Community-acquired pneumonia.

abstract：:Cardiac abnormalities occur in association with many of the neuromuscular disorders that present in childhood. Genetic defects involving the cytoskeleton, nuclear membrane, and mitochondrial function have all been described in patients with skeletal myopathy and cardiac involvement. The most common classes of neuromus...

journal_title：Paediatric respiratory reviews

authors： Hsu DT

更新日期：2010-03-01 00:00:00

abstract：:During airflight, cabins are pressurised to 8000ft (2438m) leading to an effective FiO2 of 0.15. This leads to a fall in oxygen saturation in all passengers, and especially those with underlying lung disease. The hypoxic challenge test using a body plethysmograph can predict a need for supplemental oxygen during airfl...

journal_title：Paediatric respiratory reviews

authors： Balfour-Lynn IM

更新日期：2017-01-01 00:00:00

abstract：:During sleep changes in central and peripheral neurological pathways and muscle tone result in unique vulnerabilities in the respiratory system. Abnormalities of the respiratory system that are not apparent in wakefulness can become evident during particular sleep states, making overnight polysomnography (PSG) a valua...

journal_title：Paediatric respiratory reviews

authors： Waters K

更新日期：2008-09-01 00:00:00

abstract：:Pulmonary arterial (PA) hypertension in preterm infant is an important consequence of chronic lung disease of prematurity (CLD) arising mainly due to impaired alveolar development and dysregulated angiogenesis of the pulmonary circulation. Although PA pressure and resistance in these children normalise by school age, ...

journal_title：Paediatric respiratory reviews

authors： Poon CY,Edwards MO,Kotecha S

更新日期：2013-12-01 00:00:00

abstract：:Inhaled nitric oxide (iNO) is a selective pulmonary vasodilator. In randomised trials, iNO increased gas exchange modestly and had no effect on the outcome (survival, chronic lung disease, CLD) in very low birth-weight (VLBW) infants. NO is an important component of the innate immune system and a lipid- soluble free r...

journal_title：Paediatric respiratory reviews

authors： Hallman M,Aikio O

更新日期：2004-01-01 00:00:00

abstract：:Allergic diseases are a public health problem in industrialized countries due to the increasing number of allergies related to Western lifestyle. The multiplicity of organs affected by allergy (skin (atopic dermatitis), airway epithelium (respiratory allergy), and digestive tract (food allergy)) worsens the prognosis ...

journal_title：Paediatric respiratory reviews

authors： Just J

更新日期：2013-06-01 00:00:00

abstract：:Respiratory viruses cause a number of clinical 'syndromes' in the intensive care unit with different viruses being able to produce similar clinical pictures. Our main presenting problems are upper airway (e.g. croup and tracheitis), lower airway with intrapulmonary shunt (e.g. bronchitis and pneumonia), lower airway w...

journal_title：Paediatric respiratory reviews

authors： Roe M,O'Donnell DR,Tasker RC

更新日期：2003-09-01 00:00:00

abstract：:The lung is continually at risk of exposure to noxious environmental agents and respiratory pathogens. An elaborate series of defence mechanisms have been developed to protect the airways from these insults. The lower respiratory tract is protected by local mucociliary mechanisms that involve the integration of the ci...

journal_title：Paediatric respiratory reviews

authors： Chilvers MA,O'Callaghan C

更新日期：2000-03-01 00:00:00

abstract：:Air pollution exposure has increased extensively in recent years and there is considerable evidence that exposure to particulate matter can lead to adverse respiratory outcomes. The health impacts of exposure to air pollution during the prenatal period is especially concerning as it can impair organogenesis and organ ...

journal_title：Paediatric respiratory reviews

authors： Korten I,Ramsey K,Latzin P

更新日期：2017-01-01 00:00:00

abstract：:The range of techniques available to assess respiratory muscles weakness has greatly expanded over recent years. Respiratory muscle tests can be divided into non-invasive tests, such as lung function parameters, maximal static pressures and sniff nasal pressure and invasive tests, such as transdiaphragmatic pressures ...

