The role of interleukins 1, 6 and 8 as lymphocyte attractants in the photodermatoses polymorphic light eruption and chronic actinic dermatitis.

abstract：BACKGROUND:Acne vulgaris is a common chronic skin disease. Inflammation is an important pathogenetic mechanism of acne, and NLRP3 polymorphisms have been reported to be involved in the mediation and occurrence of the inflammation. However, only a few studies on NLRP3 and acne have been reported, and the mechanism remai...

journal_title：Clinical and experimental dermatology

authors： Shen C,Wang QZ,Shen ZY,Yuan HY,Yu WJ,Chen XD,Xu H

更新日期：2019-03-01 00:00:00

abstract：:Two men, aged in their 20s, presented with multiple, soft, rounded papules on the prepuce. The lesions were centrally umbilicated, resembling molluscum contagiosum, but clearly distinct from Tyson's glands. Surface microscopy showed well-defined, milky-white, bag-shaped structures, which under histological examination...

journal_title：Clinical and experimental dermatology

authors： Ena P,Origa D,Massarelli G

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Vitiligo is an acquired pigmentation disorder, which can have a negative effect on patient quality of life (QoL). AIM:To evaluate QoL and psychiatric comorbidity in paediatric patients with vitiligo. METHODS:In total, 30 patients aged 8-18 years who were diagnosed with vitiligo and 30 age- and sex-matched ...

journal_title：Clinical and experimental dermatology

authors： Ucuz I,Altunisik N,Sener S,Turkmen D,Kavuran NA,Marsak M,Colak C

更新日期：2020-02-16 00:00:00

abstract：:We describe a case of a 67-year-old woman with a 1-year history of nail thickening and a non-itchy erythematous scaly eruption on the fingertips. She was diagnosed with psoriasis and started on methotrexate after having had no response to topical calcipotriol. The diagnosis was reviewed after it was revealed by anothe...

journal_title：Clinical and experimental dermatology

authors： Goyal NN,Wong GA

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:This is the first study investigating scabies treatment since 1992 to involve examination of patients with microscopically confirmed scabies. AIM:To assess the efficacy of 1% lindane cream in treating microscopically confirmed scabies, and to determine the utility of dermoscopy-guided skin scraping with mic...

journal_title：Clinical and experimental dermatology

authors： Park SE,Her Y,Kim SS,Kim CW

更新日期：2015-08-01 00:00:00

abstract：:We report a patient of Malay ancestry with dermatopathia pigmentosa reticularis (DPR) resulting from a recurrent KRT14 p.R125C mutation. The patient has reticulate hyperpigmentation over his trunk and proximal limbs, together with onychodystrophy. Despite the absence of noncicatricial alopecia, he has acral nonscarrin...

journal_title：Clinical and experimental dermatology

authors： Goh BK,Common JE,Gan WH,Kumarasinghe P

更新日期：2009-04-01 00:00:00

abstract：:Glyceryl trinitrate (nitroglycerin) has been in use for relief of angina for over a hundred years, but allergic reactions to it or to other organic nitrates rarely feature in the medical literature. Most of the case reports describe reactions to transdermally applied nitroglycerin. We report a case of a localized alle...

journal_title：Clinical and experimental dermatology

authors： Aquilina S,Felice H,Boffa MJ

更新日期：2002-11-01 00:00:00

abstract：:Pityriasis rotunda (PR) is an uncommon chronic dermatosis, which may be idiopathic or may be associated with infections or malignancy. We describe the clinical and biochemical findings of two patients with multiple myeloma, who were incidentally diagnosed with PR, and detail the clinical conditions with which this rar...

journal_title：Clinical and experimental dermatology

authors： van Heerden T,Webb MJ,Barrett CL

更新日期：2014-08-01 00:00:00

abstract：:Idiopathic solar urticaria (SU) is a rare, debilitating photodermatosis, which may be difficult to treat. First-line treatment with antihistamines is effective in mild cases, but remission after phototherapeutic induction of tolerance is often short-lived. Other treatment options include plasma exchange, photopheresis...

journal_title：Clinical and experimental dermatology

authors： Hughes R,Cusack C,Murphy GM,Kirby B

更新日期：2009-12-01 00:00:00

abstract：:We report the case of a 43-year-old woman, a longstanding heavy cigarette smoker, who developed Bürger's disease, leading to mid-thigh amputation of her left leg. After she gave up smoking her disease was arrested but Raynaud's phenomenon continues to affect her hands and right foot. In reviewing the literature, we fo...

