The Laugier-Hunziker syndrome--a clinical review of six cases.

Abstract:

:The Laugier-Hunziker syndrome is an acquired, benign, macular hyperpigmentation of the lips and buccal mucosa. The nails are often involved with the development of melanonychia. Twenty-two previous cases have been recorded in the literature. We present details of six Caucasian patients with the Laugier-Hunziker syndrome who are the first recorded from Britain. They all had acquired, macular hyperpigmentation of the lips and buccal mucosa. In five of these patients longitudinal pigmented bands were found on the nails. None had other family members affected. Although this is the first report of British patients with this syndrome, we believe that the condition is probably more common than is generally recognized.

journal_name

Clin Exp Dermatol

authors

Kemmett D,Ellis J,Spencer MJ,Hunter JA

doi

10.1111/j.1365-2230.1990.tb02044.x

subject

Has Abstract

pub_date

1990-03-01 00:00:00

pages

111-4

issue

2

eissn

0307-6938

issn

1365-2230

journal_volume

15

pub_type

杂志文章
  • Dyschromatosis universalis hereditaria.

    abstract::Dyschromatosis universalis hereditaria is a clinically heterogenous disorder. We report two unrelated Indian patients with dyschromatosis universalis hereditaria, who had generalized and progressive reticulate hyper- and hypo-pigmentation of the skin. The oral mucosa and tongue also showed mottled pigmentation. Intrig...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.2002.01129.x

    authors: Sethuraman G,Srinivas CR,D'Souza M,Thappa DM,Smiles L

    更新日期:2002-09-01 00:00:00

  • The inter-relation between inflammation and epidermal proliferation in normal skin following epicutaneous application of leukotriene-B4--an immunohistochemical study.

    abstract::Topical application of leukotriene-B4 (LTB4) on normal skin has been used as an in-vivo model to investigate cutaneous inflammation and epidermal proliferation, which are important phenomena in the pathogenesis of psoriasis. The aim of the present investigation is to further elucidate the interrelation between inflamm...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1992.tb00249.x

    authors: de Jong EM,van Erp PE,van Vlijmen IM,van de Kerkhof PC

    更新日期:1992-11-01 00:00:00

  • Endogenous ochronosis.

    abstract::Endogenous ochronosis or alkaptonuria is a rare, autosomal recessive disease of tyrosine metabolism that is caused by a deficiency of the enzyme homogentisic acid oxidase. The disease results in the accumulation and deposition of homogentisic acid in the cartilage, eyelids, forehead, cheeks, axillae, genital region, b...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2009.03618.x

    authors: Turgay E,Canat D,Gurel MS,Yuksel T,Baran MF,Demirkesen C

    更新日期:2009-12-01 00:00:00

  • New intragenic and promoter region deletion mutations in FERMT1 underscore genetic homogeneity in Kindler syndrome.

    abstract:BACKGROUND:Kindler syndrome (KS) is a rare autosomal recessive skin disorder, which was recently reclassified as a subtype of epidermolysis bullosa. Despite the fact that loss-of-function mutations in the FERMT1 gene, encoding kindlin-1, have been shown to cause the syndrome in numerous patients, a small number of typi...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.12222

    authors: Fuchs-Telem D,Nousbeck J,Singer A,McGrath JA,Sarig O,Sprecher E

    更新日期:2014-04-01 00:00:00

  • Isoniazid induced pellagra despite pyridoxine supplementation.

    abstract::Although pellagra is a recognized complication of isoniazid therapy, the diagnosis may be overlooked or delayed--sometimes with life-threatening consequences. We report a case of isoniazid-induced pellagra which occurred despite pyridoxine supplementation. Drug withdrawal and supplementation with niacin led to a rapid...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.1999.00444.x

    authors: Darvay A,Basarab T,McGregor JM,Russell-Jones R

    更新日期:1999-05-01 00:00:00

  • Ultrastructural study of clinically uninvolved skin of patients with pemphigus vulgaris.

    abstract::We investigated skin biopsies from pemphigus vulgaris (PV) patients by light, fluorescent and electron microscopy in order to study the ultrastructural appearances of epidermis at the pre-acantholytic stage. The biopsies were obtained from uninvolved forearm skin in 10 patients with PV in the acute stage of the diseas...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1991.tb00401.x

    authors: Grando SA,Terman AK,Stupina AS,Glukhenky BT,Romanenko AB

    更新日期:1991-09-01 00:00:00

  • Neutrophil folliculitis and serum androgen levels.

