Molecular analysis of Kaposi's sarcoma occurring during haemodialysis.

Abstract:

:Human Herpesvirus 8 (HHV-8) has been implicated in the pathogenesis of Kaposi's sarcoma (KS). In this paper we attempted to confirm the connection between dialysis, HHV-8, and KS by examining the case of an elderly haemodialysis nonimmunosuppressed male patient with end-stage renal disease, who developed KS. By using PCR we have verified the presence of DNA from two different genomic regions (ORF 26 and ORF K1) of HHV-8. In addition, our RT-PCR results suggest active replication of HHV-8 in blood and KS lesions of the patient. Phylogenetic analysis revealed identical DNA sequence to ORF K1, and a close relation to its C1 variant. In conclusion, we document the case of KS and HHV-8 coexistence in a Greek elderly patient undergoing regular haemodialysis. Furthermore, our results indicate that factors other than immunosuppression could lead to KS development possibly due to activation of HHV-8.

journal_name

Clin Exp Dermatol

authors

Metaxa-Mariatou V,Chiras T,Loli A,Gazouli M,Vallis D,Nasioulas G

doi

10.1111/j.1365-2230.2004.01469.x

keywords:

subject

Has Abstract

pub_date

2004-03-01 00:00:00

pages

188-91

issue

2

eissn

0307-6938

issn

1365-2230

pii

1469

journal_volume

29

pub_type

杂志文章
  • Metallothionein I and II gene knock-out mice exhibit reduced tolerance to 24-h sodium lauryl sulphate patch testing.

    abstract:BACKGROUND:Metallothioneins (MTs) are a group of proteins widely distributed in tissues regulating metal metabolism, scavenging free radicals, and taking part in immunological reactions. Knockout mice for MT genes I and II (MT(-/-)) exhibit reduced tolerance to ultraviolet B injury in vivo. Upregulation of MT proteins ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2007.02399.x

    authors: Ma C,Li LF,Zhang BX

    更新日期:2007-07-01 00:00:00

  • Granulomatous variant of chronic pigmented purpuric dermatoses: report of four new cases and an association with hyperlipidaemia.

    abstract::Four patients presenting with chronic pigmented purpuric dermatosis (CPPD) on the limbs were found to have granulomatous inflammation superimposed on the pathological changes of CPPD. Three of the four patients had hyperlipidaemia. Therefore, the granulomatous reaction observed could be associated with hyperlipidaemia...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2007.02462.x

    authors: Lin WL,Kuo TT,Shih PY,Lin WC,Wong WR,Hong HS

    更新日期:2007-09-01 00:00:00

  • Erysipelas complicating chronic discoid lupus erythematosus of the face--a case report and review of erysipelas.

    abstract::We present a case of erysipelas which complicated chronic discoid lupus erythematosus (CDLE) of the face. The diagnosis and implications for management are discussed. The changing epidemiology and clinical spectrum of erysipelas are reviewed. ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2230.1989.tb00891.x

    authors: Keefe M,Wakeel RA,Kerr RE

    更新日期:1989-01-01 00:00:00

  • Nutritional factors and hair loss.

    abstract::The literature reveals what little is known about nutritional factors and hair loss. What we do know emanates from studies in protein-energy malnutrition, starvation, and eating disorders. In otherwise healthy individuals, nutritional factors appear to play a role in subjects with persistent increased hair shedding. H...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2230.2002.01076.x

    authors: Rushton DH

    更新日期:2002-07-01 00:00:00

  • Photodynamic therapy for basal cell carcinomas in organ-transplant recipients.

    abstract::The incidence of nonmelanoma skin cancer is significantly increased in recipients of solid-organ transplants. Photodynamic therapy (PDT) is a well-documented treatment option for superficial and selected nodular basal cell carcinomas (BCCs) in immunocompetent patients, but there are few reports describing PDT of BCCs ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2011.04248.x

    authors: Guleng GE,Helsing P

    更新日期:2012-06-01 00:00:00

  • The role of interleukins 1, 6 and 8 as lymphocyte attractants in the photodermatoses polymorphic light eruption and chronic actinic dermatitis.

    abstract::The two photodermatoses, polymorphic light eruption (PLE) and chronic actinic dermatitis (CAD), are characterized by lymphocyte-rich inflammatory infiltrates, the pathogeneses of which are not fully understood. We have therefore studied suction blister fluid (SBF) samples from patients with these conditions before and...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.1999.00489.x

    authors: Norris P,Bacon K,Bird C,Hawk J,Camp R

    更新日期:1999-07-01 00:00:00

  • Evaluation of the 2-mm punch biopsy in dermatological diagnosis.

