Respiratory control and arousal in sleeping infants.

Abstract:

:Control of the cardiovascular and respiratory systems undergoes rapid maturation during infancy. Sleep is at a lifetime maximum during this period and has a marked influence on cardiorespiratory function. The mechanisms leading to sudden infant death syndrome (SIDS) may include a failure in the neural integration of the cardiovascular and respiratory systems, with a concomitant failure to arouse from sleep. Studies have shown that sleep states exert a marked influence on respiratory control and arousability. Infants are more arousable in active sleep compared with quiet sleep from both somatosensory and respiratory stimuli. Post-natal and gestational age at birth also have a marked influence on arousability. Arousability is depressed by the major risk factors for SIDS (prone sleeping, maternal smoking, prematurity and recent infection) and is increased by factors that decrease the risk for SIDS (e.g. use of dummies, breastfeeding).

journal_name

Paediatr Respir Rev

authors

Horne RS,Parslow PM,Harding R

doi

10.1016/j.prrv.2004.04.011

keywords:

subject

Has Abstract

pub_date

2004-09-01 00:00:00

pages

190-8

issue

3

eissn

1526-0542

issn

1526-0550

pii

S152605420400051X

journal_volume

5

pub_type

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