Papulonodular mucinosis indicating systemic lupus erythematosus.

Abstract:

:We describe an 18-year-old girl with systemic lupus erythematosus (SLE) who had cutaneous papulonodular mucinosis (PNM) as the first sign of SLE. She presented with multiple flesh-coloured papules on the face, abdomen and limbs. Histological examination of a biopsy taken from a papule showed diffuse deposition of mucin throughout the dermis, and direct immunofluorescence of lesional skin showed a dermoepidermal junction band composed of IgG, IgM and C3, consistent with PNM. Investigations showed that that the patient had leucopenia, positive antinuclear and anti-double-stranded DNA antibodies and lupus nephritis. PMN can be an unusual clinical presentation of SLE.

journal_name

Clin Exp Dermatol

authors

Shekari AM,Ghiasi M,Ghasemi E,Kani ZA

doi

10.1111/j.1365-2230.2009.03235.x

subject

Has Abstract

pub_date

2009-12-01 00:00:00

pages

e558-60

issue

8

eissn

0307-6938

issn

1365-2230

pii

CED3235

journal_volume

34

pub_type

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