    abstract::This prospective study was undertaken to determine whether the 2-mm punch biopsy technique yields specimens of sufficient size and quality to allow a reliable histological diagnosis to be made. A histopathological comparison was made between tissue obtained from a 2-mm punch biopsy and a standard ellipse biopsy taken ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:

    authors: Todd P,Garioch JJ,Humphreys S,Seywright M,Thomson J,du Vivier AW

    更新日期:1996-01-01 00:00:00

  • Risk factors associated with sensitive skin and potential role of lifestyle habits: a cross-sectional study.

    abstract::Sensitive skin (SS) is a widespread condition, but still not completely understood. To identify risk factors that increase the likelihood of SS, 258 women aged between 20 and 65 years old and resident in the Netherlands were surveyed by questionnaire, which included questions on sociodemographic characteristics (age g...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.13133

    authors: Falcone D,Richters RJH,Uzunbajakava NE,van Erp PEJ,van de Kerkhof PCM

    更新日期:2017-08-01 00:00:00

  • Encephalocraniocutaneous lipomatosis (Haberland syndrome) with bilateral cutaneous and visceral involvement.

    abstract::Encephalocraniocutaneous lipomatosis, or Haberland syndrome, is a rare congenital neurocutaneous disease. It is characterized clinically by unilateral lipomatous hamartomata of the scalp, eyelid, and outer globe of the eye, ipsilateral porencephalic cysts with cortical atrophy, cranial asymmetry, marked developmental ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.2003.01329.x

    authors: Rubegni P,Risulo M,Sbano P,Buonocore G,Perrone S,Fimiani M

    更新日期:2003-07-01 00:00:00

  • Narrowband ultraviolet B phototherapy associated with improvement in Netherton syndrome.

    abstract::Netherton syndrome (NS) is a rare and severe autosomal recessive ichthyosis. We report the case of a patient with NS treated successfully with narrowband ultraviolet B (NB-UVB) phototherapy after failure of low-dose oral isotretinoin. A 16-year-old girl born to consanguineous parents presented with severe ichthyosis. ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2011.04231.x

    authors: Maatouk I,Moutran R,Tomb R

    更新日期:2012-06-01 00:00:00

  • Kaposi's varicelliform eruption in a patient with healing second degree burns.

    abstract::A 15-year-old boy with Kaposi's varicelliform eruption complicating healing second degree burns is reported. Clinically, umbilicated vesicles and pustules evolving to extensive erosions appeared over previously burned areas, sparing normal skin. Rapid diagnosis was made on the basis of the presence of multinucleate gi...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审

    doi:

    authors: Bartralot R,García-Patos V,Rodríguez-Cano L,Castells A

    更新日期:1996-03-01 00:00:00

  • The Laugier-Hunziker syndrome--a clinical review of six cases.

    abstract::The Laugier-Hunziker syndrome is an acquired, benign, macular hyperpigmentation of the lips and buccal mucosa. The nails are often involved with the development of melanonychia. Twenty-two previous cases have been recorded in the literature. We present details of six Caucasian patients with the Laugier-Hunziker syndro...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1990.tb02044.x

    authors: Kemmett D,Ellis J,Spencer MJ,Hunter JA

    更新日期:1990-03-01 00:00:00

  • The course of pregnancy and childbirth in three mothers with recessive dystrophic epidermolysis bullosa.

    abstract:BACKGROUND:Recessive dystrophic epidermolysis bullosa (RDEB) is an autosomal recessive skin disease caused by mutations in the type VII collagen gene (COL7A1), resulting in detachment of the entire epidermis due to loss or hypoplasticity of the anchoring fibrils that normally secure the basement membrane to the underly...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2011.04179.x

    authors: Hanafusa T,Tamai K,Umegaki N,Yamaguchi Y,Fukuda S,Nishikawa Y,Yaegashi N,Okuyama R,McGrath JA,Katayama I

    更新日期:2012-01-01 00:00:00

  • Elevated MIA levels in the serum of pregnant women and of children.