journal_title：Paediatric respiratory reviews

authors： Fauroux B

更新日期：2003-09-01 00:00:00

abstract：:Despite evidence showing an improvement in nutritional outcomes following diagnosis by newborn screening (NBS) for cystic fibrosis (CF), the impact on pulmonary outcomes has been less clear. In this review the approaches to measurement of early lung function and knowledge gained from NBS CF cohorts will be described. ...

journal_title：Paediatric respiratory reviews

authors： Davies G

更新日期：2020-08-20 00:00:00

abstract：:The concept of personalised medicine is likely to revolutionise the treatment of adult obstructive sleep apnoea as a result of recent advances in the understanding of disease heterogeneity by identifying clinical phenotypes, pathophysiological endotypes, biomarkers and treatable traits. Children with the condition sho...

journal_title：Paediatric respiratory reviews

authors： Siriwardhana LS,Nixon GM,Horne RSC,Edwards BA

更新日期：2020-11-01 00:00:00

abstract：:Social Robots are used in different contexts and, in healthcare, they are better known as Socially Assistive Robots. In the context of asthma, the use of Socially Assistive Robots has the potential to increase motivation and engagement to treatment. Other positive roles proposed for Socially Assistive Robots are to pr...

journal_title：Paediatric respiratory reviews

authors： Ferrante G,Vitale G,Licari A,Montalbano L,Pilato G,Infantino I,Augello A,La Grutta S

更新日期：2020-12-05 00:00:00

abstract：:Advances in the elucidation of cystic fibrosis transmembrane regulator (CFTR) function have resulted in a greater understanding of the relationship between the CF gene defect and clinical disease. The clinical phenotype is influenced by the class of mutation and possibly by other modifier genes. CFTR regulates the vol...

journal_title：Paediatric respiratory reviews

authors： McAuley DF,Elborn JS

更新日期：2000-06-01 00:00:00

abstract：:Asthma is a heterogeneous disease and it is therefore unrealistic to expect that inhaled corticosteroids (ICS) would be appropriate first line preventer therapy for all children with asthma. There is good theoretical and clinical trial evidence demonstrating that leukotriene receptor antagonists (LTRAs) are more effec...

journal_title：Paediatric respiratory reviews

authors： van Asperen PP

更新日期：2011-12-01 00:00:00

abstract：:Bacterial 'colonisation' of the nasopharynx by potential bacterial pathogens is frequent in early childhood and is frequent as part of a dynamic process in which the microbiota of the oral and nasopharynx are established. New understanding recognizes this process is evolving and that competition and likely regulation ...

journal_title：Paediatric respiratory reviews

authors： Pelton SI

更新日期：2012-09-01 00:00:00

abstract：:Interpretation of the paediatric chest X-ray may appear intimidating at first but knowledge of a few basic rules and an understanding of how the radiographic appearance may be influenced by age and technique will help the clinician arrive at the correct diagnosis in many cases. A structured and logical approach to X-r...

journal_title：Paediatric respiratory reviews

authors： Arthur R

更新日期：2000-03-01 00:00:00

abstract：:Sudden unexpected death is one of the most frequent ways of dying in the first year of life after the neonatal period. It is however, much less frequent after the first birthday. Investigations into the cause of death are very important, for a significant proportion of these sudden deaths can be explained only after a...

journal_title：Paediatric respiratory reviews

authors： Côté A

更新日期：2010-12-01 00:00:00

abstract：:Pediatric donation after circulatory death (pDCD) is an established pathway for organ donation. It remains, however, a relatively rare event worldwide, and most clinicians outside of the pediatric intensive care unit (PICU) are unfamiliar with it. The goal of this review is to introduce the processes and concepts of p...

journal_title：Paediatric respiratory reviews

authors： Weiss MJ,Sherry W,Hornby L

更新日期：2019-02-01 00:00:00

abstract：:Since experienced clinicians spend a substantial proportion of their time teaching and supervising trainees, a working knowledge of adult learning is of value. This knowledge will not only make you a more effective teacher, but will be of benefit to you when you are learning new information. There are a number of impo...

