Abstract:
:We report a case of localized bullous pemphigoid (BP) in a woman patient with primary lymphoedema tarda. There is only one previous case reported of localized pemphigoid in an area of lymphoedema, this being of the cicatricial variant. Slow circulation in the lymphatic vessels, increased capillary permeability with preferential localization of antibodies in the area, and potential cleavage of the epidermal junction due to increased hydrostatic pressure leading to autoimmunity, have all been advocated as possible pathogenic mechanisms. Nevertheless, we consider that the mechanism by which localized pemphigoid arises on lymphoedema remains elusive, based on a previous case of generalized BP sparing an area of postsurgical lymphoedema.
journal_name
Clin Exp Dermatoljournal_title
Clinical and experimental dermatologyauthors
Perez A,Clements SE,Benton E,Robson A,Bhogal B,Stefanato CM,McGibbon Ddoi
10.1111/j.1365-2230.2009.03722.xsubject
Has Abstractpub_date
2009-12-01 00:00:00pages
e931-3issue
8eissn
0307-6938issn
1365-2230pii
CED3722journal_volume
34pub_type
杂志文章abstract::Subacute cutaneous lupus erythematosus (SCLE) is characterized by annular scaly erythematous plaques in a photosensitive distribution, and the presence of anti-Ro (SSA) and/or anti-La (SSB) antibodies. Most cases of SCLE are idiopathic, but occasional cases may be drug-induced or associated with a hereditary deficienc...
journal_title:Clinical and experimental dermatology
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journal_title:Clinical and experimental dermatology
pub_type: 杂志文章,评审
doi:
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abstract::Human Herpesvirus 8 (HHV-8) has been implicated in the pathogenesis of Kaposi's sarcoma (KS). In this paper we attempted to confirm the connection between dialysis, HHV-8, and KS by examining the case of an elderly haemodialysis nonimmunosuppressed male patient with end-stage renal disease, who developed KS. By using ...
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journal_title:Clinical and experimental dermatology
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journal_title:Clinical and experimental dermatology
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journal_title:Clinical and experimental dermatology
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journal_title:Clinical and experimental dermatology
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journal_title:Clinical and experimental dermatology
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journal_title:Clinical and experimental dermatology
pub_type: 杂志文章,评审
doi:10.1046/j.1365-2230.2002.01148.x
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Recently, a new population of IL-17-producing CD4 T helper (Th) cells, named Th17, was identified and shown to be involved in various inflammatory and autoimmune diseases, including psoriasis. AIM:To determine the frequency of Th17 cells and related cytokines in peripheral blood of patients with psoriasis, ...
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journal_title:Clinical and experimental dermatology
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journal_title:Clinical and experimental dermatology
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更新日期:2019-06-01 00:00:00
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journal_title:Clinical and experimental dermatology
pub_type: 临床试验,杂志文章
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journal_title:Clinical and experimental dermatology
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journal_title:Clinical and experimental dermatology
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