journal_title：Clinical and experimental dermatology

authors： Abdullah AN,Keczkes K

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Emerging evidence indicates that plasma interleukin (IL)-17 levels may be associated with increased risk of psoriasis, but the individual published results are inconclusive. AIM:To evaluate IL-17 levels in patients with psoriasis using a meta-analysis of studies comparing IL-17 levels in controls and in pat...

journal_title：Clinical and experimental dermatology

authors： Zhou XY,Bao J,Huang B,Jin Y

更新日期：2017-03-01 00:00:00

abstract：:Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma. We report a case in which identical T-cell clones were identified in both patch and tumour stage lesions and in which the tumorous deposits, containing CD30-positive cells, regressed spontaneously. We discuss the differential diagnosis of the tumorou...

journal_title：Clinical and experimental dermatology

authors： Woodrow SL,Basarab T,Russell Jones R

更新日期：1996-09-01 00:00:00

abstract：:Clear cell acanthoma (CCA) is a benign epidermal tumour with distinctive and uniform clinical and histological features. Although solitary lesions are the rule, some cases of multiple CCA, rarely with more than 10 lesions, have been previously reported. Only 22 cases of multiple CCA have been described in the English ...

journal_title：Clinical and experimental dermatology

authors： Innocenzi D,Barduagni F,Cerio R,Wolter M

更新日期：1994-05-01 00:00:00

abstract：:Drug reactions are common in HIV-1 disease, with the incidence having been reported to increase with increasing stage and with CD4+ T-cell counts below 200/microliters. However, there have been numerous reports of patients in which rechallenge, dosing changes or continued therapy have resulted in no recurrence or else...

journal_title：Clinical and experimental dermatology

authors： Smith KJ,Skelton HG,Yeager J,Ledsky R,Ng TH,Wagner KF

更新日期：1997-05-01 00:00:00

abstract：:Chronic hand eczema (CHE) is a debilitating and distressing disease for patients, the physical symptoms of which are compounded by psychosocial problems. Alitretinoin is an endogenously occurring physiological vitamin A derivative (retinoid) that possesses strong anti-inflammatory and immunomodulatory activity. It is ...

journal_title：Clinical and experimental dermatology

authors： English J,Graham-Brown R,de Sica Chapman A,Alexandroff AB

更新日期：2011-03-01 00:00:00

abstract：:Polymorphic eruption of pregnancy is an uncommon disorder, usually developing in the third trimester and rapidly resolving in the first few weeks postpartum. It has been suggested that multiple pregnancy and excessive weight gain are associated features. We report a patient with the clinical and histological features ...

journal_title：Clinical and experimental dermatology

authors： Kirkup ME,Dunnill MG

更新日期：2002-11-01 00:00:00

abstract：:Black hairy tongue is the name given to the appearance of an abnormal coating of the tongue and occurs only in adults. It is the result of hyperkeratosis of the filiform lingual papillae which, on gross examination appear hair-like with a variable tinctorial aspect from yellow-brown to black. The pathogenesis is unkno...

journal_title：Clinical and experimental dermatology

authors： Langtry JA,Carr MM,Steele MC,Ive FA

更新日期：1992-05-01 00:00:00

abstract：:We report 20 patients who contracted cutaneous leishmaniasis in Central and South America, 18 of them in Belize. The diagnosis was confirmed by the polymerase chain reaction (PCR) in 79% of those tested; the corresponding figure for histology was 62%, touch smear 46%, and culture 11%. Results of PCR can be falsely pos...

journal_title：Clinical and experimental dermatology

authors： Palmer RA,Tran D,Hepburn NC,Ashton RE

更新日期：2001-01-01 00:00:00

abstract：:We report a case of localized bullous pemphigoid (BP) in a woman patient with primary lymphoedema tarda. There is only one previous case reported of localized pemphigoid in an area of lymphoedema, this being of the cicatricial variant. Slow circulation in the lymphatic vessels, increased capillary permeability with pr...

journal_title：Clinical and experimental dermatology

authors： Perez A,Clements SE,Benton E,Robson A,Bhogal B,Stefanato CM,McGibbon D

更新日期：2009-12-01 00:00:00

abstract：:The Ras-Raf-MEK-ERK signalling pathway is frequently dysregulated in human malignancies, as is angiogenesis and the vascular endothelial growth factor receptor (VEGF/VEGFR) pathway. These kinases are therefore important anticancer targets. The novel, oral treatment sorafenib (BAY 43-9006), has been shown to be an inhi...

journal_title：Clinical and experimental dermatology

authors： Lacouture ME,Desai A,Soltani K,Petronic-Rosic V,Laumann AE,Ratain MJ,Stadler WM