journal_title：Paediatric respiratory reviews

authors： Mellis CM

更新日期：2008-06-01 00:00:00

abstract：:Chronic cough has been variably defined as a cough lasting longer than 3, 4 or 8 weeks. Many post viral or pertussis like illnesses are associated with prolonged coughing that resolves over time. Management involves first trying to make a diagnosis and identify the presence of any underlying condition. Targeted treatm...

journal_title：Paediatric respiratory reviews

authors： Shields MD,Doherty GM

更新日期：2013-06-01 00:00:00

abstract：:Newborn screening for cystic fibrosis remains controversial because there is still little agreement that prophylactic interventions provide substantial long-term benefits. In such situations, where there are some medical benefits and the costs are not prohibitive, it is important to consider the psychosocial implicati...

journal_title：Paediatric respiratory reviews

authors： Parsons EP,Bradley DM

更新日期：2003-12-01 00:00:00

abstract：:Regular exercise and habitual physical activity are important for patients with cystic fibrosis (CF). Research has demonstrated the benefits of aerobic, anaerobic, and strength exercise training programs for health and quality of life, however, the CF patient is faced with unique barriers and challenges to participati...

journal_title：Paediatric respiratory reviews

authors： Wilkes DL,Schneiderman JE,Nguyen T,Heale L,Moola F,Ratjen F,Coates AL,Wells GD

更新日期：2009-09-01 00:00:00

abstract：:During the first year of life and particularly the first 6 months autonomic control of the cardio-respiratory system is still undergoing maturation and infants are at risk of cardio-respiratory instability. These instabilities are most marked during sleep, which is important as infants spend the majority of each 24 ho...

journal_title：Paediatric respiratory reviews

authors： Horne RS

更新日期：2014-06-01 00:00:00

abstract：:Control of the cardiovascular and respiratory systems undergoes rapid maturation during infancy. Sleep is at a lifetime maximum during this period and has a marked influence on cardiorespiratory function. The mechanisms leading to sudden infant death syndrome (SIDS) may include a failure in the neural integration of t...

journal_title：Paediatric respiratory reviews

authors： Horne RS,Parslow PM,Harding R

更新日期：2004-09-01 00:00:00

abstract：:Primary ciliary dyskinesia (PCD) is a rare, autosomal recessive condition. The signs and symptoms are due to congenital abnormalities of ciliary structure and function, resulting in impaired mucociliary clearance. This affects the ciliated epithelium lining the nose, sinuses, Eustachian tube and airways. As a conseque...

journal_title：Paediatric respiratory reviews

authors： Hogg C

更新日期：2009-06-01 00:00:00

abstract：:Outdoor air pollution is increasingly identified as a contributor to respiratory and cardiovascular disease. Pro-inflammatory particles and gases are inhaled deep into the lungs, and are associated with impaired lung growth and exacerbations of chronic respiratory diseases. The magnitude of these effects are of intere...

journal_title：Paediatric respiratory reviews

authors： Brugha R,Edmondson C,Davies JC

更新日期：2018-09-01 00:00:00

abstract：:Non-invasive ventilation (NIV) provides significant advantages to the paediatrician who cares for children with chronic ventilatory insufficiency and who would like to manage these children in the home environment. There is a growing experience in the use of NIV in the management of children with upper airway obstruct...

journal_title：Paediatric respiratory reviews

authors： Wallis C

更新日期：2000-06-01 00:00:00

abstract：:Significant technological advancements have been achieved in radiology with the introduction of a branch speciality known as interventional radiology. Radiology has moved into the therapeutic arena, performing minimally invasive diagnostic and therapeutic procedures. The interventional radiologist can treat certain va...

journal_title：Paediatric respiratory reviews

authors： John P

更新日期：2001-06-01 00:00:00

abstract：:The Clinical and Functional Translation of CFTR (CFTR2) project presents a novel approach to clinical and functional annotation of mutations identified in disease-causing genes. Phenotype and genotype information on approximately 40,000 cystic fibrosis (CF) patients were collected from registries and large clinics. Th...

journal_title：Paediatric respiratory reviews

authors： Castellani C,CFTR2 team.

更新日期：2013-05-01 00:00:00