    abstract::Recent studies have shown that the protein MIA (melanoma inhibitory activity) is a potent serum marker for malignant melanoma. MIA is expressed in chondrocytes at high levels, and might potentially be elevated during periods of growth in childhood. Therefore, we evaluated MIA serum levels in pregnant women and in grow...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2004.01623.x

    authors: Bosserhoff AK,Küster H,Hein R

    更新日期:2004-11-01 00:00:00

  • Sebaceous gland hyperplasia of the foreskin.

    abstract::Two men, aged in their 20s, presented with multiple, soft, rounded papules on the prepuce. The lesions were centrally umbilicated, resembling molluscum contagiosum, but clearly distinct from Tyson's glands. Surface microscopy showed well-defined, milky-white, bag-shaped structures, which under histological examination...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2008.02998.x

    authors: Ena P,Origa D,Massarelli G

    更新日期:2009-04-01 00:00:00

  • Malignant eccrine spiradenoma: case report and review of the literature, including 15 Japanese cases.

    abstract::Malignant eccrine spiradenoma (MES) is an extremely rare cutaneous malignant tumour. An 86-year-old man presented at our hospital with an enlarging tumour on the dorsum of the left hand. An excisional biopsy was taken and histological examination showed a solid island of cells of two distinct types: cells with abundan...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2230.2008.03072.x

    authors: Tanese K,Sato T,Ishiko A

    更新日期:2010-01-01 00:00:00

  • Time to progression from discoid lupus erythematosus to systemic lupus erythematosus: a retrospective cohort study.

    abstract::Determining the risk of progression to systemic lupus erythematosus (SLE) among patients diagnosed with discoid lupus erythematosus (DLE), and the time frame of this risk, are important clinical questions. Past reports have demonstrated a wide time frame of progression from DLE to SLE, with mean time to progression of...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.14014

    authors: Elman SA,Joyce C,Costenbader KH,Merola JF

    更新日期:2020-01-01 00:00:00

  • Successful treatment of verruca plantaris with a single sublesional injection of interferon-alpha2a.

    abstract:BACKGROUND:Interferons are molecules with antiviral effects, which have been used for the treatment of verruca for many years. AIMS:To determine if sublesional interferon (IFN)-alpha injection offers an effective alternative treatment for common warts. METHODS:We compared the results of single-dose sublesional IFN ap...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2008.02924.x

    authors: Aksakal AB,Ozden MG,Atahan C,Onder M

    更新日期:2009-01-01 00:00:00

  • Polymorphic eruption of pregnancy developing in the puerperium.

    abstract::Polymorphic eruption of pregnancy is an uncommon disorder, usually developing in the third trimester and rapidly resolving in the first few weeks postpartum. It has been suggested that multiple pregnancy and excessive weight gain are associated features. We report a patient with the clinical and histological features ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.2002.01099.x

    authors: Kirkup ME,Dunnill MG

    更新日期:2002-11-01 00:00:00

  • Association of human beta-defensin 1 gene polymorphisms with nonsegmental vitiligo.

    abstract:BACKGROUND:Vitiligo is a pigmentation disorder of autoimmune aetiology. Polymorphisms in beta-defensin genes have been linked to a predisposition to some autoimmune disorders. AIM:To evaluate the role of polymorphisms in DEFB1, the gene encoding for human beta-defensin (HBD)-1 and its 5' untranslated region in nonsegm...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.13697

    authors: Ochoa-Ramírez LA,Becerra-Loaiza DS,Díaz-Camacho SP,Muñoz-Estrada VF,Ríos-Burgueño ER,Prado-Montes de Oca E,Rangel-Villalobos H,Velarde-Félix JS

    更新日期:2019-04-01 00:00:00

  • Subacute cutaneous lupus erythematosus in a patient with Crohn's disease.

    abstract::A case of anti-Ro (SS-A) antibody-positive subacute cutaneous lupus erythematosus (LE) occurring in a 47-year-old male with Crohn's disease is described. This is a previously undescribed association. ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1992.tb00182.x

    authors: Ashworth J

    更新日期:1992-03-01 00:00:00

  • Bilateral and symmetrical palmoplantar punctate keratoses in childhood: a possible clinical clue for an early diagnosis of PTEN hamartoma-tumour syndrome.

    abstract::Palmoplantar punctate keratoses may be the main cutaneous sign of various diseases (porokeratosis punctata palmaris et plantaris, keratosis punctata of the palmar creases, familial punctate palmoplantar keratoderma) or represent a secondary feature [Cowden's syndrome (CS) and Darier's disease]. In CS, such keratoses u...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2008.03136.x

    authors: Ferran M,Bussaglia E,Matias-Guiu X,Pujol RM

    更新日期:2009-07-01 00:00:00

  • Cutaneous melioidosis.

