Secukinumab for treatment of psoriasis: does secukinumab precipitate or promote the presentation of cutaneous T-cell lymphoma?

abstract：:Pseudoepitheliomatous keratotic and micaceous balanitis (PKMB) is an uncommon premalignant condition involving the glans penis. We report the case of an 86-year-old man who presented with phimosis and pain on retracting his foreskin. He had previously undergone circumcision, which revealed a hyperkeratotic plaque with...

journal_title：Clinical and experimental dermatology

authors： Choo KJL,Ng SK,Sim CS,Cheng SWN

更新日期：2017-06-01 00:00:00

abstract：:It is only in the past 10 years that the allergenic potential of topical corticosteroids has been fully realized. This has an important impact on the management of patients with chronic eczematous eruptions. Nonhalogenated topical steroids are more frequent sensitizers than halogenated molecules. Tixocortol pivalate a...

journal_title：Clinical and experimental dermatology

authors： English JS

更新日期：2000-06-01 00:00:00

abstract：:Intravenous (IV) calcium is usually given to temporarily treat the effects of hyperkalaemia on muscle and heart. When extravasation of a calcium gluconate infusion occurs, there may be rapid and marked swelling and erythema, with signs of soft-tissue necrosis or infection, and ensuing extensive local calcification, ca...

journal_title：Clinical and experimental dermatology

authors： Celbek G,Gungor A,Albayrak H,Kir S,Guvenc SC,Aydin Y

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Port-wine stains (PWS) are congenital capillary malformations that persist throughout life. Laser therapy is a common treatment for PWS, and pulsed-dye laser is the current treatment of choice. AIM:To compare the clinical results on untreated PWS of two dye lasers with different wavelengths and pulse durati...

journal_title：Clinical and experimental dermatology

authors： Frohm Nilsson M,Passian S,Wiegleb Edstrom D

更新日期：2010-03-01 00:00:00

abstract：:Guadeloupe is a French Caribbean island, with a population of mainly African ancestry, and a high standard of living. We recorded the dermatological diagnoses in 5000 new patients attending dermatologists. The main diagnoses were acne (16.4%), superficial mycoses (12.8%), and eczema (10.5%). Diseases considered to be ...

journal_title：Clinical and experimental dermatology

authors： Mahé A,Mancel E

更新日期：1999-09-01 00:00:00

abstract：:A retrospective study was made of the incidence of cutaneous melanoma among the population of the district of Rijeka (Croatia) during the period 1977-96. A total of 397 patients with cutaneous melanoma was documented during this period. Over the 20-year period the incidence of the tumour increased, the mean annual rat...

journal_title：Clinical and experimental dermatology

authors： Zamolo G,Gruber F,Jonjić A,Cabrijan L,Palle M,Grubisić-Greblo H

更新日期：2000-01-01 00:00:00

abstract：:Vitiligo is a disease characterized by the loss of melanocytes, resulting in progressive depigmentation of skin, and areas of normally pigmented skin can be of cosmetic concern. Several options have been tried to remove the pigment and make the skin a more even colour. We present an easy and effective therapeutic proc...

journal_title：Clinical and experimental dermatology

authors： Di Nuzzo S,Masotti A

更新日期：2010-03-01 00:00:00

abstract：:It is a common experience that many Spitz naevi deviate from the idealized or stereotypical representation found in the literature, often causing considerable difficulties in distinguishing them from melanoma. The diagnostic term 'atypical Spitz naevus' is used to describe lesions that deviate from the typical appeara...

journal_title：Clinical and experimental dermatology

authors： de Giorgi V,Sestini S,Massi D,Papi F,Lotti T

更新日期：2008-05-01 00:00:00

abstract：:Lipoid proteinosis is an autosomal recessive condition associated with variable scarring and infiltration of skin and mucosae. The disorder has recently been shown to result from loss-of-function mutations in the extracellular matrix protein 1 gene (ECM1) on 1q21. Extracellular matrix protein 1 has important physiolog...

journal_title：Clinical and experimental dermatology

authors： Chan I,El-Zurghany A,Zendah B,Benghazil M,Oyama N,Hamada T,McGrath JA

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Epidemiological and clinical data suggest that actinic damage to the skin is an important predictor of skin carcinogenesis. AIM:To investigate the association of squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) with sun-damage alterations seen by histopathology. METHOD:In the current prospectiv...

journal_title：Clinical and experimental dermatology

authors： Apalla Z,Calzavara-Pinton P,Lallas A,Argenziano G,Kyrgidis A,Crotti S,Facchetti F,Monari P,Gualdi G

