A case of dermatopathia pigmentosa reticularis with wiry scalp hair and digital fibromatosis resulting from a recurrent KRT14 mutation.

Abstract:

:We report a patient of Malay ancestry with dermatopathia pigmentosa reticularis (DPR) resulting from a recurrent KRT14 p.R125C mutation. The patient has reticulate hyperpigmentation over his trunk and proximal limbs, together with onychodystrophy. Despite the absence of noncicatricial alopecia, he has acral nonscarring blisters, palmoplantar hyperkeratosis and hypoplastic dermatoglyphics, in addition to unusual abnormalities such as wiry scalp hair and digital fibromatous thickening.

journal_name

Clin Exp Dermatol

authors

Goh BK,Common JE,Gan WH,Kumarasinghe P

doi

10.1111/j.1365-2230.2008.02950.x

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

340-3

issue

3

eissn

0307-6938

issn

1365-2230

pii

CED2950

journal_volume

34

pub_type

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