    abstract::Pruritic folliculitis (PF) is one of the specific dermatoses of pregnancy the aetiology of which remains unknown. Several theories have been proposed, and the most commonly accepted is that it represents a hormonally induced acne, as seen in patients taking progestogenic steroids. This theory led to the proposition th...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.1999.00510.x

    authors: Vaughan Jones SA,Hern S,Black MM

    更新日期:1999-09-01 00:00:00

  • Reticular variant of mid-dermal elastolysis after insertion of a pacemaker.

    abstract::Summary Mid-dermal elastolysis is an unusual process characterized by the absence of the elastic fibres within the mid-dermis. The disappearance of these fibres causes fine wrinkles (type 1) or perifollicular protrusions (type 2) affecting the trunk, neck and arms. There is a female predilection, and most patients hav...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2009.03736.x

    authors: Cutillas E,Ferrando FJ,Martí ME,Mateu A,Rausell N

    更新日期:2010-07-01 00:00:00

  • Coexisting morphoea and granuloma annulare-are the conditions related?

    abstract::Granuloma annulare and localized morphoea are both well described in the dermatological literature. We now present two patients with both of these diseases, a comorbidity rarely described. A possible pathogenic relationship is discussed. ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.1999.00425.x

    authors: Ben-Amitai D,Hodak E,Lapidoth M,David M

    更新日期:1999-03-01 00:00:00

  • Acquired dermal melanocytosis of the face and extremities.

    abstract::Acquired dermal melanocytosis (ADM) is a relatively rare, but well-described disease among adolescent to middle-aged East Asian women, particularly those of Japanese and Chinese descent. Clinically, ADM manifests as multiple punctate and greyish-brown pigmented areas 1-3 mm in diameter occurring on both sides of the f...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.12867

    authors: Ouchi T,Ishii K,Nishikawa T,Ishiko A

    更新日期:2016-08-01 00:00:00

  • Tumour necrosis factor alpha promoter polymorphism at position -308 is not associated with actinic prurigo.

    abstract::Actinic prurigo (AP) has been found to be strongly associated with HLA DR4 and in particular with the DR4 subtype DRB1*0407. However, AP may occur in the absence of HLA-DR4. Furthermore, it has been shown that HLA-DR4 and DRB1*0407, even in association with polymorphic light eruption (PLE), are insufficient for the ex...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.2001.00922.x

    authors: Grabczynska SA,Carey BS,McGregor JM,Hawk JL,Vaughan RW

    更新日期:2001-11-01 00:00:00

  • Seven novel COL7A1 mutations identified in patients with recessive dystrophic epidermolysis bullosa from Mexico.

    abstract::Recessive dystrophic epidermolysis bullosa (RDEB; OMIM #226600) is one of the most devastating subtypes of epidermolysis bullosa, a group of skin and mucous membrane blistering disorders often associated with extracutaneous manifestations. RDEB is caused by mutations in COL7A1, the gene encoding type VII collagen (C7)...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.13407

    authors: Saeidian AH,Youssefian L,Moreno Trevino MG,Fortuna G,Vahidnezhad H,Atanasova VS,Uitto J,Salas-Alanis JC,South AP

    更新日期:2018-07-01 00:00:00

  • Understanding the role of haptoglobin in psoriasis: effects of ultraviolet B.

    abstract:BACKGROUND:Haptoglobin (Hp) is one of the acute phase proteins, whose main function is to bind free haemoglobin (Hb) and transport it to the liver for degradation and iron recycling. In addition to its role as an Hb scavenger, Hp has been shown to behave as an anti-inflammatory, antioxidant and angiogenic factor. We pr...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.12667

    authors: Maresca B,Lembo S,Ayala F,Balato N,Di Caprio R,Mattii M,Raimondo A,Schiattarella M,Abrescia P,Spagnuolo MS,Cigliano L,Balato A

    更新日期:2016-01-01 00:00:00

  • Severe exacerbation of multiple self-healing squamous epithelioma (Ferguson-Smith disease) with radiotherapy, which was successfully treated with acitretin.

    abstract::We describe the challenging case of a patient presenting with extensive, eruptive mid-facial squamous cell carcinomas (SCCs) and keratoacanthomas (KAs) consequent to radiotherapy. Our patient had a personal and family history of multiple KAs and SCCs. Multiple self-healing squamous epithelioma, otherwise known as Ferg...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2009.03668.x

    authors: Robertson SJ,Bashir SJ,Pichert G,Robson A,Whittaker S

    更新日期:2010-06-01 00:00:00

  • Intercellular IgA dermatosis (IgA pemphigus)--two cases illustrating the clinical heterogeneity of this disorder.