更新日期：2016-01-01 00:00:00

abstract：:Human Herpesvirus 8 (HHV-8) has been implicated in the pathogenesis of Kaposi's sarcoma (KS). In this paper we attempted to confirm the connection between dialysis, HHV-8, and KS by examining the case of an elderly haemodialysis nonimmunosuppressed male patient with end-stage renal disease, who developed KS. By using ...

journal_title：Clinical and experimental dermatology

authors： Metaxa-Mariatou V,Chiras T,Loli A,Gazouli M,Vallis D,Nasioulas G

更新日期：2004-03-01 00:00:00

abstract：:We describe the results of a single-centre, double-blind, vehicle-controlled, parallel group study on the quantitative effects of 2% fusidic acid lotion (Fucidin lotion) in facial acne vulgaris. The trial was completed by 52 patients aged 15-25 years with mild to moderate acne who had been randomized to either Fucidin...

journal_title：Clinical and experimental dermatology

authors： Sommer S,Bojar R,Cunliffe WJ,Holland D,Holland KT,Naags H

更新日期：1997-09-01 00:00:00

abstract：:Schistosomiasis is endemic in many parts of the tropics and subtropics with an estimated 200 million people, at least, infected worldwide. The symptoms and signs of vesical and gastrointestinal forms are readily recognized but ectopic forms are rare even in endemic areas and present a greater diagnostic challenge, par...

journal_title：Clinical and experimental dermatology

authors： Leman JA,Small G,Wilks D,Tidman MJ

更新日期：2001-01-01 00:00:00

abstract：:A peculiar observation published in 1971 by Chernosky et al. is revisited in this paper. An African American mother and three of her four children (two girls and one boy) had hyperpigmented skin areas arranged along Blaschko's lines. According to the current knowledge of formal genetics, a mendelian mode of transmissi...

journal_title：Clinical and experimental dermatology

authors： Happle R

更新日期：2009-10-01 00:00:00

abstract：:Dermatomyositis (DM) in a inflammatory disorder of skeletal muscle and skin closely related to other connective tissue diseases; however, to date, no conclusive immunofluorescence (IMF) data are available for the disorder. The aim of this study was therefore to analyse retrospectively the clinical, histological and di...

journal_title：Clinical and experimental dermatology

authors： Jones SA,Black MM

更新日期：1997-03-01 00:00:00

abstract：:A 72-year-old woman with a 14-year history of urticarial vasculitis (UV) and a 13-year history of bullous pemphigoid (BP) presented with associated progressive chronic lymphocytic leukaemia (CLL). Both skin conditions responded poorly to treatment, until chemotherapy for CLL was commenced. The skin features showed a c...

journal_title：Clinical and experimental dermatology

authors： Kassim JM,Igali L,Levell NJ

更新日期：2015-06-01 00:00:00

abstract：:Dyschromatosis universalis hereditaria is a clinically heterogenous disorder. We report two unrelated Indian patients with dyschromatosis universalis hereditaria, who had generalized and progressive reticulate hyper- and hypo-pigmentation of the skin. The oral mucosa and tongue also showed mottled pigmentation. Intrig...

journal_title：Clinical and experimental dermatology

authors： Sethuraman G,Srinivas CR,D'Souza M,Thappa DM,Smiles L

更新日期：2002-09-01 00:00:00

abstract：:A retrospective case series of 53 female patients with incontinentia pigmenti (IP) including 28 secondary cases (female relatives of probands) was reviewed and compared with other series in an attempt to estimate more accurately the true disease burden of patients with IP. We found that, while the frequency of the fir...

journal_title：Clinical and experimental dermatology

authors： Phan TA,Wargon O,Turner AM

更新日期：2005-09-01 00:00:00

abstract：:Ninety-six patients with a clinical and parasitological diagnosis of cutaneous leishmaniasis were recruited to a comparative randomized clinical trial evaluating the efficacy of topical paromomycin vs. weekly intralesional injections of meglumine antimoniate. The patients were randomly divided into two treatment group...

journal_title：Clinical and experimental dermatology

authors： Faghihi G,Tavakoli-kia R

更新日期：2003-01-01 00:00:00

abstract：:We present the case of a 68-year-old woman who developed a painful subcutaneous tumour in the sacral region. Histological examinations revealed a characteristic zonal pattern with a central zone of liquefactive necrosis, surrounded by proliferated atypical fibroblasts and prominent vessels, indicating ischaemic fascii...

