Cutaneous dissemination of nasal NK/T-cell lymphoma in a young girl.

Abstract:

:In Europe and the USA, the incidence of primary nasal natural killer (NK)/T-cell lymphoma is rare. The skin is one of the predilection sites for dissemination. Cutaneous dissemination is a poor prognostic sign and is consistently fatal. We describe the case of a 17-year-old white German girl with a primary nasal NK/T-cell lymphoma and cutaneous dissemination. She presented with multiple maculopapular patches involving the trunk and thighs, and a 4-week history of headache, fever and fatigue. Biopsies of the skin and the nasal mucosa were taken. Pathological examination of both specimens revealed a NK/T-cell lymphoma. Epstein-Barr virus RNA was detected in the lymphoma cells by in situ hybridization. Unfortunately, the patient died of disease within 1 week.

journal_name

Clin Exp Dermatol

authors

Sandner A,Helmbold P,Winkler M,Gattenlöhner S,Müller-Hermelink HK,Holzhausen HJ

doi

10.1111/j.1365-2230.2008.02777.x

subject

Has Abstract

pub_date

2008-08-01 00:00:00

pages

615-8

issue

5

eissn

0307-6938

issn

1365-2230

pii

CED2777

journal_volume

33

pub_type

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