    abstract::IgA pemphigus is rare but may be underdiagnosed. We describe two cases, a 50-year-old female with a pustular eruption resembling subcorneal pustular dermatosis and a 55-year-old male with a pruritic vesiculopustular eruption simulating dermatitis herpetiformis. They illustrate the clinical heterogeneity of IgA pemphig...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.1999.00534.x

    authors: Harman KE,Holmes G,Bhogal BS,McFadden J,Black MM

    更新日期:1999-11-01 00:00:00

  • Topical tretinoin: a new treatment for black hairy tongue (lingua villosa nigra).

    abstract::Black hairy tongue is the name given to the appearance of an abnormal coating of the tongue and occurs only in adults. It is the result of hyperkeratosis of the filiform lingual papillae which, on gross examination appear hair-like with a variable tinctorial aspect from yellow-brown to black. The pathogenesis is unkno...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1992.tb00195.x

    authors: Langtry JA,Carr MM,Steele MC,Ive FA

    更新日期:1992-05-01 00:00:00

  • White fibrous papulosis of the neck.

    abstract::We report a case of white fibrous papulosis of the neck in a 70-year-old Iranian woman. To date this recently reported entity has only been described in Japanese patients. This asymptomatic eruption characteristically affects the posterior neck. The pale papules are round to oval 2-3 mm in diameter, and not follicular...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1991.tb00355.x

    authors: Cerio R,Gold S,Jones EW

    更新日期:1991-05-01 00:00:00

  • Characteristics of Staphylococcus aureus colonization in patients with atopic dermatitis in Sri Lanka.

    abstract:BACKGROUND:Colonization of the skin of patients with atopic dermatitis (AD) by Staphylococcus aureus (SA) is associated with more severe disease. AIM:To determine the association of SA colonization patterns and densities in lesional and nonlesional skin in patients with varying severities of AD, and to determine the a...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2010.03962.x

    authors: Gomes PL,Malavige GN,Fernando N,Mahendra MH,Kamaladasa SD,Seneviratne JK,Karunatilaka DH,Ogg GS

    更新日期:2011-03-01 00:00:00

  • Investigation of the mechanism of action of 2% fusidic acid lotion in the treatment of acne vulgaris.

    abstract::We describe the results of a single-centre, double-blind, vehicle-controlled, parallel group study on the quantitative effects of 2% fusidic acid lotion (Fucidin lotion) in facial acne vulgaris. The trial was completed by 52 patients aged 15-25 years with mild to moderate acne who had been randomized to either Fucidin...

    journal_title:Clinical and experimental dermatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Sommer S,Bojar R,Cunliffe WJ,Holland D,Holland KT,Naags H

    更新日期:1997-09-01 00:00:00

  • Anxiety and depression seem less common in patients with autoreactive chronic spontaneous urticaria.

    abstract::Chronic spontaneous urticaria (CSU) is a common and disabling skin disease which is often associated with psychiatric comorbidities such as anxiety and depression. These conditions are widely thought to cause, drive and/or maintain CSU, and have been reported as making an important contribution to the low quality of l...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.12190

    authors: Weller K,Koti I,Makris M,Maurer M

    更新日期:2013-12-01 00:00:00

  • Erysipelas complicating chronic discoid lupus erythematosus of the face--a case report and review of erysipelas.

    abstract::We present a case of erysipelas which complicated chronic discoid lupus erythematosus (CDLE) of the face. The diagnosis and implications for management are discussed. The changing epidemiology and clinical spectrum of erysipelas are reviewed. ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2230.1989.tb00891.x

    authors: Keefe M,Wakeel RA,Kerr RE

    更新日期:1989-01-01 00:00:00

  • Scombrotoxic fish poisoning.

    abstract::We report the case of a 30-year-old patient who developed scombrotoxic fish poisoning after eating cooked fresh tuna. Symptoms included a bright red rash, tightness of the chest, palpitations, anxiety, mild headache and dizziness, all of which resolved spontaneously within 2-3 h. Such poisoning results from the consum...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.1998.00403.x

    authors: Sabroe RA,Kobza Black A

    更新日期:1998-11-01 00:00:00

  • Clinical and histological characterization of vesicular COVID-19 rashes: a prospective study in a tertiary care hospital.