journal_title：Clinical and experimental dermatology

authors： Kaneko T,Rokunohe D,Takiyoshi N,Minakawa S,Nakano H,Sawamura D

更新日期：2016-07-01 00:00:00

abstract：:A case of pure non-epidermotropic cutaneous lymphoma in a human immunodeficiency virus-infected patient is reported following a viral opportunistic infection [cytomegalovirus (CMV) hepatitis]. The lymphoid infiltrate was Epstein-Barr virus and CMV negative with a CD30-positive T-cell phenotype. Molecular analysis demo...

journal_title：Clinical and experimental dermatology

authors： Viraben R,Brousset P,Aquilina C,Lamant L

更新日期：1997-11-01 00:00:00

abstract：:Sweet's syndrome (acute febrile neutrophilic dermatosis, SS) may be considered a reactional dermatosis with numerous associated diseases. We describe a rare association between SS and acute sarcoidosis in a 55-year-old woman. The atypical feature of positive tuberculin reaction is discussed. In this association, diagn...

journal_title：Clinical and experimental dermatology

authors： Dadban A,Hirschi S,Sanchez M,Lagrange B

更新日期：2009-03-01 00:00:00

abstract：:The effectiveness of EMLA cream in relieving the discomfort associated with percutaneous infiltration of lignocaine was assessed in a double-blind, placebo-controlled study. Patients undergoing minor skin surgery were divided into two groups, according to the number of lesions requiring surgery. The first group had a ...

journal_title：Clinical and experimental dermatology

authors： Jones SK,Handfield-Jones S,Kennedy CT

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Interferons are molecules with antiviral effects, which have been used for the treatment of verruca for many years. AIMS:To determine if sublesional interferon (IFN)-alpha injection offers an effective alternative treatment for common warts. METHODS:We compared the results of single-dose sublesional IFN ap...

journal_title：Clinical and experimental dermatology

authors： Aksakal AB,Ozden MG,Atahan C,Onder M

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Symptomatic dermographism is a common urticarial condition. There is a need for an objective method to determine the provocation threshold for patients, in order to facilitate individualized diagnosis and treatment. AIM:To compare the dermal responses evoked by a new type of dermographometer (FricTest) with...

journal_title：Clinical and experimental dermatology

authors： Mlynek A,Vieira dos Santos R,Ardelean E,Weller K,Magerl M,Church MK,Maurer M

更新日期：2013-06-01 00:00:00

abstract：:Vitiligo usually begins in childhood with approximately half of the patients manifesting onset of disease prior to the age of 20 years. Treatment options in this age group are few and have disappointing response rates. This study was designed to evaluate the role of narrow-band UVB in the treatment of generalized viti...

journal_title：Clinical and experimental dermatology

authors： Kanwar AJ,Dogra S

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Acne vulgaris is a common chronic skin disease. Inflammation is an important pathogenetic mechanism of acne, and NLRP3 polymorphisms have been reported to be involved in the mediation and occurrence of the inflammation. However, only a few studies on NLRP3 and acne have been reported, and the mechanism remai...

journal_title：Clinical and experimental dermatology

authors： Shen C,Wang QZ,Shen ZY,Yuan HY,Yu WJ,Chen XD,Xu H

更新日期：2019-03-01 00:00:00

abstract：:Encephalocraniocutaneous lipomatosis, or Haberland syndrome, is a rare congenital neurocutaneous disease. It is characterized clinically by unilateral lipomatous hamartomata of the scalp, eyelid, and outer globe of the eye, ipsilateral porencephalic cysts with cortical atrophy, cranial asymmetry, marked developmental ...

journal_title：Clinical and experimental dermatology

authors： Rubegni P,Risulo M,Sbano P,Buonocore G,Perrone S,Fimiani M

更新日期：2003-07-01 00:00:00

abstract：:In Europe and the USA, the incidence of primary nasal natural killer (NK)/T-cell lymphoma is rare. The skin is one of the predilection sites for dissemination. Cutaneous dissemination is a poor prognostic sign and is consistently fatal. We describe the case of a 17-year-old white German girl with a primary nasal NK/T-...

journal_title：Clinical and experimental dermatology

authors： Sandner A,Helmbold P,Winkler M,Gattenlöhner S,Müller-Hermelink HK,Holzhausen HJ

更新日期：2008-08-01 00:00:00

abstract：:Nodular cystic fat necrosis shows a distinctive spectrum of clinical and histological features. Most of the lesions are mobile subcutaneous nodules in regions vulnerable to trauma, such as the elbows, knees, and shins. There have been no reports of an association with other conditions. The histology is characterized b...

journal_title：Clinical and experimental dermatology

authors： Ahn SK,Lee BJ,Lee SH,Lee WS

更新日期：1995-05-01 00:00:00