Isoniazid induced pellagra despite pyridoxine supplementation.

Abstract:

:Although pellagra is a recognized complication of isoniazid therapy, the diagnosis may be overlooked or delayed--sometimes with life-threatening consequences. We report a case of isoniazid-induced pellagra which occurred despite pyridoxine supplementation. Drug withdrawal and supplementation with niacin led to a rapid and sustained clinical improvement. The possible mechanisms of isoniazid induced pellagra are discussed.

journal_name

Clin Exp Dermatol

authors

Darvay A,Basarab T,McGregor JM,Russell-Jones R

doi

10.1046/j.1365-2230.1999.00444.x

keywords:

subject

Has Abstract

pub_date

1999-05-01 00:00:00

pages

167-9

issue

3

eissn

0307-6938

issn

1365-2230

pii

ced444

journal_volume

24

pub_type

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