    abstract::COVID-19 is an infectious disease caused by severe acute respiratory coronavirus 2 (SARS-CoV-2). Vesicular skin rashes have been reported as associated with COVID-19, but there is little information about this cutaneous manifestation. We designed a prospective observational study of patients diagnosed with COVID-19 wh...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.14277

    authors: Fernandez-Nieto D,Ortega-Quijano D,Jimenez-Cauhe J,Burgos-Blasco P,de Perosanz-Lobo D,Suarez-Valle A,Cortes-Cuevas JL,Carretero I,Garcia-Del Real C,Fernandez-Guarino M

    更新日期:2020-10-01 00:00:00

  • A novel, simple, validated and reproducible instrument for assessing provocation threshold levels in patients with symptomatic dermographism.

    abstract:BACKGROUND:Symptomatic dermographism is a common urticarial condition. There is a need for an objective method to determine the provocation threshold for patients, in order to facilitate individualized diagnosis and treatment. AIM:To compare the dermal responses evoked by a new type of dermographometer (FricTest) with...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.12107

    authors: Mlynek A,Vieira dos Santos R,Ardelean E,Weller K,Magerl M,Church MK,Maurer M

    更新日期:2013-06-01 00:00:00

  • Subacute cutaneous lupus erythematosus in a patient with Crohn's disease.

    abstract::A case of anti-Ro (SS-A) antibody-positive subacute cutaneous lupus erythematosus (LE) occurring in a 47-year-old male with Crohn's disease is described. This is a previously undescribed association. ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1992.tb00182.x

    authors: Ashworth J

    更新日期:1992-03-01 00:00:00

  • The effect of topical extract of Momordica charantia (bitter gourd) on wound healing in nondiabetic rats and in rats with diabetes induced by streptozotocin.

    abstract:BACKGROUND:Momordica charantia (MC; bitter gourd) is a traditional herb commonly used for its antidiabetic, antioxidant, contraceptive and antibacterial properties. It is also used for the rapid healing of wounds. AIM:To observe the topical effect of MC extract on the wound-healing process in rats with diabetes induce...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2008.03117.x

    authors: Teoh SL,Latiff AA,Das S

    更新日期:2009-10-01 00:00:00

  • Circulating T-helper 17 cells and associated cytokines in psoriasis.

    abstract:BACKGROUND:Recently, a new population of IL-17-producing CD4 T helper (Th) cells, named Th17, was identified and shown to be involved in various inflammatory and autoimmune diseases, including psoriasis. AIM:To determine the frequency of Th17 cells and related cytokines in peripheral blood of patients with psoriasis, ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.12845

    authors: Chhabra S,Narang T,Joshi N,Goel S,Sawatkar G,Saikia B,Dogra S,Bansal F,Minz R

    更新日期:2016-10-01 00:00:00

  • Erythema multiforme-like eruptions associated with etretinate therapy.

    abstract::Mucocutaneous side-effects from etretinate are common and are usually dose-dependent, whereas hypersensitivity drug eruptions are rare. Two patients are described in whom erythema multiforme-like eruptions appeared several days after oral intake of etretinate. In one patient etretinate rechallenge again produced the s...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1989.tb00939.x

    authors: David M,Sandbank M,Lowe NJ

    更新日期:1989-05-01 00:00:00

  • Treatment of cutaneous leishmaniasis with either topical paromomycin or intralesional meglumine antimoniate.

    abstract::Ninety-six patients with a clinical and parasitological diagnosis of cutaneous leishmaniasis were recruited to a comparative randomized clinical trial evaluating the efficacy of topical paromomycin vs. weekly intralesional injections of meglumine antimoniate. The patients were randomly divided into two treatment group...

    journal_title:Clinical and experimental dermatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2230.2003.01169.x

    authors: Faghihi G,Tavakoli-kia R

    更新日期:2003-01-01 00:00:00

  • The use of silicone gel in the treatment of fresh surgical scars: a randomized study.

    abstract:AIM:To evaluate the effectiveness of a silicone gel in treating surgical wounds compared with a control group of the same phenotype and same scar site for which a placebo was advised. METHODS:This was a randomized controlled trial, carried out in a dermatology department of a university hospital. In total, we studied ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2230.2008.03096.x

    authors: de Giorgi V,Sestini S,Mannone F,Papi F,Alfaioli B,Gori A,Lotti T

    更新日期:2009-08-01 00:00:00