in terms of symptoms, requirement for treatment and early mortality. The last decade has witnessed a new era in the development of small molecule drugs targeting the CFTR protein, which for the...

journal_title：Paediatric respiratory reviews

authors： Harman K,Dobra R,Davies JC

更新日期：2018-03-01 00:00:00

abstract：:Vocal cord dysfunction is characterised by paradoxical vocal cord adduction that occurs during inspiration, resulting in symptoms of dyspnoea, wheeze, chest or throat tightness and cough. Although the condition is well described in children and adults, confusion with asthma often triggers the use of an aggressive trea...

journal_title：Paediatric respiratory reviews

authors： Noyes BE,Kemp JS

更新日期：2007-06-01 00:00:00

abstract：:Newborn screening for cystic fibrosis remains controversial because there is still little agreement that prophylactic interventions provide substantial long-term benefits. In such situations, where there are some medical benefits and the costs are not prohibitive, it is important to consider the psychosocial implicati...

journal_title：Paediatric respiratory reviews

authors： Parsons EP,Bradley DM

更新日期：2003-12-01 00:00:00

abstract：:The current global strategy for control of tuberculosis, Directly Observed Treatment, Short-course (DOTS) focuses, as a priority, on the management of patients with sputum smear positive tuberculosis. As tuberculosis in children is rarely sputum smear positive, this has led many to believe that children are not import...

journal_title：Paediatric respiratory reviews

authors： Enarson DA

更新日期：2004-01-01 00:00:00

abstract：:Air pollution exposure has increased extensively in recent years and there is considerable evidence that exposure to particulate matter can lead to adverse respiratory outcomes. The health impacts of exposure to air pollution during the prenatal period is especially concerning as it can impair organogenesis and organ ...

journal_title：Paediatric respiratory reviews

authors： Korten I,Ramsey K,Latzin P

更新日期：2017-01-01 00:00:00

abstract：:Significant technological advancements have been achieved in radiology with the introduction of a branch speciality known as interventional radiology. Radiology has moved into the therapeutic arena, performing minimally invasive diagnostic and therapeutic procedures. The interventional radiologist can treat certain va...

journal_title：Paediatric respiratory reviews

authors： John P

更新日期：2001-06-01 00:00:00

abstract：:Accumulating data suggest that prenatal compromises leading to intrauterine growth restriction (IUGR) increase the risk for respiratory deficiencies after birth. In this respect, a growing body of epidemiological evidence in infants, children and adults indicates that small for gestational (SGA) birth weight can adver...

journal_title：Paediatric respiratory reviews

authors： Briana DD,Malamitsi-Puchner A

更新日期：2013-12-01 00:00:00

abstract：:Primary ciliary dyskinesia (PCD) is a rare, autosomal recessive condition. The signs and symptoms are due to congenital abnormalities of ciliary structure and function, resulting in impaired mucociliary clearance. This affects the ciliated epithelium lining the nose, sinuses, Eustachian tube and airways. As a conseque...

journal_title：Paediatric respiratory reviews

authors： Hogg C

更新日期：2009-06-01 00:00:00

abstract：:Pediatric pulmonary arterial hypertension (PAH) is an uncommon disease that can occur in neonates, infants, and children, and is associated with high morbidity and mortality. Despite advances in treatment strategies over the last two decades, the underlying structural and functional changes to the pulmonary arterial c...

journal_title：Paediatric respiratory reviews

authors： Lohani O,Colvin KL,Yeager ME

更新日期：2015-09-01 00:00:00

abstract：:The Clinical and Functional Translation of CFTR (CFTR2) project presents a novel approach to clinical and functional annotation of mutations identified in disease-causing genes. Phenotype and genotype information on approximately 40,000 cystic fibrosis (CF) patients were collected from registries and large clinics. Th...

journal_title：Paediatric respiratory reviews

authors： Castellani C,CFTR2 team.

更新日期：2013-05-01 00:00:00

abstract：:Most causes of upper airway obstruction are rare in the neonatal period and during infancy. They may, however, cause major respiratory problems either initially or during the first few weeks of life. It is important to recognise these problems at an early stage so that appropriate measures to overcome airway obstructi...

journal_title：Paediatric respiratory reviews

authors： Dinwiddie R

更新日期：2004-03-01 00:00:00

abstract：:Social Robots are used in different contexts and, in healthcare, they are better known as Socially Assistive Robots. In the context of asthma, the use of Socially Assistive Robots has the potential to increase motivation and engagement to treatment. Other positive roles proposed for Socially Assistive Robots are to pr...

journal_title：Paediatric respiratory reviews

authors： Ferrante G,Vitale G,Licari A,Montalbano L,Pilato G,Infantino I,Augello A,La Grutta S

更新日期：2020-12-05 00:00:00

abstract：:The aim of this study was to review and synthesize the existing knowledge of the effects of ultrafine particles [UFPs] with a specific focus on children's health. An extensive literature search identified 16 studies fulfilling the criteria set for the review. One of the most important findings of the review was that, ...

journal_title：Paediatric respiratory reviews

authors： da Costa E Oliveira JR,Base LH,de Abreu LC,Filho CF,Ferreira C,Morawska L

更新日期：2019-11-01 00:00:00

abstract：:Interpretation of the paediatric chest X-ray may appear intimidating at first but knowledge of a few basic rules and an understanding of how the radiographic appearance may be influenced by age and technique will help the clinician arrive at the correct diagnosis in many cases. A structured and logical approach to X-r...

journal_title：Paediatric respiratory reviews

authors： Arthur R

更新日期：2000-03-01 00:00:00