The pharmacologic approach to airway clearance: mucoactive agents.

Abstract:

:The term "mucoactive agent" refers to any medication used to improve the clearance of airway secretions. It is not synonymous with the word "mucolytic" as this strictly means a drug that decreases the viscosity of secretions. In many cases, decreased viscosity will adversely affect cough transport. For this reason many of the older mucolytic agents such as acetylcysteine are not effective for the therapy of lung disease and their use is not recommended. I review here the many classes of mucoactive agents and identify a number of medications with great promise for the treatment of chronic airway disease.

journal_name

Paediatr Respir Rev

authors

Rubin BK

doi

10.1016/j.prrv.2006.04.198

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

S215-9

eissn

1526-0542

issn

1526-0550

pii

S1526-0542(06)00245-4

journal_volume

7 Suppl 1

pub_type

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