更新日期：2006-11-01 00:00:00

abstract：INTRODUCTION:Intraoperative frozen section analysis (IFSA) is traditionally performed for complex and high-risk non-melanoma skin cancer (NMSC) resections, particularly when surgery under a general anaesthetic and a complex reconstruction is required, and where Mohs micrographic surgery (MMS) is not available. METHODS...

journal_title：Clinical and experimental dermatology

authors： Moncrieff MD,Shah AK,Igali L,Garioch JJ

更新日期：2015-12-01 00:00:00

abstract：:Human papilloma virus is a common and often distressing cutaneous disease. It can be therapeutically challenging, especially in immunocompromised patients. We report a case of recalcitrant cutaneous warts that resolved with intravenous cidofovir treatment. The patient was immunocompromised secondary to monoclonal anti...

journal_title：Clinical and experimental dermatology

authors： McAleer MA,Bourke J

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Alopecia areata (AA) is an organ-specific autoimmune disease characterized by folliculotropic T-cell infiltrates around anagen-stage hair follicles. The role of T helper (Th)1 and Th2 cytokines in the pathogenesis of AA have not been established. AIM:To determine whether serum cytokine profiles define the s...

journal_title：Clinical and experimental dermatology

authors： Barahmani N,Lopez A,Babu D,Hernandez M,Donley SE,Duvic M

更新日期：2010-06-01 00:00:00

abstract：:A patient with primary malignant melanoma localized to the right gluteal region is described. Four years later and after intercurrent influenza, disseminated metastases of malignant melanoma to the skin occurred. After a further 6 months melanodermia developed and lasted until the death of the patient (6 months later)...

journal_title：Clinical and experimental dermatology

authors： Péc J,Plank L,Mináriková E,Palencárová E,Rollová Y,Lazárová Z,Auxtová S,Lauko L

更新日期：1993-09-01 00:00:00

abstract：:Ectodermal dysplasias (ED) are developmental disorders affecting tissues of ectodermal origin including hair, nail, teeth and sweat glands. To date, four different types of ectodermal dysplasias involving only hair and nails have been described. In an effort to understand the molecular basis of ED of hair and nails, a...

journal_title：Clinical and experimental dermatology

authors： Naeem M,John P,Ali G,Ahmad W

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Lichen planus (LP) is an inflammatory disease of the skin and mucous membranes. Autoimmunity has been suggested as a possible cause of this disease. The cyclooxygenase enzymes (COX-1, COX-2) are the key enzymes in the conversion of arachidonic acid into prostaglandins. Prostaglandin E2 (PGE2), a key product ...

journal_title：Clinical and experimental dermatology

authors： El-Rifaie AA,Rashed LA,Doss RW

更新日期：2015-12-01 00:00:00

abstract：:A 55-year-old diabetic female treated with a combination of a short- and intermediate-acting insulin, developed sterile furunculoid lesions at the injection sites which eventually healed with atrophic scars. Histopathologically, an initial neutrophilic stage was followed by granulomatous and fibrotic stages. It was co...

journal_title：Clinical and experimental dermatology

authors： Jordaan HF,Sandler M

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Haemangioma of infancy (HOI) is the most frequently occurring benign tumour of infancy. A good, reliable and objective scoring system for haemangioma activity is not yet available. AIM:We have developed a simple system called the Haemangioma Activity Score (HAS) for scoring the (disease) proliferative activ...

journal_title：Clinical and experimental dermatology

authors： Janmohamed SR,de Waard-van der Spek FB,Madern GC,de Laat PC,Hop WC,Oranje AP

更新日期：2011-10-01 00:00:00

abstract：:Hydroxyurea is an anti-tumour agent most commonly used to treat chronic myeloproliferative disorders in doses up to 4 g per day. Dermatological adverse effects reported so far have been observed predominantly in these patients. As we are treating selected psoriasis patients with low dose hydroxyurea we attempted to de...

journal_title：Clinical and experimental dermatology

authors： Kumar B,Saraswat A,Kaur I

更新日期：2002-01-01 00:00:00

abstract：:We report a case of white fibrous papulosis of the neck in a 70-year-old Iranian woman. To date this recently reported entity has only been described in Japanese patients. This asymptomatic eruption characteristically affects the posterior neck. The pale papules are round to oval 2-3 mm in diameter, and not follicular...

journal_title：Clinical and experimental dermatology

authors： Cerio R,Gold S,Jones EW

更新日期：1991-05-01 00:00:00