    abstract::Melioidosis is a rare tropical disease caused by infection with the bacterium Burkholderia pseudomallei. It occurs predominantly in south-east Asia, northern and central Australia and central and south America. Patients often present to the internal medicine physicians with a severe, potentially fatal sepsis. We repor...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.2002.01021.x

    authors: Tran D,Tan HH

    更新日期:2002-06-01 00:00:00

  • Psychosomatic cofactors and psychiatric comorbidity in patients with chronic itch.

    abstract:BACKGROUND:While psychosomatic factors may be involved in eliciting as well as coping with chronic itch, psychiatric comorbidity often goes unrecognized in dermatological patients. AIM:To record psychiatric illness, psychiatric and psychotherapeutic pretreatment, and psychotherapy indication in dermatology inpatients ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2006.02211.x

    authors: Schneider G,Driesch G,Heuft G,Evers S,Luger TA,Ständer S

    更新日期:2006-11-01 00:00:00

  • Chondrodermatitis nodularis helicis occurring with systemic sclerosis--an under-reported association?

    abstract::Three cases of chondrodermatitis nodularis helicis (CDNH) in patients with the limited form of systemic sclerosis are described. Two of the three cases were noted during regular follow-up visits and the third case was found as part of a survey of the 21 other patients with systemic sclerosis routinely seen in the depa...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1994.tb01169.x

    authors: Bottomley WW,Goodfield MD

    更新日期:1994-05-01 00:00:00

  • DRESS syndrome caused by efalizumab.

    abstract::We report a case of drug reaction with eosinophilia and systemic symptoms (DRESS) to efalizumab. A 52-year-old man developed a widespread papulovesicular rash after 4 weeks of treatment with efalizumab (1.0 mg/kg/week) for treatment-resistant severe psoriasis. Histology revealed a subepidermal blister with eosinophil-...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2007.02604.x

    authors: White JM,Smith CH,Robson A,Ash G,Barker JN

    更新日期:2008-01-01 00:00:00

  • A case of dermatopathia pigmentosa reticularis with wiry scalp hair and digital fibromatosis resulting from a recurrent KRT14 mutation.

    abstract::We report a patient of Malay ancestry with dermatopathia pigmentosa reticularis (DPR) resulting from a recurrent KRT14 p.R125C mutation. The patient has reticulate hyperpigmentation over his trunk and proximal limbs, together with onychodystrophy. Despite the absence of noncicatricial alopecia, he has acral nonscarrin...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2008.02950.x

    authors: Goh BK,Common JE,Gan WH,Kumarasinghe P

    更新日期:2009-04-01 00:00:00

  • Porokeratosis of Mibelli and immunosuppression.

    abstract::Immunosuppression is recognized to predispose to the development of disseminated superficial actinic porokeratosis and to cause the spread of pre-existing lesions. Porokeratosis of Mibelli has been less frequently described following immunosuppression and we report a further case. ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1991.tb00301.x

    authors: Wilkinson SM,Cartwright PH,English JS

    更新日期:1991-01-01 00:00:00

  • Iododerma and acute respiratory distress with leucocytoclastic vasculitis following the intravenous injection of contrast medium.

    abstract::A 72-year-old woman with chronic renal failure requiring haemodialysis developed acute iododerma twice, after receiving iodide contrast dye for radiological procedures. Iododerma was localized to the face, scalp and elbows and was associated with papular purpura of the legs. Histopathology of the skin lesions showed a...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1990.tb02079.x

    authors: Vaillant L,Pengloan J,Blanchier D,De Muret A,Lorette G

    更新日期:1990-05-01 00:00:00

  • Extensive spinal hyperostosis in a patient receiving isotretinoin--progression after 4 years of etretinate therapy.

    abstract::A patient with Darier's disease was discovered to have persistent, asymptomatic cervical and thoracic spinal hyperostoses after receiving isotretinoin for 7 years. The spinal abnormalities have remained asymptomatic but have now progressed following 4 years of etretinate therapy. The development of skeletal abnormalit...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1989.tb01993.x

    authors: Archer CB,Elias PM,Lowe NJ,Griffiths WA

    更新日期:1989-07-01 00:00:00